#synthetic-biology — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #synthetic-biology, aggregated by home.social.
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The living bandage is a cell-based delivery platform that utilizes encapsulated, engineered cells as on-site "factories" to secrete therapeutic signaling proteins directly into a wound over extended periods. It is designed to maintain therapeutic levels of tissue-regenerating molecules precisely where they are needed most.
#Bioengineering #SyntheticBiology #Immunology #sflorg
https://www.sflorg.com/2026/05/beng05272601.html -
#Newswire: StrainX Bioworks has raised $13 million in a round led by Prime Venture Partners and Leo Capital as it emerges from two years of stealth-mode development. The India-based synthetic biology and microbial fermentation company has built an integrated platform spanning strain engineering, fermentation, and product development, and has demonstrated operations at 10,000-liter scale.
#SyntheticBiology #Fermentation #Biotech #FoodIngredients #India
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We The Subjects — Plundering Health Data
When geneticist Jingyuan Fu heard that an artificial intelligence (AI) group in China had downloaded a large biomedical dataset her team built in Europe, she felt pride — and a jolt of unease. “We spent millions on that dataset,” says Fu, a professor of systems medicine at the University of Groningen in the Netherlands. “And the Chinese bought the whole thing for around €2,000.” In recent years, Fu’s group, like many others, has also begun using such data as feedstock for […]https://law-in-action.com/2026/05/19/we-the-subjects-plundering-your-health-data/
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Xenobots are microscopic, programmable biological machines constructed entirely from living cells without any genetic modification. Measuring less than a millimeter, they lack traditional mechanical parts and are entirely organic, biodegradable, and derived primarily from embryonic stem cells of the African clawed frog (Xenopus laevis).
#WhatIs #EvolutionaryBiology #DevelopmentalBiology #SyntheticBiology #ComputationalBiology #SoftRobotics
https://www.sflorg.com/2026/05/wi05172601.html -
Scientists have engineered synthetic organelles using tiny sponge-like particles to transport a team of six proteins into living cells, creating a nanoscale factory that produces therapeutic compounds directly inside the cell.
#Nanotechnology #Bioengineering #MaterialScience #SyntheticBiology #sflorg
https://www.sflorg.com/2026/05/nt05142601.html -
Colossal Biosciences Is Making Jurassic Park Look Like a Pitch Deck
Modern biotechnology labs are driving advances in gene editing and de-extinction researchDear Cherubs, Dallas has apparently decided extinction is just a product category. Colossal Biosciences is now a billionaire-level biotech spectacle, with the company saying its latest Series C brought total funding to $615 million and ABC News reporting a roster of celebrity backers that includes Tom Brady, Tiger Woods, Paris Hilton and Peter Jackson. Dallas Innovates also reported that the CIA’s venture arm, In-Q-Tel, invested in Colossal back in 2022.
The result is a company that sounds like it was brainstormed by a film studio, a venture fund and a very committed science teacher. Colossal says it is working on de-extinction projects tied to the woolly mammoth, dodo, thylacine and dire wolf, using gene editing, synthetic biology and related conservation tools. So no, this is not literally Jurassic Park; it is more like Jurassic Park after legal review and a lot of grant money.
THE TEA, BUT WITH MICROPIPETTES
In April, Reuters reported that Colossal announced three genetically engineered wolf pups and called them the world’s first successfully “de-extincted” animals, while outside experts were more cautious and described them as genetically modified gray wolves with added dire-wolf traits. ABC News said Colossal edited gray wolf cells at multiple sites and noted the two species are about 99.5% genetically identical, which is a very impressive number and also a reminder that biology is rude and complicated.
That is the key detail the movie version never pauses for: the company is not dusting off a frozen dinosaur and pressing play. It is using ancient DNA, gene editing and surrogate biology to create something that resembles an extinct species closely enough to trigger headlines, debates and a healthy amount of side-eye. The label “de-extincted” is doing a lot of heavy lifting here.
WHY THE MONEY FLOWS
The money makes more sense when you look at the technology stack. Dallas Innovates reported that In-Q-Tel said its interest in Colossal was “less about the mammoths and more about the capability,” while Colossal’s own materials say the work could scale CRISPR, synthetic biology, artificial wombs and genomic preservation platforms. In other words, the extinct-animal angle is the headline; the platform is the business.
Colossal has also built a pop-culture-friendly halo around the science. Its advisory board page lists Tom Brady and George R.R. Martin among its cultural advisors, which is exactly the kind of sentence that makes the internet stop scrolling for a second. That is the trick here: make de-extinction feel part science, part blockbuster, part meme, and suddenly the cap table looks almost inevitable.
