#medmastodon — Public Fediverse posts

The October 2026 issue of Acta Paediatrica is now available online
#NeoMastodon #Pediatrics #MedMastodon #Nicuverse
https://onlinelibrary.wiley.com/toc/16512227/2026/115/10

Do inpatient Geriatrics models actually improve care for older adults?

In 28,833 hospital encounters, ACE Units & Geriatrics Consults raised adherence to the 4Ms framework vs. usual care. But effects on outcomes were mixed. Consults alone linked to fewer 30-day readmissions, while ACE+Consult tied to more. Only ACE units with high adherence shortened stays.

Better adherence ≠ uniformly better outcomes. #Implementation matters.

#Geriatrics #Frailty #Care #MedMastodon

🔗 https://doi.org/10.1111/jgs.70666

The July 2026 issue of Acta Paediatrica is now available online 🙂
https://onlinelibrary.wiley.com/toc/16512227/2026/115/7
#NeoMastodon #Pediatrics #MedMastodon #Nicuverse

Also guys / people who don't get periods need the HPV vaccine too. It's a virus: Human Papilloma Virus effects are not restricted to one organ.

Relevant period advice:

https://www.youtube.com/watch?v=Yjvn4Uc4xWM
https://www.youtube.com/watch?v=Mg5gZ5Qzwwk
https://www.youtube.com/watch?v=3_W2-L9-jAE
https://www.youtube.com/watch?v=llqbYlhfgZU
https://www.youtube.com/watch?v=XQDx4JtU3vE
https://www.youtube.com/watch?v=7t3fseRvzLs
https://www.youtube.com/watch?v=Ez88w5dd1oU
https://www.youtube.com/watch?v=cDA5z4z-8gM

I strongly recommend telling all docs about CareVix (a suction tool, not stabby or piercing) and YonaCare speculum.

#Menstruation #periods #monthly #PreMenstrualDysphoric #PreMenstrualDysphoriaDisorder #blood #endometriosis #PelvicInflammatoryDisease #HPV #vaccine #opioid #MissingWork #MissingSchool #ActivitiesOfDailyLiving #ADL #debilitating #disabling #cramps #PeriodCramps #pain #science #ScienceMastodon #MedMastodon #Medicine #GynOb #ObGyn #gynaecology

Hey, isn't that weird to call it ObGyn or OBGYN instead of, say, GynOb or GYNOB?
You have a vaj and gut sack before you have anything in there, obviously.

https://zerotofinalsshop.com/products/zero-to-finals-obstetrics-and-gynaecology

Also the trans mascs might like to go see a Guy Knob doctor, idk.

#gyn #ObGyn #medMastodon

med-mastodon.com is now back online!

Andrew Young’s post on the return of med-mastodon

Okay #MedMastodon folks - The instance is now back up and running I’m pleased to share. Things might take a moment to catch-up and I have sent out an announcement so hopefully anyone that had accounts that doesn’t see this will get the e-mail ping letting them know everything is currently back online.
I will post a bit more about the plan in the near future but the long story short is nothing is planned to change that folks will see, the main goal for me is to get the site up and running, catch up on the activities that look to be outstanding and get a plan together for migrating everything onto new infrastructure.
.
Also a huge shoutout to #mastohost who have been excellent at keeping the server “Paused” effectively without deleting data even when there was no confirmed migration path and a real big thanks to Nick for being willing to transfer the server and keep the community running!

#MedMastodon

https://zeroes.ca/@ndrwy/115844033769975967

https://piefed.social/c/fediverse/p/1639937/med-mastodon-com-is-now-back-online

Causal relationships between #sarcopenia, #frailty, and #health outcomes: A systematic review of Mendelian randomization studies

#Geriatrics #Care #Research #MedMastodon

https://www.sciencedirect.com/science/article/pii/S0531556525002827?dgcid=rss_sd_all

Metformin reduces risk of Long Covid. https://thesicktimes.org/2025/10/28/metformin-has-been-shown-to-reduce-the-risk-of-long-covid-why-isnt-it-more-widely-used/?mc_cid=01de0f1b88&mc_eid=4b751fcf19

#TheSickTimes #LongCovid #ProlongedPandemic #pandemic #disease #illness #sick #chronic #MedMastodon #medicine #medical #Metformin #Rapamycin #diagnose #prognosis #wellness #digestion #diabetes #hba1c #doctor #doctors #clinic #GP #physicians

... Huh. https://depressioneducation.org/mood-spectrum-mood-swings-without-mania/
This makes sense. We don't have one single "mood hormone" or even receptor type in cells, so why would we have one single "correct" mood set? https://depressioneducation.org/depression-section-page-1/the-dsm-rules-for-psych-diagnosis/
... Psychiatryst, lol. That needs to be an ERP game or something. And psychologussy. I should be sorry but I'm so not.

