#crisprcas9 — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #crisprcas9, aggregated by home.social.
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Molekulární sebevražedný terminátor zabíjející nádorové buňky. 👍
RE: https://libera.site/item/739c3ff1-48fb-541a-a44f-cd0e68a0844a
#Rakovina #CRISPRCAS9 -
#Extremophiles that can digest #radiation ☢️ and toxicities are already used to clean up everything from oil spills to the fallout of radioactive sites.
This means we could #engineer microbes that are resistant to freezing ❄️ temperatures and high levels of radiation.
Given that #microbes 🦠 helped make Earth habitable, we could use synthetic #biology to engineer microbes to speed up a similar process for #Mars 🔴 https://theconversation.com/how-to-engineer-microbes-to-enable-us-to-live-on-mars-253456
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#Extremophiles that can digest #radiation ☢️ and toxicities are already used to clean up everything from oil spills to the fallout of radioactive sites.
This means we could #engineer microbes that are resistant to freezing ❄️ temperatures and high levels of radiation.
Given that #microbes 🦠 helped make Earth habitable, we could use synthetic #biology to engineer microbes to speed up a similar process for #Mars 🔴 https://theconversation.com/how-to-engineer-microbes-to-enable-us-to-live-on-mars-253456
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🧬 CRISPR-Cas Fact:
CRISPR-Cas9 ist eine Genschere, die ursprünglich aus dem Immunsystem von Bakterien stammt – sie nutzen sie, um Viren gezielt zu erkennen und deren DNA zu zerschneiden. Heute wird diese Technik verwendet, um Gene präzise zu verändern, z. B. in der Medizin, Landwirtschaft und Forschung. -
🧬 CRISPR-Cas Fact:
CRISPR-Cas9 ist eine Genschere, die ursprünglich aus dem Immunsystem von Bakterien stammt – sie nutzen sie, um Viren gezielt zu erkennen und deren DNA zu zerschneiden. Heute wird diese Technik verwendet, um Gene präzise zu verändern, z. B. in der Medizin, Landwirtschaft und Forschung. -
🧬 CRISPR technology revolutionizes gene editing 🔬, enabling precise DNA modification for research, diagnostics, and future medical innovations 🚀.
#CRISPR #CRISPRCas9 #GeneEditing #Biotechnology #MolecularBiology #GeneticEngineering #LifeScienceStudents #ResearchInnovation #Bioinformatics #BioResire -
🧬 CRISPR technology revolutionizes gene editing 🔬, enabling precise DNA modification for research, diagnostics, and future medical innovations 🚀.
#CRISPR #CRISPRCas9 #GeneEditing #Biotechnology #MolecularBiology #GeneticEngineering #LifeScienceStudents #ResearchInnovation #Bioinformatics #BioResire -
Z toho se někteří opupínkují, ale já bych do toho hned šel. 😁
15 lidí s velmi vysokými hodnotami špatného cholesterolu podstoupilo dvouhodinovou infuzi s genovou terapií na vypnutí genu ANGPTL3. Potom měli i po měsících o 50% nižší cholesterol.
#^https://www.reuters.com/business/healthcare-pharmaceuticals/crispr-gene-therapy-slashes-bad-cholesterol-triglycerides-by-half-small-study-2025-11-08/
#GenováTerapie #CRISPRCAS9 -
[Перевод] CRISPR снова в строю! Генная терапия против холестерина прошла первое в мире клиническое испытание на людях
В первом в мире исследовании ученые применили разовое редактирование генома с помощью CRISPR. Цель – отключить ген, способствующий накоплению плохого холестерина. Благодаря чему удалось снизить уровни холестерина и триглицеридов у пациентов, которые не реагировали на стандартное лечение.
