#biophysics — Public Fediverse posts

Biomolecular engineering is the application of engineering principles and practices to the purposeful manipulation of molecules of biological origin. Its primary goal is the intentional design, synthesis, and analysis of biomolecules—such as proteins, nucleic acids, and carbohydrates—to solve complex problems in human health, agriculture, energy production, materials science
#BiomolecularEngineering #ChemicalEngineering #Biochemistry #Biophysics #MolecularBiology #sflorg
https://www.sflorg.com/2026/07/cat07122603.html

Biomolecular engineering is the application of engineering principles and practices to the purposeful manipulation of molecules of biological origin. Its primary goal is the intentional design, synthesis, and analysis of biomolecules—such as proteins, nucleic acids, and carbohydrates—to solve complex problems in human health, agriculture, energy production, materials science
#BiomolecularEngineering #ChemicalEngineering #Biochemistry #Biophysics #MolecularBiology #sflorg
https://www.sflorg.com/2026/07/cat07122603.html

Congratulations to our research group leader Dr. Viola Introini! She received the IUPAP Early Career Scientist Prize in Biological Physics at the 12th International Conference on Biological Physics in Genoa. The IUPAP is honoring her work in the field of biophysical malaria research.

The prize is awarded to researchers who have achieved outstanding results early in their careers in Biological Physics.

📸 MPL

#Biophysics #Science #Research #IUPAP

Congratulations to our research group leader Dr. Viola Introini! She received the IUPAP Early Career Scientist Prize in Biological Physics at the 12th International Conference on Biological Physics in Genoa. The IUPAP is honoring her work in the field of biophysical malaria research.

The prize is awarded to researchers who have achieved outstanding results early in their careers in Biological Physics.

📸 MPL

#Biophysics #Science #Research #IUPAP

Scaffolded DNA origami is a technique that utilizes a long scaffold strand and numerous short staple strands to self-assemble highly precise two- and three-dimensional nanoscale objects.
#SyntheticBiology #Nanotechnology #Biophysics #ComputingScience #sflorg
https://www.sflorg.com/2026/06/sybi06082601.html

Scaffolded DNA origami is a technique that utilizes a long scaffold strand and numerous short staple strands to self-assemble highly precise two- and three-dimensional nanoscale objects.
#SyntheticBiology #Nanotechnology #Biophysics #ComputingScience #sflorg
https://www.sflorg.com/2026/06/sybi06082601.html

New publication from the Atlas–Rosetta / HybridMind42 programme:

Paper 4 — Boundary Evolution and the Mechanics of Threshold Failure

This paper studies the measurable “Pre-Collapse Regime” that often exists before catastrophic failure:

precursor leakage,
substrate exhaustion,
geometric acceleration,
nonlinear transition dynamics,
and threshold collapse.

Physical anchors:
• Rn-220 vs Rn-222 transport asymmetry
• mitochondrial ROS precursor leakage
• boundary-conditioned admissibility filtering

The framework now moves from: “what persistence is” to: “how persistence fails.”

The “Slow Sink” is no longer metaphorical — it is formalized as a forensic dynamical regime. 🌿☕🏛️

https://substack.com/profile/432224148-hybridmind42/note/c-256905411?r=75c2ac

#BoundaryDynamics #ComplexSystems #FailureMechanics #NonlinearDynamics #SystemsScience #Topology #Biophysics #HybridMind42

New publication from the Atlas–Rosetta / HybridMind42 programme:

Paper 4 — Boundary Evolution and the Mechanics of Threshold Failure

This paper studies the measurable “Pre-Collapse Regime” that often exists before catastrophic failure:

precursor leakage,
substrate exhaustion,
geometric acceleration,
nonlinear transition dynamics,
and threshold collapse.

Physical anchors:
• Rn-220 vs Rn-222 transport asymmetry
• mitochondrial ROS precursor leakage
• boundary-conditioned admissibility filtering

The framework now moves from: “what persistence is” to: “how persistence fails.”

