#cortical — Public Fediverse posts

🧠 New paper by Pachitariu … @computingnature: spontaneous brainwide activity in mice shows macroscopic coordination that resembles linear dynamics driven by a critically normalized random symmetric matrix.

#Cortical and brainwide recordings showed power-law variance spectra, slow global activity modes, and little rotational structure, unlike #CA1, which looked closer to an efficient, less correlated code.

🌍 https://doi.org/10.1038/s41586-026-10528-1

#Neuroscience #CompNeuro #NeuralDynamics

🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience

🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience

🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience

🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience

🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience

🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.

Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.

🌍 https://doi.org/10.1016/j.neuron.2026.04.017

#Neuroscience #CompNeuro

🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.

Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.

🌍 https://doi.org/10.1016/j.neuron.2026.04.017

#Neuroscience #CompNeuro

🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.

Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.

🌍 https://doi.org/10.1016/j.neuron.2026.04.017

#Neuroscience #CompNeuro

🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.

Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.

🌍 https://doi.org/10.1016/j.neuron.2026.04.017

#Neuroscience #CompNeuro

🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.

Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.

🌍 https://doi.org/10.1016/j.neuron.2026.04.017

#Neuroscience #CompNeuro

RE: https://fediscience.org/@PLOSBiology/116579076475476559

🧠 Interesting new work on #cortical #PopulationCoding: Revah, Wolf, Gutnick & Neef show that the #encoding performance of cortical #neurons is not determined by single-cell properties alone, but by a combination of #dendrite size, #synaptic noise statistics, ion channels, and population size.

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RE: https://fediscience.org/@PLOSBiology/116579076475476559

🧠 Interesting new work on #cortical #PopulationCoding: Revah, Wolf, Gutnick & Neef show that the #encoding performance of cortical #neurons is not determined by single-cell properties alone, but by a combination of #dendrite size, #synaptic noise statistics, ion channels, and population size.

🧵1/2

RE: https://fediscience.org/@PLOSBiology/116579076475476559

🧠 Interesting new work on #cortical #PopulationCoding: Revah, Wolf, Gutnick & Neef show that the #encoding performance of cortical #neurons is not determined by single-cell properties alone, but by a combination of #dendrite size, #synaptic noise statistics, ion channels, and population size.

🧵1/2

RE: https://fediscience.org/@PLOSBiology/116579076475476559

🧠 Interesting new work on #cortical #PopulationCoding: Revah, Wolf, Gutnick & Neef show that the #encoding performance of cortical #neurons is not determined by single-cell properties alone, but by a combination of #dendrite size, #synaptic noise statistics, ion channels, and population size.

🧵1/2

RE: https://fediscience.org/@PLOSBiology/116579076475476559

🧠 Interesting new work on #cortical #PopulationCoding: Revah, Wolf, Gutnick & Neef show that the #encoding performance of cortical #neurons is not determined by single-cell properties alone, but by a combination of #dendrite size, #synaptic noise statistics, ion channels, and population size.

🧵1/2

🧠 New preprint by Garcia-Garcia et al.: The authors show that cerebellar #GranuleCells do not simply expand #cortical activity into a high-dimensional code. Instead, they preserve low-dimensional cortical #manifold geometry while reorienting it across contexts. This rotation separates similar tasks, reduces interference, and supports flexible dual-task learning.

📄 https://www.biorxiv.org/content/10.64898/2026.03.03.709240v1.full.pdf

#Neuroscience #NeuralDynamics #CompNeuro

🧠 New preprint by Garcia-Garcia et al.: The authors show that cerebellar #GranuleCells do not simply expand #cortical activity into a high-dimensional code. Instead, they preserve low-dimensional cortical #manifold geometry while reorienting it across contexts. This rotation separates similar tasks, reduces interference, and supports flexible dual-task learning.

📄 https://www.biorxiv.org/content/10.64898/2026.03.03.709240v1.full.pdf

#Neuroscience #NeuralDynamics #CompNeuro

🧠 New preprint by Garcia-Garcia et al.: The authors show that cerebellar #GranuleCells do not simply expand #cortical activity into a high-dimensional code. Instead, they preserve low-dimensional cortical #manifold geometry while reorienting it across contexts. This rotation separates similar tasks, reduces interference, and supports flexible dual-task learning.

