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  1. 🧠 New paper by Pachitariu … @computingnature: spontaneous brainwide activity in mice shows macroscopic coordination that resembles linear dynamics driven by a critically normalized random symmetric matrix.

    #Cortical and brainwide recordings showed power-law variance spectra, slow global activity modes, and little rotational structure, unlike #CA1, which looked closer to an efficient, less correlated code.

    🌍 doi.org/10.1038/s41586-026-105

    #Neuroscience #CompNeuro #NeuralDynamics

  2. 🧠 New paper by Pachitariu … @computingnature: spontaneous brainwide activity in mice shows macroscopic coordination that resembles linear dynamics driven by a critically normalized random symmetric matrix.

    #Cortical and brainwide recordings showed power-law variance spectra, slow global activity modes, and little rotational structure, unlike #CA1, which looked closer to an efficient, less correlated code.

    🌍 doi.org/10.1038/s41586-026-105

    #Neuroscience #CompNeuro #NeuralDynamics

  3. 🧠 New paper by Pachitariu … @computingnature: spontaneous brainwide activity in mice shows macroscopic coordination that resembles linear dynamics driven by a critically normalized random symmetric matrix.

    #Cortical and brainwide recordings showed power-law variance spectra, slow global activity modes, and little rotational structure, unlike #CA1, which looked closer to an efficient, less correlated code.

    🌍 doi.org/10.1038/s41586-026-105

    #Neuroscience #CompNeuro #NeuralDynamics

  4. 🧠 New paper by Pachitariu … @computingnature: spontaneous brainwide activity in mice shows macroscopic coordination that resembles linear dynamics driven by a critically normalized random symmetric matrix.

    #Cortical and brainwide recordings showed power-law variance spectra, slow global activity modes, and little rotational structure, unlike #CA1, which looked closer to an efficient, less correlated code.

    🌍 doi.org/10.1038/s41586-026-105

    #Neuroscience #CompNeuro #NeuralDynamics

  5. 🧠 New paper by Pachitariu … @computingnature: spontaneous brainwide activity in mice shows macroscopic coordination that resembles linear dynamics driven by a critically normalized random symmetric matrix.

    #Cortical and brainwide recordings showed power-law variance spectra, slow global activity modes, and little rotational structure, unlike #CA1, which looked closer to an efficient, less correlated code.

    🌍 doi.org/10.1038/s41586-026-105

    #Neuroscience #CompNeuro #NeuralDynamics

  6. 🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience

  7. 🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience

  8. 🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience

  9. 🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience

  10. 🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons. 🌍 https://doi.org/10.1016/j.neuron.2026.04.017 #Neuroscience

  11. 🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.

    Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.

    🌍 doi.org/10.1016/j.neuron.2026.

    #Neuroscience #CompNeuro

  12. 🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.

    Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.

    🌍 doi.org/10.1016/j.neuron.2026.

    #Neuroscience #CompNeuro

  13. 🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.

    Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.

    🌍 doi.org/10.1016/j.neuron.2026.

    #Neuroscience #CompNeuro

  14. 🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.

    Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.

    🌍 doi.org/10.1016/j.neuron.2026.

    #Neuroscience #CompNeuro

  15. 🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors, they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.

    Mechanistically, tonic #GABA hyperpolarizes #dendrites & deinactivates low-threshold voltage-gated #calcium channels, increasing calcium influx and facilitating calcium-dependent inhibitory #SynapticPlasticity.

    🌍 doi.org/10.1016/j.neuron.2026.

    #Neuroscience #CompNeuro

  16. RE: fediscience.org/@PLOSBiology/1

    🧠 Interesting new work on #cortical #PopulationCoding: Revah, Wolf, Gutnick & Neef show that the #encoding performance of cortical #neurons is not determined by single-cell properties alone, but by a combination of #dendrite size, #synaptic noise statistics, ion channels, and population size.