https://habr.com/ru/articles/965460/
#CRISPR #crisprcas9 #редактирование_генома #клинические_испытания #геном #биотех #биотехнологии #испытания_на_людях #холестерин #плохой_холестерин
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Neue Strategie gegen #Malaria: Mithilfe von #CRISPRCas9 haben Forscher:innen eine einzelne Aminosäure in Mücken genetisch so verändert, dass sie keine Malaria-Erreger mehr auf Menschen übertragen können. Wie genau das funktioniert, erklärt #TheScientist. https://www.the-scientist.com/a-single-genetic-tweak-stops-mosquitoes-from-spreading-malaria-73202
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Neue Strategie gegen #Malaria: Mithilfe von #CRISPRCas9 haben Forscher:innen eine einzelne Aminosäure in Mücken genetisch so verändert, dass sie keine Malaria-Erreger mehr auf Menschen übertragen können. Wie genau das funktioniert, erklärt #TheScientist. https://www.the-scientist.com/a-single-genetic-tweak-stops-mosquitoes-from-spreading-malaria-73202
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Fixing a Fatal Genetic Defect in Babies With a Bit of Genetic Modification https://hackaday.com/2025/05/27/fixing-a-fatal-genetic-defect-in-babies-with-a-bit-of-genetic-modification/ #HackadayColumns #CRISPRCaS9 #Science #ammonia #CRISPR #urea
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Fixing a Fatal Genetic Defect in Babies With a Bit of Genetic Modification https://hackaday.com/2025/05/27/fixing-a-fatal-genetic-defect-in-babies-with-a-bit-of-genetic-modification/ #HackadayColumns #CRISPRCaS9 #Science #ammonia #CRISPR #urea
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Fixing a Fatal Genetic Defect in Babies With a Bit of Genetic Modification - Genetic defects are exceedingly common, which is not surprising considering just h... - https://hackaday.com/2025/05/27/fixing-a-fatal-genetic-defect-in-babies-with-a-bit-of-genetic-modification/ #hackadaycolumns #crisprcas9 #science #ammonia #crispr #urea
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Fixing a Fatal Genetic Defect in Babies With a Bit of Genetic Modification - Genetic defects are exceedingly common, which is not surprising considering just h... - https://hackaday.com/2025/05/27/fixing-a-fatal-genetic-defect-in-babies-with-a-bit-of-genetic-modification/ #hackadaycolumns #crisprcas9 #science #ammonia #crispr #urea
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New paper in MBE by Pfalz et al - genetic variation at a near-cryptic QTL for defense metabolites in Arabidopsis is shaped by balancing selection and ectopic gene conversion among duplicated O-methyltransferase genes.
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New paper in MBE by Pfalz et al - genetic variation at a near-cryptic QTL for defense metabolites in Arabidopsis is shaped by balancing selection and ectopic gene conversion among duplicated O-methyltransferase genes.
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Молекулярные моторы: как химия создаёт нанороботов будущего
Молекулярные моторы: как химия создаёт нанороботов будущего (И почему Нобелевская премия 2016 года изменила правила игры) Введение: От молекул к машинам В 1827 году ботаник Роберт Броун наблюдал, как частицы пыльцы беспорядочно двигаются в воде. Сегодня мы не просто объяснили это явление — мы научились проектировать молекулы, которые движутся целенаправленно . Речь о молекулярных моторах — синтетических структурах, способных преобразовывать энергию в механическую работу. Это не фантастика: такие «наномашины» уже доставляют лекарства в клетки, сортируют молекулы и даже генерируют механическую силу. Что такое молекулярный мотор?
https://habr.com/ru/companies/inferit/articles/893254/
#сезон_будущее_здесь #молекулярные_механизмы #наноботы #нобелевская_премия #crisprcas9 #crispr #днкоригами
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Emmanuelle Charpentier is a French microbiologist, geneticist and biochemist. In 2020, she and Jennifer Doudna were awarded the Nobel Prize in Chemistry for their groundbreaking work on the CRISPR-Cas9 technology. This was the first science Nobel Prize ever won by two women only. To honour her great contributions to microbiology, genetics and biochemistry, DSMZ researchers named the strain Pseudonocardia charpentierae (DSM 45834) after her.
