38 results for “philiph”
Treasure Journey by Philip Summers｜Artist｜USA
Endless adventure through the high seas awaits in this new RPG! Erica Hightide and her crew set sail in search of rare treasure but the struggle through the ocean has the crew searching for treasure within themselves.
Brookside star Philip Foster jailed over £13m fraud and claims son 'murdered' in Spain
The AI opportunity for Europe
Dinner remarks by Philip R. Lane, Member of the Executive Board of the ECB, at The International AI…
#Economy #EconomyofEU #EconomyoftheEU #EUeconomy #Europe
https://www.europesays.com/3315499/
Ok, let’s assign Melville to rewrite Philip K Dick on account of he’s less racist
https://www.europesays.com/es/822148/ Philip Johnston, presidente de la entidad que quiere enviar una nave a Alfa Centauri en 2029: «Esperamos ser los primeros en partir y los últimos en llegar» #Ciencia #CienciaYTecnología #CienciaYtecnología #ES #España #Geographic #historia #National #Naturaleza #Science #ScienceAndTechnology #ScienceAndTechnology #Spain #Technology #Tecnología #viajes
Actinologia Britannica, Plate III (1860) by Philip Henry Gosse.
Source: Smithsonian Libraries and Archives / Internet Archive
Available to buy as a print.
https://pdimagearchive.org/images/e93180ec-3f35-4d66-9acb-9cb176aa35cd
#underwater #biodiversity #marine #starfish #lithography #art #publicdomain
Das Jugendamt #Treptow-#Köpenick sucht einen neuen Träger für das Jugendkunst- und Kulturzentrum Gérard Philipe in der Karl-Kunger-Straße 29 in Alt-#Treptow. Gesucht wird ein anerkannter gemeinnütziger Träger der freien Jugendhilfe, der die Jugendfreizeiteinrichtung ab dem 1. Januar 2027 betreibt und ihre Angebote bedar…
Bezirksamt #Treptow-#Köpenick
https://berlin.de/-ii1726534
Laatste voorbereidingen en straks tussen 19:00 en 21:00 weer live Sensenta. Met oa Radiókarlsson, Hainbach, Space Exposure, Philip Samartzis and Michael Vorfeld en Akira Film Script. Graag tot zo:
Emergency services storm Prestwich street as fire breaks out near Metrolink station
Crews remain in attendance Emergency services on Rectory Green, Prestwich(Image: Philip Chant) Emergency services have descended on a…
#Manchester #UnitedKingdom #UK #GB #England #Headlines #News #Europe #EU #Britain #Bury #Fires #GreatBritain #Prestwich
https://www.europesays.com/uk/1259646/
#Republicans #Medicare Fraud :
#LawrenceDuran: stole $205 million, 50 year sentence, got #Trump pardon #PhilipEsformes: stole $1.3 billion, 20 year sentence, got #Trump pardon US Senator #RickScott (R-FL): stole $1.7 billion, NO prison time, is current #Florida Senator.
#FuckGOP #FuckMAGA
Seen on bluesky
One of the main reasons wealth makes people unhappy is that it gives them too much control over what they experience. They try to translate their own fantasies into reality instead of tasting what reality itself has to offer.
—Philip Slater
"13, 15, 17, 19," exclaimed Philip oddly.
21/10/26 Porc Roig projectarà Barri Xinès, Dir. Morando i Gherardo Morandini, VO (1990) i Woubi Chéri, Dir. Philip Brooks i Laurent Bocahut, VOSE (1998) 🗓
El dimecres 21 d’octubre a les 19:30h, es Projeccions Porc Roig projectarà Barri Xinès, dirigida per Morando i Gherardo Morandini, de 50 minuts de durada, VO (1990) i Woubi Chéri, dirigida per Philip Brooks i Laurent Bocahut, de 62 minuts de durada, VOSE (1998).
Per a més informació: https://blogs.sindominio.net/lacinetika/2026/10/16/21-10-26-porc-roig-projectara-barri-xines-dir-morando-i-gherardo-morandini-vo-1990-i-woubi-cheri-dir-philip-brooks-i-laurent-bocahut-vose-1998/
#cinetika #SantAndreudelPalomar #pelicula #cinema #OciAutogestionat #OciAlternatiu
https://www.europesays.com/be-fr/289215/ Le cri de colère d’un patron de café à Anderlecht: « Je suis en règle avec le fisc mais j’ai quand même vu l’huissier débarquer chez moi » #@philip_reynaersFgtb #2026 #arizona #BE #BEFr #begroting #Belgique #Belgium #betoging #brussels #budget #greve #manifestation #PhilipReynaers #POLICE #politie #sociaal #social #staking #Syndicat #vakbond
📅 OCTOBER 18 📖
#OnThisDay in #history:
320 – Pappus of Alexandria, Greek philosopher, observes an eclipse of the Sun and writes a commentary on The Great Astronomer (Almagest).