The “Slow Sink” is no longer metaphorical — it is formalized as a forensic dynamical regime. 🌿☕🏛️

https://substack.com/profile/432224148-hybridmind42/note/c-256905411?r=75c2ac

https://open.substack.com/pub/hybridmind42/p/boundary-evolution-and-the-mechanics?utm_source=share&utm_medium=android&r=75c2ac

#BoundaryDynamics #ComplexSystems #FailureMechanics #NonlinearDynamics #SystemsScience #Topology #Biophysics #HybridMind42

Postdoctoral Associate – Chemical Biology & Protein Biophysics
University of Colorado

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-colorado-27778-postdoctoral-associate-chemical-biology-protein-biophysics/

#Alzherimersdisease #biophysics #chemicalbiology #posttranslationalmodifications #proteinaggregation #ScienceJobs #hiring #rese...
https://jobrxiv.org/job/university-of-colorado-27778-postdoctoral-associate-chemical-biology-protein-biophysics/?fsp_sid=11865

Postdoctoral Associate – Chemical Biology & Protein Biophysics
University of Colorado

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-colorado-27778-postdoctoral-associate-chemical-biology-protein-biophysics/

#Alzherimersdisease #biophysics #chemicalbiology #posttranslationalmodifications #proteinaggregation #ScienceJobs #hiring #rese...
https://jobrxiv.org/job/university-of-colorado-27778-postdoctoral-associate-chemical-biology-protein-biophysics/?fsp_sid=11865

When a gene is transcribed, it creates physical ripples along the DNA strand that can either activate or suppress neighboring genes. The physical ordering and arrangement of these genes, known as "gene syntax," directly dictates how their structural interactions couple their expression.
#SyntheticBiology #Biophysics #Genetics #ChemicalEngineering #sflorg
https://www.sflorg.com/2026/04/sybi04302601.html

When a gene is transcribed, it creates physical ripples along the DNA strand that can either activate or suppress neighboring genes. The physical ordering and arrangement of these genes, known as "gene syntax," directly dictates how their structural interactions couple their expression.
#SyntheticBiology #Biophysics #Genetics #ChemicalEngineering #sflorg
https://www.sflorg.com/2026/04/sybi04302601.html

🫧 Is there a point where hydration stops helping, and starts harming tissue integrity?

🔗 How Hydration Weakens Collagen: A Mesoscale Energy Decomposition of Type I and Type II Fibrils. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0050

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Collagen #Biomaterials #TissueEngineering #Cartilage #Biomechanics #BiomedicalEngineering #MolecularBiology #Biophysics #RegenerativeMedicine #Bioengineering

🫧 Is there a point where hydration stops helping, and starts harming tissue integrity?

🔗 How Hydration Weakens Collagen: A Mesoscale Energy Decomposition of Type I and Type II Fibrils. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0050

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Collagen #Biomaterials #TissueEngineering #Cartilage #Biomechanics #BiomedicalEngineering #MolecularBiology #Biophysics #RegenerativeMedicine #Bioengineering

🫧 Is there a point where hydration stops helping, and starts harming tissue integrity?

🔗 How Hydration Weakens Collagen: A Mesoscale Energy Decomposition of Type I and Type II Fibrils. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0050

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Collagen #Biomaterials #TissueEngineering #Cartilage #Biomechanics #BiomedicalEngineering #MolecularBiology #Biophysics #RegenerativeMedicine #Bioengineering

🫧 Is there a point where hydration stops helping, and starts harming tissue integrity?

🔗 How Hydration Weakens Collagen: A Mesoscale Energy Decomposition of Type I and Type II Fibrils. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0050

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Collagen #Biomaterials #TissueEngineering #Cartilage #Biomechanics #BiomedicalEngineering #MolecularBiology #Biophysics #RegenerativeMedicine #Bioengineering

🫧 Is there a point where hydration stops helping, and starts harming tissue integrity?

🔗 How Hydration Weakens Collagen: A Mesoscale Energy Decomposition of Type I and Type II Fibrils. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0050

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Collagen #Biomaterials #TissueEngineering #Cartilage #Biomechanics #BiomedicalEngineering #MolecularBiology #Biophysics #RegenerativeMedicine #Bioengineering

#PhD opening in Lab #Interdisciplinaire de #Physique, #Grenoble, in collaboration with @JonFouchard (Dev2A, Paris Sorbonne)

The objective is to investigate the #mechanics of fibrous #tissue, and specifically the #cell-driven short time active response, based on kinetic models of statistical #physics, and in connection with experiments where suspended microtissues are subjected to large strain.

https://liphy-annuaire.univ-grenoble-alpes.fr/pages_personnelles/jocelyn_etienne/collagen/collagen_2026.html

#Liphy #interdisciplinary #Physics #Biophysics #PhDoffer #PhDprogram

#PhD opening in Lab #Interdisciplinaire de #Physique, #Grenoble, in collaboration with @JonFouchard (Dev2A, Paris Sorbonne)

