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#apoptosis — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #apoptosis, aggregated by home.social.

  1. PLOS Biology @[email protected] ·

    How does the Wnt pathway promote resistance to #DNAdamage induced by #IonizingRadiation? @BenForWard3 &co show that #WntSignaling modulates DNA damage response via EGFR in #Drosophila, protecting cells from #apoptosis induced by DNA ds breaks #PLOSBiology plos.io/4dduEiq

    #dnadamage #ionizingradiation #wntsignaling #drosophila #apoptosis #plosbiology
  2. Johan Spetz @[email protected] ·

    Check out our recent paper on #vascular cell apoptotic vulnerabilities to #cancer therapeutics, including #radiotherapy, #chemotherapy and targeted agents (e.g. #proteasome inhibitors, #BH3mimetics). We find that #EndothelialCells remain primed for #apoptosis throughout development into adulthood and may represent a “weakest link” vulnerability in multiple tissues for development of toxicities. science.org/doi/full/10.1126/s

    #Celldeath #CardioOncology #VigiBase #RadioBiology #BH3Profiling

    #vascular #cancer #radiotherapy #chemotherapy #proteasome #bh3mimetics