#hepatology — Public Fediverse posts

Liver fibrosis is driven by two specific proteins, SEMA4D and LMCD1, which can be therapeutically blocked to halt and potentially reverse progressive liver scarring.
#MolecularBiology #CellBiology #Pathology #Hepatology #sflorg
https://www.sflorg.com/2026/05/mbio05142601.html

Liver fibrosis is driven by two specific proteins, SEMA4D and LMCD1, which can be therapeutically blocked to halt and potentially reverse progressive liver scarring.
#MolecularBiology #CellBiology #Pathology #Hepatology #sflorg
https://www.sflorg.com/2026/05/mbio05142601.html

Liver fibrosis is driven by two specific proteins, SEMA4D and LMCD1, which can be therapeutically blocked to halt and potentially reverse progressive liver scarring.
#MolecularBiology #CellBiology #Pathology #Hepatology #sflorg
https://www.sflorg.com/2026/05/mbio05142601.html

Liver fibrosis is driven by two specific proteins, SEMA4D and LMCD1, which can be therapeutically blocked to halt and potentially reverse progressive liver scarring.
#MolecularBiology #CellBiology #Pathology #Hepatology #sflorg
https://www.sflorg.com/2026/05/mbio05142601.html

Liver fibrosis is driven by two specific proteins, SEMA4D and LMCD1, which can be therapeutically blocked to halt and potentially reverse progressive liver scarring.
#MolecularBiology #CellBiology #Pathology #Hepatology #sflorg
https://www.sflorg.com/2026/05/mbio05142601.html

Researchers have identified a novel cluster of liver cells (hepatocytes) that specifically emerge during metabolic dysfunction-associated steatohepatitis (MASH). These cells exhibit unique gene expression and cellular senescence, acting as a critical regulator of liver disease progression.
#Hepatology #CellBiology #DevelopmentalBiology #MolecularGenetics #sflorg
https://www.sflorg.com/2026/05/bio05042601.html

Researchers have identified a novel cluster of liver cells (hepatocytes) that specifically emerge during metabolic dysfunction-associated steatohepatitis (MASH). These cells exhibit unique gene expression and cellular senescence, acting as a critical regulator of liver disease progression.
#Hepatology #CellBiology #DevelopmentalBiology #MolecularGenetics #sflorg
https://www.sflorg.com/2026/05/bio05042601.html

Researchers have identified a novel cluster of liver cells (hepatocytes) that specifically emerge during metabolic dysfunction-associated steatohepatitis (MASH). These cells exhibit unique gene expression and cellular senescence, acting as a critical regulator of liver disease progression.
#Hepatology #CellBiology #DevelopmentalBiology #MolecularGenetics #sflorg
https://www.sflorg.com/2026/05/bio05042601.html

Researchers have identified a novel cluster of liver cells (hepatocytes) that specifically emerge during metabolic dysfunction-associated steatohepatitis (MASH). These cells exhibit unique gene expression and cellular senescence, acting as a critical regulator of liver disease progression.
#Hepatology #CellBiology #DevelopmentalBiology #MolecularGenetics #sflorg
https://www.sflorg.com/2026/05/bio05042601.html

Researchers have identified a novel cluster of liver cells (hepatocytes) that specifically emerge during metabolic dysfunction-associated steatohepatitis (MASH). These cells exhibit unique gene expression and cellular senescence, acting as a critical regulator of liver disease progression.
#Hepatology #CellBiology #DevelopmentalBiology #MolecularGenetics #sflorg
https://www.sflorg.com/2026/05/bio05042601.html

https://www.europesays.com/ie/458402/ Hepatitis C infection associated with reduced portal insulin levels #blood #Cytokines #Éire #Glucose #Health #Hepatitis #HepatitisC #Hepatology #IE #ImmuneResponse #ImmuneSystem #Insulin #InsulinResistance #Ireland #Liver #Metabolism #Research #virus

Fatty degeneration of hepatocytes (fatty hepatosis) #hepatology #hepatocytes #liver #liverhealth ... Continue to: https://www.facebook.com/reel/1287457032793329/

Fatty degeneration of hepatocytes (fatty hepatosis) #hepatology #hepatocytes #liver #liverhealth ... Continue to: https://www.facebook.com/reel/1287457032793329/

Fatty degeneration of hepatocytes (fatty hepatosis) #hepatology #hepatocytes #liver #liverhealth ... Continue to: https://www.facebook.com/reel/1287457032793329/

APASL 2026 Day 1 — What’s shaping hepatology right now?

