#geneediting — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #geneediting, aggregated by home.social.
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Colossal Biosciences Is Making Jurassic Park Look Like a Pitch Deck
Modern biotechnology labs are driving advances in gene editing and de-extinction researchDear Cherubs, Dallas has apparently decided extinction is just a product category. Colossal Biosciences is now a billionaire-level biotech spectacle, with the company saying its latest Series C brought total funding to $615 million and ABC News reporting a roster of celebrity backers that includes Tom Brady, Tiger Woods, Paris Hilton and Peter Jackson. Dallas Innovates also reported that the CIA’s venture arm, In-Q-Tel, invested in Colossal back in 2022.
The result is a company that sounds like it was brainstormed by a film studio, a venture fund and a very committed science teacher. Colossal says it is working on de-extinction projects tied to the woolly mammoth, dodo, thylacine and dire wolf, using gene editing, synthetic biology and related conservation tools. So no, this is not literally Jurassic Park; it is more like Jurassic Park after legal review and a lot of grant money.
THE TEA, BUT WITH MICROPIPETTES
In April, Reuters reported that Colossal announced three genetically engineered wolf pups and called them the world’s first successfully “de-extincted” animals, while outside experts were more cautious and described them as genetically modified gray wolves with added dire-wolf traits. ABC News said Colossal edited gray wolf cells at multiple sites and noted the two species are about 99.5% genetically identical, which is a very impressive number and also a reminder that biology is rude and complicated.
That is the key detail the movie version never pauses for: the company is not dusting off a frozen dinosaur and pressing play. It is using ancient DNA, gene editing and surrogate biology to create something that resembles an extinct species closely enough to trigger headlines, debates and a healthy amount of side-eye. The label “de-extincted” is doing a lot of heavy lifting here.
WHY THE MONEY FLOWS
The money makes more sense when you look at the technology stack. Dallas Innovates reported that In-Q-Tel said its interest in Colossal was “less about the mammoths and more about the capability,” while Colossal’s own materials say the work could scale CRISPR, synthetic biology, artificial wombs and genomic preservation platforms. In other words, the extinct-animal angle is the headline; the platform is the business.
Colossal has also built a pop-culture-friendly halo around the science. Its advisory board page lists Tom Brady and George R.R. Martin among its cultural advisors, which is exactly the kind of sentence that makes the internet stop scrolling for a second. That is the trick here: make de-extinction feel part science, part blockbuster, part meme, and suddenly the cap table looks almost inevitable.
The hot take is simple: this is not a cartoonish clone factory, and it is not pure hype either. It is a very expensive attempt to push gene editing, cloning-adjacent methods and reproductive tech into territory that could one day matter for conservation as much as spectacle. The dinosaurs are still fiction, but the lab bills are extremely real.
Sources list
The Thisclaimer logo blends a classic warning symbol with a brain icon to represent critical thinking, curiosity, and thoughtful disclaimers. #animals #biotechnology #cia #colossalBiosciences #crispr #deExtinction #direWolf #geneEditing #inQTel #nature #news #science #syntheticBiology #texasStartup
ABC News — https://abcnews.go.com/US/dire-wolf-revived-biotech-companys-de-extinction-process/story?id=120558562
Reuters — https://www.reuters.com/science/us-company-resurrects-extinct-dire-wolf-or-some-version-it-2025-04-08/
Dallas Innovates — https://dallasinnovates.com/mammoth-interest-the-cia-invests-in-dallas-based-colossal-biosciences/
Colossal Biosciences — https://colossal.com/colossal-secures-200m-to-accelerate-de-extinction-and-genomic-innovation/
Colossal Biosciences — https://colossal.com/advisors/
Wikimedia Commons (Laboratory.jpg) — https://commons.wikimedia.org/wiki/File:Laboratory.jpg -
Custom RNA Oligos Market in Italy | Report – IndexBox
Italy Custom RNA Oligos Marke…
#Italy #Europe #Europa #EU #2'-O-methyl) #Antisenseoligonucleotideresearch #biopharmamarketreport #CustomRNAoligos #Diagnosticprobedevelopment #forecast #Geneediting(CRISPRgRNA) #Genesilencing(siRNA #marketanalysis #Massspectrometry(MS)forQC #Modificationchemistry(2'-fluoro #Reverse-phaseandion-exchangeHPLCpurification #RNAi) #Solid-phasephosphoramiditesynthesis
https://www.europesays.com/italy/14486/ -
🦠 Could we outsmart antibiotic resistance by turning bacteria against themselves?
🔗 Rational Targeting and gRNA Design for Enhancing Quorum Quenching in Pseudomonas aeruginosa PAO1. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0089
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#AntimicrobialResistance #AMR #CRISPR #GeneEditing #SyntheticBiology #SystemsBiology #Microbiology #Biotechnology #DrugResistance #QuorumSensing #Biofilms #Genomics
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🦠 Could we outsmart antibiotic resistance by turning bacteria against themselves?