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Mañana estaré en Valencia, invitado por Andrés Moya FISABIO para participar junto a Chema Millán IISLaFe y Antonio Sánchez Amat UMU en este workshop donde hablaremos de las nuevas herramientas de edición genética, que amplian el campo, más allá de las #CRISPR y #CRISPRCas9
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Mañana estaré en Valencia, invitado por Andrés Moya FISABIO para participar junto a Chema Millán IISLaFe y Antonio Sánchez Amat UMU en este workshop donde hablaremos de las nuevas herramientas de edición genética, que amplian el campo, más allá de las #CRISPR y #CRISPRCas9
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💬 "Introducing heritable #rabies immunity into North American red fox populations 🦊 through gene drive represents a strategy to both battle rabies and adjust the #ecology of (sub)urban environments."
🔓 Research Idea: https://doi.org/10.3897/rio.10.e134189 .
#CRISPR #CRISPRCas9 #wildlife #publichealth #zoonosis #zoonotic
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💬 "Introducing heritable #rabies immunity into North American red fox populations 🦊 through gene drive represents a strategy to both battle rabies and adjust the #ecology of (sub)urban environments."
🔓 Research Idea: https://doi.org/10.3897/rio.10.e134189 .
#CRISPR #CRISPRCas9 #wildlife #publichealth #zoonosis #zoonotic
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Jennifer Doudna is an American biochemist and molecular biologist. In 2020, Doudna and Emmanuelle Charpentier were awarded the Nobel Prize in Chemistry for their groundbreaking work on the CRISPR-Cas9 gene editing technology. This was the first science Nobel Prize ever won by two women only. To honour her great contributions in biochemistry, genetics and microbiology, DSMZ researchers named the strain Streptomyces doudnae (DSM 41981) after her.
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CAR-T buňka je T lymfocyt, který je geneticky upraven(ano, CRISPR-Cas9) tak, aby napadal např. rakovinné buňky. Aby nenapadal tělo, resp. imunitní systém nelikvidoval CAR-T, musí se brát od pacienta, geneticky upravit, namnožit a pak vstříknout pacientovi. To je drahé jak prase.
Číňani vzali T lymfocyty od mladé zdravé ženy, geneticky upravili tak, aby byly neviditelné pro imunitní systém, pak geneticky upravili na hon zblblých B buněk, které vytvářejí autoprotilátky, a hle! Pacoši s těžkými autoimunními nemocemi jsou v remisi!
To je docela bomba... 💣
Human Progress wrote the following post Mon, 07 Oct 2024 20:54:00 +0200New Therapy Sends Autoimmune Diseases Into Remission
“One woman and two men with severe autoimmune conditions have gone into
remission after being treated with bioengineered and CRISPR-modified
immune cells. The three individuals from China are the first people with
autoimmune disorders to be treated with engineered immune cells created
from donor cells, rather than ones collected from their own bodies. This
advance […]
The post New Therapy Sends Autoimmune Diseases Into Remission appeared
first on Human Progress.
https://humanprogress.org/therapy-using-donor-cells-sends-autoimmune-diseases-into-remission/ View article View summary #^New Therapy Sends Autoimmune Diseases Into Remission
“One woman and two men with severe autoimmune conditions have gone into remission after being treated with bioengineered and CRISPR-modified immune cells. The three individuals from China are the first people with autoimmune disorders to be treated with engineered immune cells created from donor cells, rather than ones collected from their own bodies. This advance is the first step towards mass production of such therapies.
One of the recipients, Mr Gong, a 57-year-old man from Shanghai, has systemic sclerosis, which affects connective tissue and can result in skin stiffening and organ damage. He says that three days after receiving the therapy, he felt his skin loosen and he could start moving his fingers and opening his mouth again. Two weeks later, he returned to his office job. ‘I feel very good,’ he says, more than a year after receiving the treatment.”
From Nature.
The post New Therapy Sends Autoimmune Diseases Into Remission appeared first on Human Progress.
#CRISPRCAS9 #CAR-T -
Vyřazením proteinu Slc2a4 k mladistvému mozku?
Human Progress wrote the following post Fri, 04 Oct 2024 20:01:00 +0200CRISPR Helps Brain Stem Cells Regain Youth in Mice
“Clues to keeping the brain’s regenerative cells youthful and
energetic into old age have emerged by applying CRISPR gene editing to
mice. Age impedes the ability of the brain’s stem cells to churn out new
cells, but the study’s authors found that reducing the activity of a
particular gene rejuvenated these stem cells, allowing them […]
The post CRISPR Helps Brain Stem Cells Regain Youth in Mice appeared first
on Human Progress.
https://humanprogress.org/crispr-helps-brain-stem-cells-regain-youth-in-mice/ View article View summary #^CRISPR Helps Brain Stem Cells Regain Youth in Mice
“Clues to keeping the brain’s regenerative cells youthful and energetic into old age have emerged by applying CRISPR gene editing to mice.