From HEV insights to HBV biomarkers and AI-driven fibrosis prediction — key discussions are already setting the tone for clinical practice.

We’ve curated the most relevant highlights so you don’t miss what truly matters.

👉 Explore full updates on GastroAGI

#GastroAGI #APASL2026 #Hepatology #LiverDisease #HBV #HEV #MASLD #HCC #MedicalEducation #GIUpdates #MedEd #ClinicalInsights

https://www.europesays.com/ie/450856/ Study identifies key risk factors driving MASLD across populations #Alanine #diabetes #Éire #ElectronicHealthRecord #Frequency #Health #Hepatology #Hyperlipidemia #Hypothyroidism #IE #Ireland #Liver #LiverDisease #Obesity #ObstructiveSleepApnea #Phosphatase #Research #Sleep #SleepApnea #Type2Diabetes

https://www.europesays.com/ie/450150/ Restoring gut microbiome may prevent liver cancer in mice #Aging #cancer #Éire #Endoscopy #FecalMicrobiotaTransplantation #Gastroenterology #Health #Hepatology #IE #inflammation #Ireland #Liver #LiverCancer #Microbiome #Research #Surgery

Gut microbiome characteristics predict treatment response in IBS-D patients

In a new study published in Clinical Gastroenterology and Hepatology, the low FODMAP diet and the antibiotic rifaximin provided similar and signif…
#NewsBeep #News #Health #AbdominalPain #antibiotic #AU #Australia #Bloating #Diarrhea #diet #FODMAP #gastroenterology #Hepatology #IrritableBowelSyndrome #MedicalSchool #medicine #Microbiome #Pain #research #Syndrome #Therapeutics #therapy
https://www.newsbeep.com/au/624229/

Gut microbiome characteristics predict treatment response in IBS-D patients

In a new study published in Clinical Gastroenterology and Hepatology, the low FODMAP diet and the antibiotic rifaximin provided similar and signif…
#NewsBeep #News #Health #AbdominalPain #antibiotic #AU #Australia #Bloating #Diarrhea #diet #FODMAP #gastroenterology #Hepatology #IrritableBowelSyndrome #MedicalSchool #medicine #Microbiome #Pain #research #Syndrome #Therapeutics #therapy
https://www.newsbeep.com/au/624229/

Cellular senescence is a biological stress response where cells cease dividing but do not die, instead lingering in tissue and emitting a toxic cocktail of inflammatory signals. In the liver, immune cells known as macrophages can enter this "zombie" state, continuously accumulating and driving the chronic inflammation associated with both aging and fatty liver disease.
#CellBiology #Immunology #Hepatology #Gerontology #MolecularBiology #sflorg
https://www.sflorg.com/2026/04/cbio04162602.html

https://www.europesays.com/ie/406315/ New algorithm enables precise subtyping of metabolic liver disease #CardiovascularDisease #Chronic #ChronicKidneyDisease #Cirrhosis #diabetes #DiabetesMellitus #Éire #fibrosis #Health #Hepatology #hospital #IE #Ireland #Kidney #KidneyDisease #Liver #LiverDisease #MedicalSchool #Research #Steatosis #Technology #Type2Diabetes

A common symptom of advanced cirrhosis is:
A. Joint pain
B. Yellowing of the skin (jaundice)
C. Vision loss
D. Hearing loss
#cirrhosis #liverhealth #hepatology #livercirrhosis ... Continue to: https://www.facebook.com/1130092409221646/posts/1257987026432183

A common symptom of advanced cirrhosis is:
A. Joint pain
B. Yellowing of the skin (jaundice)
C. Vision loss
D. Hearing loss
#cirrhosis #liverhealth #hepatology #livercirrhosis ... Continue to: https://www.facebook.com/1130092409221646/posts/1257987026432183

A common symptom of advanced cirrhosis is:
A. Joint pain
B. Yellowing of the skin (jaundice)
C. Vision loss
D. Hearing loss
#cirrhosis #liverhealth #hepatology #livercirrhosis ... Continue to: https://www.facebook.com/1130092409221646/posts/1257987026432183

GastroAGI is an AI-powered knowledge platform for gastroenterology & hepatology—built for clinicians, trainees, and researchers.

Evidence-first answers from journals, guidelines, and conferences. No noise. No hallucinations. Just clarity.