🔗 Rational Targeting and gRNA Design for Enhancing Quorum Quenching in Pseudomonas aeruginosa PAO1. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0089
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#AntimicrobialResistance #AMR #CRISPR #GeneEditing #SyntheticBiology #SystemsBiology #Microbiology #Biotechnology #DrugResistance #QuorumSensing #Biofilms #Genomics
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🦠 Could we outsmart antibiotic resistance by turning bacteria against themselves?
🔗 Rational Targeting and gRNA Design for Enhancing Quorum Quenching in Pseudomonas aeruginosa PAO1. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0089
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#AntimicrobialResistance #AMR #CRISPR #GeneEditing #SyntheticBiology #SystemsBiology #Microbiology #Biotechnology #DrugResistance #QuorumSensing #Biofilms #Genomics
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🦠 Could we outsmart antibiotic resistance by turning bacteria against themselves?
🔗 Rational Targeting and gRNA Design for Enhancing Quorum Quenching in Pseudomonas aeruginosa PAO1. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0089
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#AntimicrobialResistance #AMR #CRISPR #GeneEditing #SyntheticBiology #SystemsBiology #Microbiology #Biotechnology #DrugResistance #QuorumSensing #Biofilms #Genomics
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🦠 Could we outsmart antibiotic resistance by turning bacteria against themselves?
🔗 Rational Targeting and gRNA Design for Enhancing Quorum Quenching in Pseudomonas aeruginosa PAO1. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0089
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#AntimicrobialResistance #AMR #CRISPR #GeneEditing #SyntheticBiology #SystemsBiology #Microbiology #Biotechnology #DrugResistance #QuorumSensing #Biofilms #Genomics
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In our latest #NewTech feature, Cheng et al. demonstrate the successful use of a Cas12a base editor for trait #development, and report improved Cas12a CBEs and ABEs for precise base editing in #plants.
https://doi.org/10.1111/jipb.70249
@WileyLifeSci
#PlantSci #JIPB #CropSci #GeneEditing #botany -
In our latest #NewTech feature, Cheng et al. demonstrate the successful use of a Cas12a base editor for trait #development, and report improved Cas12a CBEs and ABEs for precise base editing in #plants.
https://doi.org/10.1111/jipb.70249
@WileyLifeSci
#PlantSci #JIPB #CropSci #GeneEditing #botany -
A non-browning #Banana has been approved in over 10 countries, representing 70% of global production and 30% of the consumer market; it extends shelf-life and can reduce #FoodWaste. A variety resistant to Panama Disease is in the making: www.fruitnet.com/fruitnet/gen... #PlantBreeding #GeneEditing
Gene-edited banana approved in... -
A non-browning #Banana has been approved in over 10 countries, representing 70% of global production and 30% of the consumer market; it extends shelf-life and can reduce #FoodWaste. A variety resistant to Panama Disease is in the making: www.fruitnet.com/fruitnet/gen... #PlantBreeding #GeneEditing
Gene-edited banana approved in... -
https://www.europesays.com/uk/897423/ 20 Most Promising Young Plant Breeders in Europe 2026 #CropBreeding #Environment&Climate #EU #Europe #European #FeaturedEurope #GeneEditing #Industry #Innovation #News #PlantBreeding #PlantBreedingInnovation #SeedWorldEurope
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#FoodSafety: Bread made from gene-edited wheat showed much reduced levels of acrylamide, a common but toxic and probably carcinogenic compound. Conventional breeding would unlikely deliver similar improvements: www.rothamsted.ac.uk/news/ultra-l... #Wheat #CRISPR #GeneEditing #PlantBreeding #Health
Ultra-Low Asparagine Wheat Dev... -
#FoodSafety: Bread made from gene-edited wheat showed much reduced levels of acrylamide, a common but toxic and probably carcinogenic compound. Conventional breeding would unlikely deliver similar improvements: www.rothamsted.ac.uk/news/ultra-l... #Wheat #CRISPR #GeneEditing #PlantBreeding #Health
Ultra-Low Asparagine Wheat Dev... -
In an online survey in Spain (n=500), participants prioritised pesticide reduction when assessing potential benefits of #CRISPR. Two groups emerged: one motivated by environmental #sustainability, the other by health and sensory quality: doi.org/10.1186/s401... #GeneEditing #PlantBreeding #Health
Which traits drive consumer pr... -
In an online survey in Spain (n=500), participants prioritised pesticide reduction when assessing potential benefits of #CRISPR. Two groups emerged: one motivated by environmental #sustainability, the other by health and sensory quality: doi.org/10.1186/s401... #GeneEditing #PlantBreeding #Health
Which traits drive consumer pr... -
