#mirna — Public Fediverse posts

#Grožnjan #Grisignana 🇭🇷 is one of these picturesque hilltop towns in #Istria. Beautiful morning lights as we visited earlier today. Views include #Motovun, high up above the #Mirna valley.

#Grožnjan #Grisignana 🇭🇷 is one of these picturesque hilltop towns in #Istria. Beautiful morning lights as we visited earlier today. Views include #Motovun, high up above the #Mirna valley.

Postdoctoral Fellow – RNA Biology and Cancer (miRNA Biogenesis)
National Cancer Institute, National Institutes of Health

Join our lab as a #postdoc to study #miRNA biogenesis and #cancer using CRISPR and prime editing to uncover RNA regulation mechanisms

See the full job description on jobRxiv: https://jobrxiv.org/job/national-canc...
https://jobrxiv.org/job/national-cancer-institute-national-institutes-of-health-27778-postdoctoral-fellow-rna-biology-and-cancer-mirna-biogenesis/?fsp_sid=12113

Postdoctoral Fellow – RNA Biology and Cancer (miRNA Biogenesis)
National Cancer Institute, National Institutes of Health

Join our lab as a #postdoc to study #miRNA biogenesis and #cancer using CRISPR and prime editing to uncover RNA regulation mechanisms

See the full job description on jobRxiv: https://jobrxiv.org/job/national-canc...
https://jobrxiv.org/job/national-cancer-institute-national-institutes-of-health-27778-postdoctoral-fellow-rna-biology-and-cancer-mirna-biogenesis/?fsp_sid=12113

Postdoctoral Fellow – RNA Biology and Cancer (miRNA Biogenesis)
National Cancer Institute, National Institutes of Health

Join our lab as a #postdoc to study #miRNA biogenesis and #cancer using CRISPR and prime editing to uncover RNA regulation mechanisms

See the full job description on jobRxiv: https://jobrxiv.org/job/national-canc...
https://jobrxiv.org/job/national-cancer-institute-national-institutes-of-health-27778-postdoctoral-fellow-rna-biology-and-cancer-mirna-biogenesis/?fsp_sid=11401

Postdoctoral Fellow – RNA Biology and Cancer (miRNA Biogenesis)
National Cancer Institute, National Institutes of Health

Join our lab as a #postdoc to study #miRNA biogenesis and #cancer using CRISPR and prime editing to uncover RNA regulation mechanisms

See the full job description on jobRxiv: https://jobrxiv.org/job/national-canc...
https://jobrxiv.org/job/national-cancer-institute-national-institutes-of-health-27778-postdoctoral-fellow-rna-biology-and-cancer-mirna-biogenesis/?fsp_sid=11401

#Istria 🇭🇷. Today, a hike around #Grožnjan #Grisignana, an area full of hilltop villages and churches, and olive groves. Views reach as far as #Motovun. As the sun sets, the fog forms, down in the #Mirna river valley.

#Istria 🇭🇷. Today, a hike around #Grožnjan #Grisignana, an area full of hilltop villages and churches, and olive groves. Views reach as far as #Motovun. As the sun sets, the fog forms, down in the #Mirna river valley.

In #Grožnjan #Grisignana #Istria 🇭🇷 today. A place high up above the #Mirna river valley, views towards #Motovun included.

In #Grožnjan #Grisignana #Istria 🇭🇷 today. A place high up above the #Mirna river valley, views towards #Motovun included.

RE: https://mastodon.social/@HafizHusnain/115328490796649616

This review connects molecular biology and clinical neuroscience, showing how #miRNAs could transform how we diagnose and treat neurodegenerative diseases.

#Neuroscience #Neurodegeneration #Biomarkers #miRNA #MolecularBiology #Alzheimers #Parkinsons #ALS #Huntingtons #biosensors #NGS #Diagnostics #Therapeutics #AcademicMastodon #OpenScience #springernature

🧬 Latest review article published today!
“MicroRNAs in neurodegenerative diseases: from molecular mechanisms to clinical biomarkers, detection methods and therapeutic strategies — advances and challenges.”

Discover how miRNAs, tiny regulators of gene expression, are transforming diagnostics & therapies for Alzheimer’s, Parkinson’s, ALS & Huntington’s disease.

🔗 Read: https://doi.org/10.1007/s10072-025-08419-w

https://doi.org/10.3389/fnmol.2024.1386735

#Neuroscience #miRNA #Neurodegeneration #Biomarkers #MolecularBiology #AD

TLDR: Pandas are dope fiends!?

