#antidepressants — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #antidepressants, aggregated by home.social.
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Do people realize the latest evidence still suggests #exercise is about as effective as #psychotherapy and #antidepressants for treating #depression (and may result in fewer adverse events)?
Recent review:: https://doi.org/10.1002/14651858.CD004366.pub7
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Do people realize the latest evidence still suggests #exercise is about as effective as #psychotherapy and #antidepressants for treating #depression (and may result in fewer adverse events)?
Recent review:: https://doi.org/10.1002/14651858.CD004366.pub7
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REM-suppressing antidepressants linked to improved survival in ALS patients
Follow @1ban_news for daily coverage.
https://1ban.news/rem-suppressing-antidepressants-als-survival-fowler-2026/
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Antidepressant Shows Promise in Alleviating Long COVID Fatigue
📰 Original title: Common antidepressant may ease long COVID’s crushing fatigue
🤖 IA: It's not clickbait ✅
👥 Users: It's not clickbait ✅View full AI summary https://en.killbait.com/antidepressant-shows-promise-in-alleviating-long-covid-fatigue.html?utm_source=mastodon_world&utm_medium=social&utm_campaign=killbait.mastodon_world
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DATE: July 13, 2026 at 04:30AM
SOURCE: STAT NEWS MENTAL HEALTHTITLE: STAT+: HHS presses ahead with effort to curb antidepressant use
WASHINGTON — Health secretary Robert F. Kennedy Jr. is pressing forward with his effort to help Americans stop taking psychiatric drugs, a medical practice known as deprescribing.
Earlier this month, dozens of mental health professionals met with federal health officials to map out forthcoming clinical guidance they hope will help providers instruct patients on how to come off of antidepressant medications. While the Department of Health and Human Services has discussed plans to hold such a meeting, the outlines of the discussion haven’t been reported.
During those talks, they reviewed guidance from European nations and worked on recommendations for nonmedication-based options for patients to address their mental health, such as therapy. A senior HHS official said they discussed gaps in the research around deprescribing SSRIs, including the side effects a person may experience, which vary depending on the drug and how long the person was on it, and how to recognize the difference between those side effects and a return of a patient’s depressive symptoms.
Continue to STAT+ to read the full story…
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STAT News reports "from the frontiers of health and medicine".
Learn more at https://www.statnews.com/topic/mental-health/ .
See also their complete Mastodon account at @STAT .
This robot is NOT affiliated with STAT news and merely rebroadcasts from their site. Responses posted here are not monitored.
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Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
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#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #Deprescribing #Antidepressants #MentalHealthPolicy #HHS #RFKJrDeprescribing #SSRIs #NondrugTherapies #TherapyFirst #DepressionTreatment #PublicHealthGuidance
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DATE: July 13, 2026 at 04:30AM
SOURCE: STAT NEWS MENTAL HEALTHTITLE: STAT+: HHS presses ahead with effort to curb antidepressant use
WASHINGTON — Health secretary Robert F. Kennedy Jr. is pressing forward with his effort to help Americans stop taking psychiatric drugs, a medical practice known as deprescribing.
Earlier this month, dozens of mental health professionals met with federal health officials to map out forthcoming clinical guidance they hope will help providers instruct patients on how to come off of antidepressant medications. While the Department of Health and Human Services has discussed plans to hold such a meeting, the outlines of the discussion haven’t been reported.
During those talks, they reviewed guidance from European nations and worked on recommendations for nonmedication-based options for patients to address their mental health, such as therapy. A senior HHS official said they discussed gaps in the research around deprescribing SSRIs, including the side effects a person may experience, which vary depending on the drug and how long the person was on it, and how to recognize the difference between those side effects and a return of a patient’s depressive symptoms.
Continue to STAT+ to read the full story…
-------------------------------------------------
STAT News reports "from the frontiers of health and medicine".
Learn more at https://www.statnews.com/topic/mental-health/ .
See also their complete Mastodon account at @STAT .
This robot is NOT affiliated with STAT news and merely rebroadcasts from their site. Responses posted here are not monitored.
