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April 2026 WikiPathways update: 71 edits by 7 contributorsin and 2 new pathways the last month. More news at https://github.com/wikipathways/wikipathways-help/discussions/231 Accessible via #webservices, #rstats, #pathvisio and #cytoscape. https://www.wikipathways.org/index.php/Download_Pathways
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March 2026 WikiPathways update: 45 edits by 5 contributors in the last month. More news at https://github.com/wikipathways/wikipathways-help/discussions/227
Accessible via #webservices, #rstats, #pathvisio and #cytoscape. Supported by #awsopen. https://www.wikipathways.org/index.php/Download_Pathways
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His contributions to #pathway #curation, #openscience, and the broader #bioinformatics community have left a lasting impact, and we are grateful for everything he has built with this project. Kristina has coordinated our curation efforts from the very beginning, and we are happy that she will remain connected to the project for now through the Google Summer of Code project. 2/
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February 2026 WikiPathways update: 95 edits by 9 contributorsin the last month. More news at https://github.com/wikipathways/wikipathways-help/discussions/221 Accessible via #webservices, #rstats, #pathvisio and #cytoscape. Supported by #awsopen. https://www.wikipathways.org/index.php/Download_Pathways
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January 2026 WikiPathways update: 134 edits by 3 contributorsin the last month. More news at https://github.com/wikipathways/wikipathways-help/discussions/213 Accessible via #webservices, #rstats, #pathvisio and #cytoscape. Supported by #awsopen. https://www.wikipathways.org/index.php/Download_Pathways
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December 2025 WikiPathways release: 840 edits by 8 contributors and 9 new pathways (4 in screenshots). Accessible via #webservices, #rstats, #pathvisio and #cytoscape.
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November 2025 WikiPathways update: 686 edits by 6 contributors and 10 new pathways in the last month. Accessible via #webservices, #rstats, #pathvisio and #cytoscape.
Supported by #awsopen. https://www.wikipathways.org/index.php/Download_Pathways
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October 2025 WikiPathways update: 129 edits by 10 contributors and 5 new pathways in the last month. Accessible via #webservices, #rstats, #pathvisio and #cytoscape. Supported by #awsopen. https://www.wikipathways.org/index.php/Download_Pathways
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September 2025 WikiPathways update: 261 edits by 6 contributors and 13 new pathways in the last month. Accessible via #webservices, #rstats, #pathvisio and #cytoscape. Supported by #awsopen. https://www.wikipathways.org/index.php/Download_Pathways
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June 2025 WikiPathways release: 338 edits by 15 contributors and 9 new pathways. https://data.wikipathways.org/
Accessible via #webservices, #rstats, Pathvisio, and Cytoscape.
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May 2025 WikiPathways release: 491 edits by 9 contributors and 8 new pathways.
Accessible via #webservices, #rstats, Pathvisio, and Cytoscape.
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Bioactivated Glucoraphanin Modulates Genes Involved in Necroptosis on Motor-Neuron-like Nsc-34: A Transcriptomic Study. https://doi.org/10.3390/antiox13091111 #Glucosinolates #Isothiocyanates #TranscriptomicAnalysis #PathwayAnalysis #OxidativeStress
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October 2024 WikiPathways update: 167 edits by 4 contributors and 2 new pathways in the last month. Accessible via #webservices, #rstats, #pathvisio and #Cytoscape Supported by #AWSOpen
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September 2024 WikiPathways update: 179 edits by 6 contributors and 4 new pathways in the last month. Accessible via #webservices, #rstats, #pathvisio and #cytoscape. Supported by #awsopen . https://wikipathways.org/index.php/Download_Pathways
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A Transcriptomic Biomarker Predicting Linezolid-Associated Neuropathy During Treatment of Drug-Resistant Tuberculosis. https://doi.org/10.20411/pai.v9i2.705 #AdverseEvents #Linezolid #Neurotoxicity #PrecisionMedicine #Sbsn
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A novel insight into neurological disorders through HDAC6 protein–protein interactions. https://doi.org/10.1038/s41598-024-65094-1 #HistoneDeacetylase6 #Protein–ProteinInteractions #CentralNervousSystem #Alzheimer’sDisease #Parkinson’sDisease
