https://www.europesays.com/ie/685339/ Neurons may build their identity after birth, study finds #Als #BrainAtlas #BrainDevelopment #DNAEnhancers #Éire #FruitFlyBrain #GeneRegulation #GeneticRegulation #Glaucoma #IE #Ireland #NeuralDevelopment #NeuralStemCells #NeurologicalDisorders #NeuronDevelopment #NeuronIdentity #Neurons #Neuroscience #NeuroscienceResearch #Parkinson'sDisease #PNAS #ProceedingsOfTheNationalAcademyOfSciences #Science #StowersInstitute #TranscriptionFactors
#transcriptionfactors — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #transcriptionfactors, aggregated by home.social.
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https://www.europesays.com/ie/624994/ Researchers discover smart molecular glue that activates inside oxidative cancer cells #cancer #Cell #Drugs #Éire #Electron #ElectronMicroscopy #Enzyme #Health #hospital #IE #Ireland #Ligase #Microscopy #Protein #Research #StructuralBiology #Transcription #TranscriptionFactors
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LMU researchers reveal how different organs customize their internal clocks
LMU researchers have elucidated how different organs adapt the same clock machinery to regulate their individual needs over…
#NewsBeep #News #Science #CA #Canada #Cell #Chromatin #DNA #Gene #GeneExpression #genes #Kidney #Liver #Protein #Transcription #TranscriptionFactors
https://www.newsbeep.com/ca/848339/ -
LMU researchers reveal how different organs customize their internal clocks
LMU researchers have elucidated how different organs adapt the same clock machinery to regulate their individual needs over…
#NewsBeep #News #Science #AU #Australia #Cell #Chromatin #dna #Gene #GeneExpression #Genes #Kidney #Liver #protein #Transcription #TranscriptionFactors
https://www.newsbeep.com/au/845754/ -
https://www.europesays.com/ie/623609/ LMU researchers reveal how different organs customize their internal clocks #Cell #Chromatin #DNA #Éire #Gene #GeneExpression #Genes #IE #Ireland #Kidney #Liver #Protein #Science #Transcription #TranscriptionFactors
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https://www.europesays.com/ie/518872/ Novel technology maps single-cell DNA-protein interactions #Antibodies #blood #cancer #Cell #DNA #Éire #Enzyme #Gene #Genome #IE #Ireland #medicine #Mutation #Protein #Research #Science #Technology #Transcription #TranscriptionFactors
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Mesenchymal drift may explain how aging cells lose their identity
A new review argues that aging may not be just a collection of molecular defects, but a progressive…
#NewsBeep #News #Science #Aging #AU #Australia #Cell #Chronic #Cytokines #dna #Embryogenesis #Fibroblast #Fibrosis #Genomic #Inflammation #Transcription #TranscriptionFactors
https://www.newsbeep.com/au/707805/ -
https://www.europesays.com/ie/366706/ Innovative peptide stapling system targets hard-to-treat cancers #Assay #bacteria #Bacterial #cancer #Cell #Colorectal #ColorectalCancer #DrugDiscovery #Éire #Health #IE #Ireland #LivingCells #peptides #Research #Technology #Therapeutics #Transcription #TranscriptionFactors
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https://www.europesays.com/ie/364995/ New method isolates true transcription factor targets in tuberculosis bacteria #bacteria #Cell #DNA #Drugs #Éire #Enzyme #Gene #GeneExpression #Genes #Genomic #genomics #IE #Ireland #Laboratory #LivingCells #Pathogen #Polymerase #Protein #RNA #Science #Therapeutics #Transcription #TranscriptionFactors #tuberculosis
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https://www.europesays.com/ie/331730/ Transcription factor HOXD13 drives melanoma growth and immune evasion #Adenosine #Angiogenesis #blood #BloodVessel #cancer #Cell #DNA #Éire #Gene #Genetic #GrowthFactor #IE #ImmuneSystem #Ireland #MedicalResearch #medicine #Melanoma #Molecule #Nutrients #Oxygen #Protein #Receptor #Research #skin #SkinCancer #Technology #Transcription #TranscriptionFactors #Tumor #Vascular #VEGF
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https://www.europesays.com/ie/228601/ New findings show why the human intestine uniquely presents gluten to T cells #Antigen #CeliacDisease #Cell #CellDevelopment #CoeliacDisease #Cytometry #DendriticCell #Éire #FlowCytometry #Gene #Genes #gluten #Glycoprotein #Health #IE #immunity #InVivo #Interferon #InterferonGamma #Ireland #Knockout #Ligand #Necrosis #Organoids #peptides #Protein #Receptor #RetinoicAcid #StemCells #Transcription #TranscriptionFactors #Tumor #TumorNecrosisFactor
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https://www.europesays.com/ie/164095/ PTGES3 emerges as key regulator of androgen receptor in prostate cancer #Androgen #cancer #CRISPR #DNA #Éire #Enzyme #Gene #GeneExpression #Genes #Genetics #Genome #Health #Hormone #IE #Ireland #medicine #oncology #Prostate #ProstateCancer #Protein #Receptor #Research #therapy #Transcription #TranscriptionFactors #Tumor #Urology
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📣 New Article from Network and Systems Medicine on #ScienceOpen!
