#dendritic — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #dendritic, aggregated by home.social.
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.
Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.
Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.
Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.
Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.
Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.
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https://krutonium.ca/posts/im-using-flake-parts-now/
New #Blog about #NixOS and #FlakeParts and honestly how good the #dendritic pattern is for Nix.
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https://krutonium.ca/posts/im-using-flake-parts-now/
New #Blog about #NixOS and #FlakeParts and honestly how good the #dendritic pattern is for Nix.
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https://krutonium.ca/posts/im-using-flake-parts-now/
New #Blog about #NixOS and #FlakeParts and honestly how good the #dendritic pattern is for Nix.
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https://krutonium.ca/posts/im-using-flake-parts-now/
New #Blog about #NixOS and #FlakeParts and honestly how good the #dendritic pattern is for Nix.
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https://krutonium.ca/posts/im-using-flake-parts-now/
New #Blog about #NixOS and #FlakeParts and honestly how good the #dendritic pattern is for Nix.
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(2/2)
For example, u might have to enable a service in both nixos option and home manager option for something. Like enabling KDE in nixos and then customising the options via home manager.
Usually one will write those in separate files. But in dendritic pattern u can actually make those in same file so that configs of same feature stays together to organise configs in better way.
I'm still figuring out too, so this is just my basic understanding so far 😅
#nix #nixos #dendritic #pattern -
@innocentzero
(1/2)
I'm a noob in that area. But here's my understanding:
It's a way in which evrything is a flake_parts module. That's all. It's not even a new tool or framework. It's just a practice.This way of structuring paves a lot of benefits when managing the systems.
The first steps would be to make everything as a flake_parts module and then start clubbing the configs based on feature.
#nix #nixos #dendritic #pattern -
🧠 New preprint by Lee et al.: Fast dendritic excitations primarily mediate #backpropagation in #CA1 pyramidal #neurons during #behavior
Using kHz #VoltageImaging across the full #dendritic tree, they show that fast dendritic spikes are usually driven by somatic #bAPs, not independently initiated. #bAP propagation into apical dendrites is contin. modulated by pre-spike dendritic voltage & can trigger slower plateau potentials linked to complex spikes.
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🧠 New preprint by Lee et al.: Fast dendritic excitations primarily mediate #backpropagation in #CA1 pyramidal #neurons during #behavior
Using kHz #VoltageImaging across the full #dendritic tree, they show that fast dendritic spikes are usually driven by somatic #bAPs, not independently initiated. #bAP propagation into apical dendrites is contin. modulated by pre-spike dendritic voltage & can trigger slower plateau potentials linked to complex spikes.
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🧠 New preprint by Lee et al.: Fast dendritic excitations primarily mediate #backpropagation in #CA1 pyramidal #neurons during #behavior
Using kHz #VoltageImaging across the full #dendritic tree, they show that fast dendritic spikes are usually driven by somatic #bAPs, not independently initiated. #bAP propagation into apical dendrites is contin. modulated by pre-spike dendritic voltage & can trigger slower plateau potentials linked to complex spikes.
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🧠 New preprint by Lee et al.: Fast dendritic excitations primarily mediate #backpropagation in #CA1 pyramidal #neurons during #behavior
Using kHz #VoltageImaging across the full #dendritic tree, they show that fast dendritic spikes are usually driven by somatic #bAPs, not independently initiated. #bAP propagation into apical dendrites is contin. modulated by pre-spike dendritic voltage & can trigger slower plateau potentials linked to complex spikes.
-
🧠 New preprint by Lee et al.: Fast dendritic excitations primarily mediate #backpropagation in #CA1 pyramidal #neurons during #behavior
Using kHz #VoltageImaging across the full #dendritic tree, they show that fast dendritic spikes are usually driven by somatic #bAPs, not independently initiated. #bAP propagation into apical dendrites is contin. modulated by pre-spike dendritic voltage & can trigger slower plateau potentials linked to complex spikes.
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🧠 Pastorelli et al. (2025) present a "simplified two-compartment #neuron with #CalciumDynamics capturing #brain-state-specific apical-amplification, -isolation and -drive". This Ca-#AdEx model replicates distinct #dendritic mechanisms across wakefulness, #NREM & #REM sleep using a compact ThetaPlanes transfer function. Cool implementation using the #NESTsimulator 💻!
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🧠 Pastorelli et al. (2025) present a "simplified two-compartment #neuron with #CalciumDynamics capturing #brain-state-specific apical-amplification, -isolation and -drive". This Ca-#AdEx model replicates distinct #dendritic mechanisms across wakefulness, #NREM & #REM sleep using a compact ThetaPlanes transfer function. Cool implementation using the #NESTsimulator 💻!
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🧠 Pastorelli et al. (2025) present a "simplified two-compartment #neuron with #CalciumDynamics capturing #brain-state-specific apical-amplification, -isolation and -drive". This Ca-#AdEx model replicates distinct #dendritic mechanisms across wakefulness, #NREM & #REM sleep using a compact ThetaPlanes transfer function. Cool implementation using the #NESTsimulator 💻!
