#methylation — Public Fediverse posts

#MTHFR #Genetics #Methylation #HealthTips #BrainHealth #LongevityDiet #LongevityLifestyle #NutritionalScience #Folate #Supplements #biohack #biohacking #biohacker #biohackingsecrets #biohackers #biohacks #WellnessJourney https://mastodon.social/@biohackingpathway/117191936678452612

Smog in the Clock Genes: DNA Methylation Links Air Pollution to Poor Sleep

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https://1ban.news/pm25-circadian-methylation-sleep-gehas/

#1ban #pm25 #circadian #methylation #sleep #neuroscience

#Hypothyroidism #BirthControl #NutrientDepletion #ThyroidHealth #WomensHealth #Vitamins #Minerals #Methylation #Hormones #Wellness #Hypothyroidism #BirthControl #NutrientDepletion #ThyroidHealth #WomensHealth #Vitamins #Minerals #Methylation #Hormones #Wellness https://mastodon.social/@biohackingpathway/116937148929445061

https://mastodon.social/@Karl_Theodor/116510024121418074

#Cannabis #antistress #antitrauma #pain #stress #epignetics #trauma #methylation #methylierung #Hanfwissen #bundesregierung

RE: https://mastodon.social/@sflorg/116488510685437541

🌱 👯 Komplexe Zusammenhänge 🧩 entpuzzelt 😀

#Wissenschaft #Zusammenhänge #Cannabis #Cannabinoide #Schmerzforschung #Traumatisierung #Endocannabinoidsystem #science #trauma #antitrauma #cellprotection #Epigenetik #epigenetics #Schmerz #Missbrauch #Ausgrenzung #Verfolgung #Vernichtung #Krieg #warondrugs #Weedmob #Hanfwissen #Hanfgeschichten #SPD #CSU #CDU #DIELINKE #Grüne #Menschenrechte #Grundrechte #Gesundheit #methylation #methylierung #Streeck #NinaWarken #Medizin #DNA #Hanf #hemp #marijuana

Age and early life adversity shape epigenome heterogeneity across tissues in macaques | Science

Different tissues and organs age at different rates, each individually.
Researchers measured DNA methylation profiles—chemical markers that change with age and reflect environmental influences—in 14 different macaque tissues. Analysis of age-related changes revealed striking heterogeneity: although methylation shifted toward certain average values ​​in each tissue over the years, the direction and magnitude of these shifts varied greatly between organs. Only a small number of epigenetic markers aged synchronously across the body, while most changes were tissue-specific. This means that standard blood tests, often used as "aging clocks," reflect only a fraction of the overall picture. Within a single individual, age-related changes in different tissues were more coordinated than between individuals, but this coordination decreased with age—tissues began to age "out of sync," with this heterogeneity evident from early life.
A study of the effects of early adversity (primarily maternal loss) revealed an unexpected contrast. Unlike age-related changes, which were tissue-specific, the effects of early stress manifested as a coordinated response throughout the entire organism: the same DNA regions exhibited similar methylation changes in most tissues, with the most pronounced changes occurring in immune and endocrine organs and tissues with long-lived cells. Moreover, different forms of stress (for example, maternal loss or drought) primarily affected different sets of genetic loci, suggesting the existence of multiple molecular pathways through which adversity leaves its mark on the genome.
Thus, the study demonstrates a fundamental difference: aging is a disintegrative, tissue-specific process, whereas early life trauma leaves a coordinated, systemic imprint that, although overlapping with age-related targets, acts through different mechanisms, shaping the organism's aging trajectory in its own way.

#science #biology #methylation #aging #news #genetics

https://www.science.org/doi/10.1126/science.aea4922

#COMTGene #MentalHealth #GeneMutation #Methylation #GeneticTesting #BrainHealth #StressManagement #Prioritization #wellbeingatwork #wellbeingtips #wellnessurlaub #Neurocience #MentalWellbeing https://mastodon.social/@biohackingpathway/116736123713280362

https://www.europesays.com/fr/988437/ Dépression post-partum : ce nouveau test pourrait repérer les femmes à risque pendant la grossesse #Accouchement #Biologie #Biomarqueurs #cerveau #Dépression #FR #France #gênés #Grossesse #Health #IdéeSuicidaire #LesTendances #Méthylation #Naissance #Psychologie #Santé #TestSanguin #TroublesDuSommeil

