#neurodevelopment — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #neurodevelopment, aggregated by home.social.
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Laughter Rewires Brain Architecture and Lowers Cognitive Load
Summary: A comprehensive neurodevelopmental analysis established that laughter is a complex biological engine that directly shapes early brain…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Health #braindevelopment #brainresearch #cognition #developmentalneuroscience #laughter #neural-synchrony #neurobiology #neurodevelopment #Neuroscience #TaylorandFrancisGroup
https://www.newsbeep.com/us/665180/ -
Laughter Rewires Brain Architecture and Lowers Cognitive Load
Summary: A comprehensive neurodevelopmental analysis established that laughter is a complex biological engine that directly shapes early brain…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Health #braindevelopment #brainresearch #cognition #developmentalneuroscience #laughter #neural-synchrony #neurobiology #neurodevelopment #Neuroscience #TaylorandFrancisGroup
https://www.newsbeep.com/us/665180/ -
ADHD is more than distraction or hyperactivity — it’s a brain-based condition that affects focus, organization, and impulse control. With the right treatment and support, people with ADHD can thrive. 💡
#ADHD #MentalHealth #Neurodevelopment #Telehealth #ADHDAwareness
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DATE: May 21, 2026 at 08:27AM
SOURCE: SCIENCE DAILY PSYCHOLOGY FEEDTITLE: Common pesticide linked to hidden brain damage, scientists warn
URL: https://www.sciencedaily.com/releases/2026/05/260520233218.htm
Scientists have uncovered alarming new evidence that a common insecticide may leave lasting marks on the developing brain before a child is even born. Researchers studying New York City children found that prenatal exposure to chlorpyrifos — a pesticide once widely used indoors and still used in agriculture — was linked to widespread brain abnormalities and weaker motor skills years later.
URL: https://www.sciencedaily.com/releases/2026/05/260520233218.htm
-------------------------------------------------
DAILY EMAIL DIGEST: Email [email protected] -- no subject or message needed.
Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
EMAIL DAILY DIGEST OF RSS FEEDS -- SUBSCRIBE: http://subscribe-article-digests.clinicians-exchange.org
READ ONLINE: http://read-the-rss-mega-archive.clinicians-exchange.org
It's primitive... but it works... mostly...
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #PrenatalExposure #Chlorpyrifos #PesticideWarning #BrainDevelopment #ChildHealth #EnvironmentalToxins #PrenatalHealth #Neurodevelopment #PublicHealthAlerts #MotherChildProtection
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DATE: May 21, 2026 at 08:27AM
SOURCE: SCIENCE DAILY MIND-BRAIN FEEDTITLE: Common pesticide linked to hidden brain damage, scientists warn
URL: https://www.sciencedaily.com/releases/2026/05/260520233218.htm
Scientists have uncovered alarming new evidence that a common insecticide may leave lasting marks on the developing brain before a child is even born. Researchers studying New York City children found that prenatal exposure to chlorpyrifos — a pesticide once widely used indoors and still used in agriculture — was linked to widespread brain abnormalities and weaker motor skills years later.
URL: https://www.sciencedaily.com/releases/2026/05/260520233218.htm
-------------------------------------------------
DAILY EMAIL DIGEST: Email [email protected] -- no subject or message needed.
Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
EMAIL DAILY DIGEST OF RSS FEEDS -- SUBSCRIBE: http://subscribe-article-digests.clinicians-exchange.org
READ ONLINE: http://read-the-rss-mega-archive.clinicians-exchange.org
It's primitive... but it works... mostly...
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #CommonPesticide #Chlorpyrifos #PrenatalExposure #BrainHealth #ChildDevelopment #Neurodevelopment #PublicHealth #AgricultureSafety #BrainDamageWarning #ScienceNews
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DATE: May 21, 2026 at 08:27AM
SOURCE: SCIENCE DAILY MIND-BRAIN FEEDTITLE: Common pesticide linked to hidden brain damage, scientists warn
URL: https://www.sciencedaily.com/releases/2026/05/260520233218.htm
Scientists have uncovered alarming new evidence that a common insecticide may leave lasting marks on the developing brain before a child is even born. Researchers studying New York City children found that prenatal exposure to chlorpyrifos — a pesticide once widely used indoors and still used in agriculture — was linked to widespread brain abnormalities and weaker motor skills years later.
URL: https://www.sciencedaily.com/releases/2026/05/260520233218.htm
-------------------------------------------------
DAILY EMAIL DIGEST: Email [email protected] -- no subject or message needed.
Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
EMAIL DAILY DIGEST OF RSS FEEDS -- SUBSCRIBE: http://subscribe-article-digests.clinicians-exchange.org
READ ONLINE: http://read-the-rss-mega-archive.clinicians-exchange.org
It's primitive... but it works... mostly...
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #CommonPesticide #Chlorpyrifos #PrenatalExposure #BrainHealth #ChildDevelopment #Neurodevelopment #PublicHealth #AgricultureSafety #BrainDamageWarning #ScienceNews
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DATE: May 21, 2026 at 08:27AM
SOURCE: SCIENCE DAILY MIND-BRAIN FEEDTITLE: Common pesticide linked to hidden brain damage, scientists warn
URL: https://www.sciencedaily.com/releases/2026/05/260520233218.htm
Scientists have uncovered alarming new evidence that a common insecticide may leave lasting marks on the developing brain before a child is even born. Researchers studying New York City children found that prenatal exposure to chlorpyrifos — a pesticide once widely used indoors and still used in agriculture — was linked to widespread brain abnormalities and weaker motor skills years later.
URL: https://www.sciencedaily.com/releases/2026/05/260520233218.htm
-------------------------------------------------
DAILY EMAIL DIGEST: Email [email protected] -- no subject or message needed.
Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
EMAIL DAILY DIGEST OF RSS FEEDS -- SUBSCRIBE: http://subscribe-article-digests.clinicians-exchange.org
READ ONLINE: http://read-the-rss-mega-archive.clinicians-exchange.org
It's primitive... but it works... mostly...
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #CommonPesticide #Chlorpyrifos #PrenatalExposure #BrainHealth #ChildDevelopment #Neurodevelopment #PublicHealth #AgricultureSafety #BrainDamageWarning #ScienceNews
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DATE: May 18, 2026 at 08:00PM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Scientists discover that dopamine receptors act as traffic signals to guide migrating brain cells
The assembly of a healthy brain requires new cells to travel incredibly long distances to arrive at their correct final destinations. A recent laboratory mouse study reveals that dopamine receptors located on stationary support cells act remarkably like traffic signals, slowing down migrating neurons so they settle in the correct areas. These findings, published in the European Journal of Neuroscience, suggest that early disruptions to dopamine signaling could permanently alter brain wiring and network connectivity.
Lead investigator Anne-Gaëlle Toutain, a neurobiology researcher at the Fer à Moulin Institute in Paris, conducted the study alongside corresponding author Christine Métin and several other academic collaborators. The team focused their efforts on analyzing the cerebral cortex, the wrinkled outer blanket of the brain responsible for higher cognitive functions. The cellular makeup of this cortical region must be perfectly balanced for the brain as a whole to function properly.
Most individual cells in the cortex are excitatory neurons, which routinely send active signaling impulses to other parts of the mammalian brain. To prevent the brain from becoming hyperactive or overwhelmed, the cortex also heavily relies on inhibitory cells known as interneurons. These smaller interneurons act as a vital cellular braking system, periodically releasing chemicals that calm overall network activity.
Excitatory neurons are born locally in the developing cortex, but the inhibitory interneurons face a much harder and more demanding physical journey. They originally emerge deep inside the core of the embryonic brain in a structure known to developmental biologists as the medial ganglionic eminence. From there, they must migrate great distances outward and upward to populate the developing outer cortex.
Neuroscientists have recognized for years that this brain cell migration is a highly choreographed and delicate biological process. To arrive safely at the correct destination, migrating interneurons must continuously read chemical cues dispersed across their cellular environment. Among these developmental cues is dopamine, a common brain chemical mostly famous for driving feelings of reward and motivation in adult brains.
Biologists possess evidence showing that dopamine is actually present very early in fetal development, arising long before the brain is fully wired or functional. Developing embryonic cells detect this chemical using specific surface proteins commonly called D1 dopamine receptors. Toutain and her entire research team wanted to find out exactly how these sensory receptors physically guide the long-distance journey of migrating interneurons.
Research into fetal dopamine signaling carries a wide range of tangible public health implications. For instance, human babies exposed to illicit drugs like cocaine in the womb fairly often suffer from smaller head sizes and a heightened biological risk of seizures. Because addictive substances directly bombard the dopamine system, they alter the delicate chemical balance needed to correctly wire the vulnerable embryonic brain.
To accurately map the cellular terrain, the researchers engineered laboratory mice to produce a glowing fluorescent protein wherever a D1 receptor was actively operating. This built-in visual marker allowed the scientists to directly map the precise physical locations of the dopamine-sensing cells in the fetal brain. They quickly observed a strangely heavy concentration of D1 receptors clustered tight in the deepest layers of the newly developing cortex.
These unique receptor-heavy cells formed a noticeably dense, continuous cellular layer right along the physical path that the migrating interneurons usually take toward the surface. The team also used analytical chemistry techniques to quantitatively confirm that raw dopamine was floating freely in these exact regions. This verified that the deeply layered cortical cells were actively responding to the chemical while the interneurons traveled aggressively past them.
To see precisely how the D1 receptor influences this cellular movement, the researchers set up isolated cell cultures in flat laboratory dishes. They extracted migrating interneurons and placed them on top of an artificial base layer composed entirely of stationary cortex cells. The research team also deployed highly targeted genetic tools to selectively delete the D1 receptor from the different tissues before ultimately combining them.
This mixing and matching allowed the researchers to watch exactly what happened when the receptor was entirely missing from the migrating cell, the stationary cell, or both cells simultaneously. They tracked the tiny movements of the cells over twenty consecutive hours using advanced time-lapse video microscopy. The resulting footage of this specific biological experiment defied initial scientific expectations about how the brain cells normally behave.
