#apoptosis — Public Fediverse posts

https://www.europesays.com/ie/525423/ Study identifies new therapeutic candidate for KRAS-driven pancreatic cancer #Actin #Apoptosis #cancer #Cell #CellDeath #CellMigration #Compound #Éire #Genes #IE #Ireland #Metastasis #PancreaticCancer #Reproduction #Research #Science #Tumor

Dose-dependent effects of wheat germ oil and vitamin E on apoptosis and gene expression in breast and cervical cancer cell lines with single-cell RNA-seq profiling

Data collection and processing We obtained the scRNA-seq (Sing…
#Germany #DE #Europe #EU #Europa #E.ON #Apoptosis #Breastcancer #cancer #Cancergenetics #Cervicalcancer #E.ONSE #HeLa #HumanitiesandSocialSciences #MCF-7 #multidisciplinary #Science #Single-cellRNA-seq #Wheatgermoil #Α-Tocopherol
https://www.europesays.com/germany/24059/

Kyoto University identifies a key regulator of insulin production

A hallmark of Type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas that pro…
#Japan #JP #Kyoto #Apoptosis #cell #CellProliferation #Chronic #diabetes #diet #invitro #invivo #insulin #kyotonews #news #Pancreas #pregnancy #Proliferation #Protein #research #RNA #stress #Transcription #Type2Diabetes #京都 #京都府
https://www.alojapan.com/1483546/kyoto-university-identifies-a-key-regulator-of-insulin-production/

Kyoto University identifies a key regulator of insulin production

A hallmark of Type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas that pro…
#Japan #JP #Kyoto #Apoptosis #cell #CellProliferation #Chronic #diabetes #diet #invitro #invivo #insulin #kyotonews #news #Pancreas #pregnancy #Proliferation #Protein #research #RNA #stress #Transcription #Type2Diabetes #京都 #京都府
https://www.alojapan.com/1483546/kyoto-university-identifies-a-key-regulator-of-insulin-production/

https://www.alojapan.com/1483546/kyoto-university-identifies-a-key-regulator-of-insulin-production/ Kyoto University identifies a key regulator of insulin production #Apoptosis #cell #CellProliferation #Chronic #diabetes #diet #InVitro #InVivo #insulin #Kyoto #KyotoNews #news #Pancreas #pregnancy #Proliferation #Protein #research #RNA #stress #Transcription #Type2Diabetes #京都 #京都府 A hallmark of Type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas that produce and release insulin. The endoplasmic reticulum stress

https://www.alojapan.com/1483546/kyoto-university-identifies-a-key-regulator-of-insulin-production/ Kyoto University identifies a key regulator of insulin production #Apoptosis #cell #CellProliferation #Chronic #diabetes #diet #InVitro #InVivo #insulin #Kyoto #KyotoNews #news #Pancreas #pregnancy #Proliferation #Protein #research #RNA #stress #Transcription #Type2Diabetes #京都 #京都府 A hallmark of Type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas that produce and release insulin. The endoplasmic reticulum stress

https://www.europesays.com/ie/472818/ Kyoto University identifies key regulator of insulin production #Apoptosis #Cell #CellProliferation #Chronic #diabetes #diet #Éire #IE #InVitro #InVivo #Insulin #Ireland #Pancreas #Pregnancy #Proliferation #Protein #Research #RNA #Science #Stress #Transcription #Type2Diabetes

https://www.europesays.com/ie/445809/ APC-deficient cancer cells rely on single enzyme for survival #Apoptosis #cancer #Cell #CellBiology #CellDeath #CellProliferation #Colorectal #ColorectalCancer #Éire #Enzyme #Gene #Genes #Genetic #Health #IE #Ireland #Oxygen #Proliferation #Research #Stress

https://www.europesays.com/ie/424450/ Blocking nitric oxide suppresses tumor growth in aggressive pediatric neuroblastoma #Apoptosis #blood #BloodVessels #Brain #cancer #Cell #DNA #Éire #Enzyme #Genetic #Genomic #Glioblastoma #Health #IE #Ireland #medicine #Neuroblastoma #Neurons #Neuroscience #NitricOxide #Phosphorylation #Protein #Research #siRNA #Stress #Tumor #website #Xenograft