Age impedes the ability of the brain’s stem cells to churn out new cells, but the study’s authors found that reducing the activity of a particular gene rejuvenated these stem cells, allowing them to proliferate and provide the brain with a supply of fresh neurons.
That gene regulates stem cells’ consumption of glucose, a sugar that is key to cellular metabolism. The results in mice fit well with an emerging picture from studies of postmortem human brains. These efforts, too, have found that age affects metabolism in the brain.”
From Nature.
The post CRISPR Helps Brain Stem Cells Regain Youth in Mice appeared first on Human Progress.
#Omlazování #CRISPRCAS9 -
Potential Cure For All of England’s Beta Thalassemia Patients Within Reach https://hackaday.com/2024/08/10/potential-cure-for-all-of-englands-beta-thalassemia-patients-within-reach/ #blooddisorders #MedicalHacks #gene-therapy #CRISPRCaS9 #Lifehacks #CRISPR #News
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Potential Cure For All of England’s Beta Thalassemia Patients Within Reach https://hackaday.com/2024/08/10/potential-cure-for-all-of-englands-beta-thalassemia-patients-within-reach/ #blooddisorders #MedicalHacks #gene-therapy #CRISPRCaS9 #Lifehacks #CRISPR #News
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Potential Cure For All of England’s Beta Thalassemia Patients Within Reach - Beta thalassemia and sickle cell are two red blood cell disorders which both come ... - https://hackaday.com/2024/08/10/potential-cure-for-all-of-englands-beta-thalassemia-patients-within-reach/ #blooddisorders #medicalhacks #gene-therapy #crisprcas9 #lifehacks #crispr #news
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Potential Cure For All of England’s Beta Thalassemia Patients Within Reach - Beta thalassemia and sickle cell are two red blood cell disorders which both come ... - https://hackaday.com/2024/08/10/potential-cure-for-all-of-englands-beta-thalassemia-patients-within-reach/ #blooddisorders #medicalhacks #gene-therapy #crisprcas9 #lifehacks #crispr #news
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Možnost editace větších kusů DNA, než CRISP-CAS9?
Sem s tím!
Human Progress wrote the following post Mon, 08 Jul 2024 17:10:00 +0200“Jumping Gene” Enzyme Edits Genomes without Breaking DNA
“A molecular oddity found in bacteria could hold the key to redesigning
genomes at will, allowing researchers to insert, delete or flip large
segments of DNA. The technique, described in three papers published this
month in Nature and Nature Communications, harnesses the natural ability
of mobile genetic sequences, called jumping genes, to insert themselves
into […]
The post “Jumping Gene” Enzyme Edits Genomes without Breaking DNA
appeared first on Human Progress.
https://humanprogress.org/oddball-jumping-gene-enzyme-edits-genomes-without-breaking-dna/ View article View summary #^“Jumping Gene” Enzyme Edits Genomes without Breaking DNA
“A molecular oddity found in bacteria could hold the key to redesigning genomes at will, allowing researchers to insert, delete or flip large segments of DNA.
The technique, described in three papers published this month in Nature and Nature Communications, harnesses the natural ability of mobile genetic sequences, called jumping genes, to insert themselves into genomes.
Guided by an RNA molecule called a ‘bridge’ RNA or ‘seekRNA’, the system has been shown to edit genes in a bacterium and in test-tube reactions, but it is still unclear whether it can be adapted to work in human cells. If it can, it could be revolutionary, owing to its small size and its ability to make genetic changes that are thousands of bases long — much larger than is practical with the CRISPR–Cas9 genome-editing system — without breaking DNA.”
From Nature.
The post “Jumping Gene” Enzyme Edits Genomes without Breaking DNA appeared first on Human Progress.