The hot take is simple: this is not a cartoonish clone factory, and it is not pure hype either. It is a very expensive attempt to push gene editing, cloning-adjacent methods and reproductive tech into territory that could one day matter for conservation as much as spectacle. The dinosaurs are still fiction, but the lab bills are extremely real.
Sources list
The Thisclaimer logo blends a classic warning symbol with a brain icon to represent critical thinking, curiosity, and thoughtful disclaimers. #animals #biotechnology #cia #colossalBiosciences #crispr #deExtinction #direWolf #geneEditing #inQTel #nature #news #science #syntheticBiology #texasStartup
ABC News — https://abcnews.go.com/US/dire-wolf-revived-biotech-companys-de-extinction-process/story?id=120558562
Reuters — https://www.reuters.com/science/us-company-resurrects-extinct-dire-wolf-or-some-version-it-2025-04-08/
Dallas Innovates — https://dallasinnovates.com/mammoth-interest-the-cia-invests-in-dallas-based-colossal-biosciences/
Colossal Biosciences — https://colossal.com/colossal-secures-200m-to-accelerate-de-extinction-and-genomic-innovation/
Colossal Biosciences — https://colossal.com/advisors/
Wikimedia Commons (Laboratory.jpg) — https://commons.wikimedia.org/wiki/File:Laboratory.jpg -
Silk-amyloid-mussel (SAM) protein hybrids are bioengineered materials produced by genetically modified microbes that serve as a fully recyclable, biodegradable alternative to synthetic textiles.
#SyntheticBiology #MaterialScience #Engineering #Environmental #sflorg
https://www.sflorg.com/2026/05/sybi05102601.html -
Senior Scientist - Molecular & Synthetic Biology
En Carta DiagnosticsJoin us as a Senior Scientist - Molecular & Synthetic Biology in beautiful Paris, France!
See the full job description on jobRxiv: https://jobrxiv.org/job/en-carta-diagnostics-27778-senior-scientist-molecular-synthetic-biology/
#molecularbiology #syntheticbiology #ScienceJobs #hiring #research
https://jobrxiv.org/job/en-carta-diagnostics-27778-senior-scientist-molecular-synthetic-biology/?fsp_sid=11897 -
The cytoplasmic abundant heat-soluble protein (CAHS12), naturally found in resilient microscopic tardigrades, can be utilized to preserve the structural integrity and biological function of synthetic cells during extreme dehydration. By replicating this natural survival mechanism, scientists can dry out and successfully rehydrate biological materials without causing cellular death.
#SyntheticBiology #MolecularEngineering #Biotechnology #Biochemistry #sflorg
https://www.sflorg.com/2026/05/sybi05062601.html -
🦠 Could we outsmart antibiotic resistance by turning bacteria against themselves?
🔗 Rational Targeting and gRNA Design for Enhancing Quorum Quenching in Pseudomonas aeruginosa PAO1. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0089
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#AntimicrobialResistance #AMR #CRISPR #GeneEditing #SyntheticBiology #SystemsBiology #Microbiology #Biotechnology #DrugResistance #QuorumSensing #Biofilms #Genomics
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When a gene is transcribed, it creates physical ripples along the DNA strand that can either activate or suppress neighboring genes. The physical ordering and arrangement of these genes, known as "gene syntax," directly dictates how their structural interactions couple their expression.
#SyntheticBiology #Biophysics #Genetics #ChemicalEngineering #sflorg
https://www.sflorg.com/2026/04/sybi04302601.html -
Synthetic biology is a multidisciplinary area of research that involves the design and construction of novel biological parts, devices, and systems, as well as the re-design of existing, natural biological systems for useful purposes. Its primary goal is to apply rigorous engineering principles to biology.
#SyntheticBiology #Biology #sflorg
https://www.sflorg.com/2026/04/cat04292601.html -
SMART (Single-Molecule Assay on Ribonucleic acid by Translated product) is an advanced in vitro selection platform designed to accelerate directed enzyme evolution. It significantly reduces the time and cost required to identify superior enzyme variants by tracking them at the single-molecule level.
#SyntheticBiology #MolecularBiology #Biochemistry #Biotechnology #sflorg
https://www.sflorg.com/2026/04/sybi04282601.html -
If you could build a synthetic plant-soil ecosystem from scratch for use on another planet (ignore if this makes sense or not), would it have mycorrhiza?
