#mammalian — Public Fediverse posts

Variable #transmission efficiency of #mammalian origin #HPAI D1.1 #H5N1 strains in #ferrets, https://etidiohnew.blogspot.com/2026/05/variable-transmission-efficiency-of.html

#Genetic and #biological characterization of a #duck-origin clade 2.3.4.4b #H5N6 avian #influenza virus reveals partial #mammalian #adaptation, https://etidiohnew.blogspot.com/2026/04/genetic-and-biological-characterization.html

#Genetic and #biological characterization of a #duck-origin clade 2.3.4.4b #H5N6 avian #influenza virus reveals partial #mammalian #adaptation, https://etidiohnew.blogspot.com/2026/04/genetic-and-biological-characterization.html

#Genetic and #biological characterization of a #duck-origin clade 2.3.4.4b #H5N6 avian #influenza virus reveals partial #mammalian #adaptation, https://etidiohnew.blogspot.com/2026/04/genetic-and-biological-characterization.html

#Genetic and #biological characterization of a #duck-origin clade 2.3.4.4b #H5N6 avian #influenza virus reveals partial #mammalian #adaptation, https://etidiohnew.blogspot.com/2026/04/genetic-and-biological-characterization.html

#Genetic and #biological characterization of a #duck-origin clade 2.3.4.4b #H5N6 avian #influenza virus reveals partial #mammalian #adaptation, https://etidiohnew.blogspot.com/2026/04/genetic-and-biological-characterization.html

Cytokines Market in Poland | Report – IndexBox https://www.byteseu.com/1918811/ #BiomarkerDiscoveryAndValidation #BiopharmaMarketReport #CellCultureAndStemCellExpansion #Cytokines #forecast #HighThroughputProteinPurification #ImmunologyAndInflammationResearch #LyophilizationAndStabilization #mammalian #MarketAnalysis #MultiplexImmunoassayPlatforms #Poland #RecombinantProteinExpressionSystems(EColi #TherapeuticDevelopmentForAutoimmuneDiseasesAndCancer #Yeast

https://www.europesays.com/uk/870718/ Cytokines Market in France | Report – IndexBox #BiomarkerDiscoveryAndValidation #BiopharmaMarketReport #CellCultureAndStemCellExpansion #Cytokines #EU #Europe #Forecast #France #HighThroughputProteinPurification #ImmunologyAndInflammationResearch #LyophilizationAndStabilization #mammalian #MarketAnalysis #MultiplexImmunoassayPlatforms #RecombinantProteinExpressionSystems(EColi #TherapeuticDevelopmentForAutoimmuneDiseasesAndCancer #yeast

Cytokines Market in France | Report – IndexBox

This repor…
#France #FR #Europe #EU #Biomarkerdiscoveryandvalidation #biopharmamarketreport #Cellcultureandstemcellexpansion #Cytokines #forecast #High-throughputproteinpurification #Immunologyandinflammationresearch #Lyophilizationandstabilization #mammalian #marketanalysis #Multipleximmunoassayplatforms #Recombinantproteinexpressionsystems(E.coli #Therapeuticdevelopmentforautoimmunediseasesandcancer #yeast)
https://www.europesays.com/france/2405/

Evolutionary #lineage and #host origin influence #virulence and #mammalian adaptation of #H7N9 avian #influenza viruses, https://etidiohnew.blogspot.com/2026/02/evolutionary-lineage-and-host-origin.html

#Genomic #features associated with sustained #mammalian #transmission of avian #influenza A viruses, https://etidiohnew.blogspot.com/2026/01/genomic-features-associated-with.html

''Of the nine D1.1 #infections in #humans, three viruses acquired #PB2 #mammalian #adaptations: D701N in A/Nevada/10/2025 and E627K in A/Wyoming/01/2025 and A/British Columbia/PHL-2032/2024''

Emergence of #mammalian-adaptive #PB2 #mutations enhances #polymerase activity and #pathogenicity of #cattle-derived #H5N1 #influenza A virus, https://etidiohnew.blogspot.com/2025/12/emergence-of-mammalian-adaptive-pb2.html