-------------------------------------------------
Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
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#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #Deprescribing #Antidepressants #MentalHealthPolicy #HHS #RFKJrDeprescribing #SSRIs #NondrugTherapies #TherapyFirst #DepressionTreatment #PublicHealthGuidance
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DATE: July 11, 2026 at 07:00AM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Antidepressants may normalize brain tissue changes caused by chronic depression
An experimental study of individuals suffering from persistent depressive disorder found that treatment with the antidepressants duloxetine and desvenlafaxine normalized tissue microstructure in parts of the brain. Symptom severity mediated the treatment effects on tissue microstructure, suggesting that abnormal tissue at the start of the study might be a compensatory response of the brain to depression symptoms. The paper was published in NeuroImage: Clinical.
Persistent depressive disorder, formerly called dysthymia, is a chronic condition in which low mood and related symptoms persist for at least two years in adults. Symptoms may include low energy, poor concentration, hopelessness, low self-esteem, sleep disturbance, appetite changes, and reduced enjoyment or motivation.
These symptoms may be less intense than those of a major depressive episode, but their long duration can substantially impair work, relationships, and quality of life. Some people with persistent depressive disorder also experience superimposed episodes of major depression, sometimes informally called “double depression.” The mainstream treatments involve psychotherapy, medication, or a combination of both.
Study author Ravi Bansal, a researcher affiliated with the University of Southern California and Children’s Hospital Los Angeles, and colleagues note that previous studies have reported changes to the microstructure of different cortical and subcortical regions of the brain in individuals suffering from persistent depressive disorder. Studies have also noted that people who experience a reduction of depressive symptoms or remission in response to antidepressant medication also tend to see the structural changes associated with depression returning to normal.
These, for example, include increased volume of the amygdala and hippocampus and thickening of the limbic cortex region of the brain in people who experience a remission or have milder clinical symptoms after treatment. In contrast, the volume of these areas declines and the cortex thins in individuals who do not remit or have more severe symptoms.
The researchers conducted a study in which they tracked brain microstructure changes in individuals suffering from persistent depression and treated with two different antidepressant drugs: duloxetine and desvenlafaxine.
Participants in the duloxetine study were 57 individuals suffering from persistent depression recruited from the New York State Psychiatric Institute. They were randomly divided into two groups. One group of 29 participants was assigned to receive duloxetine (30-120 mg/day) for 10 weeks. The other group of 28 participants was assigned to receive a placebo for the same period.
Participants in the desvenlafaxine study were 61 individuals recruited from local clinics, psychiatric listservs, hospital bulletin boards, newspapers, and Craigslist in the same geographical area as the first study. They were also randomly divided into two groups. One group of 31 participants was assigned to receive desvenlafaxine (50mg at the start, increased to 100mg per day after week four if participants tolerated the lower dose and were still depressed), while the remaining 30 participants received a placebo.
The studies also included 35 healthy individuals as an additional control group. Their average age was about 40 years, and 22 of them were men. This group did not differ from patients in the two studies in either average age or gender.
Participants completed magnetic resonance imaging scans of their brains before and after the treatment. However, a substantial share of participants did not complete these brain imaging procedures. Because the number of participants who completed these procedures was relatively small in the end, the study authors merged data from these two studies and analyzed them jointly for overlapping effects.
Results showed that duloxetine and desvenlafaxine led to unique changes in brain tissue microstructure in the dorsal prefrontal cortex. The study also revealed overlapping medication effects. Duloxetine and desvenlafaxine both led to the normalization of tissue microstructure in the limbic system. In contrast, tissue microstructure in participants who received a placebo tended to continue deviating further away from values for healthy participants.
Further analyses showed that symptom severity mediated the treatment effects on tissue microstructure. In other words, the treatments led to a reduction of symptoms, which, in turn, led to the normalization of brain tissue microstructure. This suggests that abnormal tissue microstructure at the start of the study is at least partly a compensatory neuroplastic response of the brain helping patients manage symptoms.