"These findings suggest a fundamental mechanism by which cancer cells may evade apoptosis by exploiting Bcl-2’s ability to neutralize Bax through structural entrapment, even if excess Bax is present, either in response to treatment or natural death signals."

http://dx.doi.org/10.1021/acschembio.5c00913

#apoptosis #oncology #biochemistry #molecularBiology #biology #cancer

"These findings suggest a fundamental mechanism by which cancer cells may evade apoptosis by exploiting Bcl-2’s ability to neutralize Bax through structural entrapment, even if excess Bax is present, either in response to treatment or natural death signals."

http://dx.doi.org/10.1021/acschembio.5c00913

#apoptosis #oncology #biochemistry #molecularBiology #biology #cancer

Palmatine improved fatty liver markers in a preclinical type 2 diabetes study

A new preclinical study suggests that palmatine may ease diabetes-linked…
#NewsBeep #News #Health #Alanine #Apoptosis #AU #Australia #bioinformatics #Cell #CellDeath #cholesterol #Cirrhosis #diabetes #FattyLiver #Gene #GeneExpression #Genes #Glucose #Inflammation #Insulin #Kinase #Liver #LiverDisease #Metabolism #OxidativeStress #Preclinical #protein #research #stress #type2diabetes
https://www.newsbeep.com/au/560406/

Palmatine improved fatty liver markers in a preclinical type 2 diabetes study

A new preclinical study suggests that palmatine may ease diabetes-linked…
#NewsBeep #News #Health #Alanine #Apoptosis #AU #Australia #bioinformatics #Cell #CellDeath #cholesterol #Cirrhosis #diabetes #FattyLiver #Gene #GeneExpression #Genes #Glucose #Inflammation #Insulin #Kinase #Liver #LiverDisease #Metabolism #OxidativeStress #Preclinical #protein #research #stress #type2diabetes
https://www.newsbeep.com/au/560406/

https://www.europesays.com/ie/381151/ CSF1R T567M mutation induces microglial dysfunction and synaptic impairment in patient iPSC-derived cerebral organoids of CSF1R-related disorder #Apoptosis #Biochemistry #CellBiology #CellCycleAnalysis #Éire #general #Health #IE #Immunopathogenesis #Ireland #LifeSciences #Neurodegeneration #Neurogenesis #StemCells #StemCellResearch

https://www.europesays.com/ie/376820/ Enzyme helps maintain retinal progenitor cells during eye development #Apoptosis #Brain #Cell #Chromatin #DNA #DNADamage #Éire #Enzyme #eye #Gene #Genes #IE #Ireland #Laboratory #Neurons #ProgenitorCells #Proliferation #Protein #Research #Science #Technology

https://www.europesays.com/ie/372252/ TREM2 helps macrophages survive and repair radiation damaged skin #Apoptosis #Éire #hospital #IE #Ireland #Macrophage #radiotherapy #Research #Science #skin #Stress #Technology #Wound #WoundHealing

Sustained high progesterone during pregnancy can improve menstrual cyclicity in PCOS patients

Polycystic ovary syndrome (PCOS) affects 6%−20% of reproductive-aged women, and is commonly accompanied by irregular menstrual cycles and…
#NewsBeep #News #Health #Apoptosis #AU #Australia #Cell #Hormone #Infertility #menstrualcycle #Metabolism #MouseModel #polycysticovarysyndrome #pregnancy #Progesterone #Syndrome
https://www.newsbeep.com/au/473361/

https://www.europesays.com/ie/246898/ Reframing the role of MCL1 in cancer signaling and metabolism #Apoptosis #cancer #CancerTherapy #Cell #CellDeath #Éire #Health #IE #Ireland #medicine #Metabolism #ProgrammedCellDeath #Protein #Research #Technology #therapy #Tumor