In an online survey in Spain (n=500), participants prioritised pesticide reduction when assessing potential benefits of #CRISPR. Two groups emerged: one motivated by environmental #sustainability, the other by health and sensory quality: doi.org/10.1186/s401... #GeneEditing #PlantBreeding #Health
Which traits drive consumer pr... -
In an online survey in Spain (n=500), participants prioritised pesticide reduction when assessing potential benefits of #CRISPR. Two groups emerged: one motivated by environmental #sustainability, the other by health and sensory quality: doi.org/10.1186/s401... #GeneEditing #PlantBreeding #Health
Which traits drive consumer pr... -
In an online survey in Spain (n=500), participants prioritised pesticide reduction when assessing potential benefits of #CRISPR. Two groups emerged: one motivated by environmental #sustainability, the other by health and sensory quality: doi.org/10.1186/s401... #GeneEditing #PlantBreeding #Health
Which traits drive consumer pr... -
https://www.europesays.com/ie/352378/ Engineers develop highly precise gene editor for safer cystic fibrosis treatments #bacteria #Bioengineering #CysticFibrosis #Cytosine #DNA #Drugs #Éire #Enzyme #fibrosis #Gene #GeneEditing #Genetic #Health #IE #InfectiousDiseases #Ireland #Lungs #medicine #PrecisionMedicine #Research #Technology #therapy
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👶🔬 The New York Times delivers another zinger: a baby gets a gene-editing tune-up and suddenly #miracles are real! 🙄 Just disable your ad blocker and enable JavaScript to witness the future of medicine—or maybe just to read about it while your browser weeps. 💻💧
https://www.nytimes.com/2025/05/15/health/gene-editing-personalized-rare-disorders.html #geneediting #futureofmedicine #biotechnology #NewYorkTimes #HackerNews #ngated -
‘A new beginning’: US man who received pig kidney transplant returns home
> Scientists at the hospital partnered with biotechnology company eGenesis to genetically edit the kidney for transplant, a multi-year process that removed harmful pig genes from the organ and inactivated porcine retroviruses that could potentially cause infection.
https://www.theguardian.com/us-news/2024/apr/04/pig-kidney-transplant
#biotech #medicine #geneticModification #geneEditing #geneticallyModified #gm #health #renalFailure #kidneyFailure #kidney
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Decorated my headset and covered the Facebook logo it's also unlocked to install apps like side quest and alvr and to test 3d modeling and the gene editing software which is being developed for both vr but also qt but was got for vulpine labs although it's not it's full purpose but rather half of it the other half was for fun
#fuckfacebook #OculusQuest2 #devkit #adb #vr #facebookisntmeta #oculusnotfacebook #kitsune #geneediting #QtCreator #linux #steamvr #android
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#US #approves first #geneediting #treatment, #Casgevy, for #SickleCellDisease.
#SickleCell, an inherited #blood #disorder, causes #redbloodcells to become misshapen half moons that get stuck inside #blood #vessels, #restricting #bloodflow and causing what are known as #paincrises.
#Women #Transgender #LGBTQ #LGBTQIA #Health #Healthcare #Progress #BlackMastodon
https://www.cnbc.com/2023/12/08/casgevy-first-crispr-gene-editing-treatment-approved-in-us.html
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#Weeds in your #rice? Exploiting novel endogenous glyphosate-tolerant alleles has promising potential for weed control in rice breeding. Find out how it works! https://doi.org/10.1111/jipb.13543
@wileyplantsci
#JIPB #PlantSci #CropSci #cytosine #adenine #GeneEditing #evolution #botany #PLantScience -
#Weeds in your #rice? Exploiting novel endogenous glyphosate-tolerant alleles has promising potential for weed control in rice breeding. Find out how it works! https://doi.org/10.1111/jipb.13543
@wileyplantsci
#JIPB #PlantSci #CropSci #cytosine #adenine #GeneEditing #evolution #botany #PLantScience -
Many in vitro #CRISPR knock-in approaches use small molecule drugs to improve the efficiency of homology-directed repair, but these drugs may or may not be safe in vivo. In this paper from #NatureBiotechnology, the authors find that an FDA-approved therapy, fludarabine, can be used for a similar purpose. Still a long ways to go before any genetic knock-ins are routinely done in vivo, but making progress toward doing so safely: https://www.nature.com/articles/s41587-022-01240-2 #science #medicine #GeneEditing #AAV
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My initial #introduction was a bit sparse, so here are more areas where I engage: #health #healthcare #medicine #physicianscientist #MDPhD #DoubleDocs #science #research #academic #biology #humandisease #aging #hematology #haematology #hematopoiesis #blood #stemcells #germline #somaticgenetics #mosaicism #mutation #SNV #mCA #genetics #genomics #populationgenetics #AML #MDS #MPN #myeloid #ClonalHematopoiesis #CHIP #inflammation #bonemarrow #HSC #biobank #molecularbiology #geneediting #CRISPR #NGS