https://www.europesays.com/ch-fr/167839/ Dépression post-partum : ce nouveau test pourrait repérer les femmes à risque pendant la grossesse #accouchement #Biologie #biomarqueurs #cerveau #Dépression #gènes #Grossesse #Health #IdéeSuicidaire #LesTendances #méthylation #naissance #Psychologie #Santé #Suisse #TestSanguin #TroublesDuSommeil

https://www.europesays.com/be-fr/134721/ Dépression post-partum : ce nouveau test pourrait repérer les femmes à risque pendant la grossesse #accouchement #BE #BEFr #Belgique #Belgium #Biologie #biomarqueurs #Cerveau #Dépression #Gènes #Grossesse #Health #IdéeSuicidaire #LesTendances #méthylation #naissance #psychologie #Santé #TestSanguin #TroublesDuSommeil

RE: https://mastodon.social/@sflorg/116488510685437541

🌱 👯 Komplexe Zusammenhänge 🧩 entpuzzelt 😀

#Wissenschaft #Zusammenhänge #Cannabis #Cannabinoide #Schmerzforschung #Traumatisierung #Endocannabinoidsystem #science #trauma #antitrauma #cellprotection #Epigenetik #epigenetics #Schmerz #Missbrauch #Ausgrenzung #Verfolgung #Vernichtung #Krieg #warondrugs #Weedmob #Hanfwissen #Hanfgeschichten #SPD #CSU #CDU #DIELINKE #Grüne #Menschenrechte #Grundrechte #Gesundheit #methylation #methylierung #Streeck #NinaWarken #Medizin #DNA #Hanf #hemp #marijuana

🌱 👯 Komplexe Zusammenhänge 🧩 entpuzzelt 😀

#Wissenschaft #Zusammenhänge #Cannabis #Cannabinoide #Schmerzforschung #Traumatisierung #Endocannabinoidsystem #science #trauma #antitrauma #cellprotection #Epigenetik #epigenetics #Schmerz #Missbrauch #Ausgrenzung #Verfolgung #Vernichtung #Krieg #warondrugs #Weedmob #Hanfwissen #Hanfgeschichten #SPD #CSU #CDU #DIELINKE #Grüne #Menschenrechte #Grundrechte #Gesundheit #methylation #methylierung #Streeck #NinaWarken #Medizin #DNA #Hanf #hemp #marijuana

RE: https://mastodon.social/@sflorg/116488510685437541

🌱 👯 Komplexe Zusammenhänge 🧩 entpuzzelt 😀

#Wissenschaft #Zusammenhänge #Cannabis #Cannabinoide #Schmerzforschung #Traumatisierung #Endocannabinoidsystem #science #trauma #antitrauma #cellprotection #Epigenetik #epigenetics #Schmerz #Missbrauch #Ausgrenzung #Verfolgung #Vernichtung #Krieg #warondrugs #Weedmob #Hanfwissen #Hanfgeschichten #SPD #CSU #CDU #DIELINKE #Grüne #Menschenrechte #Grundrechte #Gesundheit #methylation #methylierung #Streeck #NinaWarken #Medizin #DNA #Hanf #hemp #marijuana

🌱 👯 Komplexe Zusammenhänge 🧩 entpuzzelt 😀

https://mastodon.social/@sflorg/116488510685437541

#Wissenschaft #Zusammenhänge #Cannabis #Cannabinoide #Schmerzforschung #Traumatisierung #Endocannabinoidsystem #science #trauma #antitrauma #cellprotection #Epigenetik #epigenetics #Schmerz #Missbrauch #Ausgrenzung #Verfolgung #Vernichtung #Krieg #warondrugs #Weedmob #Hanfwissen #Hanfgeschichten #SPD #CSU #CDU #DIELINKE #Grüne #Menschenrechte #Grundrechte #Gesundheit #methylation #methylierung #Streeck #NinaWarken #Medizin #DNA

🌱 👯 Komplexe Zusammenhänge 🧩 entpuzzelt 😀

https://mastodon.social/@sflorg/116488510685437541

#Wissenschaft #Zusammenhänge #Cannabis #Cannabinoide #Schmerzforschung #Traumatisierung #Endocannabinoidsystem #science #trauma #antitrauma #cellprotection #Epigenetik #epigenetics #Schmerz #Missbrauch #Ausgrenzung #Verfolgung #Vernichtung #Krieg #warondrugs #Weedmob #Hanfwissen #Hanfgeschichten #SPD #CSU #CDU #DIELINKE #Grüne #Menschenrechte #Grundrechte #Gesundheit #methylation #methylierung

