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#antidepressant — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #antidepressant, aggregated by home.social.

  1. 1/ I’ve halved my #antidepressant #sertaline (from 100mg to 50mg) as my #seasonalaffectivedisorder #sad and #bipolar means that I get a bit over excitable / energetic / aggressive when the sun is out. The irritability and aggression are obviously the big problems here. I think dropping the dose has taken the edge off but it also hits my confidence and makes me more needy in my #relationships .
    #mentalhealth

  2. Proud to share my latest first authorship! This is the first #clinicaltrial testing IV #arketamine for #bipolar #depression. Subjects received two infusions one week apart—0.5 mg/kg first and then 1 mg/kg, showing rapid-acting #antidepressant properties.

    doi.org/10.1016/j.jpsychires.2

  3. Proud to share my latest first authorship! This is the first #clinicaltrial testing IV #arketamine for #bipolar #depression. Subjects received two infusions one week apart—0.5 mg/kg first and then 1 mg/kg, showing rapid-acting #antidepressant properties.

    doi.org/10.1016/j.jpsychires.2

  4. Excited to share our pioneer pilot crossover #RCT testing arketamine for treatment-resistant #depression (TRD). Racemic #ketamine is a mixture of #arketamine and #esketamine. Preclinical data and one open-label human trial suggest arketamine might exert a more potent and longer-lasting #antidepressant effect with fewer side effects. However, arketamine was not superior to #placebo for #TRD in our study.

    doi.org/10.1016/j.jad.2023.02.

    #Psychiatry #ClinicalTrials #Fediscience #PsychMastodon

  5. Excited to share our pioneer pilot crossover #RCT testing arketamine for treatment-resistant #depression (TRD). Racemic #ketamine is a mixture of #arketamine and #esketamine. Preclinical data and one open-label human trial suggest arketamine might exert a more potent and longer-lasting #antidepressant effect with fewer side effects. However, arketamine was not superior to #placebo for #TRD in our study.

    doi.org/10.1016/j.jad.2023.02.

    #Psychiatry #ClinicalTrials #Fediscience #PsychMastodon