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#fibrosis — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #fibrosis, aggregated by home.social.

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  1. Lipid #nanoparticles successfully delivered a full-length, healthy #CFTR gene into human airway cells, restoring essential biological function in a cystic #fibrosis model without the use of viral vectors.
    #Medical #Nanotechnology #Nanomedicine #GeneTherapy #PulmonaryMedicine #sflorg
    sflorg.com/2026/02/med02172601

  2. Lipid #nanoparticles successfully delivered a full-length, healthy #CFTR gene into human airway cells, restoring essential biological function in a cystic #fibrosis model without the use of viral vectors.
    #Medical #Nanotechnology #Nanomedicine #GeneTherapy #PulmonaryMedicine #sflorg
    sflorg.com/2026/02/med02172601

  3. Inhibition of the epigenetic co-activators p300/CBP prevents alveolar type 2 (AT2) cells from becoming trapped in a pathogenic "alveolar transitional cell state" (ATCS), thereby blocking the progression of idiopathic #pulmonary #fibrosis (#IPF ).
    #RegenerativeMedicine #Epigenetics #Genetics #Medical #sflorg
    sflorg.com/2026/02/gen02142601

  4. Inhibition of the epigenetic co-activators p300/CBP prevents alveolar type 2 (AT2) cells from becoming trapped in a pathogenic "alveolar transitional cell state" (ATCS), thereby blocking the progression of idiopathic #pulmonary #fibrosis (#IPF ).
    #RegenerativeMedicine #Epigenetics #Genetics #Medical #sflorg
    sflorg.com/2026/02/gen02142601

  5. When #inflammation in the body goes unchecked, it can cause #fibrosis, or tissue scarring that may lead to organ dysfunction or even failure. This can happen in conditions such as inflammatory bowel diseases (ulcerative colitis and Crohn’s disease), chronic viral infections, interstitial lung fibrosis, chronic autoimmune skin diseases such as scleroderma, and scars associated with heart disease.
    #MolecularBiology #Medical #sflorg
    sflorg.com/2026/01/mbio0107260

  6. When #inflammation in the body goes unchecked, it can cause #fibrosis, or tissue scarring that may lead to organ dysfunction or even failure. This can happen in conditions such as inflammatory bowel diseases (ulcerative colitis and Crohn’s disease), chronic viral infections, interstitial lung fibrosis, chronic autoimmune skin diseases such as scleroderma, and scars associated with heart disease.
    #MolecularBiology #Medical #sflorg
    sflorg.com/2026/01/mbio0107260

  7. @inkican

    "The drug, a manufactured antibody that attacks interleukin-11, is being trialled in patients with lung fibrosis. This is where the lungs become scarred, making it harder to breathe."

    Hope the trial is successful.

    #fibrosis #PulmonaryFibrosis #lungs #IL11

  8. @ScienceScholar

    Really exciting. I wish I could access the research article.

    I wonder if the anti-fibrotic alkaloids are dopamine agonists.*

    * doi.org/10.1126/scitranslmed.a

    #NaturalProducts #fibrosis

  9. Improved #pulmonary #function and #exercise #tolerance despite persistent pulmonary #fibrosis over 1 year after severe #COVID19 infection thorax.bmj.com/cgi/content/sho

    Despite a high prevalence of fibrotic patterns (64%), pulmonary function, #grip strength, 6 min #walk distance and frailty normalised. Overall, #dyspnoea, #cough and #exhaustion did not improve and were not correlated with pulmonary function or radiographic fibrosis at 15 months, suggesting non-respiratory aetiologies.

  10. Improved #pulmonary #function and #exercise #tolerance despite persistent pulmonary #fibrosis over 1 year after severe #COVID19 infection thorax.bmj.com/cgi/content/sho

    Despite a high prevalence of fibrotic patterns (64%), pulmonary function, #grip strength, 6 min #walk distance and frailty normalised. Overall, #dyspnoea, #cough and #exhaustion did not improve and were not correlated with pulmonary function or radiographic fibrosis at 15 months, suggesting non-respiratory aetiologies.

  11. #Cystic #fibrosis is a #genetic disease that causes serious and sometimes fatal #respiratory and #digestive disorders. A new treatment, available since 2020, improves lung function and quality of life. However, it does not always eradicate the #bacteria responsible for respiratory infections.
    #Biomolecular #Genetics #CF #sflorg
    sflorg.com/2024/04/bmol0404240

  12. #Cystic #fibrosis is a #genetic disease that causes serious and sometimes fatal #respiratory and #digestive disorders. A new treatment, available since 2020, improves lung function and quality of life. However, it does not always eradicate the #bacteria responsible for respiratory infections.
    #Biomolecular #Genetics #CF #sflorg
    sflorg.com/2024/04/bmol0404240

  13. #Cystic #fibrosis is the most common, life-limiting genetic condition in Australia. It affects the #lungs, #digestive system, and reproductive system, producing excess mucus, infections, and blockages.
    #Pharmaceutical #Nanotechnology #Medical #sflorg
    sflorg.com/2024/03/phar0329240

  14. #Cystic #fibrosis is the most common, life-limiting genetic condition in Australia. It affects the #lungs, #digestive system, and reproductive system, producing excess mucus, infections, and blockages.
    #Pharmaceutical #Nanotechnology #Medical #sflorg
    sflorg.com/2024/03/phar0329240

  15. Improved #pulmonary #function and #exercise #tolerance despite persistent pulmonary #fibrosis over 1 year after severe #COVID19 infection thorax.bmj.com/cgi/content/sho

    Overall, dyspnoea, cough and exhaustion did not improve and were not correlated with pulmonary function or radiographic fibrosis at 15 months, suggesting non-respiratory aetiologies.