Distinctive viral #genome #signatures are linked to repeated #mammalian #spillovers of #H5N1 in North #America, https://etidiohnew.blogspot.com/2025/12/distinctive-viral-genome-signatures-are.html

Distinctive viral #genome #signatures are linked to repeated #mammalian #spillovers of #H5N1 in North #America, https://etidiohnew.blogspot.com/2025/12/distinctive-viral-genome-signatures-are.html

Distinctive viral #genome #signatures are linked to repeated #mammalian #spillovers of #H5N1 in North #America, https://etidiohnew.blogspot.com/2025/12/distinctive-viral-genome-signatures-are.html

Distinctive viral #genome #signatures are linked to repeated #mammalian #spillovers of #H5N1 in North #America, https://etidiohnew.blogspot.com/2025/12/distinctive-viral-genome-signatures-are.html

Distinctive viral #genome #signatures are linked to repeated #mammalian #spillovers of #H5N1 in North #America, https://etidiohnew.blogspot.com/2025/12/distinctive-viral-genome-signatures-are.html

An evolutionary approach to identify #mammalian adaptive #mutations in the avian #influenza #polymerase complex, https://etidiohnew.blogspot.com/2025/10/an-evolutionary-approach-to-identify.html

Cross-Species #Transmission #Risks of a #Quail-Origin #H7N9 #Influenza Virus from #China Between Avian and #Mammalian Hosts, https://etidiohnew.blogspot.com/2025/10/cross-species-transmission-risks-of.html

The #hemagglutinin proteins of clades 1 and 2.3.4.4b #H5N1 highly pathogenic avian #influenza viruses exhibit comparable attachment patterns to avian and #mammalian #tissues, https://etidiohnew.blogspot.com/2025/09/the-hemagglutinin-proteins-of-clades-1.html

The #hemagglutinin proteins of clades 1 and 2.3.4.4b #H5N1 highly pathogenic avian #influenza viruses exhibit comparable attachment patterns to avian and #mammalian #tissues, https://etidiohnew.blogspot.com/2025/09/the-hemagglutinin-proteins-of-clades-1.html

The #hemagglutinin proteins of clades 1 and 2.3.4.4b #H5N1 highly pathogenic avian #influenza viruses exhibit comparable attachment patterns to avian and #mammalian #tissues, https://etidiohnew.blogspot.com/2025/09/the-hemagglutinin-proteins-of-clades-1.html

The #hemagglutinin proteins of clades 1 and 2.3.4.4b #H5N1 highly pathogenic avian #influenza viruses exhibit comparable attachment patterns to avian and #mammalian #tissues, https://etidiohnew.blogspot.com/2025/09/the-hemagglutinin-proteins-of-clades-1.html

The #hemagglutinin proteins of clades 1 and 2.3.4.4b #H5N1 highly pathogenic avian #influenza viruses exhibit comparable attachment patterns to avian and #mammalian #tissues, https://etidiohnew.blogspot.com/2025/09/the-hemagglutinin-proteins-of-clades-1.html

#Inflammatory, transcriptomic, and #cell fate responses underlying the #mammalian #transmission of avian #influenza viruses, https://etidiohnew.blogspot.com/2025/08/inflammatory-transcriptomic-and-cell.html

E627V #mutation in #PB2 protein promotes the #mammalian #adaptation of novel #H10N3 avian #influenza virus, https://etidiohnew.blogspot.com/2025/06/e627v-mutation-in-pb2-protein-promotes.html

Progressive #Adaptation of Subtype #H6N1 Avian #Influenza Virus in #Taiwan Enhances #Mammalian #Infectivity, Pathogenicity, and #Transmissibility, https://etidiohnew.blogspot.com/2025/05/progressive-adaptation-of-subtype-h6n1.html

Progressive #Adaptation of Subtype #H6N1 Avian #Influenza Virus in #Taiwan Enhances #Mammalian #Infectivity, Pathogenicity, and #Transmissibility, https://etidiohnew.blogspot.com/2025/05/progressive-adaptation-of-subtype-h6n1.html