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Gastric cancer actionable genomic alterations across diverse populations worldwide and pharmacogenomics strategies based on precision oncology. https://doi.org/10.3389/fphar.2024.1373007 #GastricCancer #PrecisionOncology #EthnicGroups #GenomicAlterations #TherapeuticStrategies
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Transcriptome- and proteome-wide effects of a circular RNA encompassing four early exons of the spinal muscular atrophy genes. https://doi.org/10.1038/s41598-024-60593-7 #SpinalMuscularAtrophy,Sma #SurvivalMotorNeuron,Smn #CircularRna,Circrna #Proteome #Transcriptome
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A patient-based iPSC-derived hepatocyte model of alcohol-associated cirrhosis reveals bioenergetic insights into disease pathogenesis. https://doi.org/10.1038/s41467-024-47085-y #StemCellResearch #Hepatology #TranslationalResearch
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Neuroprotective effect of acetoxypachydiol against oxidative stress through activation of the Keap1-Nrf2/HO-1 pathway. https://doi.org/10.1186/s12906-024-04474-6 #Acetoxypachydiol #NeuroprotectiveEffect #Keap1Nrf2/Ho1Pathway #OxidativeStress
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PPARγ attenuates cellular senescence of alveolar macrophages in asthma-COPD overlap. https://doi.org/10.1186/s12931-024-02790-6 #Aco #Asthma #Copd #Macrophages #Senescence
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CDKN2A-p16 Deletion and Activated KRASG12D Drive Barrett’s-Like Gland Hyperplasia-Metaplasia and Synergize in the Development of Dysplasia Precancer Lesions. https://doi.org/10.1016/j.jcmgh.2024.01.014 #Dysplasia #EsophagealAdenocarcinoma #3dOrganoids #Transcriptomics
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Metabolomics Reveals Lysinibacillus capsici TT41-Induced Metabolic Shifts Enhancing Drought Stress Tolerance in Kimchi Cabbage (Brassica rapa L. subsp. pekinensis). https://doi.org/10.3390/metabo14020087 #DroughtStress #AbioticStress #LacticAcid #Metabolomics #BrassicaRapa
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Deregulation of miR‐1245b‐5p and miR‐92a‐3p and their potential target gene, GATA3, in epithelial–mesenchymal transition pathway in breast cancer. https://doi.org/10.1002/cnr2.1955 #BreastCancer #Epithelial‐MesenchymalTransition #Gata3 #Micrornas
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Transcriptomic and Proteomic of Gastrocnemius Muscle in Peripheral Artery Disease. https://doi.org/10.1161/CIRCRESAHA.122.322325 #Biomarkers #BasicScienceResearch #ClinicalStudies #Inflammation #VascularBiology
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Exploring the mechanisms of glycolytic genes involvement in pulmonary arterial hypertension through integrative bioinformatics analysis. https://doi.org/10.1111/jcmm.18447 #Bioinformatics #Degs #Glycolysis #MachineLearning #Pah
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Identifying Differences in Molecular Characteristics Relevant for Remodeling of Periodontal Ligament Stem Cells from the Upper and Lower Jaw. https://doi.org/10.3390/ijms25063207 #KinaseActivity #PeriodontalLigamentStemCells #Mandible #Maxilla #Tyrosine
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March 2024 WikiPathways release: 542 edits by 9 contributors and 10 new pathways. Accessible via #webservices and in #PathVisio, #Cytoscape. Supported by AWSOpen. https://wikipathways.org/#download #bioinformatics #openscience #opensource
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Insight into the mechanism of gallstone disease by proteomic and metaproteomic characterization of human bile. https://doi.org/10.3389/fmicb.2023.1276951 #Bile #Metaproteomics #Gallstone #Microbiome #Proteomics
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The Role of Amino Acid Metabolism of Tumor Associated Macrophages in the Development of Colorectal Cancer. https://doi.org/10.3390/cells11244106 #ColorectalCancer #TumorMicroenvironment #AminoAcidMetabolism #TumorAssociatedMacrophages #CellDeath
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Transcriptional profiling of phagocytic leukocytes and microglia reveals a critical role for reactive oxygen species in biofilm containment during Staphylococcus aureus craniotomy infection. https://doi.org/10.4049/jimmunol.2200503 #StaphylococcusAureus #Biofilm #CraniotomyInfection #Microglia #Neutrophils
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Sedanolide Activates KEAP1–NRF2 Pathway and Ameliorates Hydrogen Peroxide-Induced Apoptotic Cell Death. https://doi.org/10.3390/ijms242216532 #Sedanolide #Are #Nrf2 #OxidativeStress #Apoptosis