Genetically removing the D1 receptor from the migrating interneurons themselves barely changed their typical travel habits. However, when the researchers deleted the sensory receptor from the stationary cortex cells, the migrating interneurons suddenly began moving at incredibly fast speeds. The migrating cells took noticeably shorter rest pauses and dashed rapidly forward with much greater frequency than their completely unmodified counterparts.
This type of strange phenomenon is known in developmental biology as a non-cell-autonomous effect. A specific genetic alteration in one individual support cell essentially dictates the physical movement behavior of a completely different brain cell. The active D1 receptors on the stationary cortex cells normally act exactly like a textured terrain, heavily slowing down the migrating neurons to a far more manageable physiological pace.
To see if this fast-paced embryonic migration permanently altered the functional anatomy of the brain, the team closely examined fully grown adult mice. They engineered a dedicated group of test mice to lack D1 receptors exclusively in their stationary cortex cells. Because the migrating interneurons in these mice retained completely normal genetics, any subsequent structural changes would absolutely have to stem from the altered cellular terrain.
The researchers counted two distinct biological populations of interneurons to see where they eventually settled across the mature brain. One population consisted of somatostatin-producing cells, which usually migrate very early in the general timeline of embryonic development. The other group was made up of parvalbumin-producing cells, which generally migrate a few days later in the normal fetal maturation schedule.
Because they moved entirely too fast across the slippery cellular terrain, both subsets of cells severely overshot their originally intended marks. The early somatostatin cells piled up in abnormally high numbers at the extreme front and middle edges of the fully formed cortex. The later parvalbumin cells essentially accumulated in the dense sensory regions at the remote back of the completed brain.
Finally, the researchers evaluated mice missing the key D1 receptor entirely, possessing genetic instructions where absolutely no cells in their bodies could ever detect targeted dopamine signals. This profound genetic model closely resembles the biological reality of a severe organism-wide mutation. Without the primary D1 receptor guiding early cortical growth, the overall physical volume of the cerebral cortex shrank dramatically by roughly a full quarter.
Despite experiencing this massive reduction in total brain volume, the interneurons still clustered in the exact same abnormal architectural patterns at the outer edges of the cortex. This conclusive phase of the study showed that the physical environment created by the cortex cells overwhelmingly dominates the cellular migration process. Even in a stunted biological brain, the missing cellular speed bumps sent the migrating cells flying blindly toward the outermost boundaries.
There are still a few missing experimental pieces to this fascinating neurobiological puzzle. The exact biological mechanism that the stationary cortex cells use to slow down the sweeping interneurons remains unknown to the scientific community at large. The active dopamine receptors might alter the overall physical shape of the support cells, or they might subtly change how sticky or slippery the cellular surfaces eventually become.
Future researchers will definitively need to untangle the hidden physical and chemical interactions occurring at the exact microscopic locations where these two cell types frequently touch. Uncovering these hidden mechanisms could eventually shed bright light on a wide variety of poorly understood developmental disorders. Unusually high or low densities of local interneurons are an established feature in the brains of some patients diagnosed medically with schizophrenia and autism.
If fetal dopamine signaling becomes disturbed by inherited genetic traits or external environmental factors, it could eventually lead to these permanent, lifelong structural shifts. The latest findings illustrate how such a seemingly tiny molecular event can ripple outward to reshape the entire physical brain architecture. Understanding this early cellular journey acts as a foundational jumping-off point toward ultimately treating broader neurodevelopmental disorders down the line.
The study, “Ablation of the D1 Dopamine Receptor Alters the Migration and the Cortical Distribution of MGE-Derived Inhibitory Interneurons by a Preponderant Non–Cell-Autonomous Effect,” was authored by Anne-Gaëlle Toutain, Sophie Scotto-Lomassese, Aude Muzerelle, Julien Puech, Ariane Fayad, Anne Roumier, Denis Hervé, and Christine Métin.
-------------------------------------------------
DAILY EMAIL DIGEST: Email [email protected] -- no subject or message needed.
Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
EMAIL DAILY DIGEST OF RSS FEEDS -- SUBSCRIBE: http://subscribe-article-digests.clinicians-exchange.org
READ ONLINE: http://read-the-rss-mega-archive.clinicians-exchange.org
It's primitive... but it works... mostly...
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #DopamineSignals #InterneuronsMigration #CorticalDevelopment #D1Receptors #Neurobiology #BrainWiring #NonCellAutonomous #NeuroscienceResearch #NeuroDevelopment #BrainConnectivity
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DATE: May 18, 2026 at 08:00PM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Scientists discover that dopamine receptors act as traffic signals to guide migrating brain cells
The assembly of a healthy brain requires new cells to travel incredibly long distances to arrive at their correct final destinations. A recent laboratory mouse study reveals that dopamine receptors located on stationary support cells act remarkably like traffic signals, slowing down migrating neurons so they settle in the correct areas. These findings, published in the European Journal of Neuroscience, suggest that early disruptions to dopamine signaling could permanently alter brain wiring and network connectivity.
Lead investigator Anne-Gaëlle Toutain, a neurobiology researcher at the Fer à Moulin Institute in Paris, conducted the study alongside corresponding author Christine Métin and several other academic collaborators. The team focused their efforts on analyzing the cerebral cortex, the wrinkled outer blanket of the brain responsible for higher cognitive functions. The cellular makeup of this cortical region must be perfectly balanced for the brain as a whole to function properly.
Most individual cells in the cortex are excitatory neurons, which routinely send active signaling impulses to other parts of the mammalian brain. To prevent the brain from becoming hyperactive or overwhelmed, the cortex also heavily relies on inhibitory cells known as interneurons. These smaller interneurons act as a vital cellular braking system, periodically releasing chemicals that calm overall network activity.
Excitatory neurons are born locally in the developing cortex, but the inhibitory interneurons face a much harder and more demanding physical journey. They originally emerge deep inside the core of the embryonic brain in a structure known to developmental biologists as the medial ganglionic eminence. From there, they must migrate great distances outward and upward to populate the developing outer cortex.
Neuroscientists have recognized for years that this brain cell migration is a highly choreographed and delicate biological process. To arrive safely at the correct destination, migrating interneurons must continuously read chemical cues dispersed across their cellular environment. Among these developmental cues is dopamine, a common brain chemical mostly famous for driving feelings of reward and motivation in adult brains.
Biologists possess evidence showing that dopamine is actually present very early in fetal development, arising long before the brain is fully wired or functional. Developing embryonic cells detect this chemical using specific surface proteins commonly called D1 dopamine receptors. Toutain and her entire research team wanted to find out exactly how these sensory receptors physically guide the long-distance journey of migrating interneurons.
Research into fetal dopamine signaling carries a wide range of tangible public health implications. For instance, human babies exposed to illicit drugs like cocaine in the womb fairly often suffer from smaller head sizes and a heightened biological risk of seizures. Because addictive substances directly bombard the dopamine system, they alter the delicate chemical balance needed to correctly wire the vulnerable embryonic brain.
To accurately map the cellular terrain, the researchers engineered laboratory mice to produce a glowing fluorescent protein wherever a D1 receptor was actively operating. This built-in visual marker allowed the scientists to directly map the precise physical locations of the dopamine-sensing cells in the fetal brain. They quickly observed a strangely heavy concentration of D1 receptors clustered tight in the deepest layers of the newly developing cortex.
These unique receptor-heavy cells formed a noticeably dense, continuous cellular layer right along the physical path that the migrating interneurons usually take toward the surface. The team also used analytical chemistry techniques to quantitatively confirm that raw dopamine was floating freely in these exact regions. This verified that the deeply layered cortical cells were actively responding to the chemical while the interneurons traveled aggressively past them.
To see precisely how the D1 receptor influences this cellular movement, the researchers set up isolated cell cultures in flat laboratory dishes. They extracted migrating interneurons and placed them on top of an artificial base layer composed entirely of stationary cortex cells. The research team also deployed highly targeted genetic tools to selectively delete the D1 receptor from the different tissues before ultimately combining them.
This mixing and matching allowed the researchers to watch exactly what happened when the receptor was entirely missing from the migrating cell, the stationary cell, or both cells simultaneously. They tracked the tiny movements of the cells over twenty consecutive hours using advanced time-lapse video microscopy. The resulting footage of this specific biological experiment defied initial scientific expectations about how the brain cells normally behave.
Genetically removing the D1 receptor from the migrating interneurons themselves barely changed their typical travel habits. However, when the researchers deleted the sensory receptor from the stationary cortex cells, the migrating interneurons suddenly began moving at incredibly fast speeds. The migrating cells took noticeably shorter rest pauses and dashed rapidly forward with much greater frequency than their completely unmodified counterparts.
This type of strange phenomenon is known in developmental biology as a non-cell-autonomous effect. A specific genetic alteration in one individual support cell essentially dictates the physical movement behavior of a completely different brain cell. The active D1 receptors on the stationary cortex cells normally act exactly like a textured terrain, heavily slowing down the migrating neurons to a far more manageable physiological pace.
To see if this fast-paced embryonic migration permanently altered the functional anatomy of the brain, the team closely examined fully grown adult mice. They engineered a dedicated group of test mice to lack D1 receptors exclusively in their stationary cortex cells. Because the migrating interneurons in these mice retained completely normal genetics, any subsequent structural changes would absolutely have to stem from the altered cellular terrain.
The researchers counted two distinct biological populations of interneurons to see where they eventually settled across the mature brain. One population consisted of somatostatin-producing cells, which usually migrate very early in the general timeline of embryonic development. The other group was made up of parvalbumin-producing cells, which generally migrate a few days later in the normal fetal maturation schedule.
Because they moved entirely too fast across the slippery cellular terrain, both subsets of cells severely overshot their originally intended marks. The early somatostatin cells piled up in abnormally high numbers at the extreme front and middle edges of the fully formed cortex. The later parvalbumin cells essentially accumulated in the dense sensory regions at the remote back of the completed brain.
Finally, the researchers evaluated mice missing the key D1 receptor entirely, possessing genetic instructions where absolutely no cells in their bodies could ever detect targeted dopamine signals. This profound genetic model closely resembles the biological reality of a severe organism-wide mutation. Without the primary D1 receptor guiding early cortical growth, the overall physical volume of the cerebral cortex shrank dramatically by roughly a full quarter.
