#bcell — Public Fediverse posts

Pipeline release! nf-core/airrflow v5.1.0 - 5.1.0 - Ventus!
B-cell and T-cell Adaptive Immune Receptor Repertoire (AIRR) sequencing analysis pipeline using the Immcantation framework
Please see the changelog: https://github.com/nf-core/airrflow/releases/tag/5.1.0

#airr #bcell #immcantation #immunorepertoire #repseq #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/airrflow v5.1.0 - 5.1.0 - Ventus!
B-cell and T-cell Adaptive Immune Receptor Repertoire (AIRR) sequencing analysis pipeline using the Immcantation framework
Please see the changelog: https://github.com/nf-core/airrflow/releases/tag/5.1.0

#airr #bcell #immcantation #immunorepertoire #repseq #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/airrflow v5.0.0 - Tarantallegra!
B-cell and T-cell Adaptive Immune Receptor Repertoire (AIRR) sequencing analysis pipeline using the Immcantation framework
Please see the changelog: https://github.com/nf-core/airrflow/releases/tag/5.0.0

#airr #bcell #immcantation #immunorepertoire #repseq #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/airrflow v5.0.0 - Tarantallegra!
B-cell and T-cell Adaptive Immune Receptor Repertoire (AIRR) sequencing analysis pipeline using the Immcantation framework
Please see the changelog: https://github.com/nf-core/airrflow/releases/tag/5.0.0

#airr #bcell #immcantation #immunorepertoire #repseq #nfcore #openscience #nextflow #bioinformatics

Epigenetic regulators like EZH2 are mutated in #Bcell #lymphoma, but what is their effect? This study reveals a role for mutant EZH2 in lymphomagenesis, using a new method for measuring #epigenetic heterogeneity & intra- #chromatin connectivity in #cancer @PLOSBiology https://plos.io/4mZcS8n

Epigenetic regulators like EZH2 are mutated in #Bcell #lymphoma, but what is their effect? This study reveals a role for mutant EZH2 in lymphomagenesis, using a new method for measuring #epigenetic heterogeneity & intra- #chromatin connectivity in #cancer @PLOSBiology https://plos.io/4mZcS8n

Pipeline release! nf-core/airrflow v4.3.1 - v4.3.1 Revelio bugfix!

Please see the changelog: https://github.com/nf-core/airrflow/releases/tag/4.3.1

#airr #bcell #immcantation #immunorepertoire #repseq #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/airrflow v4.3.1 - v4.3.1 Revelio bugfix!

Please see the changelog: https://github.com/nf-core/airrflow/releases/tag/4.3.1

#airr #bcell #immcantation #immunorepertoire #repseq #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/airrflow v4.3.0 - v4.3.0 - Revelio!

Please see the changelog: https://github.com/nf-core/airrflow/releases/tag/4.3.0

#airr #bcell #immcantation #immunorepertoire #repseq #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/airrflow v4.3.0 - v4.3.0 - Revelio!

Please see the changelog: https://github.com/nf-core/airrflow/releases/tag/4.3.0

#airr #bcell #immcantation #immunorepertoire #repseq #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/airrflow v4.2.0 - v4.2.0 Evanesco!

Please see the changelog: https://github.com/nf-core/airrflow/releases/tag/4.2.0

#airr #bcell #immcantation #immunorepertoire #repseq #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/airrflow v4.2.0 - v4.2.0 Evanesco!

Please see the changelog: https://github.com/nf-core/airrflow/releases/tag/4.2.0

#airr #bcell #immcantation #immunorepertoire #repseq #nfcore #openscience #nextflow #bioinformatics

The transcription factor Pax5 regulates #Bcell development & commitment, and scientists in the lab of Meinrad Busslinger have found out how. Out now in @JExpMed.
Our interview with first author Sarah Grünbacher 👉🏼 https://www.imp.ac.at/news/article/immunologists-reveal-how-the-pax5-protein-regulates-b-cell-development-and-commitment
The paper 👉🏼 https://rupress.org/jem/article/220/12/e20230260/276276/Essential-role-of-the-Pax5-C-terminal-domain-in

