#h7n9 — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #h7n9, aggregated by home.social.
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#Autoantibodies against type I #interferons in patients with #zoonotic #H7N9 #influenza: an observational case–control study, https://etidiohnew.blogspot.com/2026/07/autoantibodies-against-type-i.html
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Prior #immunity to seasonal #influenza #H3N2 virus confers varying levels of cross - #protection against challenge with clade 2.3.4.4b #H5N1, #H7N9, or #H9N2 virus in a #ferret model, https://etidiohnew.blogspot.com/2026/04/prior-immunity-to-seasonal-influenza.html
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Evolutionary #lineage and #host origin influence #virulence and #mammalian adaptation of #H7N9 avian #influenza viruses, https://etidiohnew.blogspot.com/2026/02/evolutionary-lineage-and-host-origin.html
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#Hemagglutinin with a #polybasic #cleavage site confers high #virulence on #H7N9 avian #influenza viruses, https://etidiohnew.blogspot.com/2025/01/hemagglutinin-with-polybasic-cleavage.html
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#Aminoacid #mutations #PB1-V719M and #PA-N444D combined with #PB2-627K contribute to the #pathogenicity of #H7N9 in #mice, Vet Res.: https://veterinaryresearch.biomedcentral.com/articles/10.1186/s13567-024-01342-6
Overall, this study revealed that #virulence in H7N9 is a #polygenic trait and identified novel virulence-related residues (PB2-627K combined with PB1-719M and/or PA-444D) in viral ribonucleoprotein (vRNP) complexes.
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#PB2 residue 473 contributes to the #mammalian #virulence of #H7N9 avian #influenza virus by modulating viral #polymerase activity via ANP32A, J Virol.: https://doi.org/10.1128/jvi.01944-23
-- In this study, we identified PB2 residue 473 as a new determinant of mouse virulence and mammalian #adaptation of the viral polymerase of the H7N9 virus and its non-pathogenic #H9N2 counterparts.