#MedMastodon #SensitisedNervousSystem #SystemicProblemsNeedSystemicSolutions #Depression #PTSD #MentalHealth #MentalIllness #Anxiety #Mood #Moody #DisorderedMood #MoodDisorder #HSP #HighlySensitivePerson #SensitisedNeurons #SebsitisedSynapses #SensitisedNerves #SystemicDisease #cPTSD #Psychiatry #Psychiatrist #Psychology #Psychologist #Treatment #MisTreatment #Modalities #OortArtCloud

1. https://www.mkuh.nhs.uk/wp-content/uploads/2022/10/Women-with-Disabilities-and-Special-Needs-Guideline.pdf
2. https://bmjopen.bmj.com/content/7/7/e016757
3. https://rcm.org.uk/blog/2025/06/improving-maternity-care-and-support-for-pregnant-women-with-disabilities/
4. https://birthrights.org.uk/factsheets/disability-and-long-term-health-conditions-and-maternity-care/
5. https://criplife.co.uk/pregnancy-and-disability-ensuring-inclusive-maternity-care-for-prospective-disabled-mothers/
6. https://www.ableize.com/health-and-fitness/pregnancy-and-parenthood/

I guess obstretics is My New Thing.

#maternity #pregnancy #ObGyn #Obstetrics #pregnant #nativity #disabled #DisabledJoy #DisabledFedi #disability #MedMastodon #med #meds #medicine #medical

https://www.mkuh.nhs.uk/wp-content/uploads/2022/10/Women-with-Disabilities-and-Special-Needs-Guideline.pdf "Appendix 1: MOTHERS WITH LEARNING DISABILITIES GUIDANCE TOOL
V
Value family – Involve individuals who best know the woman with learning disabilities as they can provide additional information that may be helpful to the decision-making process.
A
Avoid making assumptions – Do not assume that because someone has a diagnosis of a learning disability that they cannot be good enough parents
L
Look for support – Professionals should not work in isolation and should involve learning disability services for further support and guidance.
U
Understand emotions – Take into consideration that many mothers with learning disabilities have their own anxieties and worries about motherhood and fear of judgment. Do not assume they are being difficult.
E
Establish reasonable adjustments – Professionals should put reasonable adjustments into place to ensure women with learning disabilities can comprehend and understand information to give informed consent. I.E. easy read, pictorials, large font, visual and hearing aids.

M
Mental Capacity – Do not assume capacity. In liaison with the Mental Capacity Act 2005, professionals should consider completing a Mental Capacity Assessment (MCA) to establish whether the women can give informed consent. Professionals should also consider best interest, Deprivation of Liberty Safeguards (DoLS) and involving an Independent Mental Capacity Advocate (IMCA).
E
Efficient discharge – Professionals should consider possible support that can be put into place to ensure a person-centered discharge is consolidated. Consider, access to health and additional services, transport, financial support and accommodation.

THINK... VALUE ME"

#maternity #pregnancy #ObGyn #Obstetrics #pregnant #nativity #disabled #DisabledJoy #DisabledFedi #disability #MedMastodon #med #meds #medicine #medical

Omfg. Read section 3.4 "Learning Disabilities support" on page 5. Literally everyone will be helped by these suggestions, not just diagnosed disabled people.
https://www.mkuh.nhs.uk/wp-content/uploads/2022/10/Women-with-Disabilities-and-Special-Needs-Guideline.pdf
"3.4 Learning Disabilities support
Although 7% of people with learning disabilities become parents ( Best Beginnings) the Equality Act 2010 obligates responsibility to service providers to ensure that reasonable adjustments are put into place to ensure the holistic needs of people with learning disabilities are met to the highest standards.
Remember to think VALUE ME! (Appendix 1)