Reframing the role of MCL1 in cancer signaling and metabolism

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD…
#NewsBeep #News #Health #Apoptosis #CA #Canada #cancer #CancerTherapy #Cell #CellDeath #medicine #Metabolism #ProgrammedCellDeath #Protein #research #Technology #therapy #Tumor
https://www.newsbeep.com/ca/362971/

`We report that plasma concentrations of ubiquitin C-terminal hydrolase-L1 (UCH-L1) and neurofilament light (NfL) become exponentially higher from ages 2 to 85 in cross-sectional samples, serving as neuronal death/damage biomarkers across the lifespan.`

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00598-1

#biomarker #lifespan #aging #biology #ubiquitin #apoptosis #neuron #neuronal #neuroscience #neurodegeneration #disease #brain

`We report that plasma concentrations of ubiquitin C-terminal hydrolase-L1 (UCH-L1) and neurofilament light (NfL) become exponentially higher from ages 2 to 85 in cross-sectional samples, serving as neuronal death/damage biomarkers across the lifespan.`

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00598-1

#biomarker #lifespan #aging #biology #ubiquitin #apoptosis #neuron #neuronal #neuroscience #neurodegeneration #disease #brain

`We report that plasma concentrations of ubiquitin C-terminal hydrolase-L1 (UCH-L1) and neurofilament light (NfL) become exponentially higher from ages 2 to 85 in cross-sectional samples, serving as neuronal death/damage biomarkers across the lifespan.`

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00598-1

#biomarker #lifespan #aging #biology #ubiquitin #apoptosis #neuron #neuronal #neuroscience #neurodegeneration #disease #brain

`We report that plasma concentrations of ubiquitin C-terminal hydrolase-L1 (UCH-L1) and neurofilament light (NfL) become exponentially higher from ages 2 to 85 in cross-sectional samples, serving as neuronal death/damage biomarkers across the lifespan.`

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00598-1

#biomarker #lifespan #aging #biology #ubiquitin #apoptosis #neuron #neuronal #neuroscience #neurodegeneration #disease #brain

`We report that plasma concentrations of ubiquitin C-terminal hydrolase-L1 (UCH-L1) and neurofilament light (NfL) become exponentially higher from ages 2 to 85 in cross-sectional samples, serving as neuronal death/damage biomarkers across the lifespan.`

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00598-1

#biomarker #lifespan #aging #biology #ubiquitin #apoptosis #neuron #neuronal #neuroscience #neurodegeneration #disease #brain

https://www.europesays.com/ie/224925/ Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells #Adenosine #AdenosineTriphosphate #Apoptosis #CardiovascularDisease #Cell #chemotherapy #DNA #DoubleMembrane #Doxorubicin #Drugs #Éire #Gene #IE #InVitro #InVivo #Ireland #Membrane #MesenchymalStemCells #Metabolism #Mitochondria #Molecule #Muscle #Protein #Research #Science #StemCells #Stress

Tattoo ink alters immune cells and weakens some vaccine responses

New research reveals that tattoo pigments don’t just stay in the skin, they migrate…
#NewsBeep #News #Health #Antibody #Apoptosis #AU #Australia #Cell #CellDeath #coronavirus #covid-19 #Electron #ElectronMicroscopy #ImmuneResponse #immunity #invitro #invivo #Inflammation #influenza #LymphNode #LymphNodes #lymphaticsystem #Macrophage #Microscopy #research #RibonucleicAcid #Skin #tattoos #Vaccine
https://www.newsbeep.com/au/312307/

https://www.europesays.com/ie/202772/ Tattoo ink alters immune cells and weakens some vaccine responses #Antibody #Apoptosis #Cell #CellDeath #Coronavirus #Covid19 #Éire #Electron #ElectronMicroscopy #Health #IE #ImmuneResponse #immunity #InVitro #InVivo #inflammation #Influenza #Ireland #LymphNode #LymphNodes #LymphaticSystem #Macrophage #Microscopy #Research #RibonucleicAcid #skin #Tattoos #Vaccine