“Medication may have reduced the need for compensatory response because it reduces symptom severity, whereas placebo sustains the need for compensation. The unique and common effects of duloxetine and desvenlafaxine on neurotransmitter systems are likely responsible for their spatially unique and common effects in altering tissue microstructure,” the study authors concluded.
The study contributes to the scientific understanding of the effects of antidepressant medication on brain microstructure. However, it should be noted that around one in every three participants failed to complete the study or provide the needed data. This substantial attrition rate might have affected the results. Study authors also note that patients who were acutely suicidal or who had other medical and psychiatric conditions were excluded from participation, thereby limiting the generalizability of the findings.
The paper, “Effects of antidepressant medications on brain tissue microstructure in persistent depressive disorder across two randomized controlled trials,” was authored by Ravi Bansal, David J. Hellerstein, Siddhant Sawardekar, Ying Chen, and Bradley S. Peterson.
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Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
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#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #Antidepressants #BrainImaging #PersistentDepressiveDisorder #Duloxetine #Desvenlafaxine #NeuroImageClinical #BrainMicrostructure #DepressionTreatment #Neuroplasticity #MentalHealthResearch
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DATE: July 11, 2026 at 07:00AM
SOURCE: PSYPOST.ORG** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
-------------------------------------------------TITLE: Antidepressants may normalize brain tissue changes caused by chronic depression
An experimental study of individuals suffering from persistent depressive disorder found that treatment with the antidepressants duloxetine and desvenlafaxine normalized tissue microstructure in parts of the brain. Symptom severity mediated the treatment effects on tissue microstructure, suggesting that abnormal tissue at the start of the study might be a compensatory response of the brain to depression symptoms. The paper was published in NeuroImage: Clinical.
Persistent depressive disorder, formerly called dysthymia, is a chronic condition in which low mood and related symptoms persist for at least two years in adults. Symptoms may include low energy, poor concentration, hopelessness, low self-esteem, sleep disturbance, appetite changes, and reduced enjoyment or motivation.
These symptoms may be less intense than those of a major depressive episode, but their long duration can substantially impair work, relationships, and quality of life. Some people with persistent depressive disorder also experience superimposed episodes of major depression, sometimes informally called “double depression.” The mainstream treatments involve psychotherapy, medication, or a combination of both.
Study author Ravi Bansal, a researcher affiliated with the University of Southern California and Children’s Hospital Los Angeles, and colleagues note that previous studies have reported changes to the microstructure of different cortical and subcortical regions of the brain in individuals suffering from persistent depressive disorder. Studies have also noted that people who experience a reduction of depressive symptoms or remission in response to antidepressant medication also tend to see the structural changes associated with depression returning to normal.
These, for example, include increased volume of the amygdala and hippocampus and thickening of the limbic cortex region of the brain in people who experience a remission or have milder clinical symptoms after treatment. In contrast, the volume of these areas declines and the cortex thins in individuals who do not remit or have more severe symptoms.
The researchers conducted a study in which they tracked brain microstructure changes in individuals suffering from persistent depression and treated with two different antidepressant drugs: duloxetine and desvenlafaxine.
Participants in the duloxetine study were 57 individuals suffering from persistent depression recruited from the New York State Psychiatric Institute. They were randomly divided into two groups. One group of 29 participants was assigned to receive duloxetine (30-120 mg/day) for 10 weeks. The other group of 28 participants was assigned to receive a placebo for the same period.
Participants in the desvenlafaxine study were 61 individuals recruited from local clinics, psychiatric listservs, hospital bulletin boards, newspapers, and Craigslist in the same geographical area as the first study. They were also randomly divided into two groups. One group of 31 participants was assigned to receive desvenlafaxine (50mg at the start, increased to 100mg per day after week four if participants tolerated the lower dose and were still depressed), while the remaining 30 participants received a placebo.
The studies also included 35 healthy individuals as an additional control group. Their average age was about 40 years, and 22 of them were men. This group did not differ from patients in the two studies in either average age or gender.