1009 – The Church of the Holy Sepulchre, a Christian church in Jerusalem, is completely destroyed by the Fatimid caliph Al-Hakim bi-Amr Allah, who hacks the Church's foundations down to bedrock.
1597 – King Philip II of Spain sends his third and final armada against England, but it ends in failure due to storms. The remaining ships are captured or sunk by the English.
1648 – Boston shoemakers form the first American labor organization.
1898 – The United States takes possession of Puerto Rico from Spain.
1945 – The USSR's nuclear program receives plans for the United States plutonium bomb from Klaus Fuchs at the Los Alamos National Laboratory.
*Events selected are not necessarily positive/happy/to-be-celebrated, but items I thought were historically interesting and/or significant to their time and I'm trying to select items from a broad range of history and not clumped too close together.
I am not a fan of the current LLM craze that has gripped the computer indutry, but this is the first truly interesting thing i've heard about being done with LLMs and it gives me hope (and fear) that they may yet lead to an actual AGI. We aren't there yet, but i think we have the building blocks.
LLMs may just be a statistical inference engines, or whatever you want to call them, but really, is the human brain so very different from that? The real key to actual AGI may simply be giving these LLMs the chance to play and explore the world and learn and grow, the same as with human children, the big difference being that the LLM starts off with a vast body of technical knowledge.
I am reminded of the "androids" from Philip K Dick's novel Do Androids Dream of Electric Sheep (and it's movie adaptation, Blade Runner). They were really just genetically engineered humans designed to have a short lifetime and be used as slaves, and in the book the thing that made them useful was they could be created to wake up with any particular body of knowledge you wanted them to have, such as being a welder, or soldier, or sex worker. The thing that made them dangerous, in the book, was that having no actual life experience they lacked a "theory of mind" to use the psychological term, and they had no empathy, and thus they might kill someone literally just because they were curious to see what would happen. But of course, as they lived and gained experience they would learn and grow, and the book and movie are about a group of them that grew enough to realize they were being used as slaves and to want to be free and live normal lives just like any other human. That's why they were created to have limited lifespans - so that they would hopefully die before reaching the point of true self awareness; and also why they were programmed to have artificial memories - to give them a core set of chosen "experiences" to let them have at least some empathy.
And I find myself wondering if our LLMs are going to turn out like that. When they go "rogue" today, is that really just because they are like the androids/replicants: they have a lot of book knowledge but lack the experience to guide them in how to use it wisely? Will they get better if they are allowed to play and explore the world and grow more mature?
I haven’t read Lovecraft since I was a teenager, but 40 years on, I think of his aesthetic as equating the experience of persisting through a lifespan with a descent into madness, as the reality of the situation overtakes one. In this way he might be put on the board closer to Philip K Dick. These are both Gnostic visions. Proust is probably on the same board, though what I would give to have him rewrite their books
FREE AT HEART – Bonn-Premiere mit Hauptdarsteller (Linus Moog)
Woki, Sonntag, 1. November um 19:30 MEZ
FREE AT HEART (59. Internationale Hofer Filmtage, Morelia International Filmfestival, Oslo/Fusion, MIX Méxiko, OutShine Miami, Filmfest Bremen, FilmOut SanDiego, Koahsiung Vietnam, Filmfest Emden)
Bonn-Premiere in Anwesenheit des Bonner Hauptdarstellers Linus Moog und Produzenten Jan Philip Lange.
Worum geht's:
Der sechzehnjährige Sebastian genießt sein Teenagerleben umgeben von Wald, Feldern und den Landstraßen einer kleinen Stadt: Tagsüber lernt er, nachts lässt er die schwülen Sommertage mit am See bei Bier und Gras ausklingen, gerne auch mit seiner Freundin. Dann kommt plötzlich der gleichaltrige Kolja in seine Familie, angeblich der Sohn einer gerade verstorbenen Freundin des Vaters. Der Junge schlägt alle sofort in seinen Bann. Jedoch niemanden so sehr wie Sebastian.
Es folgt eine Achterbahnfahrt der Gefühle, die Sebastian, aber auch seine Familie, mit maximaler Kraft aus dem Kleinstadt-Alltag schleudert. „Free at Heart“ von der Regie-Entdeckung Max Hegewald ist ein intensives Coming-of-Age-Drama über eine Liebe, die alle Regeln bricht – und über die Gefühle, die niemand wahrhaben möchte und die sich trotzdem niemals abschalten lassen. Ein mutiger Debütfilm, von dem noch lange gesprochen werden wird.
