#synapticplasticity — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #synapticplasticity, aggregated by home.social.
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.
Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.
Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.
Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.
Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.
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🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.
Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.
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🧠 Synaptic plasticity is how your brain physically encodes memory. And its decline may be at the core of cognitive aging.
#Neuroscience #SynapticPlasticity #AgingResearch #Longevity #MolecularBiology #Neurology #BrainHealth #Hallmarks #CognitiveDecline #LifeSciences
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https://www.europesays.com/ie/335667/ Neural Afterburn: Brain Rewires Itself to Boost Endurance #BrainPlasticity #Éire #EnduranceTraining #Exercise #Fitness #Health #Hypothalamus #IE #Ireland #MetabolicHealth #NeuralCircuits #neuroplasticity #Neuroscience #SF1Neurons #SynapticPlasticity #UniversityOfPennsylvania
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🧠 New preprint by Zhong et al. proposes a #synaptic mechanism for #chunking in #WorkingMemory.
Using short-term #plasticity and synaptic augmentation, their model shows how items can be temporarily suppressed and later retrieved as chunks, increasing effective capacity w/o increasing simultaneous activity.
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🧠 New preprint by Zhong et al. proposes a #synaptic mechanism for #chunking in #WorkingMemory.
Using short-term #plasticity and synaptic augmentation, their model shows how items can be temporarily suppressed and later retrieved as chunks, increasing effective capacity w/o increasing simultaneous activity.
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🧠 New preprint by Zhong et al. proposes a #synaptic mechanism for #chunking in #WorkingMemory.
Using short-term #plasticity and synaptic augmentation, their model shows how items can be temporarily suppressed and later retrieved as chunks, increasing effective capacity w/o increasing simultaneous activity.
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🧠 New preprint by Zhong et al. proposes a #synaptic mechanism for #chunking in #WorkingMemory.
Using short-term #plasticity and synaptic augmentation, their model shows how items can be temporarily suppressed and later retrieved as chunks, increasing effective capacity w/o increasing simultaneous activity.
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🧠 New preprint by Zhong et al. proposes a #synaptic mechanism for #chunking in #WorkingMemory.
Using short-term #plasticity and synaptic augmentation, their model shows how items can be temporarily suppressed and later retrieved as chunks, increasing effective capacity w/o increasing simultaneous activity.
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https://www.europesays.com/ie/234700/ RNA editing study finds many ways for neurons to diversify | MIT News #ADAR #AndresCrane #CellularAndMolecularBiology #complexin #Éire #GlutamateRelease #IE #Ireland #MITBCS #MITBiology #MITPicowerInstitute #NonCanonicalEdits #RNAEditing #RNATranscripts #Science #SynapticPlasticity #TroyLittleton
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An organism's internal state & behavioral outcomes are shaped by experience. This study reveals a #neuropeptide relay pathway, neuronal & non-neuronal, which orchestrates #SynapticPlasticity & context-dependent shifts in #mating duration in male #Drosophila @PLOSBiology https://plos.io/4n8aUSV
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🌀 Could a protein that twists into filaments reveal how cells keep themselves in balance?
🔗 Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.018
📚 CSBJ: https://www.csbj.org/
#StructuralBiology #CryoEM #Thorase #MolecularBiology #mTORC1 #ProteinStructure #Biophysics #AAAplusATPase #SynapticPlasticity #Mitochondria
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🌀 Could a protein that twists into filaments reveal how cells keep themselves in balance?
🔗 Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.018
📚 CSBJ: https://www.csbj.org/
#StructuralBiology #CryoEM #Thorase #MolecularBiology #mTORC1 #ProteinStructure #Biophysics #AAAplusATPase #SynapticPlasticity #Mitochondria
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🌀 Could a protein that twists into filaments reveal how cells keep themselves in balance?
