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#chromatin — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #chromatin, aggregated by home.social.

  1. Second half of morning session on Emerging concepts in gene regulation** **kicks off with

    Songpeng Zu, UCSD
    beyondpie.github.io/

    Comprehensive single-cell analysis of chromatin accessibility in the adult mouse #brain

    117 dissections (!) across whole mouse brain, using SnapATAC2

    Putting data on CATlas (catlas.org)

    biorxiv.org/content/10.1101/20

    #SingleCell
    #chromatin
    #epigenomics
    #neuroscience
    #CSSingleCells23

  2. Lacramioara Bintu of Stanford
    bintulab.com/

    #SingleCell dynamics of gene silencing, epigenetic memory, and #chromatin organization

    silencing & reactivation of expression all-or-none via #histonemethylation

    3 states: active, reversible silent, irreversible silent

    chromatin regulators move proportion of cells in OFF state

    KRAB can "remember" duration of signal, makes heterochromatin, which can spread spatially

    Want to see chromatin state in single cells

    #CSSinglecells23

    1/2

  3. Transcriptional and #chromatin profiling of human blood innate #lymphoid cell subsets sheds light on #HIV1 pathogenesis
    Luban Lab and collaborators
    embopress.org/doi/full/10.1525