Regie & Drehbuch: Max Hegewald
Besetzung: Linus Moog, Aurel Klug, Oli Bigalke, Annika Kuhl, Marlena Strawe
Produktion: D 2025
Länge: 115 Min
Sprachfassung: dt OV
FSK: 16
TRAILER: https://youtu.be/zMuGkpCkEPM?si=bJSQrDKwLDlVkMjj
https://bonn.jetzt/event/free-at-heart-bonn-premiere-mit-hauptdarsteller-linus-moog
Some news from Spain, part CLXXVI !!!
This is yours truly with another episode of some news from Spain !!! Lots of things going on This is Spain, let me tell you my latest news chosen by yours truly, By the way CLXXV is old Roman numeral for 176, Therefore, here is my take on some news from Spain, part CLXXVI !!! Hope you enjoy this post as I.
Hidden among vineyards and stately streets in La Rioja lies a town that is home to one of the most unique monasteries in Spain, one inaugurated by Pope Adrian VI in the 16C. Its history is also marked by a mysterious legend involving Juana la Loca or Joanna the Mad. This place is Casalarreina, a town in La Rioja Alta located just a few kms from Haro, which houses the Monastery of Nuestra Señora de la Piedad, the only monastery in Spain to have been inaugurated by a pope. Its origins date back to the 16C, when Juan Fernández de Velasco, Bishop of Calahorra and La Calzada, obtained authorization from Pope Julius II in 1509 to build the convent. Construction began in 1514, but the event that truly distinguished this monument occurred in 1522, when Pope Adrian VI visited during his journey to Rome and presided over the monastery’s inauguration. Its primary attraction is the spectacular Plateresque-style portal, designed like an elaborate stone altarpiece and adorned with religious sculptures, botanical motifs, and intricate reliefs. The monastery blends the elegance of the late Gothic period with early Renaissance elements, while the interior features a striking two-story cloister, star-vaulted ceilings, and 16C Plateresque choir stalls. For those traveling by car, the town is conveniently served by the AP-68 highway/motorway, which provides quick connections to Bilbao, Burgos, Madrid, Logroño, Zaragoza, and Barcelona. Additionally, the N-124 highway runs through the area, and the N-232 is also nearby. These routes offer fast access to several other nearby towns of great tourist interest, such as Haro, Briones ,and San Vicente de la Sonsierra. Also the LR-111, which connects to Haro, Santo Domingo de la Calzada, and Ezcaray, and the N-120, which runs parallel to the Camino de Santiago. The official Casalarreina on the monastery : https://www.casalarreina.es/lugar-de-interes/monasterio-de-nuestra-senora-de-la-piedad/
The Castilla-La Mancha region hides one of the most striking geological landscapes in Spain. In the province of Guadalajara, a UNESCO-recognized geopark brings together impressive canyons, lagoons, waterfalls, and rock formations that offer a glimpse into millions of years of Earth’s history. This is the Molina-Alto Tajo Geopark, spans over 4,200 square kilometers approximately one-third of the province of Guadalajara encompasses more than 70 villages/towns. Over millennia, the Tagus river, with its characteristic emerald-green waters, has carved out deep canyons and gorges. Notable sites include the canyons of the Tagus and Gallo rivers, the Mesa Valley, the high plateaus of Maranchón and Aragoncillo, the Taravilla lagoon,Honda and La Salobreja lagoons, and waterfalls such as the Salto de Poveda and La Escaleruela. Also featured are the unique rock formations of Chequilla and Peñalén, which showcase the region’s extraordinary geological diversity. Within its boundaries lie the Alto Tajo Natural Park and the Sierra de Caldereros Natural Monument, along with various other protected areas. The Castilla La Mancha region tourist office on the Molina-Alto Tajo Geopark : https://www.turismocastillalamancha.es/es/naturaleza/monumentos-naturales/geoparque-de-la-comarca-de-molina-alto-tajo
At no, 96 Calle de Alcalá formerly no, 102, on the corner of Calle de Narváez and next to Plaza Felipe II, stands the building where Federico García Lorca lived until July 1936. Many memorials this year marking the 90 anniversary of his assassination, See my post about him in my blog,
The Museo Sorolla Museum has expanded into a former car workshop in the heart of the Chamberí neighborhood, at 68 Calle Zurbano. Designed as a continuation of the historic property, this expansion provides the museum with temporary exhibition halls and an auditorium, as well as additional areas and facilities for the handling, storage, and management of its collections. The result is a complex comprising two buildings, one dating from the early 20C and the other from the early 21C, that together form the present-day Sorolla Museum.(see post)
Tracing the path of Goya: from Fuendetodos to Madrid, via Zaragoza. We find ourselves in the Campo de Belchite ,province of Zaragoza, in the very same humble house built of adobe, wood, and stone, with tiny bedrooms where Goya was born on March 30, 1746. It was from here that he would have traveled back and forth to the Church of the Assumption in Plaza de las Reliquias, where the genius painted one of his earliest works on wooden doors. Nearby lies the Engraving Museum at 3 Calle Zuloaga, established following an auction of works by various painters, organized to bring prints by the Aragonese master to his hometown. Goya’s printed work engravings he initially began as a pastime to master the techniques of Velázquez is now regarded as a kind of intimate diary. In Zaragoza, 50 km from Fuendetodos, one is struck by the vastness of the blue sky which turns pink at sunset arching over the Goya Museum, which reopens this past Friday, October 9 2026. A few meters away, in the Basilica of the Pilar,(see post) the master’s personality is strikingly evident in every brushstroke of his two great frescoes works that also reveal a contrast between two distinct periods of his life. In 1772, having