🔗 Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.018
📚 CSBJ: https://www.csbj.org/
#StructuralBiology #CryoEM #Thorase #MolecularBiology #mTORC1 #ProteinStructure #Biophysics #AAAplusATPase #SynapticPlasticity #Mitochondria
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The Brain’s Rewiring Power: Understanding Activity-Dependent Synaptic Changes
#BrainScience #Neuroplasticity #MemoryAndLearning #Neuroscience #BrainHealth #SynapticPlasticity #MindAndBrain #NeuralNetworks #CognitiveScience #BrainRecovery
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The Brain’s Rewiring Power: Understanding Activity-Dependent Synaptic Changes
#BrainScience #Neuroplasticity #MemoryAndLearning #Neuroscience #BrainHealth #SynapticPlasticity #MindAndBrain #NeuralNetworks #CognitiveScience #BrainRecovery
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The Brain’s Rewiring Power: Understanding Activity-Dependent Synaptic Changes
#BrainScience #Neuroplasticity #MemoryAndLearning #Neuroscience #BrainHealth #SynapticPlasticity #MindAndBrain #NeuralNetworks #CognitiveScience #BrainRecovery
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The Brain’s Rewiring Power: Understanding Activity-Dependent Synaptic Changes
#BrainScience #Neuroplasticity #MemoryAndLearning #Neuroscience #BrainHealth #SynapticPlasticity #MindAndBrain #NeuralNetworks #CognitiveScience #BrainRecovery
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The Brain’s Rewiring Power: Understanding Activity-Dependent Synaptic Changes
#BrainScience #Neuroplasticity #MemoryAndLearning #Neuroscience #BrainHealth #SynapticPlasticity #MindAndBrain #NeuralNetworks #CognitiveScience #BrainRecovery
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From Neurotransmitters to Kinases: The Chemistry Powerhouse of Your Brain
#BrainChemistry #Neuroscience #Neurobiology #BrainFacts #SynapticPlasticity #Neurotransmitters #ProteinKinaseC #MemoryAndLearning #BrainHealth #ScienceExplained
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From Neurotransmitters to Kinases: The Chemistry Powerhouse of Your Brain
#BrainChemistry #Neuroscience #Neurobiology #BrainFacts #SynapticPlasticity #Neurotransmitters #ProteinKinaseC #MemoryAndLearning #BrainHealth #ScienceExplained
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From Neurotransmitters to Kinases: The Chemistry Powerhouse of Your Brain
#BrainChemistry #Neuroscience #Neurobiology #BrainFacts #SynapticPlasticity #Neurotransmitters #ProteinKinaseC #MemoryAndLearning #BrainHealth #ScienceExplained
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From Neurotransmitters to Kinases: The Chemistry Powerhouse of Your Brain
#BrainChemistry #Neuroscience #Neurobiology #BrainFacts #SynapticPlasticity #Neurotransmitters #ProteinKinaseC #MemoryAndLearning #BrainHealth #ScienceExplained
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From Neurotransmitters to Kinases: The Chemistry Powerhouse of Your Brain
#BrainChemistry #Neuroscience #Neurobiology #BrainFacts #SynapticPlasticity #Neurotransmitters #ProteinKinaseC #MemoryAndLearning #BrainHealth #ScienceExplained
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How Your Brain Forms Memories: The Science of Synaptic Plasticity
#BrainScience #Neuroscience #Memory #Learning #SynapticPlasticity #Neurons #BrainHealth #LTP #Neurobiology #MindAndBrain
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How Your Brain Forms Memories: The Science of Synaptic Plasticity
#BrainScience #Neuroscience #Memory #Learning #SynapticPlasticity #Neurons #BrainHealth #LTP #Neurobiology #MindAndBrain
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How Your Brain Forms Memories: The Science of Synaptic Plasticity
#BrainScience #Neuroscience #Memory #Learning #SynapticPlasticity #Neurons #BrainHealth #LTP #Neurobiology #MindAndBrain
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How Your Brain Forms Memories: The Science of Synaptic Plasticity
#BrainScience #Neuroscience #Memory #Learning #SynapticPlasticity #Neurons #BrainHealth #LTP #Neurobiology #MindAndBrain
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How Your Brain Forms Memories: The Science of Synaptic Plasticity
#BrainScience #Neuroscience #Memory #Learning #SynapticPlasticity #Neurons #BrainHealth #LTP #Neurobiology #MindAndBrain
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📖 Vaidya et al. investigate how #hippocampal #CA1 #PlaceCells form expanding #memory representations over days. Using longitudinal in vivo recordings, they show that stable #PlaceFields progressively emerge as active cells increase their likelihood of remaining active across sessions. This gradual stabilization hinges on #behavioral‑timescale #SynapticPlasticity, offering a new model of how CA1 memories solidify w/o #CatastrophicOverwriting.