    🧵1/2

  17. RE: fediscience.org/@PLOSBiology/1

    🧠 Interesting new work on #cortical #PopulationCoding: Revah, Wolf, Gutnick & Neef show that the #encoding performance of cortical #neurons is not determined by single-cell properties alone, but by a combination of #dendrite size, #synaptic noise statistics, ion channels, and population size.

    🧵1/2

  18. RE: fediscience.org/@PLOSBiology/1

    🧠 Interesting new work on #cortical #PopulationCoding: Revah, Wolf, Gutnick & Neef show that the #encoding performance of cortical #neurons is not determined by single-cell properties alone, but by a combination of #dendrite size, #synaptic noise statistics, ion channels, and population size.

    🧵1/2

  19. RE: fediscience.org/@PLOSBiology/1

    🧠 Interesting new work on #cortical #PopulationCoding: Revah, Wolf, Gutnick & Neef show that the #encoding performance of cortical #neurons is not determined by single-cell properties alone, but by a combination of #dendrite size, #synaptic noise statistics, ion channels, and population size.

    🧵1/2

  20. RE: fediscience.org/@PLOSBiology/1

    🧠 Interesting new work on #cortical #PopulationCoding: Revah, Wolf, Gutnick & Neef show that the #encoding performance of cortical #neurons is not determined by single-cell properties alone, but by a combination of #dendrite size, #synaptic noise statistics, ion channels, and population size.

    🧵1/2

  21. 🧠 New preprint by Garcia-Garcia et al.: The authors show that cerebellar #GranuleCells do not simply expand #cortical activity into a high-dimensional code. Instead, they preserve low-dimensional cortical #manifold geometry while reorienting it across contexts. This rotation separates similar tasks, reduces interference, and supports flexible dual-task learning.

    📄 biorxiv.org/content/10.64898/2

    #Neuroscience #NeuralDynamics #CompNeuro

  22. 🧠 New preprint by Garcia-Garcia et al.: The authors show that cerebellar #GranuleCells do not simply expand #cortical activity into a high-dimensional code. Instead, they preserve low-dimensional cortical #manifold geometry while reorienting it across contexts. This rotation separates similar tasks, reduces interference, and supports flexible dual-task learning.

    📄 biorxiv.org/content/10.64898/2

    #Neuroscience #NeuralDynamics #CompNeuro

  23. 🧠 New preprint by Garcia-Garcia et al.: The authors show that cerebellar #GranuleCells do not simply expand #cortical activity into a high-dimensional code. Instead, they preserve low-dimensional cortical #manifold geometry while reorienting it across contexts. This rotation separates similar tasks, reduces interference, and supports flexible dual-task learning.

    📄 biorxiv.org/content/10.64898/2

    #Neuroscience #NeuralDynamics #CompNeuro

  24. 🧠 New preprint by Garcia-Garcia et al.: The authors show that cerebellar #GranuleCells do not simply expand #cortical activity into a high-dimensional code. Instead, they preserve low-dimensional cortical #manifold geometry while reorienting it across contexts. This rotation separates similar tasks, reduces interference, and supports flexible dual-task learning.

    📄 biorxiv.org/content/10.64898/2

    #Neuroscience #NeuralDynamics #CompNeuro

  25. 🧠 New preprint by Garcia-Garcia et al.: The authors show that cerebellar #GranuleCells do not simply expand #cortical activity into a high-dimensional code. Instead, they preserve low-dimensional cortical #manifold geometry while reorienting it across contexts. This rotation separates similar tasks, reduces interference, and supports flexible dual-task learning.