Despite experiencing this massive reduction in total brain volume, the interneurons still clustered in the exact same abnormal architectural patterns at the outer edges of the cortex. This conclusive phase of the study showed that the physical environment created by the cortex cells overwhelmingly dominates the cellular migration process. Even in a stunted biological brain, the missing cellular speed bumps sent the migrating cells flying blindly toward the outermost boundaries.
There are still a few missing experimental pieces to this fascinating neurobiological puzzle. The exact biological mechanism that the stationary cortex cells use to slow down the sweeping interneurons remains unknown to the scientific community at large. The active dopamine receptors might alter the overall physical shape of the support cells, or they might subtly change how sticky or slippery the cellular surfaces eventually become.
Future researchers will definitively need to untangle the hidden physical and chemical interactions occurring at the exact microscopic locations where these two cell types frequently touch. Uncovering these hidden mechanisms could eventually shed bright light on a wide variety of poorly understood developmental disorders. Unusually high or low densities of local interneurons are an established feature in the brains of some patients diagnosed medically with schizophrenia and autism.
If fetal dopamine signaling becomes disturbed by inherited genetic traits or external environmental factors, it could eventually lead to these permanent, lifelong structural shifts. The latest findings illustrate how such a seemingly tiny molecular event can ripple outward to reshape the entire physical brain architecture. Understanding this early cellular journey acts as a foundational jumping-off point toward ultimately treating broader neurodevelopmental disorders down the line.
The study, “Ablation of the D1 Dopamine Receptor Alters the Migration and the Cortical Distribution of MGE-Derived Inhibitory Interneurons by a Preponderant Non–Cell-Autonomous Effect,” was authored by Anne-Gaëlle Toutain, Sophie Scotto-Lomassese, Aude Muzerelle, Julien Puech, Ariane Fayad, Anne Roumier, Denis Hervé, and Christine Métin.
-------------------------------------------------
DAILY EMAIL DIGEST: Email [email protected] -- no subject or message needed.
Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
EMAIL DAILY DIGEST OF RSS FEEDS -- SUBSCRIBE: http://subscribe-article-digests.clinicians-exchange.org
READ ONLINE: http://read-the-rss-mega-archive.clinicians-exchange.org
It's primitive... but it works... mostly...
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #DopamineSignals #InterneuronsMigration #CorticalDevelopment #D1Receptors #Neurobiology #BrainWiring #NonCellAutonomous #NeuroscienceResearch #NeuroDevelopment #BrainConnectivity
-
DATE: May 18, 2026 at 08:00PM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Scientists discover that dopamine receptors act as traffic signals to guide migrating brain cells
The assembly of a healthy brain requires new cells to travel incredibly long distances to arrive at their correct final destinations. A recent laboratory mouse study reveals that dopamine receptors located on stationary support cells act remarkably like traffic signals, slowing down migrating neurons so they settle in the correct areas. These findings, published in the European Journal of Neuroscience, suggest that early disruptions to dopamine signaling could permanently alter brain wiring and network connectivity.
Lead investigator Anne-Gaëlle Toutain, a neurobiology researcher at the Fer à Moulin Institute in Paris, conducted the study alongside corresponding author Christine Métin and several other academic collaborators. The team focused their efforts on analyzing the cerebral cortex, the wrinkled outer blanket of the brain responsible for higher cognitive functions. The cellular makeup of this cortical region must be perfectly balanced for the brain as a whole to function properly.
Most individual cells in the cortex are excitatory neurons, which routinely send active signaling impulses to other parts of the mammalian brain. To prevent the brain from becoming hyperactive or overwhelmed, the cortex also heavily relies on inhibitory cells known as interneurons. These smaller interneurons act as a vital cellular braking system, periodically releasing chemicals that calm overall network activity.
Excitatory neurons are born locally in the developing cortex, but the inhibitory interneurons face a much harder and more demanding physical journey. They originally emerge deep inside the core of the embryonic brain in a structure known to developmental biologists as the medial ganglionic eminence. From there, they must migrate great distances outward and upward to populate the developing outer cortex.
Neuroscientists have recognized for years that this brain cell migration is a highly choreographed and delicate biological process. To arrive safely at the correct destination, migrating interneurons must continuously read chemical cues dispersed across their cellular environment. Among these developmental cues is dopamine, a common brain chemical mostly famous for driving feelings of reward and motivation in adult brains.
Biologists possess evidence showing that dopamine is actually present very early in fetal development, arising long before the brain is fully wired or functional. Developing embryonic cells detect this chemical using specific surface proteins commonly called D1 dopamine receptors. Toutain and her entire research team wanted to find out exactly how these sensory receptors physically guide the long-distance journey of migrating interneurons.
Research into fetal dopamine signaling carries a wide range of tangible public health implications. For instance, human babies exposed to illicit drugs like cocaine in the womb fairly often suffer from smaller head sizes and a heightened biological risk of seizures. Because addictive substances directly bombard the dopamine system, they alter the delicate chemical balance needed to correctly wire the vulnerable embryonic brain.
To accurately map the cellular terrain, the researchers engineered laboratory mice to produce a glowing fluorescent protein wherever a D1 receptor was actively operating. This built-in visual marker allowed the scientists to directly map the precise physical locations of the dopamine-sensing cells in the fetal brain. They quickly observed a strangely heavy concentration of D1 receptors clustered tight in the deepest layers of the newly developing cortex.
These unique receptor-heavy cells formed a noticeably dense, continuous cellular layer right along the physical path that the migrating interneurons usually take toward the surface. The team also used analytical chemistry techniques to quantitatively confirm that raw dopamine was floating freely in these exact regions. This verified that the deeply layered cortical cells were actively responding to the chemical while the interneurons traveled aggressively past them.
To see precisely how the D1 receptor influences this cellular movement, the researchers set up isolated cell cultures in flat laboratory dishes. They extracted migrating interneurons and placed them on top of an artificial base layer composed entirely of stationary cortex cells. The research team also deployed highly targeted genetic tools to selectively delete the D1 receptor from the different tissues before ultimately combining them.
This mixing and matching allowed the researchers to watch exactly what happened when the receptor was entirely missing from the migrating cell, the stationary cell, or both cells simultaneously. They tracked the tiny movements of the cells over twenty consecutive hours using advanced time-lapse video microscopy. The resulting footage of this specific biological experiment defied initial scientific expectations about how the brain cells normally behave.
Genetically removing the D1 receptor from the migrating interneurons themselves barely changed their typical travel habits. However, when the researchers deleted the sensory receptor from the stationary cortex cells, the migrating interneurons suddenly began moving at incredibly fast speeds. The migrating cells took noticeably shorter rest pauses and dashed rapidly forward with much greater frequency than their completely unmodified counterparts.
This type of strange phenomenon is known in developmental biology as a non-cell-autonomous effect. A specific genetic alteration in one individual support cell essentially dictates the physical movement behavior of a completely different brain cell. The active D1 receptors on the stationary cortex cells normally act exactly like a textured terrain, heavily slowing down the migrating neurons to a far more manageable physiological pace.
To see if this fast-paced embryonic migration permanently altered the functional anatomy of the brain, the team closely examined fully grown adult mice. They engineered a dedicated group of test mice to lack D1 receptors exclusively in their stationary cortex cells. Because the migrating interneurons in these mice retained completely normal genetics, any subsequent structural changes would absolutely have to stem from the altered cellular terrain.
The researchers counted two distinct biological populations of interneurons to see where they eventually settled across the mature brain. One population consisted of somatostatin-producing cells, which usually migrate very early in the general timeline of embryonic development. The other group was made up of parvalbumin-producing cells, which generally migrate a few days later in the normal fetal maturation schedule.
Because they moved entirely too fast across the slippery cellular terrain, both subsets of cells severely overshot their originally intended marks. The early somatostatin cells piled up in abnormally high numbers at the extreme front and middle edges of the fully formed cortex. The later parvalbumin cells essentially accumulated in the dense sensory regions at the remote back of the completed brain.
Finally, the researchers evaluated mice missing the key D1 receptor entirely, possessing genetic instructions where absolutely no cells in their bodies could ever detect targeted dopamine signals. This profound genetic model closely resembles the biological reality of a severe organism-wide mutation. Without the primary D1 receptor guiding early cortical growth, the overall physical volume of the cerebral cortex shrank dramatically by roughly a full quarter.
Despite experiencing this massive reduction in total brain volume, the interneurons still clustered in the exact same abnormal architectural patterns at the outer edges of the cortex. This conclusive phase of the study showed that the physical environment created by the cortex cells overwhelmingly dominates the cellular migration process. Even in a stunted biological brain, the missing cellular speed bumps sent the migrating cells flying blindly toward the outermost boundaries.
There are still a few missing experimental pieces to this fascinating neurobiological puzzle. The exact biological mechanism that the stationary cortex cells use to slow down the sweeping interneurons remains unknown to the scientific community at large. The active dopamine receptors might alter the overall physical shape of the support cells, or they might subtly change how sticky or slippery the cellular surfaces eventually become.
Future researchers will definitively need to untangle the hidden physical and chemical interactions occurring at the exact microscopic locations where these two cell types frequently touch. Uncovering these hidden mechanisms could eventually shed bright light on a wide variety of poorly understood developmental disorders. Unusually high or low densities of local interneurons are an established feature in the brains of some patients diagnosed medically with schizophrenia and autism.
If fetal dopamine signaling becomes disturbed by inherited genetic traits or external environmental factors, it could eventually lead to these permanent, lifelong structural shifts. The latest findings illustrate how such a seemingly tiny molecular event can ripple outward to reshape the entire physical brain architecture. Understanding this early cellular journey acts as a foundational jumping-off point toward ultimately treating broader neurodevelopmental disorders down the line.
The study, “Ablation of the D1 Dopamine Receptor Alters the Migration and the Cortical Distribution of MGE-Derived Inhibitory Interneurons by a Preponderant Non–Cell-Autonomous Effect,” was authored by Anne-Gaëlle Toutain, Sophie Scotto-Lomassese, Aude Muzerelle, Julien Puech, Ariane Fayad, Anne Roumier, Denis Hervé, and Christine Métin.