TIL that 🐼 Pandas aren't born loving 🎍bamboo, but that it's an addiction with a dopamine component.

Those cute furry pandas are actually carnivores. 🍖

But they sit on their butts all day eating plants 🌿 and getting 🌀👃🌀 high instead of chasing animals. 🐁

Quote: "some of the bamboo-derived miRNAs were found to regulate dopamine pathways, driving food motivation and the reward system linked to it. So if eating bamboo is a pleasurable, satisfying experience for a panda, it's more likely to be solely driven to seek out this trigger." https://newatlas.com/biology/pandas-bamboo-micro-rna/

Pandas! :pandahype: :pandabighype:

#drugs #dopamine #pandas #bamboo #miRNA #RNA

TLDR: Pandas are dope fiends!?

TIL that 🐼 Pandas aren't born loving 🎍bamboo, but that it's an addiction with a dopamine component.

Those cute furry pandas are actually carnivores. 🍖

But they sit on their butts all day eating plants 🌿 and getting 🌀👃🌀 high instead of chasing animals. 🐁

Quote: "some of the bamboo-derived miRNAs were found to regulate dopamine pathways, driving food motivation and the reward system linked to it. So if eating bamboo is a pleasurable, satisfying experience for a panda, it's more likely to be solely driven to seek out this trigger." https://newatlas.com/biology/pandas-bamboo-micro-rna/

Pandas! :pandahype: :pandabighype:

#drugs #dopamine #pandas #bamboo #miRNA #RNA

Why don't #pandas eat more meat? #Molecules found in #bamboo may be behind their plant-based diet.

#miRNA #regulation #gene_expression #sensing #dopamine

https://phys.org/news/2025-02-dont-pandas-meat-molecules-bamboo.html

Why don't #pandas eat more meat? #Molecules found in #bamboo may be behind their plant-based diet.

#miRNA #regulation #gene_expression #sensing #dopamine

https://phys.org/news/2025-02-dont-pandas-meat-molecules-bamboo.html

To achieve this, we developed #DynamiR (https://codeberg.org/a_probst/DynamiR).

DynamiR a Python-based open-source tool with minimal dependencies, making it easy for anyone to analyze independently.

It's built on open data and decentralized, ensuring flexibility and adaptability.

#miRNA #NeurodegenerativeDiseases #ResearchUpdates #OpenScience #SoftwareDevelopment #PD #ALS #HD

research article [2019]

Pollen-derived RNAs Are Found in the Human Circulation
https://doi.org/10.1016/j.isci.2019.08.035

#pollen #microRNA #miRNA #bioavailability #platelets #Lungs #biology

Ich hab heute Spätschicht für euch gemacht, um (hoffentlich) schön aufzuschreiben, wie es zur Entdeckung von #miRNA kam und was hinter dem diesjährigen Med/Physio-#Nobelpreis steckt: #Wissen #Wissenschaft
https://www.spektrum.de/news/nobelpreis-fuer-physiologie-oder-medizin-2024-micrornas/2236046

Ich hab heute Spätschicht für euch gemacht, um (hoffentlich) schön aufzuschreiben, wie es zur Entdeckung von #miRNA kam und was hinter dem diesjährigen Med/Physio-#Nobelpreis steckt: #Wissen #Wissenschaft
https://www.spektrum.de/news/nobelpreis-fuer-physiologie-oder-medizin-2024-micrornas/2236046

2024 Nobel Prize in Medicine for discovery of "microRNA and new Principle of Gene regulation"
The 2024 Nobel Prize in Physiology or Medicine has been awarded jointly to Victor Ambros and Gary Ruvkun “for the discovery of microRNA and its role...........
#GaryRuvkun #generegulation #microRNA #miRNA #Nobelprize #NobelprizeinMedicine #RNA #transcription #VictorAmbros
Rajeev Soni

https://www.scientificeuropean.co.uk/sciences/biology/2024-nobel-prize-in-medicine-for-discovery-of-microrna/

2024 Nobel Prize in Medicine for discovery of "microRNA and new Principle of Gene regulation"
The 2024 Nobel Prize in Physiology or Medicine has been awarded jointly to Victor Ambros and Gary Ruvkun “for the discovery of microRNA and its role...........
#GaryRuvkun #generegulation #microRNA #miRNA #Nobelprize #NobelprizeinMedicine #RNA #transcription #VictorAmbros
Rajeev Soni

https://www.scientificeuropean.co.uk/sciences/biology/2024-nobel-prize-in-medicine-for-discovery-of-microrna/