📄 https://www.biorxiv.org/content/10.64898/2026.03.03.709240v1.full.pdf

#Neuroscience #NeuralDynamics #CompNeuro

🧠 New preprint by Garcia-Garcia et al.: The authors show that cerebellar #GranuleCells do not simply expand #cortical activity into a high-dimensional code. Instead, they preserve low-dimensional cortical #manifold geometry while reorienting it across contexts. This rotation separates similar tasks, reduces interference, and supports flexible dual-task learning.

📄 https://www.biorxiv.org/content/10.64898/2026.03.03.709240v1.full.pdf

#Neuroscience #NeuralDynamics #CompNeuro

🧠 New preprint by Garcia-Garcia et al.: The authors show that cerebellar #GranuleCells do not simply expand #cortical activity into a high-dimensional code. Instead, they preserve low-dimensional cortical #manifold geometry while reorienting it across contexts. This rotation separates similar tasks, reduces interference, and supports flexible dual-task learning.

📄 https://www.biorxiv.org/content/10.64898/2026.03.03.709240v1.full.pdf

#Neuroscience #NeuralDynamics #CompNeuro

Are 200,000 Human Cells in a Petri Dish Really Playing DOOM? Pump the Brakes https://lowendbox.com/blog/are-200000-human-cells-in-a-petri-dish-really-playing-doom-pump-the-brakes/ #Editorial&News #corticallabs #cortical #doom #cl1

「活體」伺服器：科學家培養「迷你人腦」為電腦提供動力

BBC News 中文 2025-10-08 14:00:00 CST

Cortical development in #primates follows a hierarchical gradient, but how does this vary between species? This study shows that #humans & #macaques share conserved maturation patterns, with humans exhibiting prolonged #cortical development @PLOSBiology https://plos.io/4prEO65

🧠 New study by Lempel et al. (2025): Visual experience after eye opening aligns #feedforward inputs (L4) and #RecurrentNetworks (L2/3) in mouse #VisualCortex. This improved alignment, together with enhanced orientation discrimination, creates coherent, reliable sensory codes, revealing how experience shapes stable #cortical representations:

🌍 https://doi.org/10.1016/j.neuron.2025.09.012

#Neuroscience #CompNeuro #Plasticity #CorticalCircuits

🧠 New study by Lempel et al. (2025): Visual experience after eye opening aligns #feedforward inputs (L4) and #RecurrentNetworks (L2/3) in mouse #VisualCortex. This improved alignment, together with enhanced orientation discrimination, creates coherent, reliable sensory codes, revealing how experience shapes stable #cortical representations:

🌍 https://doi.org/10.1016/j.neuron.2025.09.012

#Neuroscience #CompNeuro #Plasticity #CorticalCircuits

🧠 New study by Lempel et al. (2025): Visual experience after eye opening aligns #feedforward inputs (L4) and #RecurrentNetworks (L2/3) in mouse #VisualCortex. This improved alignment, together with enhanced orientation discrimination, creates coherent, reliable sensory codes, revealing how experience shapes stable #cortical representations:

🌍 https://doi.org/10.1016/j.neuron.2025.09.012

#Neuroscience #CompNeuro #Plasticity #CorticalCircuits

🧠 New study by Lempel et al. (2025): Visual experience after eye opening aligns #feedforward inputs (L4) and #RecurrentNetworks (L2/3) in mouse #VisualCortex. This improved alignment, together with enhanced orientation discrimination, creates coherent, reliable sensory codes, revealing how experience shapes stable #cortical representations:

🌍 https://doi.org/10.1016/j.neuron.2025.09.012

#Neuroscience #CompNeuro #Plasticity #CorticalCircuits

🧠 New study by Lempel et al. (2025): Visual experience after eye opening aligns #feedforward inputs (L4) and #RecurrentNetworks (L2/3) in mouse #VisualCortex. This improved alignment, together with enhanced orientation discrimination, creates coherent, reliable sensory codes, revealing how experience shapes stable #cortical representations:

🌍 https://doi.org/10.1016/j.neuron.2025.09.012

#Neuroscience #CompNeuro #Plasticity #CorticalCircuits

📚 New preprint by Song et al.: Geometry of #NeuralDynamics along the #cortical #attractor landscape reflects changes in attention. They show that while attractor positions are determined by cortical organization, the geometry of neural dynamics on the landscape changes systematically with attentional states and contexts.

🌍 https://www.biorxiv.org/content/10.1101/2025.08.08.669432v1

#Neuroscience #Attention #fMRI #CompNeuro

Echte #Intelligenz:

#Menschliche #Neuronen als #biologischer #Computer verfügbar.

#Lebende #Nervenzellen auf einem Chip imitieren die Funktion des Gehirns. Ein Einsatz für #KI-Beschleunigung und Bitcoin-Mining ist denkbar.

