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#synapses — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #synapses, aggregated by home.social.

  1. 🧠 New paper from our neighboring Gründemann Lab @dzne 👋

    Chloé Maëlle Benoit and colleagues show that #axon initial segments in #mPFC #neurons undergo #learning-dependent #StructuralPlasticity during fear extinction, linking #AIS dynamics to #MemoryFormation in vivo. A very cool study that extends the concept of learning-related #plasticity beyond #synapses to intrinsic neuronal compartments.

    🌍 doi.org/10.1038/s41593-025-021

    #Neuroscience #DZNE

  2. 🧠 New pre-print by Wiesner et al. (2025) shows non-#synaptic #exocytosis directly from the #axon shaft, regulated by the submembrane periodic skeleton. Using #superresolution #imaging and live assays (#HiLo (VAMP2-pHluorin), #SIM, and correlative two-color #SMLM/ #STORM) they reveal that #axons can release vesicles outside classical #synapses, expanding how we understand #neuronal communication and #AxonalSignaling.

    🌍 doi.org/10.1101/2025.09.17.676

    #Neuroscience