In the fight against disease, programmed cell death – also known as #apoptosis – is a key protective function of the body. It breaks down cells that are damaged or have undergone dangerous changes.
#Biochemistry #sflorg
https://www.sflorg.com/2025/11/bchm11032501.html

In the fight against disease, programmed cell death – also known as #apoptosis – is a key protective function of the body. It breaks down cells that are damaged or have undergone dangerous changes.
#Biochemistry #sflorg
https://www.sflorg.com/2025/11/bchm11032501.html

#Kulturkampf #Medizin

.. promise in modulating numerous processes associated with #neurodegenerativediseases, #cancer, #epilepsy, and #traumaticbraininjury [Table 1]. In addition, the #ECS is known to influence #neuroplasticity, #apoptosis, #excitotoxicity, #neuroinflammation, and #cerebrovascularbreakdown associated with #stroke and #trauma.[105]

https://pmc.ncbi.nlm.nih.gov/articles/PMC5938896/

#WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana
#Streeck 🙏 #NinaWarken 🙏
Herr #Merz #Söder #Klingbeil 😀 #Cannabis

Trying to think of a better phrase than "AI Bubble".
How about "AIpoptosis"?
Really depends on anything useful being left behind!

#AIBubble #apoptosis #AIpoptosis #AI

Wikipedia, Apoptosis

In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis is a highly regulated and controlled process that confers advantages during an organism's life cycle. For example, the separation of fingers and toes in a developing human embryo occurs because cells between the digits undergo a form of apoptosis that is genetically determined. Unlike necrosis, apoptosis produces cell fragments called apoptotic bodies that phagocytes are able to engulf and remove before the contents of the cell can spill out onto surrounding cells and cause damage to them.

https://en.wikipedia.org/wiki/Apoptosis

Trying to think of a better phrase than "AI Bubble".
How about "AIpoptosis"?
Really depends on anything useful being left behind!

#AIBubble #apoptosis #AIpoptosis #AI

Wikipedia, Apoptosis

In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis is a highly regulated and controlled process that confers advantages during an organism's life cycle. For example, the separation of fingers and toes in a developing human embryo occurs because cells between the digits undergo a form of apoptosis that is genetically determined. Unlike necrosis, apoptosis produces cell fragments called apoptotic bodies that phagocytes are able to engulf and remove before the contents of the cell can spill out onto surrounding cells and cause damage to them.

https://en.wikipedia.org/wiki/Apoptosis

Blocking GAPDH aggregation protects brain cells and opens new path for stroke therapy

A novel study reveals that targeting a single protein’s aggregation can dramatically reduce brain injury after stroke, potentially…
#NewsBeep #News #Health #Apoptosis #AU #Australia #Blood #Brain #Cell #CellDeath #Cortex #dna #IschemicStroke #Kinase #Metabolism #Necrosis #OxidativeStress #protein #stress #Stroke #Transgenic
https://www.newsbeep.com/au/9860/

Grundlagenwissen ist kein Luxus – es ist die Basis jeder soliden Forschung. Deshalb nehmen wir uns im Team Zeit dafür – bewusst, regelmäßig, gemeinsam. #LehreImLabor #IF #IHC #Apoptosis #Zelltod #SevenichLab

Grundlagenwissen ist kein Luxus – es ist die Basis jeder soliden Forschung. Deshalb nehmen wir uns im Team Zeit dafür – bewusst, regelmäßig, gemeinsam. #LehreImLabor #IF #IHC #Apoptosis #Zelltod #SevenichLab

Caspases have well known roles in #apoptosis, but roles in other cellular processes are emerging... This study shows that #caspase -3 & -7 promote cytoprotective #autophagy in response to non-lethal stress by modulating PARP1 activity in #BreastCancer cells #plosbiology https://plos.io/41xfLVm