    📄 biorxiv.org/content/10.64898/2

    #Neuroscience #NeuralDynamics #CompNeuro

  26. 「活體」伺服器:科學家培養「迷你人腦」為電腦提供動力

    BBC News 中文 2025-10-08 14:00:00 CST
    科學家正開發以人類神經元「類器官」運算的「生物電腦」。此「濕體」技術目標為發展低功耗 AI 與疾病模型,旨在補充而非取代現有矽基技術,目前尚處早期階段。
    https://www.thenewslens.com/article/259471
    #幹細胞 #生物電腦 #濕體 #人工智慧 #Cortical Labs #類器官 #FinalSpark #科學 #神經元

  27. Cortical development in #primates follows a hierarchical gradient, but how does this vary between species? This study shows that #humans & #macaques share conserved maturation patterns, with humans exhibiting prolonged #cortical development @PLOSBiology plos.io/4prEO65

  28. Cortical development in #primates follows a hierarchical gradient, but how does this vary between species? This study shows that #humans & #macaques share conserved maturation patterns, with humans exhibiting prolonged #cortical development @PLOSBiology plos.io/4prEO65

  29. Cortical development in #primates follows a hierarchical gradient, but how does this vary between species? This study shows that #humans & #macaques share conserved maturation patterns, with humans exhibiting prolonged #cortical development @PLOSBiology plos.io/4prEO65

  30. Cortical development in #primates follows a hierarchical gradient, but how does this vary between species? This study shows that #humans & #macaques share conserved maturation patterns, with humans exhibiting prolonged #cortical development @PLOSBiology plos.io/4prEO65

  31. Cortical development in #primates follows a hierarchical gradient, but how does this vary between species? This study shows that #humans & #macaques share conserved maturation patterns, with humans exhibiting prolonged #cortical development @PLOSBiology plos.io/4prEO65

  32. 🧠 New study by Lempel et al. (2025): Visual experience after eye opening aligns #feedforward inputs (L4) and #RecurrentNetworks (L2/3) in mouse #VisualCortex. This improved alignment, together with enhanced orientation discrimination, creates coherent, reliable sensory codes, revealing how experience shapes stable #cortical representations:

    🌍 doi.org/10.1016/j.neuron.2025.

    #Neuroscience #CompNeuro #Plasticity #CorticalCircuits

  33. 🧠 New study by Lempel et al. (2025): Visual experience after eye opening aligns #feedforward inputs (L4) and #RecurrentNetworks (L2/3) in mouse #VisualCortex. This improved alignment, together with enhanced orientation discrimination, creates coherent, reliable sensory codes, revealing how experience shapes stable #cortical representations:

    🌍 doi.org/10.1016/j.neuron.2025.

    #Neuroscience #CompNeuro #Plasticity #CorticalCircuits

  34. 🧠 New study by Lempel et al. (2025): Visual experience after eye opening aligns #feedforward inputs (L4) and #RecurrentNetworks (L2/3) in mouse #VisualCortex. This improved alignment, together with enhanced orientation discrimination, creates coherent, reliable sensory codes, revealing how experience shapes stable #cortical representations:

    🌍 doi.org/10.1016/j.neuron.2025.

    #Neuroscience #CompNeuro #Plasticity #CorticalCircuits

  35. 🧠 New study by Lempel et al. (2025): Visual experience after eye opening aligns #feedforward inputs (L4) and #RecurrentNetworks (L2/3) in mouse #VisualCortex. This improved alignment, together with enhanced orientation discrimination, creates coherent, reliable sensory codes, revealing how experience shapes stable #cortical representations:

    🌍 doi.org/10.1016/j.neuron.2025.

    #Neuroscience #CompNeuro #Plasticity #CorticalCircuits

  36. 🧠 New study by Lempel et al. (2025): Visual experience after eye opening aligns #feedforward inputs (L4) and #RecurrentNetworks (L2/3) in mouse #VisualCortex. This improved alignment, together with enhanced orientation discrimination, creates coherent, reliable sensory codes, revealing how experience shapes stable #cortical representations:

    🌍 doi.org/10.1016/j.neuron.2025.

    #Neuroscience #CompNeuro #Plasticity #CorticalCircuits

  37. 📚 New preprint by Song et al.: Geometry of #NeuralDynamics along the #cortical #attractor landscape reflects changes in attention. They show that while attractor positions are determined by cortical organization, the geometry of neural dynamics on the landscape changes systematically with attentional states and contexts.

    🌍 biorxiv.org/content/10.1101/20

    #Neuroscience #Attention #fMRI #CompNeuro