-------------------------------------------------
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#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #DopamineSignals #InterneuronsMigration #CorticalDevelopment #D1Receptors #Neurobiology #BrainWiring #NonCellAutonomous #NeuroscienceResearch #NeuroDevelopment #BrainConnectivity
-
DATE: May 16, 2026 at 02:00PM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Unpredictable childhoods may hinder a young adult’s ability to take positive risks
A 7-year longitudinal study found that adolescents who experienced more unpredictable life events tend to show higher levels of activation in the frontoparietal region of the brain during a cognitive control task. Because a maturing brain should require less effort to complete these tasks, this higher activation suggests a less efficient brain network. In turn, this inefficiency was associated with a lower willingness to take positive social risks (e.g., exploring a new career, voicing an unpopular opinion, starting a conversation) in young adulthood. The paper was published in Social Cognitive and Affective Neuroscience.
Positive social risks are situations in which a person takes a chance in social life in order to create a positive outcome or long-term benefit. They include actions such as starting a conversation, apologizing first, asking for help, offering help, admitting a mistake, or expressing honest feelings. These actions are “risks” because the other person may reject us, criticize us, misunderstand us, or fail to respond warmly. They are “positive” because they can lead to trust, friendship, cooperation, forgiveness, learning, and stronger relationships.
For example, inviting a new classmate to join a group may feel uncomfortable, but it can help that person feel accepted. Telling the truth respectfully can also be a positive social risk because it may improve communication even if it feels difficult at first. Positive social risks are important because many valuable relationships and opportunities begin with someone being brave enough to act first. They also help people develop confidence, empathy, and social skills. Without positive social risks, people avoid rejection but also miss chances for connection, career advancement, and personal growth.
Study author Morgan Lindenmuth and his colleagues explored how unpredictable negative life events in childhood may be associated with positive social risk taking in adolescence and early adulthood through changes in cognitive development. Studies indicate that experiencing a chaotic environment in childhood is associated with a “fast” life strategy, leading to higher aggression and harmful risk-taking. The authors of this study hypothesized that an unpredictable environment may also reduce positive risk taking by altering how the developing brain wires its decision-making centers.
They conducted a longitudinal study that followed 167 adolescents from a southeastern state in the United States for 7 years. Participating adolescents were 13-14 years old at the start of the study. 78% of them identified as White.
During the study period, participants and their parents completed self-report questionnaires, and the teens completed behavioral and neuroimaging tasks once a year at the university offices of the study authors. Parents completed an assessment of negative life events in their children’s lives during the first 4 years of the study (using the Child and Adolescent Survey of Experiences). To measure “unpredictability,” the researchers specifically focused on four events related to instability: changes in cohabitation (someone moving in or out), parental job loss, and changes in residence (moving).
At these annual check-ins, study participants also completed an assessment of cognitive control (the Multi-Source Interference Task) while undergoing functional magnetic resonance imaging (fMRI). The task required them to view three digits and press a button to indicate which one was different, testing their ability to ignore distractions and focus. When the study participants reached young adulthood (between 18 and 21 years old), they completed an assessment measuring their likelihood of engaging in positive social risk taking (the Domain Specific Risk-Taking Scale).
The researchers used statistical modeling to track the adolescents’ brain development over the four years of fMRI scans. The results showed that, generally, frontoparietal activation decreased as the teens got older, reflecting a maturing, more efficient brain network. However, adolescents who experienced more unpredictable life events during this period had higher levels of frontoparietal activation by age 17, suggesting their cognitive control processing was less efficient than their peers.
In turn, this higher brain activation at age 17 was associated with slightly lower positive social risk taking when participants were between 18 and 21 years old.
The study authors tested a statistical mediation model proposing that unpredictability (as reported by parents when participants were 14-17 years old) hinders the development of the brain’s cognitive control centers, leading to increased, inefficient activation in the frontoparietal region at age 17. In turn, this less mature brain functioning leads to a lower willingness to take positive social risks in young adulthood (18-21 years of age). The results showed a significant “indirect effect,” meaning this chain of events is highly plausible.
“The findings have important implications for understanding the antecedents of risk-taking behaviors by highlighting the role of neurocognitive functioning in linking environmental unpredictability to positive social risk outcomes,” the study authors concluded.
The study contributes to the scientific understanding of how childhood experiences physically alter the brain and shape personality characteristics observed in adulthood. However, it should be noted that the observed associations were relatively weak, and simple bivariate correlations did not indicate a direct, straight-line association between unpredictability in adolescence and positive social risk taking in young adulthood (the connection only appeared when factoring in the brain development data).
The paper, “Environmental Unpredictability Predicts Positive Social Risk Taking through Neural Cognitive Control,” was authored by Morgan Lindenmuth, Celina Meyer, Jacob Lee, Laurence Steinberg, Brooks Casas, and Jungmeen Kim-Spoon.
-------------------------------------------------
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-------------------------------------------------
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-
DATE: May 16, 2026 at 02:00PM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Unpredictable childhoods may hinder a young adult’s ability to take positive risks
A 7-year longitudinal study found that adolescents who experienced more unpredictable life events tend to show higher levels of activation in the frontoparietal region of the brain during a cognitive control task. Because a maturing brain should require less effort to complete these tasks, this higher activation suggests a less efficient brain network. In turn, this inefficiency was associated with a lower willingness to take positive social risks (e.g., exploring a new career, voicing an unpopular opinion, starting a conversation) in young adulthood. The paper was published in Social Cognitive and Affective Neuroscience.
Positive social risks are situations in which a person takes a chance in social life in order to create a positive outcome or long-term benefit. They include actions such as starting a conversation, apologizing first, asking for help, offering help, admitting a mistake, or expressing honest feelings. These actions are “risks” because the other person may reject us, criticize us, misunderstand us, or fail to respond warmly. They are “positive” because they can lead to trust, friendship, cooperation, forgiveness, learning, and stronger relationships.
For example, inviting a new classmate to join a group may feel uncomfortable, but it can help that person feel accepted. Telling the truth respectfully can also be a positive social risk because it may improve communication even if it feels difficult at first. Positive social risks are important because many valuable relationships and opportunities begin with someone being brave enough to act first. They also help people develop confidence, empathy, and social skills. Without positive social risks, people avoid rejection but also miss chances for connection, career advancement, and personal growth.
Study author Morgan Lindenmuth and his colleagues explored how unpredictable negative life events in childhood may be associated with positive social risk taking in adolescence and early adulthood through changes in cognitive development. Studies indicate that experiencing a chaotic environment in childhood is associated with a “fast” life strategy, leading to higher aggression and harmful risk-taking. The authors of this study hypothesized that an unpredictable environment may also reduce positive risk taking by altering how the developing brain wires its decision-making centers.
They conducted a longitudinal study that followed 167 adolescents from a southeastern state in the United States for 7 years. Participating adolescents were 13-14 years old at the start of the study. 78% of them identified as White.
During the study period, participants and their parents completed self-report questionnaires, and the teens completed behavioral and neuroimaging tasks once a year at the university offices of the study authors. Parents completed an assessment of negative life events in their children’s lives during the first 4 years of the study (using the Child and Adolescent Survey of Experiences). To measure “unpredictability,” the researchers specifically focused on four events related to instability: changes in cohabitation (someone moving in or out), parental job loss, and changes in residence (moving).
At these annual check-ins, study participants also completed an assessment of cognitive control (the Multi-Source Interference Task) while undergoing functional magnetic resonance imaging (fMRI). The task required them to view three digits and press a button to indicate which one was different, testing their ability to ignore distractions and focus. When the study participants reached young adulthood (between 18 and 21 years old), they completed an assessment measuring their likelihood of engaging in positive social risk taking (the Domain Specific Risk-Taking Scale).
The researchers used statistical modeling to track the adolescents’ brain development over the four years of fMRI scans. The results showed that, generally, frontoparietal activation decreased as the teens got older, reflecting a maturing, more efficient brain network. However, adolescents who experienced more unpredictable life events during this period had higher levels of frontoparietal activation by age 17, suggesting their cognitive control processing was less efficient than their peers.
In turn, this higher brain activation at age 17 was associated with slightly lower positive social risk taking when participants were between 18 and 21 years old.
The study authors tested a statistical mediation model proposing that unpredictability (as reported by parents when participants were 14-17 years old) hinders the development of the brain’s cognitive control centers, leading to increased, inefficient activation in the frontoparietal region at age 17. In turn, this less mature brain functioning leads to a lower willingness to take positive social risks in young adulthood (18-21 years of age). The results showed a significant “indirect effect,” meaning this chain of events is highly plausible.
“The findings have important implications for understanding the antecedents of risk-taking behaviors by highlighting the role of neurocognitive functioning in linking environmental unpredictability to positive social risk outcomes,” the study authors concluded.
The study contributes to the scientific understanding of how childhood experiences physically alter the brain and shape personality characteristics observed in adulthood. However, it should be noted that the observed associations were relatively weak, and simple bivariate correlations did not indicate a direct, straight-line association between unpredictability in adolescence and positive social risk taking in young adulthood (the connection only appeared when factoring in the brain development data).
The paper, “Environmental Unpredictability Predicts Positive Social Risk Taking through Neural Cognitive Control,” was authored by Morgan Lindenmuth, Celina Meyer, Jacob Lee, Laurence Steinberg, Brooks Casas, and Jungmeen Kim-Spoon.
-------------------------------------------------
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NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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It's primitive... but it works... mostly...
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #UnpredictableChildhoods #PositiveSocialRisks #CognitiveControl #Frontoparietal #Neuroscience #BrainDevelopment #AdolescentToAdult #RiskTaking #Neurodevelopment #SocialCognition
-
DATE: May 16, 2026 at 02:00PM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Unpredictable childhoods may hinder a young adult’s ability to take positive risks
A 7-year longitudinal study found that adolescents who experienced more unpredictable life events tend to show higher levels of activation in the frontoparietal region of the brain during a cognitive control task. Because a maturing brain should require less effort to complete these tasks, this higher activation suggests a less efficient brain network. In turn, this inefficiency was associated with a lower willingness to take positive social risks (e.g., exploring a new career, voicing an unpopular opinion, starting a conversation) in young adulthood. The paper was published in Social Cognitive and Affective Neuroscience.
