#fibrosis — Public Fediverse posts

Infosalus: Una #terapia #génica que edita el #ADN logra corregir en laboratorio una #mutación de #fibrosis #quística sin tratamiento

https://www.infosalus.com/salud-investigacion/noticia-terapia-genica-edita-adn-logra-corregir-laboratorio-mutacion-fibrosis-quistica-tratamiento-20260427075346.html

Lipid #nanoparticles successfully delivered a full-length, healthy #CFTR gene into human airway cells, restoring essential biological function in a cystic #fibrosis model without the use of viral vectors.
#Medical #Nanotechnology #Nanomedicine #GeneTherapy #PulmonaryMedicine #sflorg
https://www.sflorg.com/2026/02/med02172601.html

Inhibition of the epigenetic co-activators p300/CBP prevents alveolar type 2 (AT2) cells from becoming trapped in a pathogenic "alveolar transitional cell state" (ATCS), thereby blocking the progression of idiopathic #pulmonary #fibrosis (#IPF ).
#RegenerativeMedicine #Epigenetics #Genetics #Medical #sflorg
https://www.sflorg.com/2026/02/gen02142601.html

Hola Titánicos, hoy os explico que es a aracnoiditis, un trastorno que implica inflamación y daño de la aracnoide, una de las capas que componen las meninges que cubren el cerebro y la médula espinal, es decir, el sistema nervioso central.

https://somosdisca.es/que-es-la-aracnoiditis/

#aracnoiditis #aracnoiditisadhesiva #dolorneuropatico #dolor #dolorcronico #salud #enferrmedad #sistemanerviosocentral #infecciones #traumatismos #incontimencia #lesionmedular #fibrosis #enfermedadincapacitante #salud #enfermedad #saludmental #dependencia #Disability #disabilities #visibilidad #discapacidad #DiscapacidadAuditiva #visibilizandoladiscapacidad #enfermedadesraras #enferemdadrara #discapacidad #cuidados #vertigo #mareos #titanicos #titan #gentetitanica #somosdisca #somostitánicos

When #inflammation in the body goes unchecked, it can cause #fibrosis, or tissue scarring that may lead to organ dysfunction or even failure. This can happen in conditions such as inflammatory bowel diseases (ulcerative colitis and Crohn’s disease), chronic viral infections, interstitial lung fibrosis, chronic autoimmune skin diseases such as scleroderma, and scars associated with heart disease.
#MolecularBiology #Medical #sflorg
https://www.sflorg.com/2026/01/mbio01072601.html

Hola Titánicos, cada 8 de septiembre se celebra el día Mundial de la Fibrosis Quística, para visibilizar a esta enfermedad rara que afecta a 72.000 personas en el mundo

https://somosdisca.es/dia-mundial-de-la-fibrosis-quistica-2025/

#díaMundialdelaFibrosisQuística #FibrosisQuistica #FibrosisPulmonar #fibrosis #enfermedadrespiratoria #enfermedadpulmonar #salud #enfermedad #enferemdadrara #visibilidad #prevencion #saludmental #cuidados #cuidador #calidaddevida #DiscapacidadNoEsIncapacidad #incapacidadyjubilacion #incapacidad #disca #disability #disabilities #titan #titanicos #itanico #gentetitanica #somosdisca

Hola Tániticos, hoy os hablaré de lo qué es el Síndrome de la espalda fallida, en que consiste, sus síntomas, causas y como disminuye la calidad de vida de quien lo padece.

¿Después de una operación de columna persiste el dolor, incluso a aumentado? Quédate porque puede que esta información te interese.

https://somosdisca.es/que-es-el-sindrome-de-la-espalda-fallida/

#Síndromedelaespaldafallida #espaldafallida #españda #herniadedisco #herniadiscal #operaciondeespalda #operaciondecolumna #ProblemasDeColumna #radiculopatia #dolorcronico #dolor #unidaddedolor #cirugia #CirugiaFallida #fibrosis #CompresionNerviosa #hernia #DegeneracionDiscal #MovilidadRedicida ##SaludMental #Depresion #Ansiedad #Opiaceos #EstenosisForaminal #Estenosis #DolorRAdicular #InestabilidadLumbar #DolorLumbar #Lumbalgia #descompresiónMedular #EstenosisRadicular #infección #CalidadDeVida #MenosCalidadDeVida #Fisioterapia #Radiofrecuencia #Incontinencia #salud #enfermedad #discapacidad #disabilities #disability #Titan #Titanico#Titanicos #YosoyTitanico #GenteTitanica #Somosdisca

🔬🦴🩻🧪 Multifaceted bone response to immunomodulatory magnesium implants: Osteopromotion at the interface and adipogenesis in the bone marrow 🔍

https://doi.org/10.1016/j.biomaterials.2024.122779

#biomaterials #tissueengineering #regenerativemedicine #biology #implants #inflammation #immunomodulation #fibrosis #medicine #healthcare #engineering #magnesium #science

🔬🦴🧪 Magnesium implant degradation provides immunomodulatory and proangiogenic effects and attenuates peri-implant fibrosis in soft tissues" 🔎

https://doi.org/10.1016/j.bioactmat.2023.02.014

#biomaterials #tissueengineering #regenerativemedicine #biology #implants #inflammation #immunomodulation #fibrosis #medicine #healthcare #engineering #magnesium #science

@inkican

"The drug, a manufactured antibody that attacks interleukin-11, is being trialled in patients with lung fibrosis. This is where the lungs become scarred, making it harder to breathe."