Caspases have well known roles in #apoptosis, but roles in other cellular processes are emerging... This study shows that #caspase -3 & -7 promote cytoprotective #autophagy in response to non-lethal stress by modulating PARP1 activity in #BreastCancer cells #plosbiology https://plos.io/41xfLVm

Caspases have well known roles in #apoptosis, but roles in other cellular processes are emerging... This study shows that #caspase -3 & -7 promote cytoprotective #autophagy in response to non-lethal stress by modulating PARP1 activity in #BreastCancer cells #plosbiology https://plos.io/41xfLVm

Caspases have well known roles in #apoptosis, but roles in other cellular processes are emerging... This study shows that #caspase -3 & -7 promote cytoprotective #autophagy in response to non-lethal stress by modulating PARP1 activity in #BreastCancer cells #plosbiology https://plos.io/41xfLVm

Caspases have well known roles in #apoptosis, but roles in other cellular processes are emerging... This study shows that #caspase -3 & -7 promote cytoprotective #autophagy in response to non-lethal stress by modulating PARP1 activity in #BreastCancer cells #plosbiology https://plos.io/41xfLVm

I'm extracting DNA from the legs of spiders which were euthanized by freezing in a household freezer. In almost every spider, the DNA shows a banding pattern associated with apoptosis. Why would there be so much programed cell death in the legs of spiders? Had it already happened naturally? Was it induced during the freezing process? I do not see this happening in other organisms using the same extraction procedure.

Each lane is DNA extracted from a different spider.

#genetics #DNA #apoptosis

I'm extracting DNA from the legs of spiders which were euthanized by freezing in a household freezer. In almost every spider, the DNA shows a banding pattern associated with apoptosis. Why would there be so much programed cell death in the legs of spiders? Had it already happened naturally? Was it induced during the freezing process? I do not see this happening in other organisms using the same extraction procedure.

Each lane is DNA extracted from a different spider.

#genetics #DNA #apoptosis

For #epithelial tissue homeostasis, cell elimination & proliferation must balance. @DaikiUmetsu &co show that faster cell removal is associated with switch from isolated to clustered #apoptosis, induced by ⬇️ #endocytosis & EGFR signaling #PLOSBiology https://plos.io/403rQ3Y

For #epithelial tissue homeostasis, cell elimination & proliferation must balance. @DaikiUmetsu &co show that faster cell removal is associated with switch from isolated to clustered #apoptosis, induced by ⬇️ #endocytosis & EGFR signaling #PLOSBiology https://plos.io/403rQ3Y

What are the effects of #centrosome amplification in #cancer? @basto_lab &co show that extra centrosomes prime #OvarianCancer cells for #apoptosis, acting in synergy with #chemotherapy to induce cell death, correlating with improved survival #PLOSBiology https://plos.io/4dbmpD7

What are the effects of #centrosome amplification in #cancer? @basto_lab &co show that extra centrosomes prime #OvarianCancer cells for #apoptosis, acting in synergy with #chemotherapy to induce cell death, correlating with improved survival #PLOSBiology https://plos.io/4dbmpD7

Researchers examine #protein arrangement in #cell_membrane that triggers programmed cell death

#apoptosis #CD95_receptor #signalling #image_spectroscopy #microscopy

https://phys.org/news/2024-09-protein-cell-membrane-triggers-death.html

Researchers examine #protein arrangement in #cell_membrane that triggers programmed cell death

#apoptosis #CD95_receptor #signalling #image_spectroscopy #microscopy

https://phys.org/news/2024-09-protein-cell-membrane-triggers-death.html

How do cells respond to defects in nuclear reassembly after #mitosis? This study in #Drosophila shows that damaged cells are either removed by #apoptosis or activate a p53-dependent #CellCycle checkpoint to maintain tissue integrity #PLOSBiology https://plos.io/3AA4g4c

How do cells respond to defects in nuclear reassembly after #mitosis? This study in #Drosophila shows that damaged cells are either removed by #apoptosis or activate a p53-dependent #CellCycle checkpoint to maintain tissue integrity #PLOSBiology https://plos.io/3AA4g4c