Progressive #Adaptation of Subtype #H6N1 Avian #Influenza Virus in #Taiwan Enhances #Mammalian #Infectivity, Pathogenicity, and #Transmissibility, https://etidiohnew.blogspot.com/2025/05/progressive-adaptation-of-subtype-h6n1.html

Progressive #Adaptation of Subtype #H6N1 Avian #Influenza Virus in #Taiwan Enhances #Mammalian #Infectivity, Pathogenicity, and #Transmissibility, https://etidiohnew.blogspot.com/2025/05/progressive-adaptation-of-subtype-h6n1.html

Progressive #Adaptation of Subtype #H6N1 Avian #Influenza Virus in #Taiwan Enhances #Mammalian #Infectivity, Pathogenicity, and #Transmissibility, https://etidiohnew.blogspot.com/2025/05/progressive-adaptation-of-subtype-h6n1.html

Molecular and ecological #determinants of #mammalian #adaptability in avian #influenza virus, https://etidiohnew.blogspot.com/2025/04/molecular-and-ecological-determinants.html

 
#Apes point out hidden treats only when #humans are #unaware of their #location.
❛❛ It's a #sign of a #cognitive ability called #Theory of #Mind. ❜❜

🔗 https://www.youtube.com/watch?v=kPD9jqXEv7Y 2025 Feb 04
🔗 https://www.SmithsonianMag.com/smart-news/when-bonobos-know-what-you-dont-theyll-tell-you-its-a-sign-of-a-cognitive-ability-called-theory-of-mind-180985991/ 2025 Feb 05
🔗 https://en.Wikipedia.org/wiki/Theory_of_mind … #TheoryOfMind

#Community #TimeTravel #Research #primates #mammalian #intelligence #interspecies #communitication #psychology #biology #science #Kronodon

'Ball and chain' mechanism inactivates key #mammalian #ion_channel, study finds

#potassium #BK_channels #calcium

https://phys.org/news/2025-03-ball-chain-mechanism-inactivates-key.html

@futurebird @falcennial @AlexanderVI

All advanced species have been eaten by Ants.
Hmm.

@cstross SF author near here wrote a couple of worlds/SF books in which the eventual winners are or are going to be the #eusocial species, of which #ants and suchlike seem to be examples.

Perhaps those winners would not bother to talk to us #mammalian species.

A low pathogenic avian #influenza A/Mallard/South Korea/KNU2019-34/2019 (#H1N1) virus has the potential to increase the #mammalian #pathogenicity, https://etidiohnew.blogspot.com/2024/12/a-low-pathogenic-avian-influenza.html

#Chicken ANP32A-independent #replication of highly pathogenic avian #influenza viruses potentially leads to #mammalian #adaptation-related amino acid substitutions in viral #PB2 and #PA proteins

Source: Journal of Virology, ABSTRACTAcidic nuclear phosphoprotein 32 family member A (ANP32A) is an important host factor that supports the efficient replication of avian influenza viruses (AIVs). To develop an antiviral strategy against Gs/Gd-lineage H5 highly pathogenic…

https://etidioh.wordpress.com/2024/11/21/chicken-anp32a-independent-replication-of-highly-pathogenic-avian-influenza-viruses-potentially-leads-to-mammalian-adaptation-related-amino-acid-substitutions-in-viral-pb2-and-pa-proteins/

An emerging #PB2-627 #polymorphism increases #pandemic #potential of avian #influenza virus by breaking through ANP32 host restriction in #mammalian & avian hosts, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.07.03.601996v4

by screening the global PB2 seq., we discovered a new independent cluster with PB2-627V emerged in the '10s, which is prevalent in various avian, mammalian, & human isolates of AIVs, including #H9N2, #H7N9, #H3N8, 2.3.4.4b #H5N1, and other subtypes.

Decoding non- #human #mammalian adaptive #signatures of 2.3.4.4b #H5N1 to assess its human adaptive #potential, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.08.26.609722v1?rss=1

H5N1 infections in mammals across time showed a unique set of adaptations in 2.3.4.4b clade compared to previously circulating strains, especially acquisition of Q591 adaptation in #PB2 that enables human adaptation.