Positive social risks are situations in which a person takes a chance in social life in order to create a positive outcome or long-term benefit. They include actions such as starting a conversation, apologizing first, asking for help, offering help, admitting a mistake, or expressing honest feelings. These actions are “risks” because the other person may reject us, criticize us, misunderstand us, or fail to respond warmly. They are “positive” because they can lead to trust, friendship, cooperation, forgiveness, learning, and stronger relationships.
For example, inviting a new classmate to join a group may feel uncomfortable, but it can help that person feel accepted. Telling the truth respectfully can also be a positive social risk because it may improve communication even if it feels difficult at first. Positive social risks are important because many valuable relationships and opportunities begin with someone being brave enough to act first. They also help people develop confidence, empathy, and social skills. Without positive social risks, people avoid rejection but also miss chances for connection, career advancement, and personal growth.
Study author Morgan Lindenmuth and his colleagues explored how unpredictable negative life events in childhood may be associated with positive social risk taking in adolescence and early adulthood through changes in cognitive development. Studies indicate that experiencing a chaotic environment in childhood is associated with a “fast” life strategy, leading to higher aggression and harmful risk-taking. The authors of this study hypothesized that an unpredictable environment may also reduce positive risk taking by altering how the developing brain wires its decision-making centers.
They conducted a longitudinal study that followed 167 adolescents from a southeastern state in the United States for 7 years. Participating adolescents were 13-14 years old at the start of the study. 78% of them identified as White.
During the study period, participants and their parents completed self-report questionnaires, and the teens completed behavioral and neuroimaging tasks once a year at the university offices of the study authors. Parents completed an assessment of negative life events in their children’s lives during the first 4 years of the study (using the Child and Adolescent Survey of Experiences). To measure “unpredictability,” the researchers specifically focused on four events related to instability: changes in cohabitation (someone moving in or out), parental job loss, and changes in residence (moving).
At these annual check-ins, study participants also completed an assessment of cognitive control (the Multi-Source Interference Task) while undergoing functional magnetic resonance imaging (fMRI). The task required them to view three digits and press a button to indicate which one was different, testing their ability to ignore distractions and focus. When the study participants reached young adulthood (between 18 and 21 years old), they completed an assessment measuring their likelihood of engaging in positive social risk taking (the Domain Specific Risk-Taking Scale).
The researchers used statistical modeling to track the adolescents’ brain development over the four years of fMRI scans. The results showed that, generally, frontoparietal activation decreased as the teens got older, reflecting a maturing, more efficient brain network. However, adolescents who experienced more unpredictable life events during this period had higher levels of frontoparietal activation by age 17, suggesting their cognitive control processing was less efficient than their peers.
In turn, this higher brain activation at age 17 was associated with slightly lower positive social risk taking when participants were between 18 and 21 years old.
The study authors tested a statistical mediation model proposing that unpredictability (as reported by parents when participants were 14-17 years old) hinders the development of the brain’s cognitive control centers, leading to increased, inefficient activation in the frontoparietal region at age 17. In turn, this less mature brain functioning leads to a lower willingness to take positive social risks in young adulthood (18-21 years of age). The results showed a significant “indirect effect,” meaning this chain of events is highly plausible.
“The findings have important implications for understanding the antecedents of risk-taking behaviors by highlighting the role of neurocognitive functioning in linking environmental unpredictability to positive social risk outcomes,” the study authors concluded.
The study contributes to the scientific understanding of how childhood experiences physically alter the brain and shape personality characteristics observed in adulthood. However, it should be noted that the observed associations were relatively weak, and simple bivariate correlations did not indicate a direct, straight-line association between unpredictability in adolescence and positive social risk taking in young adulthood (the connection only appeared when factoring in the brain development data).
The paper, “Environmental Unpredictability Predicts Positive Social Risk Taking through Neural Cognitive Control,” was authored by Morgan Lindenmuth, Celina Meyer, Jacob Lee, Laurence Steinberg, Brooks Casas, and Jungmeen Kim-Spoon.
-------------------------------------------------
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NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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It's primitive... but it works... mostly...
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #UnpredictableChildhoods #PositiveSocialRisks #CognitiveControl #Frontoparietal #Neuroscience #BrainDevelopment #AdolescentToAdult #RiskTaking #Neurodevelopment #SocialCognition
-
Harsh Parenting Biologically Distorts Child Stress Regulation
Summary: A new study provides biological proof for how aggressive parenting alters a child’s ability to handle stress.…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Health #braindevelopment #brainresearch #developmentalneuroscience #Mentalhealth #neurobiology #neurodevelopment #Neuroscience #Parenting #PennState #Psychology #stress
https://www.newsbeep.com/us/646290/ -
Harsh Parenting Biologically Distorts Child Stress Regulation
Summary: A new study provides biological proof for how aggressive parenting alters a child’s ability to handle stress.…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Health #braindevelopment #brainresearch #developmentalneuroscience #Mentalhealth #neurobiology #neurodevelopment #Neuroscience #Parenting #PennState #Psychology #stress
https://www.newsbeep.com/us/646290/ -
DATE: May 15, 2026 at 10:00AM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Puberty hormones shape the adolescent female brain before physical changes appear
A recent study has identified how specific puberty hormones relate to the physical structure and functional wiring of the adolescent female brain. The findings suggest that hormones like estradiol and testosterone are linked to distinct brain regions that support memory, emotion, and spatial awareness. This research was published in the journal Human Brain Mapping.
Adolescence is a period of rapid biological and emotional change driven largely by puberty. During this time, the brain undergoes significant development, which scientists suspect is influenced by rising hormone levels. These changes coincide with a higher risk for mental health issues like anxiety and depression, particularly in young females.
Exploring how hormones shape the developing female brain provides evidence that might explain the emergence of these emotional challenges. In the past, studies looking at the relationship between hormones and brain development in adolescents have produced mixed results. Many previous research efforts relied on small groups of participants.
In addition, older studies often focused on only one type of brain imaging at a time. This specific focus can make it difficult to see the full picture of how hormones affect the entire brain. To address these gaps, researchers wanted to look at multiple hormones and multiple brain imaging techniques simultaneously in a very large group of young females.
“Puberty is thought to influence how the adolescent brain develops, shaping social and emotional behavior,” said Muskan Khetan, a doctoral candidate at the University of Melbourne and the lead author of the study. “Most research has focused on visible physical changes, but hormone changes actually begin earlier, before these signs appear, and we know far less about their effects on the brain.”
Khetan noted that this is an important gap, because hormones may serve as some of the earliest biological signals that puberty has begun. “Using a larger sample than is typical in this area of research, we set out to map how these hormonal changes organize the brain in adolescent girls, thereby helping us to better understand how this developmental period shapes social and emotional development,” Khetan said. “We focused on girls because their hormone patterns during puberty are more complex and have been relatively understudied.”
To conduct the study, the authors analyzed data from the Adolescent Brain Cognitive Development Study, which is a massive ongoing project tracking child health in the United States. They focused on a specific sample of 3,024 adolescent females. The participants ranged in age from eight to thirteen years old, with an average age of about ten.
The scientists measured the levels of three specific steroid hormones using saliva samples provided by the participants. These hormones included estradiol, which is a primary female sex hormone, as well as testosterone and dehydroepiandrosterone. While testosterone and dehydroepiandrosterone are often categorized as male hormones, they are present and active in females as well, playing a role in physical growth and brain development.
To understand the brain, the researchers used several different types of magnetic resonance imaging. First, they looked at structural imaging, which measures the physical shape, thickness, and volume of the brain’s gray matter. Gray matter consists of the main bodies of brain cells where information is processed and stored.
They also used diffusion-weighted imaging to look at the brain’s white matter. White matter acts like the brain’s communication highway, consisting of long nerve fibers that connect different regions and allow them to send signals to one another. Analyzing white matter helps researchers understand the strength and organization of these internal pathways.
The team also used functional magnetic resonance imaging to see how the brain operates over time. They measured resting-state connectivity, which shows how different brain networks communicate when a person is just lying still. They also recorded brain activity while the participants completed a specific task that required them to look at pictures of faces and places and remember what they had seen.
With all this data, the researchers applied an advanced mathematical model known as elastic-net regression. This statistical technique allowed them to look at hundreds of brain measurements simultaneously to find which ones best predicted the levels of the three hormones. They trained their model on a portion of the data and tested it on the rest, which helps ensure the results are reliable.
The researchers found that estradiol was most strongly associated with the physical structure of the prefrontal cortex and premotor regions. The prefrontal cortex is located at the front of the brain and helps manage complex behaviors like planning, regulating emotions, and working memory. Higher levels of estradiol were linked to variations in the thickness and folding of these specific areas.
Estradiol also showed a strong relationship with the brain’s resting-state functional connectivity. It was associated with how the visual networks communicated with the thalamus, a deep brain structure that relays sensory information. It was also linked to connections between memory-related brain networks and the caudate, an area involved in learning and action planning.
The two androgens, testosterone and dehydroepiandrosterone, showed a different pattern of associations. These hormones were most strongly connected to the structure of the parietal and occipital lobes, which are located toward the back of the brain. These regions are primarily involved in processing visual information and spatial awareness, helping a person understand where objects are in their environment.
Higher levels of both testosterone and dehydroepiandrosterone were associated with a thinner outer layer of the brain in these visual and spatial areas. While a thinner brain layer might sound negative, it is actually a normal part of brain maturation during adolescence. The brain typically prunes away unused connections to become more efficient as a child grows.
Dehydroepiandrosterone was the only hormone in the study that showed a relationship with how the brain functioned during the active memory and emotion task. Higher levels of this hormone were linked to increased activity in areas of the brain that process faces and emotions. This suggests that this specific hormone might play a role in how young females react to emotional situations.
Even though the hormones had their own unique associations, the researchers also found some overlapping effects. All three hormones were linked to the structure of the insula, a brain region involved in experiencing internal emotions, and the temporoparietal junction, which helps people understand the thoughts and feelings of others. They were also all associated with the white matter fibers connecting the left and right sides of the prefrontal cortex.
