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#innateimmune — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #innateimmune, aggregated by home.social.

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  1. Innate immune signaling and #cancer: This study shows that the tissue-protective functions of Toll-mediated #InnateImmune signaling can be misused by premalignant cells in #Drosophila to induce overgrowth in early stages of #tumor development @PLOSBiology plos.io/4jqpmUh

  2. Innate immune signaling and #cancer: This study shows that the tissue-protective functions of Toll-mediated #InnateImmune signaling can be misused by premalignant cells in #Drosophila to induce overgrowth in early stages of #tumor development @PLOSBiology plos.io/4jqpmUh

  3. Innate immune signaling and #cancer: This study shows that the tissue-protective functions of Toll-mediated #InnateImmune signaling can be misused by premalignant cells in #Drosophila to induce overgrowth in early stages of #tumor development @PLOSBiology plos.io/4jqpmUh

  4. Innate immune signaling and #cancer: This study shows that the tissue-protective functions of Toll-mediated #InnateImmune signaling can be misused by premalignant cells in #Drosophila to induce overgrowth in early stages of #tumor development @PLOSBiology plos.io/4jqpmUh

  5. Innate immune signaling and #cancer: This study shows that the tissue-protective functions of Toll-mediated #InnateImmune signaling can be misused by premalignant cells in #Drosophila to induce overgrowth in early stages of #tumor development @PLOSBiology plos.io/4jqpmUh

  6. #ProteinQC pathways play key roles in resistance to #pathogens. @manishgrover_4 @barkoulab &co show that #proteasome regulation keeps #InnateImmune responses against natural pathogens of #Celegans in check in a tissue-specific manner #PLOSBiology plos.io/3PhIjLW

  7. #ProteinQC pathways play key roles in resistance to #pathogens. @manishgrover_4 @barkoulab &co show that #proteasome regulation keeps #InnateImmune responses against natural pathogens of #Celegans in check in a tissue-specific manner #PLOSBiology plos.io/3PhIjLW

  8. #ProteinQC pathways play key roles in resistance to #pathogens. @manishgrover_4 @barkoulab &co show that #proteasome regulation keeps #InnateImmune responses against natural pathogens of #Celegans in check in a tissue-specific manner #PLOSBiology plos.io/3PhIjLW

  9. #ProteinQC pathways play key roles in resistance to #pathogens. @manishgrover_4 @barkoulab &co show that #proteasome regulation keeps #InnateImmune responses against natural pathogens of #Celegans in check in a tissue-specific manner #PLOSBiology plos.io/3PhIjLW

  10. #ProteinQC pathways play key roles in resistance to #pathogens. @manishgrover_4 @barkoulab &co show that #proteasome regulation keeps #InnateImmune responses against natural pathogens of #Celegans in check in a tissue-specific manner #PLOSBiology plos.io/3PhIjLW

  11. How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of three families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM

  12. How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of three families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM

  13. How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of three families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM

  14. How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of three families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM

  15. How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of three families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM

  16. The #GPCR CMKLR1 responds to the #adipokine #chemerin and is abundant in #InnateImmune cells. Structure of CMKLR1 in complex with #Gprotein and a peptide agonist (+ mutagenesis & simulations) reveals mechanisms of action #PLOSBiology plos.io/4a6Igvd

  17. The #GPCR CMKLR1 responds to the #adipokine #chemerin and is abundant in #InnateImmune cells. Structure of CMKLR1 in complex with #Gprotein and a peptide agonist (+ mutagenesis & simulations) reveals mechanisms of action #PLOSBiology plos.io/4a6Igvd

  18. The #GPCR CMKLR1 responds to the #adipokine #chemerin and is abundant in #InnateImmune cells. Structure of CMKLR1 in complex with #Gprotein and a peptide agonist (+ mutagenesis & simulations) reveals mechanisms of action #PLOSBiology plos.io/4a6Igvd

  19. The #GPCR CMKLR1 responds to the #adipokine #chemerin and is abundant in #InnateImmune cells. Structure of CMKLR1 in complex with #Gprotein and a peptide agonist (+ mutagenesis & simulations) reveals mechanisms of action #PLOSBiology plos.io/4a6Igvd

  20. The #GPCR CMKLR1 responds to the #adipokine #chemerin and is abundant in #InnateImmune cells. Structure of CMKLR1 in complex with #Gprotein and a peptide agonist (+ mutagenesis & simulations) reveals mechanisms of action #PLOSBiology plos.io/4a6Igvd

  21. Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry

    embopress.org/doi/full/10.1525

  22. Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry

    embopress.org/doi/full/10.1525

  23. Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry

    embopress.org/doi/full/10.1525

  24. Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry

    embopress.org/doi/full/10.1525

  25. Seung Kim, Frederick Dick et al show that resting #Bcells are uniquely sensitive to #EZH2 #polycomb complex inhibition, which activates expression of repetitive genomic elements and subsequent #innateimmune receptor signaling in a form of viral mimicry

    embopress.org/doi/full/10.1525

  26. MICa/b-dependent activation of natural killer cells by CD64+ inflammatory type 2 dendritic cells contributes to #autoimmunity

    Pathology of primary Sjögren's syndrome is known to involve #interferons, but Enrique Martin-Gayo et al @UAM_Medicina show additional roles also for #innateimmune cells like natural killer and #dendritic cells

    embopress.org/doi/full/10.1525

  27. MICa/b-dependent activation of natural killer cells by CD64+ inflammatory type 2 dendritic cells contributes to #autoimmunity

    Pathology of primary Sjögren's syndrome is known to involve #interferons, but Enrique Martin-Gayo et al @UAM_Medicina show additional roles also for #innateimmune cells like natural killer and #dendritic cells

    embopress.org/doi/full/10.1525

  28. MICa/b-dependent activation of natural killer cells by CD64+ inflammatory type 2 dendritic cells contributes to #autoimmunity

    Pathology of primary Sjögren's syndrome is known to involve #interferons, but Enrique Martin-Gayo et al @UAM_Medicina show additional roles also for #innateimmune cells like natural killer and #dendritic cells

    embopress.org/doi/full/10.1525

  29. MICa/b-dependent activation of natural killer cells by CD64+ inflammatory type 2 dendritic cells contributes to #autoimmunity

    Pathology of primary Sjögren's syndrome is known to involve #interferons, but Enrique Martin-Gayo et al @UAM_Medicina show additional roles also for #innateimmune cells like natural killer and #dendritic cells

    embopress.org/doi/full/10.1525

  30. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  31. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  32. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  33. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  34. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  35. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  36. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  37. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  38. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  39. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  40. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  41. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  42. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  43. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ

  44. The past 20 years have revealed several new #InnateImmune sensing & #CellDeath pathways with disease relevance. @RebeccaTweedell @KannegantiLab look back at the impact of these discoveries & forwards toward their future therapeutic potential #PLOSBiology plos.io/40O9xxQ