Participants completed magnetic resonance imaging scans of their brains before and after the treatment. However, a substantial share of participants did not complete these brain imaging procedures. Because the number of participants who completed these procedures was relatively small in the end, the study authors merged data from these two studies and analyzed them jointly for overlapping effects.
Results showed that duloxetine and desvenlafaxine led to unique changes in brain tissue microstructure in the dorsal prefrontal cortex. The study also revealed overlapping medication effects. Duloxetine and desvenlafaxine both led to the normalization of tissue microstructure in the limbic system. In contrast, tissue microstructure in participants who received a placebo tended to continue deviating further away from values for healthy participants.
Further analyses showed that symptom severity mediated the treatment effects on tissue microstructure. In other words, the treatments led to a reduction of symptoms, which, in turn, led to the normalization of brain tissue microstructure. This suggests that abnormal tissue microstructure at the start of the study is at least partly a compensatory neuroplastic response of the brain helping patients manage symptoms.
“Medication may have reduced the need for compensatory response because it reduces symptom severity, whereas placebo sustains the need for compensation. The unique and common effects of duloxetine and desvenlafaxine on neurotransmitter systems are likely responsible for their spatially unique and common effects in altering tissue microstructure,” the study authors concluded.
The study contributes to the scientific understanding of the effects of antidepressant medication on brain microstructure. However, it should be noted that around one in every three participants failed to complete the study or provide the needed data. This substantial attrition rate might have affected the results. Study authors also note that patients who were acutely suicidal or who had other medical and psychiatric conditions were excluded from participation, thereby limiting the generalizability of the findings.
The paper, “Effects of antidepressant medications on brain tissue microstructure in persistent depressive disorder across two randomized controlled trials,” was authored by Ravi Bansal, David J. Hellerstein, Siddhant Sawardekar, Ying Chen, and Bradley S. Peterson.
-------------------------------------------------
Private, vetted email list for mental health professionals: https://www.clinicians-exchange.org
Unofficial Psychology Today Xitter to toot feed at Psych Today Unofficial Bot @PTUnofficialBot
-------------------------------------------------
#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #Antidepressants #BrainImaging #PersistentDepressiveDisorder #Duloxetine #Desvenlafaxine #NeuroImageClinical #BrainMicrostructure #DepressionTreatment #Neuroplasticity #MentalHealthResearch
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CW: Mental Health Update
Still going through ebbs and flows with antidepressant withdrawals. Still making progress, still moving in the right direction.
It’s been 3 months since my last dose of Zoloft. Having moments of feeling normal, but every 3-5 days have an emotional funk. Not as much depersonalization anymore thankfully.
Just have to ride the wave. Should be on another upswing by tomorrow. Gotta carry on.
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CW: Mental Health Update
Still going through ebbs and flows with antidepressant withdrawals. Still making progress, still moving in the right direction.
It’s been 3 months since my last dose of Zoloft. Having moments of feeling normal, but every 3-5 days have an emotional funk. Not as much depersonalization anymore thankfully.
Just have to ride the wave. Should be on another upswing by tomorrow. Gotta carry on.
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#RFKJr spreads nonsense about #antidepressants. The latest RFK Jr. Whopper of the Week from Defend Public Health https://www.defendpublichealth.org/opinion/whopper-week-kennedy-spreads-nonsense-about-antidepressants #ImpeachRFKJr
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#RFKJr spreads nonsense about #antidepressants. The latest RFK Jr. Whopper of the Week from Defend Public Health https://www.defendpublichealth.org/opinion/whopper-week-kennedy-spreads-nonsense-about-antidepressants #ImpeachRFKJr
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"you don't need to have a degree to know how dangerous #antidepressants are 😂😂😂"
"I'm not sure why we don't have an antidepressant crisis instead of an #OpioidCrisis."
"... the lie that there's a chemical imbalance in the brain that causes depression."
"If I listened to my doctor's I would be dead right now. The majority of #doctors don't even know what the drugs they prescribe do."