“What stood out was the overlapping effects of these hormones on the brain,” Khetan told PsyPost. “The existing literature tends to draw fairly clean lines, estradiol linked to emotional behavior, testosterone and dehydroepiandrosterone to visuospatial processing, but our data showed these hormones also converge on the same brain systems involved in social and emotional processing.”
Khetan explained that this overlap actually reflects well-established biology. “Testosterone and dehydroepiandrosterone can be converted into estradiol in the body, where it then acts on the same receptors,” Khetan said. “Seeing that shared biological mechanism reflected in brain patterns was one of the more interesting aspects of what we found.”
The magnitude of these hormone-brain connections is also an important piece of the puzzle. “The core message is that puberty is a sensitive period, and hormonal changes may be reshaping the brain even before physical development is visible,” Khetan explained. “Our study doesn’t directly measure behavior or clinical outcomes, but it shows that these hormones are actively organizing brain systems central to both emotion and visuospatial processing.”
Khetan pointed out that the statistical effects they found were small, which is a common occurrence in hormone research because hormone levels can vary a lot from person to person. Because of this high variability, large studies are needed to identify reliable biological patterns. “In short, puberty is not just about visible physical changes,” Khetan added. “Important hormonal shifts shape the brain, and thereby behavior.”
As with all research, there are some limitations to consider. “This study identifies associations, it does not establish cause and effect,” Khetan noted. “It’s also worth noting that we examined hormone-brain relationships at a single point in time rather than tracking individuals longitudinally, so we can’t yet speak to how these patterns unfold over the course of development.”
Because age and puberty happen at the same time, it can be difficult to separate changes caused specifically by hormones from changes that just happen naturally as a child gets older. “These findings are best read as an early contribution to understanding how hormones shape the adolescent brain, not as a complete picture,” Khetan said. “Translating these brain-level findings into specific behavioral or clinical outcomes will require further research.”
Another limitation is that the researchers only studied females. Because the scientists did not have estradiol measurements for the males in the broader study, they could not compare the two sexes. Future research will need to include both males and females to see if these hormone-brain relationships apply universally.
Looking ahead, the researchers hope to build on this work by examining how biology and life experiences intersect. “Collecting non-invasive hormonal data from adolescents is genuinely challenging, which is part of why this area remains understudied,” Khetan said. “My broader goal is to understand not just how hormone levels change during puberty, but how those changes interact with environmental factors, such as stress or adversity, and with physical development, to shape the brain and mental health over time.”
Khetan is especially interested in what drives individual differences, specifically why some adolescents show greater vulnerability while others remain resilient. “My own research points to two additional layers of complexity: the timing and pace at which hormones rise matter beyond their absolute levels, and the way hormones fluctuate across a month varies between individuals in ways that appear relevant to adaptability and risk,” Khetan explained. “Ultimately, I hope this line of research can help identify early biological markers that flag who may be most at risk, before problems have a chance to emerge.”
The study, “Pubertal Hormones and the Early Adolescent Female Brain: A Multimodality Brain MRI Study,” was authored by Muskan Khetan, Nandita Vijayakumar, Ye Ella Tian, Megan M Herting, Michele O’Connell, Marc Seal, and Sarah Whittle.
-------------------------------------------------
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Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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It's primitive... but it works... mostly...
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #PubertyBrainDevelopment #AdolescentFemaleBrain #HormonesAndBrain #EstradiolEffects #VisuospatialProcessing #EmotionMemoryConnectivity #TeenMentalHealth #BrainImagingResearch #Neurodevelopment #HormoneBrainLink
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DATE: May 15, 2026 at 10:00AM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Puberty hormones shape the adolescent female brain before physical changes appear
A recent study has identified how specific puberty hormones relate to the physical structure and functional wiring of the adolescent female brain. The findings suggest that hormones like estradiol and testosterone are linked to distinct brain regions that support memory, emotion, and spatial awareness. This research was published in the journal Human Brain Mapping.
Adolescence is a period of rapid biological and emotional change driven largely by puberty. During this time, the brain undergoes significant development, which scientists suspect is influenced by rising hormone levels. These changes coincide with a higher risk for mental health issues like anxiety and depression, particularly in young females.
Exploring how hormones shape the developing female brain provides evidence that might explain the emergence of these emotional challenges. In the past, studies looking at the relationship between hormones and brain development in adolescents have produced mixed results. Many previous research efforts relied on small groups of participants.
In addition, older studies often focused on only one type of brain imaging at a time. This specific focus can make it difficult to see the full picture of how hormones affect the entire brain. To address these gaps, researchers wanted to look at multiple hormones and multiple brain imaging techniques simultaneously in a very large group of young females.
“Puberty is thought to influence how the adolescent brain develops, shaping social and emotional behavior,” said Muskan Khetan, a doctoral candidate at the University of Melbourne and the lead author of the study. “Most research has focused on visible physical changes, but hormone changes actually begin earlier, before these signs appear, and we know far less about their effects on the brain.”
Khetan noted that this is an important gap, because hormones may serve as some of the earliest biological signals that puberty has begun. “Using a larger sample than is typical in this area of research, we set out to map how these hormonal changes organize the brain in adolescent girls, thereby helping us to better understand how this developmental period shapes social and emotional development,” Khetan said. “We focused on girls because their hormone patterns during puberty are more complex and have been relatively understudied.”
To conduct the study, the authors analyzed data from the Adolescent Brain Cognitive Development Study, which is a massive ongoing project tracking child health in the United States. They focused on a specific sample of 3,024 adolescent females. The participants ranged in age from eight to thirteen years old, with an average age of about ten.
The scientists measured the levels of three specific steroid hormones using saliva samples provided by the participants. These hormones included estradiol, which is a primary female sex hormone, as well as testosterone and dehydroepiandrosterone. While testosterone and dehydroepiandrosterone are often categorized as male hormones, they are present and active in females as well, playing a role in physical growth and brain development.
To understand the brain, the researchers used several different types of magnetic resonance imaging. First, they looked at structural imaging, which measures the physical shape, thickness, and volume of the brain’s gray matter. Gray matter consists of the main bodies of brain cells where information is processed and stored.
They also used diffusion-weighted imaging to look at the brain’s white matter. White matter acts like the brain’s communication highway, consisting of long nerve fibers that connect different regions and allow them to send signals to one another. Analyzing white matter helps researchers understand the strength and organization of these internal pathways.
The team also used functional magnetic resonance imaging to see how the brain operates over time. They measured resting-state connectivity, which shows how different brain networks communicate when a person is just lying still. They also recorded brain activity while the participants completed a specific task that required them to look at pictures of faces and places and remember what they had seen.
With all this data, the researchers applied an advanced mathematical model known as elastic-net regression. This statistical technique allowed them to look at hundreds of brain measurements simultaneously to find which ones best predicted the levels of the three hormones. They trained their model on a portion of the data and tested it on the rest, which helps ensure the results are reliable.
The researchers found that estradiol was most strongly associated with the physical structure of the prefrontal cortex and premotor regions. The prefrontal cortex is located at the front of the brain and helps manage complex behaviors like planning, regulating emotions, and working memory. Higher levels of estradiol were linked to variations in the thickness and folding of these specific areas.
Estradiol also showed a strong relationship with the brain’s resting-state functional connectivity. It was associated with how the visual networks communicated with the thalamus, a deep brain structure that relays sensory information. It was also linked to connections between memory-related brain networks and the caudate, an area involved in learning and action planning.
The two androgens, testosterone and dehydroepiandrosterone, showed a different pattern of associations. These hormones were most strongly connected to the structure of the parietal and occipital lobes, which are located toward the back of the brain. These regions are primarily involved in processing visual information and spatial awareness, helping a person understand where objects are in their environment.
Higher levels of both testosterone and dehydroepiandrosterone were associated with a thinner outer layer of the brain in these visual and spatial areas. While a thinner brain layer might sound negative, it is actually a normal part of brain maturation during adolescence. The brain typically prunes away unused connections to become more efficient as a child grows.
Dehydroepiandrosterone was the only hormone in the study that showed a relationship with how the brain functioned during the active memory and emotion task. Higher levels of this hormone were linked to increased activity in areas of the brain that process faces and emotions. This suggests that this specific hormone might play a role in how young females react to emotional situations.
Even though the hormones had their own unique associations, the researchers also found some overlapping effects. All three hormones were linked to the structure of the insula, a brain region involved in experiencing internal emotions, and the temporoparietal junction, which helps people understand the thoughts and feelings of others. They were also all associated with the white matter fibers connecting the left and right sides of the prefrontal cortex.
“What stood out was the overlapping effects of these hormones on the brain,” Khetan told PsyPost. “The existing literature tends to draw fairly clean lines, estradiol linked to emotional behavior, testosterone and dehydroepiandrosterone to visuospatial processing, but our data showed these hormones also converge on the same brain systems involved in social and emotional processing.”
Khetan explained that this overlap actually reflects well-established biology. “Testosterone and dehydroepiandrosterone can be converted into estradiol in the body, where it then acts on the same receptors,” Khetan said. “Seeing that shared biological mechanism reflected in brain patterns was one of the more interesting aspects of what we found.”
The magnitude of these hormone-brain connections is also an important piece of the puzzle. “The core message is that puberty is a sensitive period, and hormonal changes may be reshaping the brain even before physical development is visible,” Khetan explained. “Our study doesn’t directly measure behavior or clinical outcomes, but it shows that these hormones are actively organizing brain systems central to both emotion and visuospatial processing.”
Khetan pointed out that the statistical effects they found were small, which is a common occurrence in hormone research because hormone levels can vary a lot from person to person. Because of this high variability, large studies are needed to identify reliable biological patterns. “In short, puberty is not just about visible physical changes,” Khetan added. “Important hormonal shifts shape the brain, and thereby behavior.”
As with all research, there are some limitations to consider. “This study identifies associations, it does not establish cause and effect,” Khetan noted. “It’s also worth noting that we examined hormone-brain relationships at a single point in time rather than tracking individuals longitudinally, so we can’t yet speak to how these patterns unfold over the course of development.”