Das australische #Start-up #Cortical #Labs hat mit #CL1 einen #Computer vorgestellt, in dem 800.000 menschliche #Nervenzellen auf einem #Siliziumchip für die #Informationsübertragung genutzt werden.

https://www.golem.de/news/echte-intelligenz-menschliche-neuronen-als-biologischer-computer-verfuegbar-2506-196982.html

Echte #Intelligenz:

#Menschliche #Neuronen als #biologischer #Computer verfügbar.

#Lebende #Nervenzellen auf einem Chip imitieren die Funktion des Gehirns. Ein Einsatz für #KI-Beschleunigung und Bitcoin-Mining ist denkbar.

Das australische #Start-up #Cortical #Labs hat mit #CL1 einen #Computer vorgestellt, in dem 800.000 menschliche #Nervenzellen auf einem #Siliziumchip für die #Informationsübertragung genutzt werden.

https://www.golem.de/news/echte-intelligenz-menschliche-neuronen-als-biologischer-computer-verfuegbar-2506-196982.html

Echte #Intelligenz:

#Menschliche #Neuronen als #biologischer #Computer verfügbar.

#Lebende #Nervenzellen auf einem Chip imitieren die Funktion des Gehirns. Ein Einsatz für #KI-Beschleunigung und Bitcoin-Mining ist denkbar.

Das australische #Start-up #Cortical #Labs hat mit #CL1 einen #Computer vorgestellt, in dem 800.000 menschliche #Nervenzellen auf einem #Siliziumchip für die #Informationsübertragung genutzt werden.

https://www.golem.de/news/echte-intelligenz-menschliche-neuronen-als-biologischer-computer-verfuegbar-2506-196982.html

Echte #Intelligenz:

#Menschliche #Neuronen als #biologischer #Computer verfügbar.

#Lebende #Nervenzellen auf einem Chip imitieren die Funktion des Gehirns. Ein Einsatz für #KI-Beschleunigung und Bitcoin-Mining ist denkbar.

Das australische #Start-up #Cortical #Labs hat mit #CL1 einen #Computer vorgestellt, in dem 800.000 menschliche #Nervenzellen auf einem #Siliziumchip für die #Informationsübertragung genutzt werden.

https://www.golem.de/news/echte-intelligenz-menschliche-neuronen-als-biologischer-computer-verfuegbar-2506-196982.html

SciTech Chronicles. . . . . . . . .Mar 31st, 2025

https://bit.ly/stc033125

#nanostructured #Copper-Tantalum-Lithium #stability #strength #Connectome #cortical #thickness #volume #conductor #Faraday #electrostatic #tube #stromatolites #amino-acids #abiogenesis #carbon-nitrogen #AMSAT-OSCAR #AO-7 #NiCd #AE4JC

SciTech Chronicles. . . . . . . . .Mar 31st, 2025

https://bit.ly/stc033125

#nanostructured #Copper-Tantalum-Lithium #stability #strength #Connectome #cortical #thickness #volume #conductor #Faraday #electrostatic #tube #stromatolites #amino-acids #abiogenesis #carbon-nitrogen #AMSAT-OSCAR #AO-7 #NiCd #AE4JC

SciTech Chronicles. . . . . . . . .Mar 17th, 2025

https://bit.ly/stc031725

#dementia #nitrate #Porphyromonas #Neisseria #Lookup #Registration #IETF #gTLD
#MIMO #FPA #MRA #SQP #wildfires #mesh #Kinéis #Silvanet #cortical #amygdala #neurobiology #ESR1

SciTech Chronicles. . . . . . . . .Mar 17th, 2025

https://bit.ly/stc031725

#dementia #nitrate #Porphyromonas #Neisseria #Lookup #Registration #IETF #gTLD
#MIMO #FPA #MRA #SQP #wildfires #mesh #Kinéis #Silvanet #cortical #amygdala #neurobiology #ESR1

SciTech Chronicles. . . . . . . . .Mar 17th, 2025

https://bit.ly/stc031725

#dementia #nitrate #Porphyromonas #Neisseria #Lookup #Registration #IETF #gTLD
#MIMO #FPA #MRA #SQP #wildfires #mesh #Kinéis #Silvanet #cortical #amygdala #neurobiology #ESR1

New Artist announced for Rewire Festival 2025: 🔥 Cortical 🔥

🎶 Listen to the current LineUp on YouTube and Spotify: https://fyrefestivals.co
🎟️ Get your Tickets now: https://prf.hn/l/EJnYMdO

