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#innateimmune — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #innateimmune, aggregated by home.social.

  1. How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of three families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM

  2. How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of three families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM

  3. How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of three families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM

  4. How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of three families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM

  5. How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of three families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM

  6. The #GPCR CMKLR1 responds to the #adipokine #chemerin and is abundant in #InnateImmune cells. Structure of CMKLR1 in complex with #Gprotein and a peptide agonist (+ mutagenesis & simulations) reveals mechanisms of action #PLOSBiology plos.io/4a6Igvd

  7. The #GPCR CMKLR1 responds to the #adipokine #chemerin and is abundant in #InnateImmune cells. Structure of CMKLR1 in complex with #Gprotein and a peptide agonist (+ mutagenesis & simulations) reveals mechanisms of action #PLOSBiology plos.io/4a6Igvd

  8. The #GPCR CMKLR1 responds to the #adipokine #chemerin and is abundant in #InnateImmune cells. Structure of CMKLR1 in complex with #Gprotein and a peptide agonist (+ mutagenesis & simulations) reveals mechanisms of action #PLOSBiology plos.io/4a6Igvd

  9. The #GPCR CMKLR1 responds to the #adipokine #chemerin and is abundant in #InnateImmune cells. Structure of CMKLR1 in complex with #Gprotein and a peptide agonist (+ mutagenesis & simulations) reveals mechanisms of action #PLOSBiology plos.io/4a6Igvd

  10. Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry

    embopress.org/doi/full/10.1525

  11. Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry

    embopress.org/doi/full/10.1525

  12. Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry

    embopress.org/doi/full/10.1525

  13. MICa/b-dependent activation of natural killer cells by CD64+ inflammatory type 2 dendritic cells contributes to #autoimmunity

    Pathology of primary Sjögren's syndrome is known to involve #interferons, but Enrique Martin-Gayo et al @UAM_Medicina show additional roles also for #innateimmune cells like natural killer and #dendritic cells

    embopress.org/doi/full/10.1525

  14. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  15. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  16. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