Because age and puberty happen at the same time, it can be difficult to separate changes caused specifically by hormones from changes that just happen naturally as a child gets older. “These findings are best read as an early contribution to understanding how hormones shape the adolescent brain, not as a complete picture,” Khetan said. “Translating these brain-level findings into specific behavioral or clinical outcomes will require further research.”
Another limitation is that the researchers only studied females. Because the scientists did not have estradiol measurements for the males in the broader study, they could not compare the two sexes. Future research will need to include both males and females to see if these hormone-brain relationships apply universally.
Looking ahead, the researchers hope to build on this work by examining how biology and life experiences intersect. “Collecting non-invasive hormonal data from adolescents is genuinely challenging, which is part of why this area remains understudied,” Khetan said. “My broader goal is to understand not just how hormone levels change during puberty, but how those changes interact with environmental factors, such as stress or adversity, and with physical development, to shape the brain and mental health over time.”
Khetan is especially interested in what drives individual differences, specifically why some adolescents show greater vulnerability while others remain resilient. “My own research points to two additional layers of complexity: the timing and pace at which hormones rise matter beyond their absolute levels, and the way hormones fluctuate across a month varies between individuals in ways that appear relevant to adaptability and risk,” Khetan explained. “Ultimately, I hope this line of research can help identify early biological markers that flag who may be most at risk, before problems have a chance to emerge.”
The study, “Pubertal Hormones and the Early Adolescent Female Brain: A Multimodality Brain MRI Study,” was authored by Muskan Khetan, Nandita Vijayakumar, Ye Ella Tian, Megan M Herting, Michele O’Connell, Marc Seal, and Sarah Whittle.
-------------------------------------------------
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It's primitive... but it works... mostly...
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #PubertyBrainDevelopment #AdolescentFemaleBrain #HormonesAndBrain #EstradiolEffects #VisuospatialProcessing #EmotionMemoryConnectivity #TeenMentalHealth #BrainImagingResearch #Neurodevelopment #HormoneBrainLink
-
DATE: May 15, 2026 at 10:00AM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Puberty hormones shape the adolescent female brain before physical changes appear
A recent study has identified how specific puberty hormones relate to the physical structure and functional wiring of the adolescent female brain. The findings suggest that hormones like estradiol and testosterone are linked to distinct brain regions that support memory, emotion, and spatial awareness. This research was published in the journal Human Brain Mapping.
Adolescence is a period of rapid biological and emotional change driven largely by puberty. During this time, the brain undergoes significant development, which scientists suspect is influenced by rising hormone levels. These changes coincide with a higher risk for mental health issues like anxiety and depression, particularly in young females.
Exploring how hormones shape the developing female brain provides evidence that might explain the emergence of these emotional challenges. In the past, studies looking at the relationship between hormones and brain development in adolescents have produced mixed results. Many previous research efforts relied on small groups of participants.
In addition, older studies often focused on only one type of brain imaging at a time. This specific focus can make it difficult to see the full picture of how hormones affect the entire brain. To address these gaps, researchers wanted to look at multiple hormones and multiple brain imaging techniques simultaneously in a very large group of young females.
“Puberty is thought to influence how the adolescent brain develops, shaping social and emotional behavior,” said Muskan Khetan, a doctoral candidate at the University of Melbourne and the lead author of the study. “Most research has focused on visible physical changes, but hormone changes actually begin earlier, before these signs appear, and we know far less about their effects on the brain.”
Khetan noted that this is an important gap, because hormones may serve as some of the earliest biological signals that puberty has begun. “Using a larger sample than is typical in this area of research, we set out to map how these hormonal changes organize the brain in adolescent girls, thereby helping us to better understand how this developmental period shapes social and emotional development,” Khetan said. “We focused on girls because their hormone patterns during puberty are more complex and have been relatively understudied.”
To conduct the study, the authors analyzed data from the Adolescent Brain Cognitive Development Study, which is a massive ongoing project tracking child health in the United States. They focused on a specific sample of 3,024 adolescent females. The participants ranged in age from eight to thirteen years old, with an average age of about ten.
The scientists measured the levels of three specific steroid hormones using saliva samples provided by the participants. These hormones included estradiol, which is a primary female sex hormone, as well as testosterone and dehydroepiandrosterone. While testosterone and dehydroepiandrosterone are often categorized as male hormones, they are present and active in females as well, playing a role in physical growth and brain development.
To understand the brain, the researchers used several different types of magnetic resonance imaging. First, they looked at structural imaging, which measures the physical shape, thickness, and volume of the brain’s gray matter. Gray matter consists of the main bodies of brain cells where information is processed and stored.
They also used diffusion-weighted imaging to look at the brain’s white matter. White matter acts like the brain’s communication highway, consisting of long nerve fibers that connect different regions and allow them to send signals to one another. Analyzing white matter helps researchers understand the strength and organization of these internal pathways.
The team also used functional magnetic resonance imaging to see how the brain operates over time. They measured resting-state connectivity, which shows how different brain networks communicate when a person is just lying still. They also recorded brain activity while the participants completed a specific task that required them to look at pictures of faces and places and remember what they had seen.
With all this data, the researchers applied an advanced mathematical model known as elastic-net regression. This statistical technique allowed them to look at hundreds of brain measurements simultaneously to find which ones best predicted the levels of the three hormones. They trained their model on a portion of the data and tested it on the rest, which helps ensure the results are reliable.
The researchers found that estradiol was most strongly associated with the physical structure of the prefrontal cortex and premotor regions. The prefrontal cortex is located at the front of the brain and helps manage complex behaviors like planning, regulating emotions, and working memory. Higher levels of estradiol were linked to variations in the thickness and folding of these specific areas.
Estradiol also showed a strong relationship with the brain’s resting-state functional connectivity. It was associated with how the visual networks communicated with the thalamus, a deep brain structure that relays sensory information. It was also linked to connections between memory-related brain networks and the caudate, an area involved in learning and action planning.
The two androgens, testosterone and dehydroepiandrosterone, showed a different pattern of associations. These hormones were most strongly connected to the structure of the parietal and occipital lobes, which are located toward the back of the brain. These regions are primarily involved in processing visual information and spatial awareness, helping a person understand where objects are in their environment.
Higher levels of both testosterone and dehydroepiandrosterone were associated with a thinner outer layer of the brain in these visual and spatial areas. While a thinner brain layer might sound negative, it is actually a normal part of brain maturation during adolescence. The brain typically prunes away unused connections to become more efficient as a child grows.
Dehydroepiandrosterone was the only hormone in the study that showed a relationship with how the brain functioned during the active memory and emotion task. Higher levels of this hormone were linked to increased activity in areas of the brain that process faces and emotions. This suggests that this specific hormone might play a role in how young females react to emotional situations.
Even though the hormones had their own unique associations, the researchers also found some overlapping effects. All three hormones were linked to the structure of the insula, a brain region involved in experiencing internal emotions, and the temporoparietal junction, which helps people understand the thoughts and feelings of others. They were also all associated with the white matter fibers connecting the left and right sides of the prefrontal cortex.
“What stood out was the overlapping effects of these hormones on the brain,” Khetan told PsyPost. “The existing literature tends to draw fairly clean lines, estradiol linked to emotional behavior, testosterone and dehydroepiandrosterone to visuospatial processing, but our data showed these hormones also converge on the same brain systems involved in social and emotional processing.”
Khetan explained that this overlap actually reflects well-established biology. “Testosterone and dehydroepiandrosterone can be converted into estradiol in the body, where it then acts on the same receptors,” Khetan said. “Seeing that shared biological mechanism reflected in brain patterns was one of the more interesting aspects of what we found.”
The magnitude of these hormone-brain connections is also an important piece of the puzzle. “The core message is that puberty is a sensitive period, and hormonal changes may be reshaping the brain even before physical development is visible,” Khetan explained. “Our study doesn’t directly measure behavior or clinical outcomes, but it shows that these hormones are actively organizing brain systems central to both emotion and visuospatial processing.”
Khetan pointed out that the statistical effects they found were small, which is a common occurrence in hormone research because hormone levels can vary a lot from person to person. Because of this high variability, large studies are needed to identify reliable biological patterns. “In short, puberty is not just about visible physical changes,” Khetan added. “Important hormonal shifts shape the brain, and thereby behavior.”
As with all research, there are some limitations to consider. “This study identifies associations, it does not establish cause and effect,” Khetan noted. “It’s also worth noting that we examined hormone-brain relationships at a single point in time rather than tracking individuals longitudinally, so we can’t yet speak to how these patterns unfold over the course of development.”
Because age and puberty happen at the same time, it can be difficult to separate changes caused specifically by hormones from changes that just happen naturally as a child gets older. “These findings are best read as an early contribution to understanding how hormones shape the adolescent brain, not as a complete picture,” Khetan said. “Translating these brain-level findings into specific behavioral or clinical outcomes will require further research.”
Another limitation is that the researchers only studied females. Because the scientists did not have estradiol measurements for the males in the broader study, they could not compare the two sexes. Future research will need to include both males and females to see if these hormone-brain relationships apply universally.
Looking ahead, the researchers hope to build on this work by examining how biology and life experiences intersect. “Collecting non-invasive hormonal data from adolescents is genuinely challenging, which is part of why this area remains understudied,” Khetan said. “My broader goal is to understand not just how hormone levels change during puberty, but how those changes interact with environmental factors, such as stress or adversity, and with physical development, to shape the brain and mental health over time.”
Khetan is especially interested in what drives individual differences, specifically why some adolescents show greater vulnerability while others remain resilient. “My own research points to two additional layers of complexity: the timing and pace at which hormones rise matter beyond their absolute levels, and the way hormones fluctuate across a month varies between individuals in ways that appear relevant to adaptability and risk,” Khetan explained. “Ultimately, I hope this line of research can help identify early biological markers that flag who may be most at risk, before problems have a chance to emerge.”
The study, “Pubertal Hormones and the Early Adolescent Female Brain: A Multimodality Brain MRI Study,” was authored by Muskan Khetan, Nandita Vijayakumar, Ye Ella Tian, Megan M Herting, Michele O’Connell, Marc Seal, and Sarah Whittle.