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📖 Vaidya et al. investigate how #hippocampal #CA1 #PlaceCells form expanding #memory representations over days. Using longitudinal in vivo recordings, they show that stable #PlaceFields progressively emerge as active cells increase their likelihood of remaining active across sessions. This gradual stabilization hinges on #behavioral‑timescale #SynapticPlasticity, offering a new model of how CA1 memories solidify w/o #CatastrophicOverwriting.
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📖 Vaidya et al. investigate how #hippocampal #CA1 #PlaceCells form expanding #memory representations over days. Using longitudinal in vivo recordings, they show that stable #PlaceFields progressively emerge as active cells increase their likelihood of remaining active across sessions. This gradual stabilization hinges on #behavioral‑timescale #SynapticPlasticity, offering a new model of how CA1 memories solidify w/o #CatastrophicOverwriting.
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📖 Vaidya et al. investigate how #hippocampal #CA1 #PlaceCells form expanding #memory representations over days. Using longitudinal in vivo recordings, they show that stable #PlaceFields progressively emerge as active cells increase their likelihood of remaining active across sessions. This gradual stabilization hinges on #behavioral‑timescale #SynapticPlasticity, offering a new model of how CA1 memories solidify w/o #CatastrophicOverwriting.
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📖 Vaidya et al. investigate how #hippocampal #CA1 #PlaceCells form expanding #memory representations over days. Using longitudinal in vivo recordings, they show that stable #PlaceFields progressively emerge as active cells increase their likelihood of remaining active across sessions. This gradual stabilization hinges on #behavioral‑timescale #SynapticPlasticity, offering a new model of how CA1 memories solidify w/o #CatastrophicOverwriting.
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"A unifying mechanism for presynaptic homeostatic plasticity at mammalian peripheral and central synapses", Chipman et al. 2025 (Graeme Davis lab).
https://www.cell.com/neuron/fulltext/S0896-6273(25)00430-1. (Open access)"Sema3a-PHP redistributes vesicles from a non-releasing to the release-ready pool"
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Recently, we discussed this insightful paper by Squadrani et al (2024) in our #JournalClub. It explores how #astrocytes enhance #SynapticPlasticity during #ReversalLearning by modulating D-serine levels, providing a #biophysical basis for dynamic #LTP thresholds. The findings suggest astrocytic signaling is crucial for #AdaptiveLearning, linking #glial activity to #behavioral flexibility. Here’s a summary from our JC:
🌍 https://www.fabriziomusacchio.com/blog/2025-06-29-astrocyte_enhance_plasticity/
📝 https://doi.org/10.1038/s42003-024-06540-8 -
Recently, we discussed this insightful paper by Squadrani et al (2024) in our #JournalClub. It explores how #astrocytes enhance #SynapticPlasticity during #ReversalLearning by modulating D-serine levels, providing a #biophysical basis for dynamic #LTP thresholds. The findings suggest astrocytic signaling is crucial for #AdaptiveLearning, linking #glial activity to #behavioral flexibility. Here’s a summary from our JC:
🌍 https://www.fabriziomusacchio.com/blog/2025-06-29-astrocyte_enhance_plasticity/
📝 https://doi.org/10.1038/s42003-024-06540-8 -