Hope the trial is successful.

#fibrosis #PulmonaryFibrosis #lungs #IL11

@ScienceScholar

Really exciting. I wish I could access the research article.

I wonder if the anti-fibrotic alkaloids are dopamine agonists.*

* https://doi.org/10.1126/scitranslmed.aau6296

#NaturalProducts #fibrosis

Improved #pulmonary #function and #exercise #tolerance despite persistent pulmonary #fibrosis over 1 year after severe #COVID19 infection http://thorax.bmj.com/cgi/content/short/79/5/472?rss=1

Despite a high prevalence of fibrotic patterns (64%), pulmonary function, #grip strength, 6 min #walk distance and frailty normalised. Overall, #dyspnoea, #cough and #exhaustion did not improve and were not correlated with pulmonary function or radiographic fibrosis at 15 months, suggesting non-respiratory aetiologies.

#Cystic #fibrosis is a #genetic disease that causes serious and sometimes fatal #respiratory and #digestive disorders. A new treatment, available since 2020, improves lung function and quality of life. However, it does not always eradicate the #bacteria responsible for respiratory infections.
#Biomolecular #Genetics #CF #sflorg
https://www.sflorg.com/2024/04/bmol04042402.html

#Cystic #fibrosis is the most common, life-limiting genetic condition in Australia. It affects the #lungs, #digestive system, and reproductive system, producing excess mucus, infections, and blockages.
#Pharmaceutical #Nanotechnology #Medical #sflorg
https://www.sflorg.com/2024/03/phar03292401.html

Improved #pulmonary #function and #exercise #tolerance despite persistent pulmonary #fibrosis over 1 year after severe #COVID19 infection http://thorax.bmj.com/cgi/content/short/thorax-2023-220370v1?rss=1

Overall, dyspnoea, cough and exhaustion did not improve and were not correlated with pulmonary function or radiographic fibrosis at 15 months, suggesting non-respiratory aetiologies.

PhD position in ERC funded project on myeloproliferative neoplasms

RWTH Aachen

Come and join us as a #PhD student to dissect molecular and cellular mechanisms in bone marrow #fibrosis in #MPN in an ERC funded research project.

See the full job description on jobRxiv: https://jobrxiv.org/job/rwth-aachen-27778-phd-position-in-erc-funded-project-on-myeloproliferative-ne...
https://jobrxiv.org/job/rwth-aachen-27778-phd-position-in-erc-funded-project-on-myeloproliferative-neoplasms/?feed_id=72666

PhD position in ERC funded project on myeloproliferative neoplasms

RWTH Aachen

Come and join us as a #PhD student to dissect molecular and cellular mechanisms in bone marrow #fibrosis in #MPN in an ERC funded research project.

See the full job description on jobRxiv: https://jobrxiv.org/job/rwth-aachen-27778-phd-position-in-erc-funded-project-on-myeloproliferative-ne...
https://jobrxiv.org/job/rwth-aachen-27778-phd-position-in-erc-funded-project-on-myeloproliferative-neoplasms/?feed_id=71735

An #m6A-independent function of #YTHDC1: its expression delays cellular #senescence and pulmonary #fibrosis by interacting with #TopBP1 to activate ATR
https://www.embopress.org/doi/full/10.1038/s44318-023-00003-2

Serum infrared spectral profile is predictive of the degree of hepatic fibrosis in chronic hepatitis C patients.
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
Volume 305, 15 January 2024, 123433
https://doi.org/10.1016/j.saa.2023.123433
#infrared #liver #fibrosis

We commonly use #nitrofurantoin to treat #UTI and even sometimes as prophylaxis for recurrent infections.

Super safe #antibiotic but a reminder that rarely it can cause serious complications #lung #fibrosis
@infectiousdiseases @microbiology #IDMastodon #MedMastodon #medicine

Chronic Nitrofurantoin-Induced Lung Injury

https://www.nejm.org/doi/full/10.1056/NEJMicm2214831

People with weakened #immune systems are at constant risk of infection. #Pseudomonas #aeruginosa, a common #environmental #bacterium, can colonize different body parts, such as the #lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with #cystic #fibrosis.
#Biology #Medical #sflorg
https://www.sflorg.com/2023/06/bio06142302.html

Postdoctoral Researcher (all genders) Fibrosis and Wound Healing @BioMed_X

The BioMed X Institute is establishing a new, fully funded research group at its new XSeed Labs incubator.

https://jobrxiv.org/job/biomed-x-institute-27778-postdoctoral-researcher-all-genders-fibrosis-and-wound-healing/?feed_id=44478

#ScienceJobs #job #fibrosis #woundhealin...
https://jobrxiv.org/job/biomed-x-institute-27778-postdoctoral-researcher-all-genders-fibrosis-and-wound-healing/?feed_id=44478

Postdoctoral Researcher (all genders) Fibrosis and Wound Healing @BioMed_X

The BioMed X Institute is establishing a new, fully funded research group at its new XSeed Labs incubator.

https://jobrxiv.org/job/biomed-x-institute-27778-postdoctoral-researcher-all-genders-fibrosis-and-wound-healing/?feed_id=43758

#ScienceJobs #job #fibrosis #woundhealin...
https://jobrxiv.org/job/biomed-x-institute-27778-postdoctoral-researcher-all-genders-fibrosis-and-wound-healing/?feed_id=43758