🌱 👯 Komplexe Zusammenhänge 🧩 entpuzzelt 😀

#Wissenschaft #Zusammenhänge #Cannabis #Cannabinoide #Schmerzforschung #Traumatisierung #Endocannabinoidsystem #science #trauma #antitrauma #cellprotection #antioxydant #antiinflammatory #Epigenetik #epigenetics #Schmerz #Missbrauch #Ausgrenzung #Verfolgung #Vernichtung #Krieg #warondrugs #Weedmob #Hanfwissen #Hanfgeschichten #SPD #CSU #CDU #DIELINKE #Grüne #Menschenrechte #Grundrechte #Gesundheit #methylation #methylierung

https://mastodon.social/@sflorg/116488510685437541

https://mastodon.social/@Karl_Theodor/116510024121418074

#Cannabis #antistress #antitrauma #pain #stress #epignetics #trauma #methylation #methylierung #Hanfwissen #bundesregierung

https://www.europesays.com/be-fr/92207/ Et si le cerveau vieillissait à cause d’un dérèglement caché dans nos gènes ? #BE #BEFr #Belgique #Belgium #Cerveau #DysfonctionnementNeuronal #Épigénétique #GènesSauteurs #genome #Health #LesTendances #méthylation #Microglie #Santé #vieillissement #VieillissementCérébral

https://www.europesays.com/ch-fr/?p=111912 Et si le cerveau vieillissait à cause d’un dérèglement caché dans nos gènes ? #cerveau #DysfonctionnementNeuronal #épigénétique #GènesSauteurs #Génome #Health #LesTendances #méthylation #Microglie #Santé #Suisse #vieillissement #VieillissementCérébral

#MTHFR #Genetics #Methylation #HealthTips #BrainHealth #LongevityDiet #LongevityLifestyle #NutritionalScience #Folate #Supplements #biohack #biohacking #biohacker #biohackingsecrets #biohackers #biohacks #WellnessJourney https://mastodon.social/@biohackingpathway/116489820175834563

https://www.europesays.com/ch-fr/97831/ Les « empreintes digitales » de méthylation de l’ADN identifient les sites primaires des cancers métastatiques #cancers #des #digitales #empreintes #Health #identifient #l'ADN #les #métastatiques #méthylation #primaires #Santé #sites #Suisse

https://www.europesays.com/ch-fr/96289/ Une nouvelle étude révèle l’enzyme CRISPR qui répond à la méthylation de l’ADN humain #CRISPR #étude #Health #humain #l39ADN #l39enzyme #méthylation #nouvelle #qui #répond #révèle #Santé #Suisse #Une

https://www.europesays.com/be-fr/80161/ Une nouvelle étude révèle l’enzyme CRISPR qui répond à la méthylation de l’ADN humain #BE #BEFr #Belgique #Belgium #CRISPR #étude #Health #humain #l39ADN #l39enzyme #méthylation #nouvelle #qui? #répond #révèle #Santé #Une

https://www.europesays.com/ie/441059/ Methylation-sensitive Cas9 can selectively target DNA in tumor cells #Biochemistry #cancer #Cas9 #Éire #GeneEditing #IE #Ireland #Methylation #oncology #Science

New publication: #Epigenomic response to #insect #herbivory in Lombardy #poplar: assessing geographic variation in #DNA #methylation changes.
https://doi.org/10.1007/s11295-025-01727-4

#Hypothyroidism #BirthControl #NutrientDepletion #ThyroidHealth #WomensHealth #Vitamins #Minerals #Methylation #Hormones #Wellness #Hypothyroidism #BirthControl #NutrientDepletion #ThyroidHealth #WomensHealth #Vitamins #Minerals #Methylation #Hormones #Wellness https://mastodon.social/@biohackingpathway/116234810716707984

https://www.europesays.com/uk/822522/ New Research Links Daily Multivitamins to Slower Biological Aging #Aging #cocoa #COSMOSTrial #diet #DNA #DNAMethylation #EpigeneticAging #EpigeneticClock #Epigenetics #Gene #Genome #Health #Methylation #Multimineral #multivitamin #Nutrition #UK #UnitedKingdom #vitamin

New Research Links Daily Multivitamins to Slower Biological Aging

In a randomized clinical trial of older adults, researchers found that taking multivitamins for two years modestly slowed…
#NewsBeep #News #Nutrition #aging #cocoa #COSMOStrial #Diet #dna #DNAmethylation #Epigeneticaging #Epigeneticclock #epigenetics #Gene #Genome #Health #Methylation #Multimineral #multivitamin #UK #UnitedKingdom #Vitamin
https://www.newsbeep.com/uk/471971/