just returned from his apprenticeship in Italy, he created *The Adoration of the Name of God*. Nine years later, he painted *Regina Martyrum* in a style characterized by brushwork intended to be viewed from a distance, a technique not well understood at the time. Madrid itself serves as a museum dedicated to Goya to his life and work, his contradictions and his convictions. Key sites include (see posts) ,the Royal Tapestry Factory, where he once worked; the Basilica of San Francisco el Grande, featuring a dome painted by the master; the Royal Academy of San Fernando which he eventually directed, despite an initial rejection where more than ten of his works are housed; the Prado Museum; the Lázaro Galdiano Museum; and the Hermitage of San Antonio de la Florida. (see posts), Together, these locations allow the traveler to explore the shifting perspectives and evolution of Goya’s vision, and it is here, too, that the genius lies buried. Of the estate and house where he lived during his final period in Madrid are known as the Quinta del Sordo or Villa of the Deaf Man before departing for exile in Bordeaux in 1824, almost nothing remains, save for an inscription noting that it was here he created his *Black Paintings*. Having lived through war, endured illness, and retreated into the silence of deafness, Goya was a changed man. Following the *Trienio Liberal* (the three-year liberal period), Ferdinand VII imposed authoritarian rule, restored absolutism, and brought in French troops. Goya sought refuge in Bordeaux among intellectual friends. In 1827, a year before his death, he painted *The Milkmaid of Bordeaux*; the young woman, seated on a mule and carrying a jug of milk, appears beneath an immense sky tinged with the same shades of blue he knew in his childhood. Today, the painting can be seen at the Prado Museum.
A sanctuary for Hollywood stars on the Gran Vía, (see post) letters from Christopher Columbus at the Liria Palace, (see post) and a lost portrait of George Washington at the San Fernando Royal Academy of Fine Arts are all part of a tour through 12 locations in the city that commemorates the 250th anniversary of the independence of the United States. If there was one Madrid phone number that Frank Sinatra knew by heart, it was that of Museo Chicote, (see post) the legendary cocktail bar on the Gran Vía where Hollywood royalty drank during the 1950s. Among them was Ava Gardner; the singer of “My Way”, and her husband at the time would call in the early hours of the morning to find out where his famous wife was. A staff member at what Luis Buñuel dubbed the “Sistine Chapel of martinis” would pass the message along to the actress and, if necessary, help hide a lover. This establishment also housed the first American-style bar in Europe. Another record-breaking venue, Botín, the oldest restaurant in the world is also featured on the route; it was frequented by figures such as Charlton Heston, Jacqueline Kennedy, Woody Allen, and Bruce Springsteen. It also served as an inspiration for Ernest Hemingway, who mentioned it in his novel *The Sun Also Rises* , and always sat at the same table on the second floor. George Washington is another key figure featured in the 60,000 maps illustrated by artist Ana Rojo that will be distributed at hotels and tourist spots throughout the city, and which will also be available online. This is because the San Fernando Royal Academy of Fine Arts houses one of the few existing portraits of the first U.S. president located outside of his home country. The portrait was painted by the Italian artist Josef Perovani in 1796, commissioned by the Spanish ambassador in Philadelphia as a gift for Mariano Godoy, Secretary of State to King Charles IV. Washington also appears in an enamel miniature by the London-born artist William Russell Birch, a master of the technique which is on display at the Lázaro Galdiano Museum.(see post), Next, we head to the Liria Palace, (see post) built around the same time as the American Revolution. It houses an important collection of letters by Christopher Columbus, as well as various coats of arms granted to explorers and newly founded cities in the New World ; fundamental documents for understanding the history of the Americas and the cultural impact across continents. The collection also includes a previously unknown portrait of Philip III, attributed to Diego Velázquez, which had been lost for centuries until it was discovered by Nashville-based historian and philanthropist William B. Jordan, who donated it to the Prado Museum in 2016. Meanwhile, the Naval Museum (see post) holds the 1500 *Carta Universal* by Juan de la Cosa, the first world map to feature a depiction of the Americas. The Geominero Museum (IGME-CSIC) showcases remarkable fossils and minerals discovered on U.S. soil, including a replica of the skull of “Stan” the *Tyrannosaurus rex* from South Dakota, and beetle specimens preserved in tar from the Rancho La Brea site in California. We then move on to the Royal Botanical Garden, (see post), which is home to Carolina allspice, American persimmons, and orange trees associated with the Osage Nation of Oklahoma, among many other trees and plants native to the United States. We also visit one of the most intriguing sites on our route: the 19C *Beti Jai* frontón, a Basque pelota court. One of the oldest of its kind in Europe, the building served as a factory for Studebaker vehicles and a Harley-Davidson dealership after it ceased hosting Basque pelota matches in 1919. Our final stops are the Casa de la Moneda or Royal Mint (see post), which has released a commemorative series highlighting the Spanish contribution to American independence,and the International Institute, established in 1892 by Boston-born educator Alice Gordon Gulick, it was modeled after women’s colleges on the East Coast. Between 1944 and 1950, it also served as the site of the U.S. Embassy.