🆕📄 'Identification of Transcriptional Regulators Using a Combined Disease Module Identification and Prize-Collecting Steiner Tree Approach' ➡️ https://drugrepocentral.scienceopen.com/hosted-document?doi=10.14293/NSM.25.1.0003
#REPO4EU #NetworkMedicine #Bioinformatics #TranscriptionFactors
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Profound study on #geneRegulation in E. coli: #transcriptionFactors generally stabilize interaction with RNA polymerase and thus reduce expression range across promoters -> better maintenance of homeostasis. https://www.science.org/doi/abs/10.1126/science.adv2064
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Researchers identify genetic toolkit to reprogram cells into immune sentinels
An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #cancer #Cell #DendriticCell #Genetic #immunesystem #immunity #immunotherapy #invitro #invivo #medicine #Research #Science #Transcription #TranscriptionFactors
https://www.newsbeep.com/us/118987/ -
Ancient viral DNA found to regulate human gene expression
A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as…
#NewsBeep #News #Genetics #AU #Australia #dna #Evolution #Gene #GeneExpression #Genes #Genetic #Genome #research #Science #StemCells #Transcription #TranscriptionFactors
https://www.newsbeep.com/au/4960/ -
Ancient viral DNA found to regulate human gene expression
A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as…
#NewsBeep #News #Genetics #CA #Canada #DNA #Evolution #Gene #GeneExpression #genes #Genetic #Genome #research #Science #StemCells #Transcription #TranscriptionFactors
https://www.newsbeep.com/ca/7213/ -
We also saw a shift in TF activity.
Footprinting showed increased NFI binding, especially NFIB, in late-born cohorts. These neurons activate maturation modules faster — possibly guided by chromatin remodeling during neurogenesis.
#NewsMayerlab #TFfootprints #TranscriptionFactors #scATACseq
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Scleraxis (Genetics 🧬)
The scleraxis protein is a member of the basic helix-loop-helix superfamily of transcription factors. Currently two genes have been identified to code for identical scleraxis proteins.
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🧬 Why do humans think so differently from Neanderthals? The answer might lie in gene switches, not the genes themselves.
🔗 Evolution is in the details: Regulatory differences in modern human and Neanderthal. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.052
📚 CSBJ: https://www.csbj.org/
#Genomics #Neuroscience #Evolution #HumanOrigins #NeanderthalDNA #AutismResearch #HumanEvolution #GeneRegulation #Bioinformatics #ASD #RegulatoryGenomics #TranscriptionFactors
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Scientists recreate mouse stem cells f. gene older than animal life
https://www.sciencedaily.com/releases/2024/11/241118125716.htm* unicellular Sox, POU transcription factors
* created mouse stem cells capable of gen. fully dev. mouse
* reshapes understanding of genetic/evol. origins of stem cells
* poss. critical for advent of stem cells, multicellularityEmergence of Sox & POU transcript. factors predates origins of animal stem cells
https://www.nature.com/articles/s41467-024-54152-x#StemCells #evolution #MolecularBiology #TranscriptionFactors #Sox #Pou
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Researchers challenge longstanding theories in cellular reprogramming
https://www.sciencedaily.com/releases/2024/11/241101123641.htm* claim: neural crest stem cells = source of reprogrammed neurons found by other researchers
* refutes: any developed cell can be induced to switch identity to completely unrelated cell type thru infusion of transcription factorsNeural crest precursors f. skin are primary source of directly reprogrammed neurons
https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(24)00291-1#StemCells #MolecularBiology #CellBiology #TranscriptionFactors
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Hello. My name is Christopher Chase Bolt. Everyone calls me Chase. And this is my #ScienceMastadon introduction
I love #TranscriptionFactors and #Enhancers and their relationship to #GeneExpression. During my PhD at the #UniversityOfIllinois I studied the relationship between structural mutations in the genome and how they affect gene expression. #TissueCulture and #MouseGenetics n/n