New Research Links Daily Multivitamins to Slower Biological Aging

In a randomized clinical trial of older adults, researchers found that taking multivitamins for two years modestly slowed…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Nutrition #aging #Cocoa #COSMOStrial #Diet #DNA #DNAmethylation #Epigeneticaging #Epigeneticclock #epigenetics #Gene #Genome #Health #methylation #Multimineral #multivitamin #vitamin
https://www.newsbeep.com/us/519642/

New Research Links Daily Multivitamins to Slower Biological Aging

In a randomized clinical trial of older adults, researchers found that taking multivitamins for two years modestly slowed…
#NewsBeep #News #Nutrition #aging #CA #Canada #cocoa #COSMOStrial #Diet #DNA #DNAmethylation #Epigeneticaging #Epigeneticclock #epigenetics #Gene #Genome #Health #Methylation #Multimineral #multivitamin #vitamin
https://www.newsbeep.com/ca/531930/

https://www.europesays.com/ie/380101/ New Research Links Daily Multivitamins to Slower Biological Aging #Aging #cocoa #COSMOSTrial #diet #DNA #DNAMethylation #Éire #EpigeneticAging #EpigeneticClock #Epigenetics #Gene #Genome #Health #IE #Ireland #Methylation #Multimineral #multivitamin #Vitamin

#COMTGene #MentalHealth #GeneMutation #Methylation #GeneticTesting #BrainHealth #StressManagement #Prioritization #wellbeingatwork #wellbeingtips #wellnessurlaub #Neurocience #MentalWellbeing https://mastodon.social/@biohackingpathway/116033774224527985

🥦 +++ NICHT NUR FÜR EXPERTEN ODER EXPERTINNEN +++ ⚠️

[... #tobacco and #alcohol have large effects on genome wide DNA #methylation while

#marijuana consumption has 🙏 nonsignificant effects.

... related to #neurodevelopment, suggesting the mediation between recreational drug consumption and neurological disorders. ...] #FASD #Alkohol #Söder #Merz #CSU #CDU #SPD #Volksgesundheit #weedmob #Cannabis #science #epigenetik #Medizin #Wissenshaft #Gesundheit #health #janov

https://mastodon.social/@Karl_Theodor/115011469148230159

#MTHFR #Genetics #Methylation #HealthTips #BrainHealth #LongevityDiet #LongevityLifestyle #NutritionalScience #Folate #Supplements #biohack #biohacking #biohacker #biohackingsecrets #biohackers #biohacks #WellnessJourney https://mastodon.social/@biohackingpathway/115783220399413170

#Hypothyroidism #BirthControl #NutrientDepletion #ThyroidHealth #WomensHealth #Vitamins #Minerals #Methylation #Hormones #Wellness #Hypothyroidism #BirthControl #NutrientDepletion #ThyroidHealth #WomensHealth #Vitamins #Minerals #Methylation #Hormones #Wellness https://mastodon.social/@biohackingpathway/115526981847628213

#Cannabis #Trauma #Vererbung von permanenter #Angst durch die prohibitionistische andauernde #Diskriminierung & #Menschenjagd?

#Systembiologie #Epigenetik #methylation #Methylierung #Janov

#Endocrinology & #Metabolism

Sperm microRNAs may enable transmission of exercise benefits from fathers to children
by #NanjingUniversity

edited by Gaby Clark, reviewed by Robert Egan

#WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana

#Streeck 🙏 #NinaWarken 🙏 #Gesundheit
#Merz #Söder #Klingbeil #Reiche 😀

Vera 😍 🩷
Jahrgang: 1983
Diagnose: #MultipleSklerose

«Ich will in die Welt schreien, wie unglaublich wirksam Cannabis ist.» - Vera

weiterlesen: ➡️ 👯 https://www.medcan.ch/ueber-uns/unsere-geschichten/vera

«#Cannabis hat mir die Freude am Leben zurückgegeben.» 😃 #MEDCAN #Schweiz

#WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana

#Streeck 🙏 #NinaWarken 🙏
#Merz #Söder #Klingbeil #Reiche 😀

#Gesundheit
#Immunsystem
#Endocannabinoidsystem
#Epigenetik
#epigenetics
#trauma
#methylation
#endocrinedisruptors
#MaxPlanckInstitut