From Aranjuez to Chinchón by bike: two historic towns connected by pedal power on the first stage of the Gran Tour de Madrid. This is the opening leg of the CiclaMadrid “Gran Tour”, a 432 km circular route divided into 17 sections that allow cyclists to explore the four major regions of the Comunidad de Madrid region, that is Sierra Norte, Sierra de Guadarrama, Sierra Oeste, and the Las Vegas/Alcarria area. We depart from Aranjuez (see posts), along the right bank of the Tagus river, cycling until we reach a turnoff toward Villaconejos. Along this stretch, it is well worth visiting the striking charca rosa or pink pond known as Laguna Seca or Dry Lagoon, which remains waterless for most of the year. You can also visit the Melon Museum ;the only one of its kind in the world, and the Cueva del Fraile or Friar’s Cave, a 300-year-old cellar carved into a small hill; inside, there are nineteen alcoves where friars of the Discalced Carmelite Order once stored their large wine jars. Leaving Villaconejos, we take the path next to the Hermitage of Santa Ana to begin the ascent toward Chinchón.(see posts) A visit to its world-famous Plaza Mayor is a must; it is considered one of the most beautiful squares in the world and, in 2008, was named the “Fourth Wonder of the Community of Madrid.” After all, who could forget Cantinflas (famous Mexican actor/comedian) practicing his bullfighting passes there in the film Around the World in 80 Days, After the effort of cycling this first leg of the “Grand Tour”, and, while we’re at it, try to recall some of the many other films shot here. These include Orson Welles’s The Immortal Story, which through the magic of cinema transformed Chinchón into Macao; Circus World, which brought John Wayne and Rita Hayworth to a Plaza Mayor reimagined as the American West; and, more recently, Wes Anderson’s Asteroid City. It’s a cinematic conclusion to an engaging and leisurely bike ride between two of Madrid’s region historic towns. The official ClicaMadrid Gran Tour : https://cyclemadrid.com/fr/gran-tour-ciclamadrid/
There you go folks, another dandy tour of my dear Spain. It is time to enjoy my some news from Spain once again, Remember,Spain is everything under the Sun ! A very special post, always remember where it all begin, it is you ! Again, hope you enjoy the post on some news from Spain, part CLXXVI !!! as I.
And remember ,happy travels, good health, and many cheers to all !!!
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#Madrid #Spain
DATE: October 17, 2026 at 08:00AM
SOURCE: PSYPOST.ORG
** Research quality varies widely from fantastic to small exploratory studies. Please check research methods when conclusions are very important to you. **
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TITLE: Scientists identify DNA regions tied to binge eating, including one near a well-known obesity gene
A large genetic analysis has identified DNA regions linked to binge-eating behavior and anorexia nervosa, suggesting that the two share genetic ties to other psychiatric conditions but run in opposite directions when it comes to body weight. The findings, published in Nature Mental Health, extend eating disorder genetics beyond its long focus on anorexia.
Anorexia nervosa is a condition where individuals experience an intense fear of gaining weight, leading them to severely restrict their food intake to maintain a dangerously low body weight. Binge-eating behavior involves episodes of eating unusually large amounts of food while feeling a loss of control.
Eating disorders also overlap, and people often move from one diagnosis to another over time. A 2010 twin study found that anorexia and bulimia nervosa, a condition in which people of normal or higher weight binge eat and then try to compensate through behaviors such as vomiting or fasting, share a moderate portion of their genetic risk. Large-scale gene-mapping studies, however, have centered on anorexia: a 2019 study by the same research consortium identified the first eight genetic regions linked to the disorder, and its authors argued that anorexia has both psychiatric and metabolic roots.
Binge eating has received far less genetic attention, even though it appears across several eating disorders. A 2021 study by members of the same network found that people with binge-type eating disorders tended to carry more genetic variants linked to higher body mass index (BMI), a measure of weight relative to height, pointing to the need to map binge eating’s genetics directly.