1. Early intervention strategies should be considered. Ensure that the community midwife is involved and if they are under 20 consider discussion with the specialist teenage pregnancy midwife for additional support.
2. Professionals should ensure that adequate time is provided for consultations, appointments and formal discussions. Taking time to allow the woman to understand the information in
order to make an informed decision.
3. Professionals should ensure that reasonable adjustments are put into place to aid with understanding. Including: easy read, pictorials, large font, visual and hearing aids.
4. Abilities led practice rather than inabilities led practice. Professionals should avoid making assumptions based on a diagnosis of a learning disability as often mothers will have their own anxieties, fears and worries regarding motherhood.
5. Avoid assuming that mothers are being difficult. Consider other possible reasons such as the environment, loud noises, bright lights (especially if they have a dual diagnosis of learning disability and ASD), sensory needs, stress and anxiety. Provide a side room if possible."

#maternity #pregnancy #ObGyn #Obstetrics #pregnant #nativity #disabled #DisabledJoy #DisabledFedi #disability #MedMastodon #med #meds #medicine #medical

Adherence to #Guideline Recommendations on Psychotropic #Drug Use for Challenging Behavior in #Dementia

"...Of all newly started prescriptions, 17% were evaluated within the recommended 7 days after starting..."

#Geriatrics #Care #Alzheimers #Deprescribing #MedMastodon

https://www.jamda.com/article/S1525-8610(24)00897-1/fulltext?dgcid=raven_jbs_etoc_email

[1/5] Auch in diesem Jahr sind an der #CharitéBerlin wieder neue Projekte gestartet, die Forschung und direkte klinische Anwendbarkeit verbinden - kofinanziert aus Mitteln des Europäischen Fonds für regionale Entwicklung (#EFRE). Drei davon stellen wir heute vor.

#Medizin #BessereMedizin #Forschung #Foerderung #Europa #Medmastodon

Systematic #review of #guideline recommendations for older and frail adults with type 2 #diabetes mellitus | Age & #Ageing

"...proportionately less #recommendations for individuals who are frail..."

#Geriatrics #Frailty #Health #Care #Therapy #MedMastodon
https://academic.oup.com/ageing/article/53/11/afae259/7906521

Audiograms and Prevalence of Hearing Loss in U.S. Children and Adolescents 6–19 Years of Age
L Humes 2024, JSLHR

"For children and adolescents in the United States, hearing was unaffected by differences in sex and race/ethnicity, with only age impacting pure-tone thresholds and only at the lowest (500 Hz) and highest (8000 Hz) frequencies examined. The overall prevalence of hearing loss was about 11%."

https://pubs.asha.org/doi/full/10.1044/2024_JSLHR-24-00050

#Science #Auditory #Sensory #Audiology #MedMastodon

FYI - These are the kind of emails I send out to #medical facilities that I have to go to. I don't fucking play around!

#BCpoli #BCPublicHealth #FireBonnieHenry #OathbreakerBonnie #Eugenics #MaskUp #C19 #CovidIsNotOver #CovidSafety #BCNDP #BCNewDeathParty #BCNDPLegacyoOfDeath #ConfrontAntimaskers #PublicHealthAdvocacy #FAFO #PlagueSpreaders #health #MedMastodon #Covid #ZeroCovid

The experience of stigma related to hearing loss and hearing aids: perspectives of adults with hearing loss, their families, and hearing care professionals
Nickbakht et al., 2024

"Hearing care professionals focused on the stigma of hearing aids more than hearing loss, whereas adult participants focused on stigma of hearing loss. Family member data indicated that they experienced little affiliate stigma."

https://www.tandfonline.com/doi/full/10.1080/14992027.2024.2353862

#Auditory #HearingAids #Stigma #Audiology #MedMastodon

Für seinen herausragenden Beitrag zur #Lungenphysiologie: Prof. Wolfgang Kübler von der #CharitéBerlin erhält Julius H. Comroe Jr. Distinguished Lectureship der American Physiology Society. Herzlichen Glückwunsch! 👏

👉 https://www.charite.de/forschung/themen_forschung/2024/wolfgang_kuebler_geehrt/

#Medizin #Forschung #Wissenschaft #Auszeichnung #BessereMedizin #CharitéBiomedizin #MedMastodon #Medibubble #Physiologie

Pharmacogenetics Applied to the Treatment of Psychiatric Illness |
Fralin Biomedical Research Institute

Presentation by David Oslin, M.D., U Penn.

To: All prescribers of any type of Rx drug

Please watch. This is important.

-- signed, mother of a child who had neuroleptic malignant syndrome from Reglan / metoclopramide

https://www.youtube.com/live/nl4v2IDSHp8?si=C2PxyUS-S9wHbw4k

#medicine #MedMastodon #tootRx #pharmacology #Pharmacogenetics #pharmacy

Happiness with Circumcision Status, Not Status Itself, Predicts Genital Self-Image in a Geographically Diverse Sample
Selino & Krawczyk, 2023 Archives of Sexual Behavior

"Participants who were circumcised tended to have less happiness with their circumcision status than non-circumcised participants regardless of region of birth."

https://link.springer.com/article/10.1007/s10508-023-02543-4

#MedMastodon #Autonomy #BodilyAutonomy #GenitalAutonomy #Feminism

🚀 Völlig losgelöst von der Erde 🌍

Wer Schwerelosigkeit, Kälte & Isolation erforschen will, kann sich dafür jetzt ausbilden lassen: Ab dem WS2024 bietet die #CharitéBerlin gemeinsam mit der Université de Caen Normandie und der Jožef Stefan International Postgraduate School den Masterstudiengang für #Weltraummedizin 👨‍🚀👩‍🚀 & #Physiologie in extremen Umwelten 🗻 an.

Jetzt bis 1. März bewerben!

👉 https://www.charite.de/service/pressemitteilung/artikel/detail/neu_an_der_charite_internationaler_masterstudiengang_weltraummedizin/

#MedMastodon #Master #CharitéSpaceMed #Studium #Weltall #Astronomie #Raumfahrt

Salut les docs !
Je me suis lancé dans un DIU à l’unif de Paris sur l’échographie clinique en medecine polyvalente 🥳 Je suis à la recherche de médecins spécialistes (radiologues mais pas uniquement !) localisés en Belgique 🇧🇪 qui utiliseraient l’echo au quotidien et qui accepteraient de me montrer comme a un stagiaire pendant qq heures seulement (4-5) leur usage pour m’aider dans mon apprentissage :) #mastomed #medmastodon #doctoctoc #pocus #echographie

Salut les docs !
Je me suis lancé dans un DIU à l’unif de Paris sur l’échographie clinique en medecine polyvalente 🥳 Je suis à la recherche de médecins spécialistes (radiologues mais pas uniquement !) localisés en Belgique 🇧🇪 qui utiliseraient l’echo au quotidien et qui accepteraient de me montrer comme a un stagiaire pendant qq heures seulement (4-5) leur usage pour m’aider dans mon apprentissage :) #mastomed #medmastodon #doctoctoc #pocus #echographie

Salut les docs !
Je me suis lancé dans un DIU à l’unif de Paris sur l’échographie clinique en medecine polyvalente 🥳 Je suis à la recherche de médecins spécialistes (radiologues mais pas uniquement !) localisés en Belgique 🇧🇪 qui utiliseraient l’echo au quotidien et qui accepteraient de me montrer comme a un stagiaire pendant qq heures seulement (4-5) leur usage pour m’aider dans mon apprentissage :) #mastomed #medmastodon #doctoctoc #pocus #echographie

Salut les docs !
Je me suis lancé dans un DIU à l’unif de Paris sur l’échographie clinique en medecine polyvalente 🥳 Je suis à la recherche de médecins spécialistes (radiologues mais pas uniquement !) localisés en Belgique 🇧🇪 qui utiliseraient l’echo au quotidien et qui accepteraient de me montrer comme a un stagiaire pendant qq heures seulement (4-5) leur usage pour m’aider dans mon apprentissage :) #mastomed #medmastodon #doctoctoc #pocus #echographie

#Articular #cartilage, which is a type of #tissue found in #joints, allows for nearly frictionless motion and can absorb large loads. Unfortunately, when it is damaged, it cannot repair itself. #Tissueengineering is a promising approach to repair the damage, but it falls short of creating functional tissue. This is because the tissue-engineered constructs do not have the same mechanical properties as native articular cartilage, which is due to the insufficient accumulation of #extracellular matrix components. To address this, researchers have been exploring the use of adenosine triphosphate (#ATP) to directly harness the underlying mechanotransduction pathways responsible. ATP is a molecule that is released as a result of mechanical stimulation and acts as an autocrine/paracrine signaling #molecule. It acts on P2 receptors on the #plasma #membrane to promote extracellular matrix #synthesis. However, high doses of ATP can lead to an increase in matrix #metalloproteinase 13 (MMP-13) activity and extracellular inorganic pyrophosphate (ePPi) accumulation, which can lead to undesirable effects such as #mineralization of articular cartilage. Therefore, the purpose of this study is to identify the mechanism of ATP-mediated #catabolism and to determine a therapeutic dose range to maximize the #anabolic effect.

Materials & Methods

Cell Isolation: This is the process of separating cells from a tissue sample. It is usually done using #enzymes to break down the tissue and then filtering the cells out.

3-Dimensional Culture: This is a type of #cellculture where the cells are grown in a three-dimensional environment, rather than in a flat layer. This allows the cells to interact with each other in a more natural way.

Exogenous ATP Supplementation: ATP (adenosine triphosphate) is a molecule that is important for energy production in cells. Exogenous ATP supplementation is the process of adding ATP to the cell culture from an outside source. This can help the cells to grow and function better.

MMP-13 Protein Activity is a type of protein that is found inside cells. It was extracted from 3-D cultured constructs and then frozen and pulverized. It was then homogenized in a buffer solution with a protease inhibitor. After that, it was centrifuged and stored at a low temperature. To measure the amount of active MMP-13, a FRET-based assay was used. This assay uses a fluorophore and quencher to measure the amount of MMP-13 that is present. To measure the amount of ECM synthesis, a range of exogenous ATP doses were used. To measure the effect of PPi on MMP-13 activity, chondrocyte monolayer cultures were established and PPi was added to the cultures. To investigate the underlying mechanisms, inhibitors were added to the cultures. Finally, Transmission Electron #Microscopy (TEM) was used to determine the presence of CPPD #crystal accumulation in the engineered tissue constructs. Statistical analyses were then used to analyze the collected data.

The researchers found that when they added ATP to the cultures, MMP-13 activity increased in a dose-dependent manner. This means that the more ATP they added, the more MMP-13 activity increased. They also found that the levels of PPi in the media increased significantly when they added a high dose of ATP, but the levels of PPi in the tissue did not appear to be affected. To determine the best dose of ATP to use, the researchers tested a range of doses and measured the effects on ECM synthesis (collagen and proteoglycans) and MMP-13 activity. They found that ECM synthesis and MMP-13 activity increased in response to intermediate doses of ATP, and further increased in response to higher doses of ATP.

In this study, the researchers wanted to see if they could use ATP to improve tissue growth and mechanical properties without the need for mechanical loading. They found that while high doses of ATP (250 μM) had a positive effect, it also caused a catabolic response, which is when the tissue breaks down. To find the optimal dose of ATP, the researchers tested different doses (31.25, 62.5, and 125 μM) to see which one had the best effect on tissue growth and mechanical properties without causing a catabolic response.

#Calcium is an important factor in the ATP-mediated catabolism process. The researchers found that when they added 10 μM PPi to #chondrocyte cultures, there was a 32% increase in MMP-13 activity compared to unstimulated controls. This effect appeared to require calcium and could be inhibited by the MEK1/2 inhibitor U0126. Additionally, TEM imaging was conducted on engineered cartilaginous tissues supplemented with 0, 62.5 and 250 μM ATP but no mineralization or CPPD crystals were observed which suggests that these doses of ATP did not cause any catabolic response due to crystal formation.

The text is discussing a method of improving tissue growth and mechanical properties of engineered cartilage constructs by applying mechanical loading. However, this approach has limitations when dealing with irregular geometry and high radii of curvature. An alternative approach is to use the known mechanotransduction pathways responsible to achieve the same effect without externally applied forces. In a recent study, it was demonstrated that direct stimulation of the ATP-purinergic receptor pathway through exogenous supplementation of ATP can elicit a comparable anabolic response and be used to improve both tissue growth and mechanical properties of the developed tissue. However, high doses of ATP (250 μM) resulted in a simultaneous catabolic response characterized by an increase in MMP-13 expression, potentially due to the accumulation of ePPi. The present study determined a therapeutic dose range of exogenous ATP to maximize the anabolic response and minimize the catabolic effect of exogenous ATP. It was found that the dose range of ATP between 62.5 and 125 μM was optimal for maximizing the anabolic effect and minimizing the catabolic effect of exogenous ATP. It was also found that calcium and pyrophosphate were key factors involved in the PPi-mediated catabolic response, and that CPPD crystals could potentially be endocytosed and elicit changes through a MAPK-dependent pathway.

#explainpaper #med #MedMastodon

The Therapeutic Potential of Exogenous Adenosine Triphosphate (ATP) for Cartilage Tissue Engineering

authors : Jenna Usprech , Gavin Chu , Renata Giardini-Rosa , Kathleen Martin , and Stephen D. Waldman

Therefore, here is a more lengthy #introduction:

I used to follow and learn from #medtwitter and #HITsm; I wonder if this moves now to #medmastodon? Given my #healthcare IT interest, I am particularly interested in understanding #customerneeds and providing #customervalue. On the technical side, I look for #interoperability topics and standards such as #HL7 #FHIR in the context of #eHealth, #healthcare infrastructure, and networks. For all of that, there is a need for #cloud platforms, #workflow, #processautomation, and in the long run, #LCNC.

C’est de saison :
Intérêt de l’échographie pour diagnostiquer une pneumonie bactérienne en cas de bronchiolite chez les enfants…
Exerçons notre oeil a bien voir les lignes B, consolidations sous pleurales avec bronchogramme aerique et consolidations de plus d’un centimètre…

https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-018-0750-1 #pocus #échographie #pocusfirst #mastomed #medmastodon

Liste de quelques ressources utiles pour se perfectionner en échographie/POCUS ...
N'hésitez pas à compléter !

https://www.pocus101.com/
https://www.acep.org/sonoguide/basic/cardiac/
https://www.coreultrasound.com/5ms/
https://criticalcarenorthampton.com/pocusgrams/
https://www.ultrasoundgel.org/
https://www.thepocusatlas.com/
https://www.youtube.com/channel/UCa8E0tiub9FEu5_AsW3gYkQ/videos
https://www.youtube.com/channel/UCQvFU8nSXrQIeIp-KbsL3Jg/videos
https://www.echo-loco.fr/

#pocus #pocusfirst #échographie #meded #Foamus #medmastodon #mastomed #médecine #ultrasound

Quel bonheur que de pouvoir directement faire un diagnostic de pneumonie avec certitude sans attendre le résultat de la bio ! … #medecinegenerale #lus #echographie #pocusfirst #medmastodon #doctoctoc

Quel bonheur que de pouvoir directement faire un diagnostic de pneumonie avec certitude sans attendre le résultat de la bio ! … #medecinegenerale #lus #echographie #pocusfirst #medmastodon #doctoctoc

Petite devinette, que pensez-vous de ceci ? POCUS en FIG dans le cadre d'une fatigue, perte de poids, nausées,...

What do you think of this ?
fatigue, weight loss, POCUS in the left iliac fossa showing this :

#echofirst #MedMastodon #pocus #échographie #pocusfirst #doctoctoc #mastodoc

Petite devinette, que pensez-vous de ceci ? POCUS en FIG dans le cadre d'une fatigue, perte de poids, nausées,...

What do you think of this ?
fatigue, weight loss, POCUS in the left iliac fossa showing this :

#echofirst #MedMastodon #pocus #échographie #pocusfirst #doctoctoc #mastodoc

Petite devinette, que pensez-vous de ceci ? POCUS en FIG dans le cadre d'une fatigue, perte de poids, nausées,...

What do you think of this ?
fatigue, weight loss, POCUS in the left iliac fossa showing this :

#echofirst #MedMastodon #pocus #échographie #pocusfirst #doctoctoc #mastodoc

@speechwoman @CarolineBowen this *is* #QuiteInteresting! I was wondering what delete and redraft would look like. I also found out that diff instances have their own emojis. I'm very jealous of #Medmastodon emojis.