@spiegel.de #wissen #knowledge #panorama

Um #Alzheimer zu heilen, müssen wir die Ursachen der Krankheit entschlüsseln – ein langwieriger Prozess. Helfen Sie uns darum mit einer Fördermitgliedschaft. 🙏 https://www.alzheimer-forschung.de/forschung/forschungsprojekte/projektdatenbank/projekt/cannabinoids-as-neuroprotectants-and-modulators-of-the-processing-of-amyloid-precursor-protein-app/

#WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana

#Streeck 🙏 #NinaWarken 🙏
#Merz #Söder #Klingbeil #Reiche 😀

#Cannabis #Gesundheit #Immunsystem #Endocannabinoidsystem #Epigenetik #epigenetics #trauma #methylation #endocrinedisruptors #MaxPlanckInstitut

[ 23.11.2011
Auf YouTube antwortet #Kanzlerin #Merkel derzeit auf ausgewählte Fragen der User - drängendstes Thema laut Online-Abstimmung: #Drogenpolitik. ] https://youtu.be/y07JyniO0k4

#WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana

https://hanfverband.de/pressespiegel-zu-unserer-frage-an-merkel

#Streeck 🙏 #NinaWarken 🙏
#Merz #Söder #Klingbeil #Reiche 😀

#Cannabis #Gesundheit #Immunsystem #Endocannabinoidsystem #Epigenetik #epigenetics #trauma #methylation #endocrinedisruptors #MaxPlanckInstitut

#wissen #knowledge

Um #Alzheimer zu heilen, müssen wir die Ursachen der Krankheit entschlüsseln – ein langwieriger Prozess. Helfen Sie uns darum mit einer Fördermitgliedschaft. 🙏 https://www.alzheimer-forschung.de/forschung/forschungsprojekte/projektdatenbank/projekt/cannabinoids-as-neuroprotectants-and-modulators-of-the-processing-of-amyloid-precursor-protein-app/

#WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana

#Streeck 🙏 #NinaWarken 🙏
#Merz #Söder #Klingbeil #Reiche 😀

#Cannabis #Gesundheit #Immunsystem #Endocannabinoidsystem #Epigenetik #epigenetics #trauma #methylation #endocrinedisruptors #MaxPlanckInstitut

#SPD #FDP #CSU #CDU #GRÜNE #DIELINKE

Longevity is Carried In the Lysosome

Changes in Caenorhabditis elegans lysosome metabolism can be carried through generations via inherited histone modifications. A team of…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #epigenetics #Epigenomics #histonemodification #methylation #Science
https://www.newsbeep.com/us/205666/

#COMTGene #MentalHealth #GeneMutation #Methylation #GeneticTesting #BrainHealth #StressManagement #Prioritization #wellbeingatwork #wellbeingtips #wellnessurlaub #Neurocience #MentalWellbeing https://mastodon.social/@biohackingpathway/115321931400557471

@DaveWhittle

Overall, the researchers found that the mean amount of methylation varies greatly between tissues, ranging from 35% in the cervix, through to 48% in skin, 51% in muscle, 53% in the heart, 57% in the stomach and up to 63% in the retina.

#ageing
#methylation

#MTHFR #Genetics #Methylation #HealthTips #BrainHealth #LongevityDiet #LongevityLifestyle #NutritionalScience #Folate #Supplements #biohack #biohacking #biohacker #biohackingsecrets #biohackers #biohacks #WellnessJourney https://mastodon.social/@biohackingpathway/115019085061198331

🥦 +++ NICHT NUR FÜR EXPERTEN ODER EXPERTINNEN +++ ⚠️

[... #tobacco and #alcohol have large effects on genome wide DNA #methylation while

#marijuana consumption has 🙏 nonsignificant effects.

... related to #neurodevelopment, suggesting the mediation between recreational drug consumption and neurological disorders. ...] https://pubmed.ncbi.nlm.nih.gov/37216580/

#Methylierung #Janov #Epigenetik #Cannabis #Trauma #Traumata #Alkohol #FASD #Söder #Bayern #Streeck #NinaWarken #SPD #FDP #CSU #CDU #noAfD #DIELINKE

new track format in the ucsc GenomeBrowser: "bedMethyl and bigMethyl Track Format" https://genome.ucsc.edu/goldenPath/help/bedMethyl.html

" This format is useful for base-resolution methylation data generated by bisulfite sequencing or direct methylation detection methods such as long-read sequencing. By including both methylation level and support (coverage), bedMethyl provides a detailed view of methylation across the genome."