#GastroAGI #Gastroenterology #Hepatology #MedicalAI #EvidenceBasedMedicine #MedEd #ClinicalPractice #GIResearch

COBALT Trial (PBC): Despite early termination, adjusted analyses + real-world external controls showed obeticholic acid (OCA) reduces major liver events.

EC (External Control) analysis: 60% risk reduction in the risk of adverse clinical outcomes like death, liver transplantation, or hepatic decompensation.(HR 0.39).

Well-tolerated; pruritus most common.

Highlights power of hybrid RCT + real-world evidence.

#PBC #Hepatology #GastroAGI

Fatty degeneration of hepatocytes (fatty hepatosis) #hepatology #hepatocytes #liver #liverhealth ... Continue to: https://www.facebook.com/reel/25669765376050249/

Fatty degeneration of hepatocytes (fatty hepatosis) #hepatology #hepatocytes #liver #liverhealth ... Continue to: https://www.facebook.com/reel/25669765376050249/

Fatty degeneration of hepatocytes (fatty hepatosis) #hepatology #hepatocytes #liver #liverhealth ... Continue to: https://www.facebook.com/reel/25669765376050249/

🔬 GastroAGI — February 2026 Updates

February updates are live on GastroAGI, covering key areas in gastroenterology and hepatology, including Liver Transplantation, Endoscopy, IBD, GI Oncology, Upper GI disorders, Cirrhosis, and Fatty Liver Disease (MASLD).

Explore more: https://gastroagi.com

#Gastroenterology #Hepatology #MedEd #Endoscopy #IBD #MASLD

🔬 GastroAGI — February 2026 Updates

February updates are live on GastroAGI, covering key areas in gastroenterology and hepatology, including Liver Transplantation, Endoscopy, IBD, GI Oncology, Upper GI disorders, Cirrhosis, and Fatty Liver Disease (MASLD).

Explore more: https://gastroagi.com

#Gastroenterology #Hepatology #MedEd #Endoscopy #IBD #MASLD

https://www.europesays.com/ie/312647/ Dynamic viral markers predict treatment response in hepatitis B #Antigen #Chronic #Éire #HBV #Health #Hepatitis #HepatitisB #Hepatology #IE #Interferon #Ireland #Liver #Research #RNA

https://www.europesays.com/ie/199009/ Risk factors and prediction model development for pancreatic fistula following splenectomy in Wilson’s disease patients with portal hypertension | BMC Gastroenterology #Éire #Gastroenterology #Health #Hepatology #IE #InternalMedicine #Ireland

The HBsAg/HBV DNA ratio’s potential for predicting disease progression

Patients with chronic hepatitis B virus (HBV) infection in the immune-tolerant phase may still experience hepatic inflammation and…
#NewsBeep #News #Health #Antigen #AU #Australia #Chronic #dna #HBV #Hepatitis #HepatitisB #HepatitisBVirus #Hepatology #Inflammation #Liver #research #virus
https://www.newsbeep.com/au/86663/

Cruciferous vegetables intake and risk of colon cancer: a dose–response meta-analysis | BMC Gastroenterology

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates…
#NewsBeep #News #Technology #AU #Australia #ColonCancer #Cruciferousvegetables #gastroenterology #Hepatology #internalmedicine #meta-analysis #Systematicreview
https://www.newsbeep.com/au/59899/

A patient-based iPSC-derived hepatocyte model of alcohol-associated cirrhosis reveals bioenergetic insights into disease pathogenesis. https://doi.org/10.1038/s41467-024-47085-y #StemCellResearch #Hepatology #TranslationalResearch

The single worst #medical job I ever had involved no hands-on patient care at all.

Now, I experienced some very bad days as a #military #medic, and more as a #civilian #EMT. I worked on #ambulances, in #emergency #departments, and in safety net #clinics. I saw suffering on a scale I had never even imagined before. Of course I did my best to relieve that suffering—both because it was my job, and because I’m a decent human being—but a lot of the time I just couldn’t, and neither could anyone else. I celebrated my successes and mourned my failures. The memory of the former sustains me to this day, but the accumulation of the latter did lasting damage to the inside of my head. Practically anyone who’s ever been in the biz can say the same.

But all the #gunshots and car #crashes and #overdoses and #child #abuse cases and long, steady descents into the grave, over the course of years, didn’t burn me out like two months in a #cardiology practice.