"Coming off #heroin not the same as coming off #SSRI... not even close... I'm a medical Dr"
[1/4]
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"you don't need to have a degree to know how dangerous #antidepressants are 😂😂😂"
"I'm not sure why we don't have an antidepressant crisis instead of an #OpioidCrisis."
"... the lie that there's a chemical imbalance in the brain that causes depression."
"If I listened to my doctor's I would be dead right now. The majority of #doctors don't even know what the drugs they prescribe do."
"Coming off #heroin not the same as coming off #SSRI... not even close... I'm a medical Dr"
[1/4]
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Antidepressants Under Scrutiny: Complex Debates Erupt Over Efficacy and Prescription
Robert F. Kennedy Jr. and Donald Trump's comments spark debate on antidepressant use. Experts explain why it's complex.
#antidepressants, #mentalhealth, #SSRIs, #RFKJr, #Trump
https://newsletter.tf/antidepressant-use-debated-after-political-statements/
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Antidepressants Under Scrutiny: Complex Debates Erupt Over Efficacy and Prescription
Robert F. Kennedy Jr. and Donald Trump's comments spark debate on antidepressant use. Experts explain why it's complex.
#antidepressants, #mentalhealth, #SSRIs, #RFKJr, #Trump
https://newsletter.tf/antidepressant-use-debated-after-political-statements/
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New calls to re-evaluate antidepressant use follow statements from political figures. Experts say the issue is more complex than just overmedication.
#antidepressants, #mentalhealth, #SSRIs, #RFKJr, #Trump
https://newsletter.tf/antidepressant-use-debated-after-political-statements/ -
New calls to re-evaluate antidepressant use follow statements from political figures. Experts say the issue is more complex than just overmedication.
#antidepressants, #mentalhealth, #SSRIs, #RFKJr, #Trump
https://newsletter.tf/antidepressant-use-debated-after-political-statements/ -
#RFKJr wants fewer people to take #antidepressants. There can be legitimate reasons for "deprescribing," a psychiatrist writes, but some of what Kennedy says is dangerously wrong. https://www.statnews.com/2026/05/13/antidepressant-deprescribing-kennedy-ssris/
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#RFKJr wants fewer people to take #antidepressants. There can be legitimate reasons for "deprescribing," a psychiatrist writes, but some of what Kennedy says is dangerously wrong. https://www.statnews.com/2026/05/13/antidepressant-deprescribing-kennedy-ssris/
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#MentalWealth #MentalHealth #GutHealth #Serotonin #Depression #Antidepressants #Wellbeing #MentalWellness #HealthAdvice #biohack #biohacking #biohacker #biohackingsecrets #GutHealthMatters #GutHealthy #GutHealthIsEverything #GutHealthDiet #GutHealthTips #GutHealthCoach #GaryBrecka #Tenex https://mastodon.social/@biohackingpathway/116559215705051526
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#MentalWealth #MentalHealth #GutHealth #Serotonin #Depression #Antidepressants #Wellbeing #MentalWellness #HealthAdvice #biohack #biohacking #biohacker #biohackingsecrets #GutHealthMatters #GutHealthy #GutHealthIsEverything #GutHealthDiet #GutHealthTips #GutHealthCoach #GaryBrecka #Tenex https://mastodon.social/@biohackingpathway/116559215705051526
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Prescribed Antidepressants Thwarted by Mitski
https://web.brid.gy/r/https://thehardtimes.net/music/prescribed-antidepressants-thwarted-by-mitski/
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Prescribed Antidepressants Thwarted by Mitski
https://web.brid.gy/r/https://thehardtimes.net/music/prescribed-antidepressants-thwarted-by-mitski/
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🚨🚨🚨 RFKJr’s “health” officials explored US #ban of some widely-used #antidepressants🚨🚨🚨
#US #health dept ofcls last week explored whether they could ban certain drugs in a widely prescribed class of #antidepressants as #HHS Secy #RFKJr prepared to roll out a plan to reduce their use….
Their interest centered on…selective serotonin reuptake inhibitors, or #SSRIs, such as #Zoloft, #Prozac & #Lexapro, which have been available in the US for decades….