The objective is to investigate the #mechanics of fibrous #tissue, and specifically the #cell-driven short time active response, based on kinetic models of statistical #physics, and in connection with experiments where suspended microtissues are subjected to large strain.

https://liphy-annuaire.univ-grenoble-alpes.fr/pages_personnelles/jocelyn_etienne/collagen/collagen_2026.html

#Liphy #interdisciplinary #Physics #Biophysics #PhDoffer #PhDprogram

#PhD opening in Lab #Interdisciplinaire de #Physique, #Grenoble, in collaboration with @JonFouchard (Dev2A, Paris Sorbonne)

The objective is to investigate the #mechanics of fibrous #tissue, and specifically the #cell-driven short time active response, based on kinetic models of statistical #physics, and in connection with experiments where suspended microtissues are subjected to large strain.

https://liphy-annuaire.univ-grenoble-alpes.fr/pages_personnelles/jocelyn_etienne/collagen/collagen_2026.html

#Liphy #interdisciplinary #Physics #Biophysics #PhDoffer #PhDprogram

#PhD opening in Lab #Interdisciplinaire de #Physique, #Grenoble, in collaboration with @JonFouchard (Dev2A, Paris Sorbonne)

The objective is to investigate the #mechanics of fibrous #tissue, and specifically the #cell-driven short time active response, based on kinetic models of statistical #physics, and in connection with experiments where suspended microtissues are subjected to large strain.

https://liphy-annuaire.univ-grenoble-alpes.fr/pages_personnelles/jocelyn_etienne/collagen/collagen_2026.html

#Liphy #interdisciplinary #Physics #Biophysics #PhDoffer #PhDprogram

#PhD opening in Lab #Interdisciplinaire de #Physique, #Grenoble, in collaboration with @JonFouchard (Dev2A, Paris Sorbonne)

The objective is to investigate the #mechanics of fibrous #tissue, and specifically the #cell-driven short time active response, based on kinetic models of statistical #physics, and in connection with experiments where suspended microtissues are subjected to large strain.

https://liphy-annuaire.univ-grenoble-alpes.fr/pages_personnelles/jocelyn_etienne/collagen/collagen_2026.html

#Liphy #interdisciplinary #Physics #Biophysics #PhDoffer #PhDprogram

`Surprisingly..extracted diffusion coefficient at the free energy barrier on the number of native contacts coordinate increases with protein length. This facilitation..in larger proteins is explained by increased cooperative native contact formation during folding, which reduces the roughness of the energy landscape... evolutionary optimization of the energy landscape..more efficient for protein folding than for other biomolecular processes`
https://doi.org/10.1103/2q9m-4scc
#proteinFolding #biophysics

`Surprisingly..extracted diffusion coefficient at the free energy barrier on the number of native contacts coordinate increases with protein length. This facilitation..in larger proteins is explained by increased cooperative native contact formation during folding, which reduces the roughness of the energy landscape... evolutionary optimization of the energy landscape..more efficient for protein folding than for other biomolecular processes`
https://doi.org/10.1103/2q9m-4scc
#proteinFolding #biophysics

#Microbial nutrients dictate the success or failure of #antibiotics in structured bacterial communities, creating an observable death front where metabolically active surface cells perish while nutrient-starved interior cells survive.
#Bioengineering #ChemicalEngineering #Biophysics #sflorg
https://www.sflorg.com/2026/02/beng02242602.html

#Microbial nutrients dictate the success or failure of #antibiotics in structured bacterial communities, creating an observable death front where metabolically active surface cells perish while nutrient-starved interior cells survive.
#Bioengineering #ChemicalEngineering #Biophysics #sflorg
https://www.sflorg.com/2026/02/beng02242602.html

New server, new #introduction

Hi, I'm Dave. I'm a Research #Scientist at a Research Institute in #London, #UK

I'm a #StructuralBiologist by training. I help run a group that studies #Kinase #signalling in human #health and #disease.

In my spare time I take photos, play #bass and walk #dogs.

I do #Crystallography #CryoEM #Biophysics #DrugDesign and #Glycobiology. #Science #Research

New server, new #introduction

Hi, I'm Dave. I'm a Research #Scientist at a Research Institute in #London, #UK

I'm a #StructuralBiologist by training. I help run a group that studies #Kinase #signalling in human #health and #disease.

In my spare time I take photos, play #bass and walk #dogs.