Recently, we discussed this insightful paper by Squadrani et al (2024) in our #JournalClub. It explores how #astrocytes enhance #SynapticPlasticity during #ReversalLearning by modulating D-serine levels, providing a #biophysical basis for dynamic #LTP thresholds. The findings suggest astrocytic signaling is crucial for #AdaptiveLearning, linking #glial activity to #behavioral flexibility. Here’s a summary from our JC:
🌍 https://www.fabriziomusacchio.com/blog/2025-06-29-astrocyte_enhance_plasticity/
📝 https://doi.org/10.1038/s42003-024-06540-8 -
Recently, we discussed this insightful paper by Squadrani et al (2024) in our #JournalClub. It explores how #astrocytes enhance #SynapticPlasticity during #ReversalLearning by modulating D-serine levels, providing a #biophysical basis for dynamic #LTP thresholds. The findings suggest astrocytic signaling is crucial for #AdaptiveLearning, linking #glial activity to #behavioral flexibility. Here’s a summary from our JC:
🌍 https://www.fabriziomusacchio.com/blog/2025-06-29-astrocyte_enhance_plasticity/
📝 https://doi.org/10.1038/s42003-024-06540-8 -
Recently, we discussed this insightful paper by Squadrani et al (2024) in our #JournalClub. It explores how #astrocytes enhance #SynapticPlasticity during #ReversalLearning by modulating D-serine levels, providing a #biophysical basis for dynamic #LTP thresholds. The findings suggest astrocytic signaling is crucial for #AdaptiveLearning, linking #glial activity to #behavioral flexibility. Here’s a summary from our JC:
🌍 https://www.fabriziomusacchio.com/blog/2025-06-29-astrocyte_enhance_plasticity/
📝 https://doi.org/10.1038/s42003-024-06540-8 -
From Stress to Mood: The Neuroendocrine and Immune Interplay in Your Brain
#BrainScience #Neuroscience #SynapticPlasticity #Neurons #BrainChemistry #Optogenetics #Neurotransmitters #BrainHealth #MentalHealth #NeuralNetworks #BrainMetabolism #Neuroimmune #BrainResearch #MindAndBody #BrainInnovation
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Signal Transduction and Synaptic Plasticity: Keys to Learning and Mood
#Neuroscience #BrainScience #HumanBody #Neurobiology #SynapticPlasticity #Hormones #NervousSystem #CellBiology #MindAndBody #ScienceExploration #MedicalScience #Neurons #BrainHealth #Physiology #ScientificDiscovery
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https://www.europesays.com/uk/128434/ Boosting Ketamine’s Antidepressant Effects to Last Two Months #Antidepressants #BrainResearch #Depression #Erk #Health #ketamine #MentalHealth #neurobiology #Neuroscience #Psychology #psychopharmacology #SynapticPlasticity #UK #UnitedKingdom #VanderbiltUniversity
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How Neurons, Hormones, and Systems Collaborate to Power Your Feelings and Movements
#Neuroscience #BrainAndBody #ScienceExploration #Neurons #SynapticPlasticity #Hormones # NervousSystem #CellBiology #BrainFunctions #MindAndBody #MedicalScience #LearningAndMemory #Neurotransmitters #BrainHealth #ScienceEducation
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The Dance of Relationships: Navigating Mental Health and Connection
#Relationships #MentalHealth #DyadicCoping #EmotionalSupport #Connection #Anxiety #SynapticPlasticity #LoveAndFriendship #TugOfWar #Harmony #Compassion #InterpersonalDynamics #MentalWellness #SupportSystem #DanceOfLife
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The Dance of Relationships: Navigating Mental Health and Connection
#Relationships #MentalHealth #DyadicCoping #EmotionalSupport #Connection #Anxiety #SynapticPlasticity #LoveAndFriendship #TugOfWar #Harmony #Compassion #InterpersonalDynamics #MentalWellness #SupportSystem #DanceOfLife