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🧠 Pastorelli et al. (2025) present a "simplified two-compartment #neuron with #CalciumDynamics capturing #brain-state-specific apical-amplification, -isolation and -drive". This Ca-#AdEx model replicates distinct #dendritic mechanisms across wakefulness, #NREM & #REM sleep using a compact ThetaPlanes transfer function. Cool implementation using the #NESTsimulator 💻!
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🧠 Pastorelli et al. (2025) present a "simplified two-compartment #neuron with #CalciumDynamics capturing #brain-state-specific apical-amplification, -isolation and -drive". This Ca-#AdEx model replicates distinct #dendritic mechanisms across wakefulness, #NREM & #REM sleep using a compact ThetaPlanes transfer function. Cool implementation using the #NESTsimulator 💻!
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Dendritic patterns along the shore of Cobequid Bay in Nova Scotia. #photography #aerial #drone #novascotia #dronephotography #river #cobequidbay #dendritic #patterns #shore #landscape #shoreline #EastCoastKin
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Dendritic patterns on the mud flats of the Avon River at Windsor, Nova Scotia. #photography #dronephotography #aerialphotography #dendritic #patterns #geography #nature #windsor #novascotia #BayOfFundy #EastCoastKin
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#OpenSLS update: Generation of model #tissues with #dendritic #vascular networks via sacrificial #laser-sintered #carbohydrate templates: https://rdcu.be/b5tHy
Hardware designs: https://github.com/MillerLabFTW/OpenSLS
-R4: specialty powders for biomaterials research
-R3: nylon & wax #SLS-#Python add-on for #Blender to generate bifurcating vascular structures
#DIYbio #OpenSource #lab #3Dprinting #bioprinter #laser #hydrogel #instruments -
#OpenSLS update: Generation of model #tissues with #dendritic #vascular networks via sacrificial #laser-sintered #carbohydrate templates: https://rdcu.be/b5tHy
Hardware designs: https://github.com/MillerLabFTW/OpenSLS
-R4: specialty powders for biomaterials research
-R3: nylon & wax #SLS-#Python add-on for #Blender to generate bifurcating vascular structures
#DIYbio #OpenSource #lab #3Dprinting #bioprinter #laser #hydrogel #instruments -
#OpenSLS update: Generation of model #tissues with #dendritic #vascular networks via sacrificial #laser-sintered #carbohydrate templates: https://rdcu.be/b5tHy
Hardware designs: https://github.com/MillerLabFTW/OpenSLS
-R4: specialty powders for biomaterials research
-R3: nylon & wax #SLS-#Python add-on for #Blender to generate bifurcating vascular structures
#DIYbio #OpenSource #lab #3Dprinting #bioprinter #laser #hydrogel #instruments -
#OpenSLS update: Generation of model #tissues with #dendritic #vascular networks via sacrificial #laser-sintered #carbohydrate templates: https://rdcu.be/b5tHy
Hardware designs: https://github.com/MillerLabFTW/OpenSLS
-R4: specialty powders for biomaterials research
-R3: nylon & wax #SLS-#Python add-on for #Blender to generate bifurcating vascular structures
#DIYbio #OpenSource #lab #3Dprinting #bioprinter #laser #hydrogel #instruments -
#OpenSLS update: Generation of model #tissues with #dendritic #vascular networks via sacrificial #laser-sintered #carbohydrate templates: https://rdcu.be/b5tHy
Hardware designs: https://github.com/MillerLabFTW/OpenSLS
-R4: specialty powders for biomaterials research
-R3: nylon & wax #SLS-#Python add-on for #Blender to generate bifurcating vascular structures
#DIYbio #OpenSource #lab #3Dprinting #bioprinter #laser #hydrogel #instruments -
How can coronavirus infection cause uncontrolled, excessive inflammation?
Marta Bermejo-Jambrina, Teunis Geijtenbeek et al show that #SarsCoV2 opsonization by the complement system induces interferon responses from #dendritic cells, which require control by antiviral antibodieshttps://www.embopress.org/doi/full/10.1038/s44318-024-00061-0
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MICa/b-dependent activation of natural killer cells by CD64+ inflammatory type 2 dendritic cells contributes to #autoimmunity
Pathology of primary Sjögren's syndrome is known to involve #interferons, but Enrique Martin-Gayo et al @UAM_Medicina show additional roles also for #innateimmune cells like natural killer and #dendritic cells
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What is going on with our immune cells after COVID-19 infection?
This thread will explore some of the impacts of #COVID #infection on our #immune system even after people are recovered including:
- Missing naive #T-cells
- Exhausted T-cells
- Loss of #B-cell maturation
- Hyper-activated #inflammatory response
- Immune system is impeded post-infection
- #Immunological #dysfunction persists 8+ months
- #Depletion and dysfunction of #dendritic cells🧵 1/