  16. Improved #pulmonary #function and #exercise #tolerance despite persistent pulmonary #fibrosis over 1 year after severe #COVID19 infection thorax.bmj.com/cgi/content/sho

    Overall, dyspnoea, cough and exhaustion did not improve and were not correlated with pulmonary function or radiographic fibrosis at 15 months, suggesting non-respiratory aetiologies.

  17. PhD position in ERC funded project on myeloproliferative neoplasms

    RWTH Aachen

    Come and join us as a #PhD student to dissect molecular and cellular mechanisms in bone marrow #fibrosis in #MPN in an ERC funded research project.

    See the full job description on jobRxiv: jobrxiv.org/job/rwth-aachen-27...
    jobrxiv.org/job/rwth-aachen-27

  18. PhD position in ERC funded project on myeloproliferative neoplasms

    RWTH Aachen

    Come and join us as a #PhD student to dissect molecular and cellular mechanisms in bone marrow #fibrosis in #MPN in an ERC funded research project.

    See the full job description on jobRxiv: jobrxiv.org/job/rwth-aachen-27...
    jobrxiv.org/job/rwth-aachen-27

  19. PhD position in ERC funded project on myeloproliferative neoplasms

    RWTH Aachen

    Come and join us as a #PhD student to dissect molecular and cellular mechanisms in bone marrow #fibrosis in #MPN in an ERC funded research project.

    See the full job description on jobRxiv: jobrxiv.org/job/rwth-aachen-27...
    jobrxiv.org/job/rwth-aachen-27

  20. PhD position in ERC funded project on myeloproliferative neoplasms

    RWTH Aachen

    Come and join us as a #PhD student to dissect molecular and cellular mechanisms in bone marrow #fibrosis in #MPN in an ERC funded research project.

    See the full job description on jobRxiv: jobrxiv.org/job/rwth-aachen-27...
    jobrxiv.org/job/rwth-aachen-27

  21. Serum infrared spectral profile is predictive of the degree of hepatic fibrosis in chronic hepatitis C patients.
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
    Volume 305, 15 January 2024, 123433
    doi.org/10.1016/j.saa.2023.123
    #infrared #liver #fibrosis

  22. Serum infrared spectral profile is predictive of the degree of hepatic fibrosis in chronic hepatitis C patients.
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
    Volume 305, 15 January 2024, 123433
    doi.org/10.1016/j.saa.2023.123
    #infrared #liver #fibrosis

  23. We commonly use #nitrofurantoin to treat #UTI and even sometimes as prophylaxis for recurrent infections.

    Super safe #antibiotic but a reminder that rarely it can cause serious complications #lung #fibrosis
    @infectiousdiseases @microbiology #IDMastodon #MedMastodon #medicine

    Chronic Nitrofurantoin-Induced Lung Injury

    nejm.org/doi/full/10.1056/NEJM

  24. We commonly use #nitrofurantoin to treat #UTI and even sometimes as prophylaxis for recurrent infections.

    Super safe #antibiotic but a reminder that rarely it can cause serious complications #lung #fibrosis
    @infectiousdiseases @microbiology #IDMastodon #MedMastodon #medicine

    Chronic Nitrofurantoin-Induced Lung Injury

    nejm.org/doi/full/10.1056/NEJM

  25. People with weakened #immune systems are at constant risk of infection. #Pseudomonas #aeruginosa, a common #environmental #bacterium, can colonize different body parts, such as the #lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with #cystic #fibrosis.
    #Biology #Medical #sflorg
    sflorg.com/2023/06/bio06142302

  26. People with weakened #immune systems are at constant risk of infection. #Pseudomonas #aeruginosa, a common #environmental #bacterium, can colonize different body parts, such as the #lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with #cystic #fibrosis.
    #Biology #Medical #sflorg
    sflorg.com/2023/06/bio06142302

  27. science.org/doi/10.1126/sciadv

    "The ectopic activation of ERK in scar-prone injuries induced a pro-regenerative response, including cell proliferation, extracellular matrix remodeling, and hair follicle neogenesis. Our data detail an important distinction in ERK activity between regenerating and poorly regenerating adult mammals and open avenues to redirect fibrotic repair toward regenerative healing"

    #healing #fibrosis #scarTissue #enzyme #kinase #phosphorylation #mammalianBiology #mammal #scar