#biorxiv — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #biorxiv, aggregated by home.social.
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New preprint from the lab!
How do brain progenitors choose between D1 and D2 medium spiny neurons? We find the *relative levels* of SP9 and DLX TFs tip the balance: SP9 activates D2 genes at promoters, and represses D1 enhancers via DLX/NuRD.
Proud of the team — combining sparse in vivo CRISPR, lineage barcoding, scRNA-seq, ChIP-seq, CUT&RUN and proteomics for mechanistic depth in in vivo functional genomics.
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///Biorxiv///
Le serveur de prépublications scientifiques pour la biologie !
https://www.biorxiv.org/
Plus de ressources libres sur https://www.libresites.org
#serveur #prépublications #scientifique #science #biologie #biorxiv -
" Instead, #Hepatoblastoma #tumors contain a large suppressive #myeloid compartment which poses opportunities for targeting. Specifically, therapeutic antibodies
targeting the #tumor antigen #GPC3 to induce ADCP by #macrophages, in combination with myeloid
#ImmuneCheckpointBlockade (#CD47/SIRPa, or VISTA) could be a feasible strategy to explore in future studies"Krijgsman et al. from Vercoulen lab in the #UMCUtrecht, on #bioRXiv:
https://www.biorxiv.org/content/10.1101/2023.06.28.546852v1 -
https://www.biorxiv.org/content/10.1101/2023.04.26.538077v1 Benchmarking of virus detection methods from WGS data. PPR-Meta seems best in environmental samples, while VirSorter2 is best in the gut. Which is good, because VirSorter2 is what we're using at the moment in the @BorkLab 😅
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A new #preprint #OpenScience #PeerReview by #PCI_Infections: Fritz M, et al (2023) African #armyants at the forefront of #virome surveillance in a remote #tropicalforest. #bioRxiv, #Infections https://doi.org/10.1101/2022.12.13.520061