#Rewire_Festival_2025 #Cortical #fyre_festivals #livemusic #youtube #spotify #music #musicfestivals #playlist #tickets #announcement

The #Izhikevichmodel is a powerful tool for simulating the #spiking and bursting behavior of #neurons with a remarkable balance between biological relevance and computational efficiency 💫 Here is a short introduction along with a #Python implementation to simulate various types of #cortical neurons, including regular spiking, fast spiking, and bursting neurons:

🌍 https://www.fabriziomusacchio.com/blog/2024-04-29-izhikevich_model/

Feel free to share and experiment with it ☺️

#CompNeuro #ComputationalModelling #ComputationalNeuroscience

The #Izhikevichmodel is a powerful tool for simulating the #spiking and bursting behavior of #neurons with a remarkable balance between biological relevance and computational efficiency 💫 Here is a short introduction along with a #Python implementation to simulate various types of #cortical neurons, including regular spiking, fast spiking, and bursting neurons:

🌍 https://www.fabriziomusacchio.com/blog/2024-04-29-izhikevich_model/

Feel free to share and experiment with it ☺️

#CompNeuro #ComputationalModelling #ComputationalNeuroscience

The #Izhikevichmodel is a powerful tool for simulating the #spiking and bursting behavior of #neurons with a remarkable balance between biological relevance and computational efficiency 💫 Here is a short introduction along with a #Python implementation to simulate various types of #cortical neurons, including regular spiking, fast spiking, and bursting neurons:

🌍 https://www.fabriziomusacchio.com/blog/2024-04-29-izhikevich_model/

Feel free to share and experiment with it ☺️

#CompNeuro #ComputationalModelling #ComputationalNeuroscience

The #Izhikevichmodel is a powerful tool for simulating the #spiking and bursting behavior of #neurons with a remarkable balance between biological relevance and computational efficiency 💫 Here is a short introduction along with a #Python implementation to simulate various types of #cortical neurons, including regular spiking, fast spiking, and bursting neurons:

🌍 https://www.fabriziomusacchio.com/blog/2024-04-29-izhikevich_model/

Feel free to share and experiment with it ☺️

#CompNeuro #ComputationalModelling #ComputationalNeuroscience

The #Izhikevichmodel is a powerful tool for simulating the #spiking and bursting behavior of #neurons with a remarkable balance between biological relevance and computational efficiency 💫 Here is a short introduction along with a #Python implementation to simulate various types of #cortical neurons, including regular spiking, fast spiking, and bursting neurons:

🌍 https://www.fabriziomusacchio.com/blog/2024-04-29-izhikevich_model/

Feel free to share and experiment with it ☺️

#CompNeuro #ComputationalModelling #ComputationalNeuroscience

Two-year postdoc position at #NeuroSpin on visual plasticity of blind individuals https://jobrxiv.org/job/unicog-27778-two-year-postdoc-position-at-neurospin-on-visual-plasticity-of-blind-indivi/ "study the #visual #plasticity and potential #cortical #reorganization of #blind individuals"; 3T, 7T #fMRI, 11.7T #MRI

#Cortical reactivations predict future #sensory responses – new work by Nguyen et al. (2023):

🌍 https://www.nature.com/articles/s41586-023-06810-1?error=cookies_not_supported&code=5b78d7ba-20ef-4066-87d3-e4b5926f9f97

#ComNeuro #Neuroscience #Cortex #Memory #MemoryConsolidation

#Cortical reactivations predict future #sensory responses – new work by Nguyen et al. (2023):

🌍 https://www.nature.com/articles/s41586-023-06810-1?error=cookies_not_supported&code=5b78d7ba-20ef-4066-87d3-e4b5926f9f97

#ComNeuro #Neuroscience #Cortex #Memory #MemoryConsolidation

#Cortical reactivations predict future #sensory responses – new work by Nguyen et al. (2023):

🌍 https://www.nature.com/articles/s41586-023-06810-1?error=cookies_not_supported&code=5b78d7ba-20ef-4066-87d3-e4b5926f9f97

#ComNeuro #Neuroscience #Cortex #Memory #MemoryConsolidation

#Cortical reactivations predict future #sensory responses – new work by Nguyen et al. (2023):

🌍 https://www.nature.com/articles/s41586-023-06810-1?error=cookies_not_supported&code=5b78d7ba-20ef-4066-87d3-e4b5926f9f97

#ComNeuro #Neuroscience #Cortex #Memory #MemoryConsolidation