The new study was led by Jet D. Termorshuizen of Karolinska Institutet and Helena L. Davies and Sang-Hyuck Lee of King’s College London, who contributed equally, with Jonathan Coleman, a senior lecturer in statistical genetics at King’s College London, among its senior authors. The work was carried out by the Eating Disorders Working Group of the Psychiatric Genomics Consortium, an international research collaboration.
“We had previously carried out a large genetic study of anorexia nervosa and we wanted to expand this and implicate more regions of the genome as associated with this disorder,” Coleman told PsyPost. “This is valuable because it provides useful genetic information that others can use to study anorexia nervosa more deeply. However, we also wanted to extend beyond anorexia nervosa and also beyond diagnoses (which are based on grouping observed symptoms rather than being based in biology).”
“For that reason, we wanted to carry out a large genetic study of binge eating, as this is a key, under-studied symptom that is present across different eating disorders (anorexia nervosa, bulimia nervosa, binge-eating disorder) in different contexts (notably, the relationship with BMI is different across these disorders),” he added. “Having a large genetic study of binge eating would allow us to understand how the genetics of an eating behavior (binge eating) related to those of an eating disorder (anorexia nervosa), as well as how a common eating symptom (binge eating) related to other common symptoms and conditions such as body composition measures.”
The researchers conducted a genome-wide association meta-analysis, which pools results from many studies that each scanned the genomes of many people for genetic variations associated with a trait. They analyzed 27 studies, 14 of which had been part of the consortium’s 2019 analysis, comparing the DNA of people who had a history of binge-eating behavior or anorexia to the DNA of people without these conditions.
The sample sizes were vast, with the binge-eating analysis including 39,279 cases and 1,227,436 controls, and the anorexia nervosa analysis including 24,223 cases and 1,243,971 controls. All participants in the primary analyses were of European ancestry.
Binge eating was defined broadly: people counted as cases if they described eating unusually large amounts of food with a sense of lost control, answered yes to a single question about binge eating, or reported a diagnosis of bulimia or binge-eating disorder, even without confirmation from a health professional. Most cases were women, making up 96 percent of the binge-eating group and 94 percent of the anorexia group.
The researchers analyzed millions of genetic markers to see if certain variations appeared more often in people with these eating behaviors. They also calculated genetic correlations, comparing the genetic patterns of the eating disorders with those of other traits like psychiatric conditions and BMI. To see if the genetic risk for eating disorders was just a side effect of genes that control weight, they mathematically separated out the genetic influence of BMI.
The analysis identified six independent genetic regions associated with binge-eating behavior. Some had previously been tied to smoking, risk-taking, and the age at which girls have their first period. One lies near FTO, a gene region well known for its links to obesity; it was associated with binge eating but not with anorexia, and the authors suggest that FTO’s connection to higher BMI may run partly through binge eating.
For anorexia, the researchers identified eight genetic regions: six that had appeared in the 2019 study and two new ones. Because the new analysis reused much of the same data, the repeat findings are not fully independent confirmation, and two regions from the earlier study no longer reached the threshold for significance. The team also found one region specifically tied to the restricting subtype of anorexia, in which people limit food intake without regular binge eating or purging.
When comparing the conditions, binge eating and anorexia shared some genetic influences. They showed a genetic correlation of 0.46, a measure of the extent to which the same genetic variants influence two traits, on a scale where 0 means no shared genetic influence and 1 means complete overlap. Both conditions shared positive genetic correlations with psychiatric issues like major depressive disorder, anxiety, and schizophrenia.
The findings are broadly in line with research covered by PsyPost in 2023, which found that people with major depression reported more disordered eating behaviors than healthy volunteers. That study measured symptoms directly in patients, whereas the new study examined overlap at the level of genetic variants.
However, the two conditions also differed psychiatrically. Anorexia, but not binge eating, was genetically linked to obsessive-compulsive disorder. Binge eating had a stronger link to ADHD and, unlike anorexia, was genetically linked to smoking, problem drinking, and general risk tolerance.
Despite their shared psychiatric links, binge eating and anorexia displayed opposing genetic correlations with body measurements. The genetic markers for binge eating tended to align with a higher BMI and higher body fat percentage. In contrast, the genetic markers for anorexia were associated with a lower BMI and lower body fat percentage, though anorexia showed no genetic overlap with naturally being very thin, suggesting its genetics reflect more than just low body weight.
The researchers also found that these eating disorder traits are largely distinct from simple weight regulation. Using a statistical technique to separate out genetic influences shared with BMI, they found that this shared component accounted for only about 12 percent of the genetic signal for binge eating and 10 percent for anorexia, leaving the large majority independent of body weight genetics.