#DNA #CRISPRCAS9 -
EU split on deregulating gene-edited food as Council deadlock persists https://www.euractiv.com/section/agriculture-food/news/italys-first-gene-edited-crop-trial-sabotaged-as-deadlock-on-new-eu-rules-persists/?utm_source=dlvr.it&utm_medium=mastodon #Biotechnology #CRISPRCas9 #GMO #GMOs #newgenomictechniques
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EU split on deregulating gene-edited food as Council deadlock persists https://www.euractiv.com/section/agriculture-food/news/italys-first-gene-edited-crop-trial-sabotaged-as-deadlock-on-new-eu-rules-persists/?utm_source=dlvr.it&utm_medium=mastodon #Biotechnology #CRISPRCas9 #GMO #GMOs #newgenomictechniques
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CRISPR/Cas9 - Hoffen auf die Genschere als Heilmittel gegen Aids
Die Genschere CRISPR/Cas9 ruft große Hoffnung hervor, HIV heilen zu können. Der Beweis in der Forschung braucht aber wohl noch Jahre. Und es gibt auch Bedenken.#Genschere #GENTECHNIK #CRISPR-Cas9 #MEDIZIN #HIV #AIDS #Heilung
Genschere CRISPR/Cas: Wird Aids heilbar? -
CRISPR/Cas9 - Hoffen auf die Genschere als Heilmittel gegen Aids
Die Genschere CRISPR/Cas9 ruft große Hoffnung hervor, HIV heilen zu können. Der Beweis in der Forschung braucht aber wohl noch Jahre. Und es gibt auch Bedenken.#Genschere #GENTECHNIK #CRISPR-Cas9 #MEDIZIN #HIV #AIDS #Heilung
Genschere CRISPR/Cas: Wird Aids heilbar? -
Fachleute haben Menschen mit einer angeborenen Netzhauterkrankung erfolgreich mit der CRISPR-Genschere behandelt – direkt im Auge.#CRISPR #CRISPRCas9 #Gentherapie #Biotechnologie #Gentechnik #CRISPR-Cas9 #Medizin #Biologie
Blinde können dank Gentherapie sehen -
Fachleute haben Menschen mit einer angeborenen Netzhauterkrankung erfolgreich mit der CRISPR-Genschere behandelt – direkt im Auge.#CRISPR #CRISPRCas9 #Gentherapie #Biotechnologie #Gentechnik #CRISPR-Cas9 #Medizin #Biologie
Blinde können dank Gentherapie sehen -
🏆 After nearly 20 years, Italy wins a Human Frontier Science Program #HFSP Fellowship!
Congratulations to our Karthik Ramanadane, Postdoc in the Coscia Group (Structural #Biology), who will study the molecular mechanisms of the #thyroid at HT, using a combination of #proteomics, cell-based assay, #CRISPRCas9 based screening, and #cryoET and CLEM approaches.
https://humantechnopole.it/en/news/karthik-ramanadane-wins-a-hfsp-fellowship-for-thyroid-studies/
@hfsp #science #sciencemastodon #lifesciences #humantechnopole
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🏆 After nearly 20 years, Italy wins a Human Frontier Science Program #HFSP Fellowship!
Congratulations to our Karthik Ramanadane, Postdoc in the Coscia Group (Structural #Biology), who will study the molecular mechanisms of the #thyroid at HT, using a combination of #proteomics, cell-based assay, #CRISPRCas9 based screening, and #cryoET and CLEM approaches.
https://humantechnopole.it/en/news/karthik-ramanadane-wins-a-hfsp-fellowship-for-thyroid-studies/
@hfsp #science #sciencemastodon #lifesciences #humantechnopole
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A New #GeneKnockUp Approach to #Improve Plant #Traits
"Precisely regulating the expression of endogenous genes through #crisprcas9 gene editing #technology is crucial to achieve precise design and breeding of crops. The most widely used application of CRISPR/Cas9 technology in breeding is to knock out target genes, thereby achieving loss-of-function. However, the improvement of many agronomic traits …"
https://www.lifeasible.com/blog/a-new-gene-knock-up-approach-to-improve-plant-traits/
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Mit der CRISPR-Technologie werden neue Therapien möglich. Ein neues Medikament wird nun in der EU zugelassen. Was bedeutet das für die Medizin? 🎙️
Mit der CRISPR-Technologie werden neue Therapien möglich. Ein neues Medikament wird nun in der EU zugelassen. Was bedeutet das für die Medizin? Hier ent…#Wissen #Crispr #CRISPRCas9 #DNA #Erbkrankheit #Genetik #Genschere #Gentherapie #Krebsforschung #ZurückzumThema #Wissenschaft #Medizin #Technik #Forschung #Biologie #ErdeUmwelt #Kultur
detektor.fm: CRISPR: Mit der Genschere gegen Erbkrankheiten? -
Just Published!