An emerging #PB2-627 #polymorphism increases the #pandemic #potential of avian #influenza virus by breaking through ANP32 #host #restriction in #mammalian and avian hosts, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.07.03.601996v3

...we discovered a new independent #cluster with PB2-627V emerged in the 2010s, which is prevalent in various avian, mammalian, and human isolates of AIVs, including #H9N2, #H7N9, #H3N8, 2.3.4.4b #H5N1, and other subtypes.

''It is noteworthy that crucial mutations associated with #mammalian #host #adaptation and enhanced #transmission, specifically residues 271A, 292 V, 591 K, 627 K/V/A, 701N, in PB2 (28, 30, 33-35), and 228S, along with the #virulence-increasing residue 66S in PB1-F2(46), were conspicuously absent in all #HPAI virus strains derived from dairy #cattle and #cats. ''

An emerging #PB2-627 #polymorphism increases the #pandemic #potential of avian #influenza virus by breaking through ANP32 #host restriction in #mammalian and avian #hosts, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.07.03.601996v1?rss=1

The PB2-627V polymorphism has been found in birds, humans, and mammals worldwide across more than ten AIV #subtypes. Given the escalating global spread of AIVs, it is crucial to closely monitor influenza viruses carrying PB2-627V to prevent a pandemic.

#PB2 residue 473 contributes to the #mammalian #virulence of #H7N9 avian #influenza virus by modulating viral #polymerase activity via ANP32A, J Virol.: https://doi.org/10.1128/jvi.01944-23

-- In this study, we identified PB2 residue 473 as a new determinant of mouse virulence and mammalian #adaptation of the viral polymerase of the H7N9 virus and its non-pathogenic #H9N2 counterparts.

Detection of clade 2.3.4.4 highly pathogenic avian #influenza #H5 viruses in healthy wild #birds in the Hadeji-Nguru #wetland, #Nigeria 2022, https://onlinelibrary.wiley.com/doi/10.1111/irv.13254

-- Whole-genome characterization of the viruses reveals the presence of #mammalian adaptive #marker #E627K in two Afro-tropical resident aquatic #ducks. This has zoonotic potential.

The #mammalian #nose is a work of evolutionary art. Its millions of #nerve #cells, each tailored with just one of thousands of specific odor-chemical receptors encoded in the #genome, can collectively distinguish a trillion distinct #scents.
#Biology #Chemistry #Neuroscience #sflorg
https://www.sflorg.com/2023/12/bio12202303.html

The #neuropathogenesis of highly pathogenic #avian #influenza #H5Nx viruses in #mammalian species including #humans, Trends Neurosci., https://doi.org/10.1016/j.tins.2023.08.002 #epizootic #panzootic #zoonoses #EIDs #research #pandemic #pathology

Large-scale across species #transcriptomic analysis identifies genetic selection signatures associated with #longevity in mammals

Organ-specific expression patterns of #methionine restriction and translation fidelity genes correlate with longevity in 103 #mammalian species

https://www.embopress.org/doi/full/10.15252/embj.2022112740

What fine-tunes #mammalian brain connectivity during #development?
Urtė Neniškytė, Cornelius Gross et al identify #Xkr8 #phospholipid #scramblase as responsible for #phosphatidylserine eat-me signal exposure and #axon pruning to prevent global hyperconnectivity
https://www.embopress.org/doi/10.15252/embj.2022111790

@christinebeeton imagine if that had been one of our wedge tailed #eagles. Another of our iconic #wildlife #species with females standing up to 42" tall. Huge #birds. Beautiful to see.

An Australian #farmer would have shot it and hung it on a fence.

Anyone ever heard the expression "a #kangaroo short in the top paddock"?

It means not all there. Something's missing in the DNA that makes Australian #fharmers personally responsible for the greatest #mammalian #extinctions on the planet. Ever.

Australian #agriculture is only ever about #killing things. Even #grain growers. Everything gets #killed, that can't directly become a dollar.