#antibiotic — Public Fediverse posts

https://www.europesays.com/ie/673368/ Microplastics transport toxins and antibiotic resistance across ecosystems #Antibiotic #AntibioticResistance #AntimicrobialResistance #Biofilms #chemicals #Éire #food #Genes #Health #IE #Ireland #microplastics #Pollution #Research

#Antibiotic "megacluster" discovery provides new strategy to fight #superbugs
Most #antibiotics are single bioactive molecules, and some can be thwarted with single mutations. Current situation is dire, discovery not only points to potentially new antibiotic regimen, but also entirely new strategy to once again get ahead in the microbial arms race. Block of #genes that codes for four molecules that appear to work in concert to derail a single essential metabolic pathway.
https://arstechnica.com/health/2026/06/antibiotic-megacluster-discovery-provides-new-strategy-to-fight-superbugs/

#Biofilm matrices containing filamentous phages help #Pseudomonas aeruginosa tolerate antibiotics. @tbharat_lab &co show that #nanobody disruption of #phage Pf4 #LiquidCrystalline droplets restores #antibiotic susceptibility @PLOSBiology https://plos.io/4xkd6Mw

@fabio Also due to these regulations I cannot buy antibiotic ointment when the Czech regime is depriving me of healthcare when I have an infected eczema and am afraid it will produce sepsis and I die, because antibiotic ointment ran out and when I call a dermatologist and tell I need it urgently she gives me an appointment 4 months (!!!) in the future!

In a corrupt developing 3rd world dictatorship Cambodia it is possible to buy antibiotic ointments without prescription and also dermatologist wait there is only 7-10 days, not 4 months.

I feel

e x t r e m e l y s t r o n g c o n t e m p t

towards the Czech regime.

#healthdeprivation #deprivation #czech #czechia #czechregime #czechrepublic #failedstate #contempt #regulations #overregulation #bureaucracy #overbureaucratization #healthcaresystem #healthcare #antibiotic #prescription #otc #overthecounter #ointment #eczema #infection #infected #sepsis #death #lethal #dangerous #danger #hazard #risk #eu #deathbybureaucracy #deathbyregulation #kafkaesque #humanrights #humanrightsviolation #humanrightsviolations #righttohealth #humanrighttohealth #basichumanrighttohealth

How SARPs regulate #antibiotic #biosynthesis in Streptomyces. This study combines #cryoEM structures with biochemical assays to explain how the #Streptomyces coelicolor SARP AfsR activates transcription #PLOSBiology https://plos.io/3P5DWUe

Experimental #antibiotic kills deadly #superbug, opens whole new class of #drugs
Relatively large molecule clogs a transport system, leading to lethal toxicity. In this case, the new #drug—dubbed #zosurabalpin—fights off the #GramNegative #bacterium carbapenem-resistant Acinetobacter baumannii, aka CRAB. Though it may sound obscure, it's an opportunistic, invasive #bacteria that often strikes hospitalized and critically ill patients, causing deadly #infections worldwide. https://arstechnica.com/science/2024/01/experimental-antibiotic-reveals-entirely-new-way-to-kill-drug-resistant-bacteria/

At last some good news:
Scientists hail new #antibiotic that can kill drug-resistant bacteria

#Zosurabalpin has defeated strains of pneumonia and sepsis in mice, raising hopes for human trials
https://www.theguardian.com/science/2024/jan/03/scientists-new-class-antibiotic-kill-drug-resistant-bacteria?CMP=Share_AndroidApp_Other

Scientists hail new antibiotic that can kill drug-resistant bacteria | Infectious diseases | The Guardian
https://www.theguardian.com/science/2024/jan/03/scientists-new-class-antibiotic-kill-drug-resistant-bacteria

#Antibiotic
#DrugResistantBacteria
#NewAntibiotic
#Zosurabalpin
#Sepsis
#LPS
#Lipopolysaccharide
#GramNegativeBacteria