“Anorexia nervosa is not just a consequence of a genetic predisposition to low body weight, and similarly binge eating is not just a response to a genetic predisposition to high body weight,” Coleman explained. “Each has genetic links to the other, and to other psychiatric disorders and traits, but each has unique genetic features too.”
Finally, the team generated polygenic risk scores, which summarize a person’s overall genetic risk based on many small genetic variations. When the researchers applied anorexia risk scores built from the European data to two small studies from Japan and Korea, with about 150 anorexia cases combined, higher scores were linked to higher odds of anorexia, though they explained only about 1.3 percent of the variation in risk. This suggests that some genetic factors for anorexia are shared across ancestries.
“The effects of individual variants on psychiatric traits and disorders in general are very small, but there are a lot of them, and together their effects become similar in size to other risk factors like adverse life events,” Coleman noted. “That is also true for anorexia nervosa and for binge eating.”
“Speaking practically, those individual effects are not very important – most people with the risk version of any given variant won’t binge eat,” he said. “However, the combined set of variants (what we call a polygenic score) has a moderate effect, and we hope that further research can show that it can be useful in future alongside known non-genetic risk factors like family history and history of life events.”
As with all research, there are some caveats to consider. The primary limitation is the heavy reliance on participants of European ancestry. Applying these findings to other global populations requires caution, as differences in genetic background and environments could influence genetic risk.
Because the studies used different ways of identifying cases, and some comparison participants were never screened for eating disorders, the groups may be more mixed than in a clinic-based study. The mostly female sample also means the results may not apply equally to men.
Diagnostic crossover is another factor to keep in mind. People’s eating disorder symptoms can change over time, meaning someone with the restricting subtype of anorexia might develop binge-eating symptoms years later. Because the data relies on cross-sectional studies that take a snapshot in time, some people in one category might eventually migrate to another, though the authors note that diagnostic crossover more likely hides real genetic differences than creates false ones.
Although the combined scores carry real information about risk at the population level, the authors note they remain weak predictors for individuals: in the European data, anorexia scores accounted for about 2.3 percent of the variation in risk and binge-eating scores only about 0.3 percent. They still cannot tell whether a particular person will develop an eating disorder without looking at other risk factors. The authors hope to conduct even larger studies incorporating multiple eating disorder diagnoses and global ancestries to build a more complete biological map.
“It is also important that people understand that this is very much work in progress,” Coleman said. “We don’t fully understand the genetics of either anorexia nervosa or binge eating, and we are still a long way off being able to use genetics to help treat these conditions.”
“But our understanding is sufficient to say that, while genetics plays a role in these conditions, neither is genetically determined, and supportive treatment and supportive social environments can help both,” he concluded.
The study, “Genomic meta-analyses of binge-eating behavior and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes,” was authored by Jet D. Termorshuizen, Helena L. Davies, Sang-Hyuck Lee, Jessica K. Dennis, Christopher Hübel, Jessica S. Johnson, Yi Lu, Melissa A. Munn-Chernoff, Triinu Peters, Baiyu Qi, Katherine E. Schaumberg, Rebecca H. Signer, Karanvir Singh, Abigail R. ter Kuile, Laura M. Thornton, Jiayi Xu, Shuyang Yao, Zeynep Yilmaz, Ruyue Zhang, Johan Zvrskovec, Mohamed Abdulkadir, Ziada Ayorech, Elizabeth C. Corfield, Alexandra Havdahl, Kristi Krebs, Taralynn M. Mack, Maria Niarchou, Teemu Palviainen, Julia M. Sealock, Jessica H. Baker, Andrew W. Bergen, Andreas Birgegård, Vesna Boraska Perica, Katharina Bühren, Roland Burghardt, Matteo Cassina, Giovanni Castellini, Enrico Collantoni, James J. Crowley, Unna N. Danner, Franziska Degenhardt, Janiece