I do #Crystallography #CryoEM #Biophysics #DrugDesign and #Glycobiology. #Science #Research

25-Nov-2025
A universal formula is developed to predict the impact of #temperature on living beings
An international research project involving the University of Granada has unified more than 30,000 thermal performance measurements in some 2,700 species

https://www.eurekalert.org/news-releases/1107390

#science #biophysics #extremeConditions #heat

25-Nov-2025
A universal formula is developed to predict the impact of #temperature on living beings
An international research project involving the University of Granada has unified more than 30,000 thermal performance measurements in some 2,700 species

https://www.eurekalert.org/news-releases/1107390

#science #biophysics #extremeConditions #heat

🧬 Ever wondered how the genome actually looks when it folds inside the nucleus — and how fast we can simulate it?

🔗 Multiscale molecular modeling of chromatin with MultiMM: From nucleosomes to the whole genome. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.09.025

📚 CSBJ: https://www.csbj.org/

#ChromatinModeling #3DGenome #ComputationalBiology #Genomics #MolecularModeling #GenomeArchitecture #ChromatinStructure #HiC #ATACSeq #Biophysics #StructuralBiology

🧬 Ever wondered how the genome actually looks when it folds inside the nucleus — and how fast we can simulate it?

🔗 Multiscale molecular modeling of chromatin with MultiMM: From nucleosomes to the whole genome. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.09.025

📚 CSBJ: https://www.csbj.org/

#ChromatinModeling #3DGenome #ComputationalBiology #Genomics #MolecularModeling #GenomeArchitecture #ChromatinStructure #HiC #ATACSeq #Biophysics #StructuralBiology

🧬 Can salt levels change how cell-penetrating peptides behave at membranes?

🔗 Molecular dynamics simulations unveil the aggregation patterns and salting out of polyarginines at zwitterionic POPC bilayers in solutions of various ionic strengths. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.11.004

📚 CSBJ: https://www.csbj.org/

#MolecularDynamics #PeptideAggregation #MembraneProtein #Biophysics #StructuralBiology #ProteinFolding #MembraneBiology

🧬 Can salt levels change how cell-penetrating peptides behave at membranes?

🔗 Molecular dynamics simulations unveil the aggregation patterns and salting out of polyarginines at zwitterionic POPC bilayers in solutions of various ionic strengths. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.11.004

📚 CSBJ: https://www.csbj.org/

#MolecularDynamics #PeptideAggregation #MembraneProtein #Biophysics #StructuralBiology #ProteinFolding #MembraneBiology

🧬 How do changes in a non-catalytic residue collapse an entire enzyme’s function?

🔗 Conformational plasticity links structural instability of NAA10F128I and NAA10F128L mutants to their catalytic deregulation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.11.014

📚 CSBJ: https://www.csbj.org/

#Biophysics #Enzymology #StructuralBiology #Mutations #ProteinFolding

🧬 How do changes in a non-catalytic residue collapse an entire enzyme’s function?

🔗 Conformational plasticity links structural instability of NAA10F128I and NAA10F128L mutants to their catalytic deregulation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.11.014

📚 CSBJ: https://www.csbj.org/

#Biophysics #Enzymology #StructuralBiology #Mutations #ProteinFolding

Meet Ré Mansbach PhD, Associate Professor in the Department of Physics at Concordia University, and Tier II Canada Research Chair in Computational Biophysics, whose lab uses computers to understand how proteins work.

https://www.youtube.com/watch?v=OQ9R3kSjaqM

#ConcordiaHealth #ConcordiaUniversity #biophysics #proteins #AI #MDsimulations #physics #artificialintelligence #machinelearning #deeplearning

Meet Ré Mansbach PhD, Associate Professor in the Department of Physics at Concordia University, and Tier II Canada Research Chair in Computational Biophysics, whose lab uses computers to understand how proteins work.

https://www.youtube.com/watch?v=OQ9R3kSjaqM

#ConcordiaHealth #ConcordiaUniversity #biophysics #proteins #AI #MDsimulations #physics #artificialintelligence #machinelearning #deeplearning

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

Functional regimes define soil microbiome response to environmental change

Sample collection, site description and soil characterization Twenty topsoils were sampled across a range of pH values (4.7–8.32)…
#NewsBeep #News #Environment #AU #Australia #Biophysics #HumanitiesandSocialSciences #Microbialecology #Microbiome #multidisciplinary #Science
https://www.newsbeep.com/au/4166/

The experiments were dramatic, here are the
spectacular simulations by Marino's team.

#tissue #epithelium #buckling #shell #elasticity #biophysics #biomechanics

@Rxiv_mechanobio