-------------------------------------------------
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NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can read it or subscribe at @PsychResearchBot
Since 1991 The National Psychologist has focused on keeping practicing psychologists current with news, information and items of interest. Check them out for more free articles, resources, and subscription information: https://www.nationalpsychologist.com
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It's primitive... but it works... mostly...
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #PubertyBrainDevelopment #AdolescentFemaleBrain #HormonesAndBrain #EstradiolEffects #VisuospatialProcessing #EmotionMemoryConnectivity #TeenMentalHealth #BrainImagingResearch #Neurodevelopment #HormoneBrainLink
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https://www.europesays.com/uk/924936/ Language and Empathy Have Distinct Origins in the Developing Brain #BrainConnectivity #BrainDevelopment #cognition #CognitiveEvolution #DevelopmentalNeuroscience #fMRI #Health #LanguageDevelopment #neurodevelopment #Neuroscience #OhioStateUniversity #SuperiorTemporalLobe #TheoryOfMind #UK #UnitedKingdom
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https://www.europesays.com/ie/454225/ Astrocytes Identified as Key Target for Treating Fragile X Syndrome #astrocytes #BMPSignaling #BrainResearch #Éire #FragileXSyndrome #Health #IE #Ireland #neurodevelopment #neurology #Neuroscience #SalkInstitute
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PsyPost: More time spent on social media is linked to a thinner cerebral cortex in young adolescents. “New research published in the journal NeuroImage suggests that spending more time on social media is associated with physical differences in the developing brains of young adolescents. Specifically, children who spent more hours on digital platforms exhibited a thinner outer layer of the brain […]
https://rbfirehose.com/2026/04/22/psypost-more-time-spent-on-social-media-is-linked-to-a-thinner-cerebral-cortex-in-young-adolescents/ -
New Rare Genetic Neurodevelopmental Disorder Identified
Summary: Researchers have identified a previously unknown rare genetic disease named RPN1-CDG. The study used whole exome sequencing…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Health #braindevelopment #CDG #Genetics #glycosylation #neurodevelopment #Neurodevelopmentaldisorders #Neuroscience #OSTComplex #RibophorinI #RPN1-CDG #SanfordBurnhamPrebys #Wholeexomesequencing
https://www.newsbeep.com/us/585471/ -
New Rare Genetic Neurodevelopmental Disorder Identified
Summary: Researchers have identified a previously unknown rare genetic disease named RPN1-CDG. The study used whole exome sequencing…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Health #braindevelopment #CDG #Genetics #glycosylation #neurodevelopment #Neurodevelopmentaldisorders #Neuroscience #OSTComplex #RibophorinI #RPN1-CDG #SanfordBurnhamPrebys #Wholeexomesequencing
https://www.newsbeep.com/us/585471/ -
ADHD is more than distraction or hyperactivity — it’s a brain-based condition that affects focus, organization, and impulse control. With the right support, people with ADHD can thrive. 💡
#ADHD #MentalHealth #Neurodevelopment #Telehealth #ADHDAwareness -
ADHD isn’t a lack of willpower — it’s a brain-based condition rooted in neurobiology. With the right diagnosis and treatment, focus and function can improve. 💡
#ADHD #Neurodevelopment #MentalHealth #Telehealth #ADHDAwareness -
🥦 +++ NICHT NUR FÜR EXPERTEN ODER EXPERTINNEN +++ ⚠️
[... #tobacco and #alcohol have large effects on genome wide DNA #methylation while
#marijuana consumption has 🙏 nonsignificant effects.
... related to #neurodevelopment, suggesting the mediation between recreational drug consumption and neurological disorders. ...] #FASD #Alkohol #Söder #Merz #CSU #CDU #SPD #Volksgesundheit #weedmob #Cannabis #science #epigenetik #Medizin #Wissenshaft #Gesundheit #health #janov
-
🥦 +++ NICHT NUR FÜR EXPERTEN ODER EXPERTINNEN +++ ⚠️
[... #tobacco and #alcohol have large effects on genome wide DNA #methylation while
#marijuana consumption has 🙏 nonsignificant effects.
... related to #neurodevelopment, suggesting the mediation between recreational drug consumption and neurological disorders. ...] #FASD #Alkohol #Söder #Merz #CSU #CDU #SPD #Volksgesundheit #weedmob #Cannabis #science #epigenetik #Medizin #Wissenshaft #Gesundheit #health #janov
-
🥦 +++ NICHT NUR FÜR EXPERTEN ODER EXPERTINNEN +++ ⚠️
[... #tobacco and #alcohol have large effects on genome wide DNA #methylation while
#marijuana consumption has 🙏 nonsignificant effects.
... related to #neurodevelopment, suggesting the mediation between recreational drug consumption and neurological disorders. ...] #FASD #Alkohol #Söder #Merz #CSU #CDU #SPD #Volksgesundheit #weedmob #Cannabis #science #epigenetik #Medizin #Wissenshaft #Gesundheit #health #janov
-
🥦 +++ NICHT NUR FÜR EXPERTEN ODER EXPERTINNEN +++ ⚠️
[... #tobacco and #alcohol have large effects on genome wide DNA #methylation while
#marijuana consumption has 🙏 nonsignificant effects.
... related to #neurodevelopment, suggesting the mediation between recreational drug consumption and neurological disorders. ...] #FASD #Alkohol #Söder #Merz #CSU #CDU #SPD #Volksgesundheit #weedmob #Cannabis #science #epigenetik #Medizin #Wissenshaft #Gesundheit #health #janov
-
🥦 +++ NICHT NUR FÜR EXPERTEN ODER EXPERTINNEN +++ ⚠️
[... #tobacco and #alcohol have large effects on genome wide DNA #methylation while
#marijuana consumption has 🙏 nonsignificant effects.
... related to #neurodevelopment, suggesting the mediation between recreational drug consumption and neurological disorders. ...] #FASD #Alkohol #Söder #Merz #CSU #CDU #SPD #Volksgesundheit #weedmob #Cannabis #science #epigenetik #Medizin #Wissenshaft #Gesundheit #health #janov
-
+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #hanf #hemp #marijuana #Gesundheit #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Cannabis
-
⚠️ >>> Forscher ziehen Fazit <<<⚠️
... die 🌱 #Bevölkerung mit #falschenInformationen versorgt ❓ 📡 ➡️ mehr erfahren: ➡️ ➡️ ➡️ https://www.konturen.de/fachbeitraege/cannabislegalisierung-in-kanada-seit-2018/ ☣️
#CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #WEEDMoB #Cannabisgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #Cannabis #Kreislaufwirtschaft
-
+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #cop30 #Cannabis #Kreislaufwirtschaft
-
n-tv Sendung "Frühstart"
+++ "Es war furchtbar" +++ 😬
Friedrich #Merz spricht im Interview über persönliche 🌱 #Cannabis-Erfahrung
21. März 2024 16:58 Uhr
https://www.stern.de/politik/deutschland/cannabis-legalisierung--friedrich-merz-fand-eigene-erfahrung--furchtbar--34564956.html#CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #WEEDMoB #Cannabisgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #Kreislaufwirtschaft #klima
-
⚠️ >>> Forscher ziehen Fazit <<<⚠️
... die 🌱 #Bevölkerung mit #falschenInformationen versorgt ❓ 📡 ➡️ mehr erfahren: ➡️ ➡️ ➡️ https://www.konturen.de/fachbeitraege/cannabislegalisierung-in-kanada-seit-2018/ ☣️
#CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #WEEDMoB #Cannabisgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #Cannabis #Kreislaufwirtschaft
-
Menzel fordert stattdessen eine „medizinisch verantwortungsvolle #Telemedizin“, also Onlineplattformen, auf denen Ärztinnen und Ärzte per Video 🌱 #Cannabis verschreiben können.
https://taz.de/Verkauf-von-medizinischem-Cannabis/!6134152/
#CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #Reiche #WEEDMoB #Hanfgeschichten #hanf #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #Cannabis #Kreislaufwirtschaft
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⚠️ >>> Forscher ziehen Fazit <<<⚠️
... die 🌱 #Bevölkerung mit #falschenInformationen versorgt ❓ 📡 ➡️ mehr erfahren: ➡️ ➡️ ➡️ https://www.konturen.de/fachbeitraege/cannabislegalisierung-in-kanada-seit-2018/ ☣️
#CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #Cannabis #Kreislaufwirtschaft
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n-tv Sendung "Frühstart"
+++ "Es war furchtbar" +++ 😬
Friedrich #Merz spricht im Interview über persönliche 🌱 #Cannabis-Erfahrung
21. März 2024 16:58 Uhr
https://www.stern.de/politik/deutschland/cannabis-legalisierung--friedrich-merz-fand-eigene-erfahrung--furchtbar--34564956.html#CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #Cannabis #Kreislaufwirtschaft
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+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #cop30 #Cannabis #Kreislaufwirtschaft
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https://www.arte.tv/de/videos/118269-000-A/europas-drogenmafia-1-2/
#Dokumentation, Regie: #SofiaCoppola (F/M 2025, 53 Min)
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cannabis #Grundrechte #drogen #mafia #doku
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Harte Wahrheiten zutiefst verdrängt➡️ ➡️ ➡️ https://youtu.be/SDHzONLYI_4 🌐 📡
#Dokumentation, Regie: #SofiaCoppola (F/M 2025, 53 Min)#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cannabis #Grundrechte #drogen #mafia #doku
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+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #cop30 #Cannabis #Kreislaufwirtschaft
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+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #cop30 #Cannabis #Kreislaufwirtschaft
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+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #cop30 #Cannabis #Kreislaufwirtschaft
-
+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #cop30 #Cannabis #Kreislaufwirtschaft
-
+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #cop30 #Cannabis #Kreislaufwirtschaft
-
+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #cop30 #Cannabis #Kreislaufwirtschaft
-
+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #cop30 #Cannabis #Kreislaufwirtschaft
-
+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #cop30 #Cannabis #Kreislaufwirtschaft
-
+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++
lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]
#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana #Gesundheit #CanG #SPD #CSU #CDU #DIELINKE #FDP #GRÜNE #Cancer #Krebs #Grundrechte #Deutschland #Schweiz #Medcan #cop30 #Cannabis #Kreislaufwirtschaft