The transcription factor Pax5 regulates #Bcell development & commitment, and scientists in the lab of Meinrad Busslinger have found out how. Out now in @JExpMed.
Our interview with first author Sarah Grünbacher 👉🏼 https://www.imp.ac.at/news/article/immunologists-reveal-how-the-pax5-protein-regulates-b-cell-development-and-commitment
The paper 👉🏼 https://rupress.org/jem/article/220/12/e20230260/276276/Essential-role-of-the-Pax5-C-terminal-domain-in

Local enhancers of the #PAIR4 regulatory module promote distal V-H gene #recombination at the #Igh locus and contribute to #Bcell receptor repertoire diversification

Louisa Hil et al Busslinger lab @IMPvienna

https://www.embopress.org/doi/full/10.15252/embj.2022112741

Local enhancers of the #PAIR4 regulatory module promote distal V-H gene #recombination at the #Igh locus and contribute to #Bcell receptor repertoire diversification

Louisa Hil et al Busslinger lab @IMPvienna

https://www.embopress.org/doi/full/10.15252/embj.2022112741

EMBO Journal Issue 4/23:
- Commentary on #creativity needs in research
- #Degron recognition in orphan complex subunits by CLR4-DCAF12 E3 #ubiquitin #ligase
- #Plasmamembrane topography of #IgM #Bcell receptors
- #YAP roles and regulation in #tumorigenesis
- #Brassinosteroid interplay with #katanin #microtubule severing

Cover by Satarupa Bhaduri, Analine Aguayo, Sonya Neal et al
https://www.embopress.org/toc/14602075/2023/42/4

EMBO Journal Issue 4/23:
- Commentary on #creativity needs in research
- #Degron recognition in orphan complex subunits by CLR4-DCAF12 E3 #ubiquitin #ligase
- #Plasmamembrane topography of #IgM #Bcell receptors
- #YAP roles and regulation in #tumorigenesis
- #Brassinosteroid interplay with #katanin #microtubule severing

Cover by Satarupa Bhaduri, Analine Aguayo, Sonya Neal et al
https://www.embopress.org/toc/14602075/2023/42/4

#Plasmamembrane topography governs the 3D dynamic localization of #IgM #Bcell #antigenreceptor clusters

Deniz Saltukoglu, Michael Reth et al at University Freiburg use high-resolution #microscopy on the #Burkitt’s Lymphoma model Ramos B-cell line to reveal surface topographical features facilitating screening of #antigens

https://www.embopress.org/doi/10.15252/embj.2022112030

#Plasmamembrane topography governs the 3D dynamic localization of #IgM #Bcell #antigenreceptor clusters

Deniz Saltukoglu, Michael Reth et al at University Freiburg use high-resolution #microscopy on the #Burkitt’s Lymphoma model Ramos B-cell line to reveal surface topographical features facilitating screening of #antigens

https://www.embopress.org/doi/10.15252/embj.2022112030

New from Prof. Shane Crotty and Yu Kato at LJI and Andrew G Letizia at the Naval Medical Research Center:

"Memory B-Cell Development After Asymptomatic or Mild Symptomatic SARS-CoV-2 Infection" https://doi.org/10.1093/infdis/jiac319

Read for a close look at spike #antibody titers, pseudovirus neutralizing antibody titers, and memory #Bcell responses among #SARSCoV2 PCR-positive Marine recruits who either reported asymptomatic or symptomatic infection. #OpenAccess #COVID19 #immunology #InfectiousDisease

New from Prof. Shane Crotty and Yu Kato at LJI and Andrew G Letizia at the Naval Medical Research Center:

"Memory B-Cell Development After Asymptomatic or Mild Symptomatic SARS-CoV-2 Infection" https://doi.org/10.1093/infdis/jiac319

Read for a close look at spike #antibody titers, pseudovirus neutralizing antibody titers, and memory #Bcell responses among #SARSCoV2 PCR-positive Marine recruits who either reported asymptomatic or symptomatic infection. #OpenAccess #COVID19 #immunology #InfectiousDisease