"Tales of Discovery. Delving into the World of Biology and Medicine"
https://link.springer.com/book/10.1007/978-3-031-47620-4
This well-crafted popular science book is an informative resource for any one interested in gaining a deeper understanding of the most interesting topics in biology and medicine.
Enjoy!
#PopularScience #ScienceCommunication #Biology #Medicine #Nutrition #CRISPRCas9 #Nutrition #Diet #Microbiota #Aging #Genetics #Neuroscience #Books
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@wirhabenessatt nein danke! Die seit Jahrzehnten gefahrene Kampagne gegen die vermeintlichen Gefahren der Gentechnik sind bar jedweder wissenschaftlichen Grundlage - erst recht seit dem Einsatz von Präzisionsmethoden wie #CRISPRCas9.
Nicht die Methode, sondern das Ergebnis entscheidet.
Die "klassische Züchtung" unter Verwendung von Radioaktivität/UV-Strahlung/chemische Induktion erzeugt im Gegensatz dazu unvorhersehbare Resultate und sollte eigentlich das Ziel solcher Kampagnen sein.
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Eight major German and Austrian supermarkets say consumer choice, #organic must be protected from new #gmo s
"#EU regulations must guarantee full traceability and labelling of #NGT’s (new genomic techniques) throughout the supply chain"
https://www.gmwatch.org/en/106-news/latest-news/20336
#GeneticEngineering #geneEditing
#crispr #crisprcas9 #EUChooseSafeFood #patents #costofliving #CostOfLivingCrisis -
First CRISPR-Based Therapies For Sickle Cell Disease and Beta Thalassemia Approved In The UK
#science #crispr #crisprcas9 #genetherapy #hemoglobin #redbloodcells #hackaday
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First CRISPR-Based Therapies For Sickle Cell Disease and Beta Thalassemia Approved In The UK https://hackaday.com/2023/11/19/first-crispr-based-therapies-for-sickle-cell-disease-and-beta-thalassemia-approved-in-the-uk/ #redbloodcells #gene-therapy #CRISPRCaS9 #hemoglobin #Science #CRISPR
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First CRISPR-Based Therapies For Sickle Cell Disease and Beta Thalassemia Approved In The UK - The gene-therapy-based treatment called Casgevy was recently approved in the UK, m... - https://hackaday.com/2023/11/19/first-crispr-based-therapies-for-sickle-cell-disease-and-beta-thalassemia-approved-in-the-uk/ #redbloodcells #gene-therapy #crisprcas9 #hemoglobin #science #crispr
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3rd ARRIGE Albrecht Müller Seminar (free online conference) on ‘Human Therapeutic Applications of Gene Editing’ November 13th, 2023 – 2pm-5pm (CET) – Paris time.
#CRISPR #GenomeEditing #ClinicalTrials #BaseEditing #primeediting #crisprcas9 #genetherapy #advancedtherapies #ARRIGE #ResponsibleResearch #ethics #bioethics #rri #innovation
Full information and registrarion link to gain free access to this meeting available at:
https://www.arrige.org/portfolio/3rd-albrecht-muller-arrige-seminar/ -
@greenaspen @greenpeace_de @EU_Commission
(2/2)
...#agroindustrial #lobbies, #monopolization of then possible patents on food is bound to lead to further #oligopolization.
This is my take on a very long, detailed, and well presented article.
/END (for now)
#GM #GeneEditing #CRISPR #CRISPRcas9 #PrecautionaryPrinciple #food #ethics #PublicHealth