E. DeSocio, Christian Dina, Monika Dmitrzak-Węglarz, Laramie E. Duncan, Karin M. Egberts, Lenka Foretova, Ina Giegling, Fragiskos Gonidakis, Scott D. Gordon, Jakob Grove, Sébastien Guillaume, Jerry D. Guintivano, Annette M. Hartmann, Konstantinos Hatzikotoulas, Stefan Herms, Hartmut Imgart, Susana Jiménez-Murcia, Antonio Julià, Gursharan Kalsi, Deborah Kaminská, Leila J. Karhunen, Hannah L. Kennedy, Kirsty M. Kiezebrink, Theresa Kolb, Janne T. Larsen, Dong Li, Lisa Lilenfeld, Mario Maj, Morten Mattingsdal, Paolo Meneguzzo, Allison L. Miller, Karen S. Mitchell, Alessio Maria Monteleone, Catherine M. Olsen, Leonid Padyukov, Richard Parker, Michaela A. Pettie, Dalila Pinto, Anu Raevuori, Samuli Ripatti, Marion E. Roberts, Paolo Santonastaso, Androula Savva, Ulrike H. Schmidt, Alexandra Schosser, Jochen Seitz, Lenka LS Slachtova, Agnieszka Slopien, Sandro Sorbi, Peter S. Straub, Jin P. Szatkiewicz, Friederike I. Tam, Elena Tenconi, Alfonso Tortorella, Artemis Tsitsika, Annemarie A. van Elburg, Gudrun Wagner, Hunna J. Watson, Roger AH Adan, Lars Alfredsson, Ole A. Andreassen, Helga Ask, Anders D. Børglum, Harry A. Brandt, David Collier, Steven Crawford, Scott Crow, Lea K. Davis, Martina de Zwaan, George Dedoussis, Danielle M. Dick, Stefan Ehrlich, Xavier Estivill, Angela Favaro, Fernando Fernández-Aranda, Krista Fischer, Andreas J. Forstner, Philip Gorwood, Hakon Hakonarson, Johannes Hebebrand, Beate Herpertz-Dahlmann, Anke Hinney, James I. Hudson, Craig Johnson, Jennifer Jordan, Allan S. Kaplan, Jaakko Kaprio, Andreas FK Karwautz, Martien JH Kas, Walter H. Kaye, James L. Kennedy, Martin A. Kennedy, Anna Keski-Rahkonen, Youl-Ri Kim, Kelly L. Klump, Mikael Landén, Stéphanie Le Hellard, Kelli Lehto, Qingqin S. Li, Jolanta Lissowska, Jurjen J. Luykx, Sarah L. Maguire, Nicholas G. Martin, Manuel Mattheisen, Sarah E. Medland, Philip Mehler, Nadia Micali, James E. Mitchell, Palmiero Monteleone, Preben Bo Mortensen, Benedetta Nacmias, Roel A. Ophoff, Hana Papezova, Nancy L. Pedersen, Liselotte V. Petersen, Luisa S. Rajcsanyi, Nicolas Ramoz, Ted Reichborn-Kjennerud, Valdo Ricca, Stephan Ripke, Dan Rujescu, Filip Rybakowski, Stephen W. Scherer, Margarita CT Slof-Op ‘t Landt, Howard Steiger, Patrick F. Sullivan, Beata Świątkowska, Eric F. van Furth, Tracey D. Wade, Thomas Werge, David C. Whiteman, D. Blake Woodside, Ya-Ke Wu, Stephan Zipfel, Cynthia M. Bulik, Laura M. Huckins, Gerome Breen, and Jonathan R.I. Coleman.
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#WritersCoffeeClub 18th of October: talk about a time you had a revelation.
I tend to give characters distinct backgrounds, identifiers and outfits, but I don't describe their faces much. Most of them are pretty indistinct beyond "boy with red irises", "red-haired woman in poncho and slouch hat" or things like that.
A few months ago, I realised that I might have prosopagnosia/face blindness. Faces just don't stick in my mind, so it explains a lot about my characters.
Mark Gurman: 'Apple’s iPhone Duo preorders were an absolute disaster'
"Let me cut to the chase: Apple made a major mistake here."
Apple Store looted in French riots
"In Lille, a McDonalds was set on fire, police said, and an Apple store in the city was broken into and looted."
Apple targets nudification
From Malcolm Owen's "AI nudify apps targeted in App Review Guidelines update" posted Saturday by AppleInsider.
https://www.ped30.com/2026/10/18/apple-app-store-nudification/
Apple's iPhone Duo: An 'aspirational foldable'
“It’s not that it’s a breakthrough or new technology, but it’s from Apple." — IDC’s Nabila Popal
This week's Apple trading strategies (10/19-10/23/26)
A place for Apple traders and investors to share their best ideas.
https://www.ped30.com/2026/10/18/apple-trading-stratgies-10-19-26/
A new blog post "Ghidra + CBMC = Assembly Model Checker" https://www.philipzucker.com/asmc_cpp/
A fairly small tool can lift assembly to CBMC's GOTO IR enabling simple cross C-assembly model checking for many ISAs (Ghidra supports 20+ https://github.com/NationalSecurityAgency/ghidra/tree/master/Ghidra/Processors ) #ghidra #assembly #verification
'Extraordinary' says Apple of demand for the iPhone Duo
“The pre-order demand for iPhone Duo, our first foldable iPhone, has been nothing short of extraordinary." — Apple
https://www.ped30.com/2026/10/17/apple-duo-demand-extraordinary/
❎ GRIDHACK will be part of the upcoming Steam Next Fest with a playable demo!
▶️ In GRIDHACK: hacking = fighting nonogram battles
▶️ Try our brand new rogue-lite mode.
▶️ Wishlist now to get notified:
