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#chromatin — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #chromatin, aggregated by home.social.

  1. This allows condensate behaviour to respond to different inputs, such as lysine #acetylation in IDRs in other CBP domains. It can help to explain how #transcription factors binding to different regions of CBP differentially regulate CBP activity. #enhancers #generegulation #llps #chromatin #imaging #biochemistry #molecularbiology #CellBiology

  2. Extensive multivalent interactions between intrinsically disordered regions in the #BRCA1/#BARD1 #E3 #ligase and #nucleosome substrates facilitate #chromatin recruitment and contribute to histone H2A #ubiquitylation and #DNArepair
    Sam Witus, Rachel Klevit, Weixing Zhao et al
    embopress.org/doi/10.15252/emb

  3. Extensive multivalent interactions between intrinsically disordered regions in the #BRCA1/#BARD1 #E3 #ligase and #nucleosome substrates facilitate #chromatin recruitment and contribute to histone H2A #ubiquitylation and #DNArepair
    Sam Witus, Rachel Klevit, Weixing Zhao et al
    embopress.org/doi/10.15252/emb

  4. Excellent review on NIPBL function and the different roles of STAG1 and STAG2 by Dácil Alonso-Gil and Ana Losada doi.org/10.1016/j.tcb.2023.03. lots to think about in here #chromatin #cdls #chromatindisorders
    #cohesin #genetics

  5. Excellent review on NIPBL function and the different roles of STAG1 and STAG2 by Dácil Alonso-Gil and Ana Losada doi.org/10.1016/j.tcb.2023.03. lots to think about in here #chromatin #cdls #chromatindisorders
    #cohesin #genetics

  6. On this #ThrowbackThursday we go back to our Episode #49 there we caught up with Sandra Hake from the Justus Liebig University in Giessen to talk about her work on variants of core #histones and their role as modulators of #chromatin structure and function. #womeninstem #epigenetics

    Listen here: activemotif.com/podcasts#sandr

  7. Another fruitful @viennabiocenter collaboration, in this case with @golobor @IMBA_Vienna. #cohesin #immunoglobolin #DNA #chromatin #antibody

  8. Another fruitful @viennabiocenter collaboration, in this case with @golobor @IMBA_Vienna. #cohesin #immunoglobolin #DNA #chromatin #antibody

  9. Another fruitful @viennabiocenter collaboration, in this case with @golobor @IMBA_Vienna. #cohesin #immunoglobolin #DNA #chromatin #antibody

  10. Another fruitful @viennabiocenter collaboration, in this case with @golobor @IMBA_Vienna. #cohesin #immunoglobolin #DNA #chromatin #antibody

  11. Another fruitful @viennabiocenter collaboration, in this case with @golobor @IMBA_Vienna. #cohesin #immunoglobolin #DNA #chromatin #antibody

  12. science.org/doi/10.1126/sciadv

    "We report a tightly regulated epigenome landscape change from the germline to embryos that are regulated through differential expression of distinct histone gene clusters. Together, this study reveals that a change from a H3.3- to H3-enriched epigenome during embryogenesis restricts developmental plasticity and uncovers distinct roles for individual H3 genes in regulating germline chromatin."

    #epigenetics #devBio #developmentalBiology #chromosomes #chromatin #histones

  13. A new variation of the #HiC method to study #3Dgenome interactions specifically for open #chromatin. "HiCAR is a robust and sensitive method to analyze open-chromatin-associated genome organization" cell.com/molecular-cell/fullte?

  14. A new variation of the #HiC method to study #3Dgenome interactions specifically for open #chromatin. "HiCAR is a robust and sensitive method to analyze open-chromatin-associated genome organization" cell.com/molecular-cell/fullte?

  15. "This work reveals epigenetic transmission of parental H2A-H2B during DNA replication and identifies cross talk between H3-H4 and H2A-H2B modifications in epigenome propagation. We propose that rapid short-term memory of recycled H2A-H2B modifications facilitates restoration of stable H3-H4 chromatin states."
    cell.com/cell/fulltext/S0092-8.

    #epigenetics #Histones #chromatin #cellularbiology #CellDivision #genomics

  16. Anchoring #3Dgenome & #chromatin contacts to #cellnucleus landmarks: Mapping #nucleolus-associated chromatin interactions using nucleolus #HiC reveals pattern of #heterochromatin interactions.
    @NatureComms doi.org/10.1038/s41467-023-360

  17. Anchoring #3Dgenome & #chromatin contacts to #cellnucleus landmarks: Mapping #nucleolus-associated chromatin interactions using nucleolus #HiC reveals pattern of #heterochromatin interactions.
    @NatureComms doi.org/10.1038/s41467-023-360

  18. Our latest work on computer simulation of #chromatin appeared in its final form today. Fully extruded loops mediated by #cohesin and #CTCF have increased contact probabilities within loops. Microloops manifest without additional factors. Effects depend on nucleosome positions. It is freely available online until end of the year with authors.elsevier.com/a/1g4Hg1S

  19. Our latest work on computer simulation of #chromatin appeared in its final form today. Fully extruded loops mediated by #cohesin and #CTCF have increased contact probabilities within loops. Microloops manifest without additional factors. Effects depend on nucleosome positions. It is freely available online until end of the year with authors.elsevier.com/a/1g4Hg1S

  20. Our latest work on computer simulation of #chromatin appeared in its final form today. Fully extruded loops mediated by #cohesin and #CTCF have increased contact probabilities within loops. Microloops manifest without additional factors. Effects depend on nucleosome positions. It is freely available online until end of the year with authors.elsevier.com/a/1g4Hg1S

  21. Our latest work on computer simulation of #chromatin appeared in its final form today. Fully extruded loops mediated by #cohesin and #CTCF have increased contact probabilities within loops. Microloops manifest without additional factors. Effects depend on nucleosome positions. It is freely available online until end of the year with authors.elsevier.com/a/1g4Hg1S

  22. IF you want to get a quick idea what we are working on see the talk of my PhD student Aymen Attou on youtube at the "Nuclear architecture & Function" symposium in Toulouse youtube.com/watch?v=mPneWhIBRA #chromatin #ctcf #cohesin

  23. I am excited to be at genomic.social #introduction. I am interested in understanding the spatial structure of #chromatin and its regulation e.g. by nucleosome positions or #cohesin. My lab uses Monte Carlo simulations with a resolution of single nucleosomes of regions up to 1 Mbp.

  24. I am excited to be at genomic.social #introduction. I am interested in understanding the spatial structure of #chromatin and its regulation e.g. by nucleosome positions or #cohesin. My lab uses Monte Carlo simulations with a resolution of single nucleosomes of regions up to 1 Mbp.

  25. I am excited to be at genomic.social #introduction. I am interested in understanding the spatial structure of #chromatin and its regulation e.g. by nucleosome positions or #cohesin. My lab uses Monte Carlo simulations with a resolution of single nucleosomes of regions up to 1 Mbp.

  26. I am excited to be at genomic.social #introduction. I am interested in understanding the spatial structure of #chromatin and its regulation e.g. by nucleosome positions or #cohesin. My lab uses Monte Carlo simulations with a resolution of single nucleosomes of regions up to 1 Mbp.