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#h9n2 — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #h9n2, aggregated by home.social.

  1. Dissecting the role of the HA1-226 #leucine #residue in the #fitness and #airborne #transmission of an A(#H9N2) avian #influenza virus

    Source: Journal of Virology, ABSTRACTA better understanding of viral factors that contribute to influenza A virus (IAV) airborne transmission is crucial for pandemic preparedness. A limited capacity for airborne transmission was recently observed in a human A(H9N2) virus isolate (A/Anhui-Lujiang/39/2018, AL/39) that possesses a leucine…

    etidioh.wordpress.com/2024/11/

  2. #Genotypic & #phenotypic susceptibility of emerging avian #influenza A viruses to
    #NAIs & cap-dependent endonuclease #inhibitors, Antiviral Res.: sciencedirect.com/science/arti

    Frequencies of markers of resistance to antivirals were low among >20,000 avian influenza A viruses studied. #H5Nx, #H7Nx, & #H9N2 viruses were susceptible to sub-nanomolar concentrations of antivirals. NA-I222M, but not NA-S246N or NA-I222V, in H5N1 confers reduced inhibition by #oseltamivir.

  3. #Diversity of #genotypes & #pathogenicity of #H9N2 avian #influenza virus derived from #wildbird and domestic #poultry, Front Microbiol.: frontiersin.org/journals/micro

    Genotype S H9N2 demonstrated oropharyngeal shedding, while genotype A H9N2 exhibited cloacal shedding & high viral loads in the duodenum. Both strains caused significant pathological injuries, with genotype S inducing more severe damage to the thymus and spleen, while genotype A caused duodenal muscle layer rupture.