You may wonder why. Okay, cardiology patients are generally pretty sick: you don’t get assigned a #cardiologist, rather than having your primary care provider take care of it, unless your #heart’s in bad shape. Even so, could it really be worse than all the above? After all, cardiology offices tend to be clean, well-lit, organized places. Patients have appointments. Fairly routine care, and if there’s really bad news, it’s the #physicians who have to give it—which is not the situation in #emergency #medicine, let me tell you.

Well, it did, and here’s the reason. Like I said, I wasn’t taking care of patients directly. My interaction with them was brief, in exam rooms after they’d already been checked in and seen by their providers, and I never touched them. It was all paperwork.

My job was to be their advocate with the #insurance companies. I did most of my work in an office, with a comfy chair and a phone and a coffee cup close at hand. The job was actually supposed to be an #RN position, but I impressed them enough at the interview to get it, and I got paid more for it than any other medical job I had before or since.

I read their #charts and #prescriptions, studied insurance claims, and—now we come to the crux of it—looked over the reasons those claims were denied. Sometimes very elaborate reasons, with lengthy justifications. Other times the feedback from the insurance companies was basically just “NO.”

And then I called those companies, and worked my way up through the phone tree until I got someone on the line with some actual decision-making authority, and explained to them in great detail why they should approve a particular medication or procedure that would keep our patients from dying.

I succeeded … maybe a quarter of the time? Probably less. Occasionally the failures weren’t complete: I couldn’t get them to approve whatever the cardiologist had recommended, but I could at least squeeze something out of them. Something that would keep our patients, the people entrusting us with their lives, going for a little while longer. Some sliver of hope for the patients and their families. Some human connection that reminded the people on the other end of the line that their job wasn’t actually to condemn people to death, at least not on paper.

Usually not. But often enough to keep me there for a little while. The nightmares stayed under control as long as I had a bottle waiting for me when I got home. Now that I think about it, that may have been when my drinking problem got serious, although it would take several more years to fully manifest. Good thing it wasn’t a #hepatology practice, I guess.

A friend’s post dredged this memory up. I was going to leave it as a comment there, but I didn’t want to make it all about me. They have enough of their own problems. Just know, if you’re fighting this particular war right now, I’m with you.

Oh yeah, also? #Vote. Specifically, if you can’t vote for someone who will make it better, at least vote for someone who won’t make it worse. Because it can always get worse.

In my spy role on acute medicine in last year of anaesthetic training for ICU, have noticed very difficult decision making on decompensated liver. New guidelines help #icm #criticalcare #hepatology #liverdisease

Interesting new paper in #Nature finds that #ClonalHematopoiesis mutations in the blood can contribute to #ChronicLiverDisease. The authors use a combination of human cohort data and mouse models to show that these mutations lead to more #inflammatory changes in the #liver. https://www.nature.com/articles/s41586-023-05857-4 #science #medicine #genomics #hematology #hepatology #LiverDisease

Interesting new paper in #Nature finds that #ClonalHematopoiesis mutations in the blood can contribute to #ChronicLiverDisease. The authors use a combination of human cohort data and mouse models to show that these mutations lead to more #inflammatory changes in the #liver. https://www.nature.com/articles/s41586-023-05857-4 #science #medicine #genomics #hematology #hepatology #LiverDisease

Interesting new paper in #Nature finds that #ClonalHematopoiesis mutations in the blood can contribute to #ChronicLiverDisease. The authors use a combination of human cohort data and mouse models to show that these mutations lead to more #inflammatory changes in the #liver. https://www.nature.com/articles/s41586-023-05857-4 #science #medicine #genomics #hematology #hepatology #LiverDisease

Interesting new paper in #Nature finds that #ClonalHematopoiesis mutations in the blood can contribute to #ChronicLiverDisease. The authors use a combination of human cohort data and mouse models to show that these mutations lead to more #inflammatory changes in the #liver. https://www.nature.com/articles/s41586-023-05857-4 #science #medicine #genomics #hematology #hepatology #LiverDisease

Interesting new paper in #Nature finds that #ClonalHematopoiesis mutations in the blood can contribute to #ChronicLiverDisease. The authors use a combination of human cohort data and mouse models to show that these mutations lead to more #inflammatory changes in the #liver. https://www.nature.com/articles/s41586-023-05857-4 #science #medicine #genomics #hematology #hepatology #LiverDisease