#methyl #ucsc #browser #methylation

DNA Methylation and Hydroxymethylation: The Molecular Switches of Gene Expression

#DNA #Epigenetics #GeneRegulation #Methylation #Hydroxymethylation #TET enzymes #DNARepair #Neuroscience #BrainHealth #Genetics #Cognition #Biology #MolecularBiology #GeneticResearch #NeuralPlasticity

https://youtube.com/shorts/5e4zK-AJutU?feature=share

Minimod preprint from @hasindu2008 gang is out. Code available https://github.com/warp9seq/minimod

I love the work they're doing with slow5/blow5 open spec for ONT raw data, and archive all internal reads using them. Really need to sit down and test this one out with my #archaea raw data!

#bioinformatics #methylation #ONT #sequencing

I've been down rabbit holes of research pertaining to the CBS gene and how it plays a role in sulfur pathways and methylation. Is there anything you know about the CBS gene that you'd like to share? I'd love papers to look at! #NEISVoid #MedSky #Genetics #Methylation

Our poster abstract for #ASMicrobe2025 is up! First bit of info from our warehouse lab led Haloarchaea study project. Session EEB-P-302 - EEB02 Saturday Microbial Evolution. Please feel free to come say hi 👋

#microbiology #archaea #sequencing #methylation

https://www.abstractsonline.com/pp8/#!/20974/presentation/3670

“So what has to happen is that methyltransferase has to hit that site over and over and over again, and it gradually builds up methylation … and only with repeated hits from the methyltransferase do we build up enough methylation that the gene actually gets silenced.” #DNA #isogg #Epigenetics #methylation #geneadons
https://www.chemistryworld.com/news/epigenetic-editors-enter-clinical-trials/4021267.article

@1goodtern on X wrote:

Ok folks.

You've maybe heard the word #Methylation recently, and while people are talking about it as if it's a big deal, you don't have the faintest idea what it means.

Let's change that.

🧵https://threadreaderapp.com/thread/1913957172716740847.html

#SarsCoV2 #Cancer #WearAMask

#Duckweed found to differentially mark old and new #transposons without #DNA #methylation .

#Spirodela #epigenetic #small_RNA

https://phys.org/news/2025-03-duckweed-differentially-transposons-dna-methylation.html

My monthly health update for my supporters to view is here: ko-fi.com/post/Health-... Thank you to all of my supporters for financing my mutual aid program and ensuring I can pay for the essentials of my care so that I can continue to give care to others! #MutualAid #selfcare #Methylation #MCAS

Health Update - Feb

SciTech Chronicles. . . . . . . . .Feb 13th, 2025

https://bit.ly/stc021325

#gravitationally-warped #NGC-6505 #space-time #Euclid #Mediterranean #KM3Net #ARCA #ORCA #microbiome #fermented #proximal #distal #mutations #epigenetic #DNA #methylation #cytosine #Bioink #SCOBY #nanocellulose #hydrogel

#Ancient #DNA #Methylation:
#Biologists Unlock Secrets of #HumanEvolution

https://scitechdaily.com/ancient-dna-methylation-biologists-unlock-secrets-of-human-evolution/

New Option for the Late-Stage Dimethylation of Arenes

Site-selective thianthrenation combined with with a Catellani reaction provides access to 3,5-dimethylated arenes

https://www.chemistryviews.org/new-option-for-the-late-stage-dimethylation-of-arenes/

#methylation #arenes #orgchem #chemistry #chemistryviews #chemviews

@lwpembleton @grrrck @adamhsparks @defuneste @danwwilson @milesmcbain @njtierney @jimjamslam the workstation at work (ubuntu 22, 24 cores, 125GB RAM memory, 2TB storage). Working very well for omics analysis #single_cell #scRNA, #methylation and #transcriptomics #ShareYourSetup

*Here, we report imitating methylation patterns rapidly in TXTL (IMPRINT), a generalized, rapid, and scalable approach based on cell-free transcription-translation (TXTL) to overcome DNA restriction, a prominent barrier to transformation. IMPRINT utilizes TXTL to express DNA methyltransferases from a bacterium’s restriction-modification systems. The expressed methyltransferases then methylate DNA in vitro to match the bacterium’s #DNA #methylation pattern"

https://www.sciencedirect.com/science/article/pii/S1097276524004817?via%3Dihub