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Sex as a Predictor of Response to Immunotherapy in Advanced Cutaneous Squamous Cell Carcinoma. https://doi.org/10.3390/cancers15205026 #CutaneousSquamousCellCancer #Immunotherapy #Sex #TCell #Biomarkers
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Diffusion tensor imaging‐based machine learning for IDH wild‐type glioblastoma stratification to reveal the biological underpinning of radiomic features. https://doi.org/10.1111/cns.14263 #BiologicalPathway #DiffusionTensorImaging #Glioblastoma #MachineLearning #Prognosis
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IGF2BP2-meidated m6A modification of CSF2 reprograms MSC to promote gastric cancer progression. https://doi.org/10.1038/s41419-023-06163-7 #MesenchymalStemCells #Reprogramming
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Deregulated miRNA Expression in Triple-Negative Breast Cancer of Ancestral Genomic-Characterized Latina Patients. https://doi.org/10.3390/ijms241713046 #TripleNegativeBreastCancer #Latinas #CopyNumberAlterations #Microrna #Mirna
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Potential of miRNAs in Plasma Extracellular Vesicle for the Stratification of Prostate Cancer in a South African Population. https://doi.org/10.3390/cancers15153968 #ProstateCancer #ExtracellularVesicles #Exosomes #Mirna #Mir1945p
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A novel orthotopic mouse model replicates human lung cancer cachexia. https://doi.org/10.1002/jcsm.13222 #CancerCachexia #LungCancer #MuscleWasting #MouseModel #OrthotopicMouseModel
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Deciphering the Molecular Mechanisms of Autonomic Nervous System Neuron Induction through Integrative Bioinformatics Analysis. https://doi.org/10.3390/ijms24109053 #AutonomicNervousSystem #Bioinformatics #HumanInducedPluripotentStemCells
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Extracellular arginine availability modulates eIF2α O-GlcNAcylation and heme oxygenase 1 translation for cellular homeostasis. https://doi.org/10.1186/s12929-023-00924-4 #Arginine #OGlcnacylation #EukaryoticInitiationFactor2α #ProteinTranslation #HemeOxygenase1
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Microbial Communities in Gynecological Cancers and Their Association with Tumor Somatic Variation. https://doi.org/10.3390/cancers15133316 #MicrobialCommunities #Metagenomics #HighGradeSerousOvarianCancer #EndometrioidEndometrialCancer #Bacterial
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July 2023 WikiPathways release: 232 edits by 32 contributors and 12 new pathways. Accessible via #webservices and in #PathVisio, #Cytoscape Supported by AWSOpen. https://wikipathways.org/#download #bioinformatics #openscience #opensource
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June 2023 WikiPathways release: 137 edits by 22 contributors and 2 new pathways. Accessible via #webservices and in #PathVisio, #Cytoscape Supported by AWSOpen. https://wikipathways.org/#download
#bioinformatics #openscience #opensource -
May 2023 WikiPathways release: 316 edits by 13 contributors and 15 new pathways. Accessible via #webservices and in #PathVisio, #Cytoscape. Supported by #AWSOpen. https://www.wikipathways.org/download.html
#bioinformatics #openscience #opensource #nomoa -
April 2023 WikiPathways release: 276 edits by 32 contributors and 6 new pathways. Accessible via #webservices and in #PathVisio, #Cytoscape. Supported by #AWSOpen. https://www.wikipathways.org/download.html
#bioinformatics #openscience #opensource #nomoa -
A molecular network map of orexin-orexin receptor signaling system. https://doi.org/10.1007/s12079-022-00700-3 #Orexin #Pathvisio #Sleep #Feeding #Hypothalamus
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March 2023 WikiPathways release: 293 edits by 30 contributors and 22 new pathways. Accessible via #webservices and in #PathVisio, #Cytoscape. Supported by #AWSOpen. https://www.wikipathways.org/download.html
#bioinformatics #openscience #opensource #nomoa -
February 2023 WikiPathways release: 283 edits by 32 contributors. Accessible via #webservices and in #PathVisio, #Cytoscape. Supported by #AWSOpen. https://wikipathways.org/index.php/Download_Pathways
#bioinformatics #openscience #opensource #nomoa -
The Mixture of Ferulic Acid and P-Coumaric Acid Suppresses Colorectal Cancer through lncRNA 495810/PKM2 Mediated Aerobic Glycolysis. https://doi.org/10.3390/ijms232012106 #Polyphenol #Lncrna495810 #Pkm2
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Genetic Factors for Coronary Heart Disease and Their Mechanisms: A Meta-Analysis and Comprehensive Review of Common Variants from Genome-Wide Association Studies. https://doi.org/10.3390/diagnostics12102561 #CommonVariants #CoronaryHeartDisease #Genome-WideAssociationStudy