#senescence — Public Fediverse posts

https://www.europesays.com/ch-fr/103035/ Exploiter une nouvelle faiblesse des cellules « de type zombie » pour traiter les maladies associées à la sénescence #associées #cellules #des #exploiter #faiblesse #Health #les #Maladies #nouvelle #pour #Santé #sénescence #Suisse #traiter #type #Une #Zombie

📃New paper in Ecology letters 🐦 by ‪Bertille Mohring et al.

Life-history trade-offs and #senescence in black-browed #albatrosses from Kerguelen and Bird Island

Black-browed #albatrosses breeding in more variable environments display slower life histories (slow, late-onset reproductive senescence) and greater among-individual variation in life-history strategies

https://doi.org/10.1111/ele.70384

#seabird #ecology #science

https://www.europesays.com/ch-fr/81723/ La longévité se joue aussi… dans la tête #Âge #BryanJohnson #curiosité #Health #longévité #mental #Optimisme #Santé #sénescence #Suisse #vieillissement

https://www.europesays.com/be-fr/68241/ La longévité se joue aussi… dans la tête #Age #BE #BEFr #Belgique #Belgium #BryanJohnson #curiosité #Health #longévité #mental #Optimisme #Santé #sénescence #vieillissement

Cellular #senescence is a biological paradigm in which a unique subpopulation of cells permanently and irreversibly stops dividing but evades apoptosis (programmed cell death). Instead of dying off, these arrested "zombie cells" remain metabolically hyperactive and linger within mammalian tissues.
#WhatIs #MolecularBiology #CellBiology #Geroscience #Longevity #sflorg
https://www.sflorg.com/2026/03/wi03202601.html

#SilentSunday

Marcescence
…still holding on 😊
Not senescence in this case 🤔

#GetOutside #Hiking #Nature #Walking #Creek #Marcescence #Senescence #Aging #Meditation #Photography

my reading for this evening -

Aging: a possible road toward gut microbiota pathoadaptation [2025]
https://pubmed.ncbi.nlm.nih.gov/40770832/

#aging #senescence #GutMicrobiome #pathoadaptation

my reading for this evening -

Aging: a possible road toward gut microbiota pathoadaptation [2025]
https://pubmed.ncbi.nlm.nih.gov/40770832/

#aging #senescence #GutMicrobiome #pathoadaptation

my reading for this evening -

Aging: a possible road toward gut microbiota pathoadaptation [2025]
https://pubmed.ncbi.nlm.nih.gov/40770832/

#aging #senescence #GutMicrobiome #pathoadaptation

my reading for this evening -

Aging: a possible road toward gut microbiota pathoadaptation [2025]
https://pubmed.ncbi.nlm.nih.gov/40770832/

#aging #senescence #GutMicrobiome #pathoadaptation

my reading for this evening -

Aging: a possible road toward gut microbiota pathoadaptation [2025]
https://pubmed.ncbi.nlm.nih.gov/40770832/

#aging #senescence #GutMicrobiome #pathoadaptation

Pink Flamingos Reveal Their Secret To Aging

"Migration has critical impacts on life trajectories by shaping mortality and reproductive outcomes. These findings are important for our knowledge on the biology of aging."

#SciComm by @grrlscientist

#Aging #migration #ornithology #birds #flamingo #biology #Senescence #FieldStudy https://grrlscientist.medium.com/pink-flamingos-reveal-their-secret-to-aging-758ff6fed667

Pink Flamingos Reveal Their Secret To Aging

"Migration has critical impacts on life trajectories by shaping mortality and reproductive outcomes. These findings are important for our knowledge on the biology of aging."

#SciComm by @GrrlScientist

#Aging #migration #ornithology #birds #flamingo #biology #Senescence #FieldStudy https://grrlscientist.medium.com/pink-flamingos-reveal-their-secret-to-aging-758ff6fed667

Pink Flamingos Reveal Their Secret To Aging

"Migration has critical impacts on life trajectories by shaping mortality and reproductive outcomes. These findings are important for our knowledge on the biology of aging."

#SciComm by @grrlscientist

#Aging #migration #ornithology #birds #flamingo #biology #Senescence #FieldStudy https://grrlscientist.medium.com/pink-flamingos-reveal-their-secret-to-aging-758ff6fed667

Scientists Have Discovered a Special Type of Immune Cell That Slows Aging

Researchers have just discovered a way to destroy harmful 'senescent' cells that accumulate with age and ramp up the kind of tissue damage and inflammation that slowly brings life to a grinding halt.

The team found that CD4 T immune cells transform into assassins of the damaging tissues when biological aging is detected in the body.

https://www.sciencealert.com/scientists-have-discovered-a-special-type-of-immune-cell-that-slows-aging

#ageing
#senescence
#CD4Eomes

The lab published a nice paper, so we celebrated at our Friday lab meeting 🎉

https://www.sciencedirect.com/science/article/abs/pii/S0014482725004288

#Publication #Science #GraduateSchool #BiomedicalSciences #Timeless #Cancer #Research #Senescence

Cellular Senescence in Health, Disease and Aging: Blessing or Curse? by Markus Riessland, 2021

When Hayflick and Moorhead coined the term “cellular senescence” (CS) almost 60 years ago, this phenomenon was understood as a mechanism, usually induced by activation of the DNA-repair machinery, to prevent uncontrolled proliferation.

#OpenAccess

https://directory.doabooks.org/handle/20.500.12854/76942

#books
#senescence
#CS

SoCal octopus will spend final days caring for eggs that won’t hatch

A beloved octopus is entering the last stage of her life in Long Beach,and will spend the remainder…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Wildlife #aquarium #egg #finalday #Ghost #giantpacificoctopus #life #lifecycle #natejaros #octopus #remainder #Science #senescence #socaloctopus #socialmediumaccount #time #wild
https://www.newsbeep.com/us/149128/

SoCal octopus will spend final days caring for eggs that won’t hatch

A beloved octopus is entering the last stage of her life in Long Beach,and will spend the remainder…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Wildlife #aquarium #egg #finalday #Ghost #giantpacificoctopus #life #lifecycle #natejaros #octopus #remainder #Science #senescence #socaloctopus #socialmediumaccount #time #wild
https://www.newsbeep.com/us/149128/

https://medicalxpress.com/news/2025-09-rapamycin-linked-dna-resilience-aging.html

(boomer bolstering )

Originally developed for organ transplantation to prevent immune rejection, previous research has found that, at non-#immunosuppressive doses, #rapamycin can mitigate cellular #senescence.

"rapamycin provides direct #genomicprotection in human immune cells and may support healthy aging, offer benefits after clinical #radiationexposure, and could even address risks from #cosmicradiation during extended #spacetravel."

Cellular Senescence and Brain Aging: Mechanisms, Therapeutic Strategies, and Implications for Neurodegenerative Diseases by Gaurav Gupta, 2025

In Cellular Senescence and Brain Aging, leading scientists and experts examine
how brain aging relates to senescent cells in the body. This book combines cellular biology and neuroscience, combining molecular, experimental, and translational information.

https://link.springer.com/book/10.1007/978-981-96-8873-9

@bookstodon
#books
#brain
#ageing
#senescence
#neurodegeneration

Here's another article examining a wine myth, this one that old vines make great wines. One reason there might be a correlation between old vines and great wines is that at successful vineyards they don't rip up their vines ... so the vines just get older. #wine #vineyard #grapes #alcohol #vitis #senescence #statistics https://daily.sevenfifty.com/the-science-of-old-vines/

Here's another article examining a wine myth, this one that old vines make great wines. One reason there might be a correlation between old vines and great wines is that at successful vineyards they don't rip up their vines ... so the vines just get older. #wine #vineyard #grapes #alcohol #vitis #senescence #statistics https://daily.sevenfifty.com/the-science-of-old-vines/

Here's another article examining a wine myth, this one that old vines make great wines. One reason there might be a correlation between old vines and great wines is that at successful vineyards they don't rip up their vines ... so the vines just get older. #wine #vineyard #grapes #alcohol #vitis #senescence #statistics https://daily.sevenfifty.com/the-science-of-old-vines/

Mutation accumulation theory (Evolutionary biology 🧬)

The mutation accumulation theory of aging was first proposed by Peter Medawar in 1952 as an evolutionary explanation for biological aging and the associated decline in fitness that accompanies it. Medawar used the term 'senescence' to refer to this process. The theory explains that, in the case where harmful ...

https://en.wikipedia.org/wiki/Mutation_accumulation_theory

#MutationAccumulationTheory #Genetics #Senescence #EvolutionaryBiology

Why Some #Animals Live for Only Days and Others Live for Thousands of Years
#Scientists are studying why some species live so much longer than others.
Some species of #turtles, #fishes and #salamanders, for instance, don’t show any signs of degeneration or #senescence as they grow older. If they didn’t die of predation, accidents or infectious disease, they could live extremely long lives, Magalhães says.
https://www.scientificamerican.com/article/why-some-animals-live-for-only-days-and-others-live-for-thousands-of-years/

Postdoctoral Fellow Position in Cell Stress/Senescence

UNIVERSITY OF WISCONSIN-MADISON

Come join us as postdoc in #senescence and #stress in diabetes

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95778

#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95778

Postdoctoral Fellow Position in Cell Stress/Senescence

UNIVERSITY OF WISCONSIN-MADISON

Come join us as postdoc in #senescence and #stress in diabetes

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95378

#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95378

Postdoctoral Fellow Position in Cell Stress/Senescence

UNIVERSITY OF WISCONSIN-MADISON

Come join us as postdoc in #senescence and #stress in diabetes

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95011

#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95011

A quotation from Ella Wheeler Wilcox

Let mine not be the saddest fate of all,
   To live beyond my greater self; to see
   My faculties decaying, as the tree
Stands stark and helpless while its green leaves fall.
   Let me hear rather the imperious call,
   Which all men dread, in my glad morning time,
And follow death ere I have reached my prime,
Or drunk the strengthening cordial of life’s gall.
The lightning’s stroke or the fierce tempest blast
   Which fells the green tree to the earth to-day
Is kinder than the calm that lets it last,
   Unhappy witness of its own decay.
   May no man ever look on me and say,
“She lives, but all her usefulness is past.”

Ella Wheeler Wilcox (1850-1919) American author, poet, temperance advocate, spiritualist
Poem (1882), “Uselessness,” Maurine and Other Poems (1882 ed.)

Sourcing, notes: wist.info/wilcox-ella-wheeler/…

#quote #quotes #quotation #qotd #aging #decline #gettingold #growingold #henoed #living #oldage #senescence #usefulness #uselessness #utility

Postdoctoral Fellow Position in Cell Stress/Senescence

UNIVERSITY OF WISCONSIN-MADISON

Come join us as postdoc in #senescence and #stress in diabetes

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=94419

#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=94419

Postdoctoral Fellow Position in Cell Stress/Senescence

UNIVERSITY OF WISCONSIN-MADISON

Come join us as postdoc in #senescence and #stress in diabetes

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=94353

#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=94353

Postdoctoral Fellow Position in Cell Stress/Senescence

UNIVERSITY OF WISCONSIN-MADISON

Come join us as postdoc in #senescence and #stress in diabetes

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=93839

#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=93839

Comment et quand meurent les arbres ?
https://youtu.be/PH456FnzFS0?si=1RW1lXSpRPVmApEz
#sénescence #arbre #forêt #résilience

Postdoctoral Fellow Position in Cell Stress/Senescence

UNIVERSITY OF WISCONSIN-MADISON

Come join us as postdoc in #senescence and #stress in diabetes

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=93573

#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=93573

Postdoctoral Fellow Position in Cell Stress/Senescence

UNIVERSITY OF WISCONSIN-MADISON

Come join us as postdoc in #senescence and #stress in diabetes

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=93272

#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=93272

Postdoctoral Fellow Position in Cell Stress/Senescence

UNIVERSITY OF WISCONSIN-MADISON

Come join us as postdoc in #senescence and #stress in diabetes

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=92810

#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=92810

Postdoctoral Fellow Position in Cell Stress/Senescence

UNIVERSITY OF WISCONSIN-MADISON

Come join us as postdoc in #senescence and #stress in diabetes

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=92299

#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=92299

Marcescence 😉

#MondayMotivation

Marcescent leaves add some nice colors to a winter scene 😊

#FlyFishing #Fishing #Nature #Creek #Wildlife #Hiking #Walking #Meditation #MentalHealth #Photography #Motivation #Marcescence #Senescence

SciTech Chronicles. . . . . . . . . . . . . . . . . . . . .Jan 24, 2025

https://bit.ly/stc012425

#Buses #autonomous #Imagry #Level-4 #self-generated #map #mitochondria #lymphocytes #immunotherapy #mtDNA #senescence #open-source #Cost #Security #Documentation #Customizability #Sustainability #LLM #Clone #Fudan #Meta #Alibaba #Frontier #AI #Bees #Hive #AprilTags #Pollen #foraging

Just Published!

Aging. How Science Works

https://link.springer.com/book/10.1007/978-3-031-61257-2

Aging is an unavoidable process embedded in every cell of our body. This book addresses whether aging causes diseases or vice versa and concludes with strategies for healthy aging, emphasizing the importance of living a healthy lifestyle.

Enjoy!

#Aging #HealthyAging #ChronicDiseases #Cancer #Evolution #Genetics #Epigenetics #Immunology #Senescence #Books

PPARγ attenuates cellular senescence of alveolar macrophages in asthma-COPD overlap. https://doi.org/10.1186/s12931-024-02790-6 #Aco #Asthma #Copd #Macrophages #Senescence

Leaf #senescence is essential for #crop success.
Zhou et al. offer insights into fine-tuning #leaf functional period and #grain yield formation for #wheat breeding under different #climate conditions.
https://doi.org/10.1111/jipb.13658
@wileyplantsci
#PlantSci #physiology #JIPB #CropSci #botany

CAR T cells target senescent cells, improve healthspan in mice
https://www.news-medical.net/news/20240202/CAR-T-cells-target-senescent-cells-improve-healthspan-in-mice.aspx

#CARTCells
#Senescence
#Healthspan

An #m6A-independent function of #YTHDC1: its expression delays cellular #senescence and pulmonary #fibrosis by interacting with #TopBP1 to activate ATR
https://www.embopress.org/doi/full/10.1038/s44318-023-00003-2

Is it possible to stop cellular #senescence? That’s the aim of senolytic drugs.

This #PLOSBiology Perspective looks at how discovery of the senescence-associated secretory phenotype enabled the development of #senolytics.

#aging #agingresearch

https://plos.io/3PPqepg

#PhD student studying #pathological
#senescence

Salary:
€ 2.789 - € 3.536 #PhDposition

"We are looking for an enthusiastic and ambitious PhD candidate in the Laboratory of Cellular senescence and age-related pathologies, headed by Prof. Marco Demaria to work on a project studying the contribution of #senescent cells to inflammatory and #fibrotic chronic disease. "

Required : MSc in #Biology

Closing date: August 24 CET

#UMCGroningen #UMCG #Groningen
https://werkenbijumcg.nl/-/vacatures/phd-student-studying-pathological-senescence/10419-02s00088pp

A new transparent #killifish line called klara, generated using #CRISPR/Cas9, can significantly simplify explorations of #development, #senescence, ageing and #regeneration. #ModelOrganism https://elifesciences.org/articles/81549?utm_source=mastodon&utm_medium=social&utm_campaign=organic

TFEB-dependent lysosome biogenesis is required for #senescence
by Bernadette Carroll and coworkers

Transcription factor #TFEB induces #lysosome proliferation in #senescent cells, counterbalancing reduced lysosomal efficiency and maintaining #autophagic capacity
https://www.embopress.org/doi/10.15252/embj.2022111241

#Splicing factor YBX1 regulates bone marrow stromal cell fate during aging

Reduced expression of #YBX1 in #aging #bonemarrow stromal cells induces their #senescence and bone loss due to mRNA mis-splicing

https://www.embopress.org/doi/10.15252/embj.2022111762