#MentalHealth
https://www.reuters.com/business/healthcare-pharmaceuticals/kennedys-health-officials-explored-us-ban-some-widely-used-antidepressants-2026-05-08/?utm_source=braze&utm_medium=notifications&utm_campaign=2025_engagement -
🚨🚨🚨 RFKJr’s “health” officials explored US #ban of some widely-used #antidepressants🚨🚨🚨
#US #health dept ofcls last week explored whether they could ban certain drugs in a widely prescribed class of #antidepressants as #HHS Secy #RFKJr prepared to roll out a plan to reduce their use….
Their interest centered on…selective serotonin reuptake inhibitors, or #SSRIs, such as #Zoloft, #Prozac & #Lexapro, which have been available in the US for decades….
#MentalHealth
https://www.reuters.com/business/healthcare-pharmaceuticals/kennedys-health-officials-explored-us-ban-some-widely-used-antidepressants-2026-05-08/?utm_source=braze&utm_medium=notifications&utm_campaign=2025_engagement -
One thing they don't tell you (or perhaps know) about antidepressants is that you can and likely will continue to have the brain zaps later, even when you've stopped taking them for a while-- I'm talking months later. Not that antidepressants don't work- they can, and do. But just something to be prepared for.
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One thing they don't tell you (or perhaps know) about antidepressants is that you can and likely will continue to have the brain zaps later, even when you've stopped taking them for a while-- I'm talking months later. Not that antidepressants don't work- they can, and do. But just something to be prepared for.
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If you're prescribed #Sertraline in the UK, there has been a fuck-up with packaging by one manufacturer.
Affected boxes have blister packs of Citalopram in them instead of (or as well as) sertraline.
Make sure you double-check what you're taking:
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https://medicalxpress.com/news/2026-04-millions-birth-uncover-autism-surge.html
(if past is prologue US litigiousness will not take long to board this train, this time perhaps deservedly)
Prenatal exposure to medications that inhibit #sterol #biosynthesis, including certain #antidepressants, #antipsychotics, #betablockers, and #statins, is associated with a significantly increased risk of #autism spectrum disorder in offspring, with risk rising in a dose-dependent manner…pregnancies with such exposure increased from 4.3% in 2014 to 16.8% in 2023.
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https://medicalxpress.com/news/2026-04-millions-birth-uncover-autism-surge.html
(if past is prologue US litigiousness will not take long to board this train, this time perhaps deservedly)
Prenatal exposure to medications that inhibit #sterol #biosynthesis, including certain #antidepressants, #antipsychotics, #betablockers, and #statins, is associated with a significantly increased risk of #autism spectrum disorder in offspring, with risk rising in a dose-dependent manner…pregnancies with such exposure increased from 4.3% in 2014 to 16.8% in 2023.
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💊 Are psychedelics better than antidepressants? New study says no
https://medicalxpress.com/news/2026-03-psychedelics-antidepressants.html
#drugs #depression #mentalhealth #psychedelic #antidepressants #medicine #healthcare #clinical
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💊 Are psychedelics better than antidepressants? New study says no
https://medicalxpress.com/news/2026-03-psychedelics-antidepressants.html
#drugs #depression #mentalhealth #psychedelic #antidepressants #medicine #healthcare #clinical
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One of the stories I've been working on for my client Health & Her
Antidepressants Linked to Reduced Libido in Menopausal Women in the U.S., Experts Warn
#menopause #health #womenshealth #nutrition #antidepressants
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New research keeps contradicting #RFKJr's continuing torrent of bullshit. https://www.nbcnews.com/health/health-news/recent-studies-challenge-kennedys-claims-vaccines-tylenol-antidepressa-rcna259464
# vaccines #antidepressants #Tylenol
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War sends Russia into a spiral of antidepressants.
Sales of drugs to treat anxiety and other mental health issues have tripled since the pandemic, and grow every year.
In 2025, sales of antidepressants grew 36% compared to 2024.
#Russia #Antidepressants #MentalHealth #Anxiety #WarInUkraine #Health