Explain why or why not... 😀
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Oh my holy rabbit. 300 chars on #BlueSky are so short but lets look maybe it will trigger someone there #Palantir & #KarpManifesto are boring. #BioHacking #SyntheticBiology is the future. https://floof.sbs#09 https://floof.sbs#12 multi-layered bio-cipher to hide messages in DNA using Gaussian bell curves, prime numbers, hydrogen-bond checksums & wobble positions of the code sun. Untraceable for any #LLM. #BioIT
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Epigenome regulators are specialized proteins bound to DNA that control gene expression not merely as simple on/off switches, but by producing distinct, uniquely patterned behaviors and expression dynamics for specific genes.
#Epigenetics #MolecularBiology #SyntheticBiology #CellularEngineering #sflorg
https://www.sflorg.com/2026/04/epig04202601.html -
🧬 // Is it a message or not (Where is Schrödingers cat Director´s Cut)
https://floof.sbs/#12
#DNA #Genetics #SyntheticBiology -
If we wanted to put together an artificial ecosystem to maximize one function (let’s say carbon storage), how would we do it?
This is interesting to think about…
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🧬 // Steganographic multi-layered bio-cipher. (Biopunk meets Geopunk Director’s Cut)
„It's a storage format, not just an acid“.
#BioHacking #Biopunk #BioSteganography #Cryptography #Cyberpunk #CyberSecurity #DNA #DNAStorage #Genetics #InfoSec #OpenScience #Science #SyntheticBiology
https://floof.sbs/#09 -
The sheer scale of what synthetic biology aims to achieve can often feel indistinguishable from science fiction. We are actively learning to speak the fundamental language of life, not merely to read its ancient history, but to actively write its future.
#SyntheticBiology #MolecularBiology #ComputationalBiology #Genetics #ArtificialIntelligence #sflorg
https://www.sflorg.com/2026/04/wi04042601.html -
#DNA polymerases—the microscopic biological machines responsible for replicating DNA—possess an innate capability to synthesize entirely new, highly complex, and extensive DNA sequences from scratch without utilizing an existing template.
#EngineeringBiology #MolecularBiology #SyntheticBiology #Biotechnology #sflorg
https://www.sflorg.com/2026/04/bio04012601.html -
🦠 Are microbes evolving faster than our ability to industrialize them?
🔗 Exploring Genome-Wide Mutation Dynamics and Bacterial Cellulose Impairment in Komagataeibacter intermedius Cultivated Under Agitation Stress. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0009
📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#SyntheticBiology #Sustainability #Biomaterials #Microbiology #IndustrialBiotechnology #MetabolicEngineering #Genomics #Phenomics
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A novel, environmentally sustainable biomanufacturing process that utilizes genetically engineered yeast to produce oxalic acid, which is subsequently used to extract and purify free rare-earth elements (REEs) from low-grade ore.
#SyntheticBiology #Chemistry #BiomolecularEngineering #MaterialsScience #Environmental #sflorg
https://www.sflorg.com/2026/03/beng03162601.html -
This toot is for people who are enjoying the #Oscars and cheering for #AcademyAwards won by the movie “#Frankenstein.”
As an added bonus for #science in #fiction enthusiasts, you’ll learn how the novelist Mary Shelley was inspired - and horrified - by advances in synthetic and electro-#chemistry 200 years ago! www.corpse.org/index.php?option=com_content&task=view&id=312&Itemid=57
#SyntheticBiology is fiction no more.
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#Extremophiles that can digest #radiation ☢️ and toxicities are already used to clean up everything from oil spills to the fallout of radioactive sites.
This means we could #engineer microbes that are resistant to freezing ❄️ temperatures and high levels of radiation.
Given that #microbes 🦠 helped make Earth habitable, we could use synthetic #biology to engineer microbes to speed up a similar process for #Mars 🔴 https://theconversation.com/how-to-engineer-microbes-to-enable-us-to-live-on-mars-253456
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Researchers engineered a novel DNA polymerase, designated C28, that efficiently synthesizes #RNA with high fidelity and speed, a capability that natural DNA polymerases are biologically designed to reject.
#Biochemistry #Pharmaceutical #Biomedical #SyntheticBiology #sflorg
https://www.sflorg.com/2026/02/bchm02102601.html -
"Using synthetic biology strategies, we engineered microbial cells to continuously produce olefin substrates and ene-reductase while regenerating cofactors directly from glucose. By externally supplying radical precursors or introducing synthetic pathways for their in situ production, we enabled fermentation-based microbial photobiosynthesis"