Today #Nobel Assembly of #Karolinska Institutet has recognized the work of 71 yo Victor Ambros and 72 yo Gary Ruvkun aimed at proving existence of #miRNA
-micro RNA- and its importance in🧬#Gene regulation
with 2024 #NobelPrize in #Physiology or #Medicine
Something about this follows

Role of #miRNA in Highly Pathogenic #H5 Avian #Influenza Virus #Infection: An Emphasis on Cellular and #Chicken #Models, Viruses: https://www.mdpi.com/1999-4915/16/7/1102

Current research indicates that miRNAs play a significant role in HPAI H5 infections, influencing various aspects of the disease process. This review aims to synthesize recent findings on the impact of different miRNAs on immune function, viral cytopathogenicity, and respiratory viral replication.

Role of #miRNA in Highly Pathogenic #H5 Avian #Influenza Virus #Infection: An Emphasis on Cellular and #Chicken #Models, Viruses: https://www.mdpi.com/1999-4915/16/7/1102

Current research indicates that miRNAs play a significant role in HPAI H5 infections, influencing various aspects of the disease process. This review aims to synthesize recent findings on the impact of different miRNAs on immune function, viral cytopathogenicity, and respiratory viral replication.

Improving #plant health diagnostics: The dawn of #microfluidic devices for rapid #miRNA detection.

#miR399 #phosphate #nutrition

https://phys.org/news/2024-03-health-diagnostics-dawn-microfluidic-devices.html

Come work with us! I have a PhD position available to help understand which mutations in the non-coding parts of coding transcripts have functional consequences in Stem Cells.

We will using genome wide mesaurement of the effect of variation in miRNA binding sites to address when vairation causes changes in regulation and when it doesn't.

Mixed wetlab, bioinformatics and statistics project.

https://www.findaphd.com/phds/project/white-rose-bbsrc-dtp-how-can-we-identify-variants-in-untranslated-rna-that-affect-stem-cells/?p160958

#phdPosition #PhD #bioinformatics #UTR #miRNA #genetics

Come work with us! I have a PhD position available to help understand which mutations in the non-coding parts of coding transcripts have functional consequences in Stem Cells.

We will using genome wide mesaurement of the effect of variation in miRNA binding sites to address when vairation causes changes in regulation and when it doesn't.

Mixed wetlab, bioinformatics and statistics project.

https://www.findaphd.com/phds/project/white-rose-bbsrc-dtp-how-can-we-identify-variants-in-untranslated-rna-that-affect-stem-cells/?p160958

#phdPosition #PhD #bioinformatics #UTR #miRNA #genetics

Deregulated miRNA Expression in Triple-Negative Breast Cancer of Ancestral Genomic-Characterized Latina Patients. https://doi.org/10.3390/ijms241713046 #TripleNegativeBreastCancer #Latinas #CopyNumberAlterations #Microrna #Mirna

Deregulated miRNA Expression in Triple-Negative Breast Cancer of Ancestral Genomic-Characterized Latina Patients. https://doi.org/10.3390/ijms241713046 #TripleNegativeBreastCancer #Latinas #CopyNumberAlterations #Microrna #Mirna

Potential of miRNAs in Plasma Extracellular Vesicle for the Stratification of Prostate Cancer in a South African Population. https://doi.org/10.3390/cancers15153968 #ProstateCancer #ExtracellularVesicles #Exosomes #Mirna #Mir1945p

Potential of miRNAs in Plasma Extracellular Vesicle for the Stratification of Prostate Cancer in a South African Population. https://doi.org/10.3390/cancers15153968 #ProstateCancer #ExtracellularVesicles #Exosomes #Mirna #Mir1945p

Had a lovely time talking about our work on #miRNA and #glycans #glycotime at U of Toronto Chem. Thank you Mark Nitz for hosting!

Had a lovely time talking about our work on #miRNA and #glycans #glycotime at U of Toronto Chem. Thank you Mark Nitz for hosting!

Heat shock during #Drosophila #embryogenesis results in maternal miRNA retention & downregulation of pre-MBT genes including Elba1, which may contribute to setting the stage for subsequent gene expression ➡️ https://www.embopress.org/doi/full/10.15252/msb.202211148
from Anita Öst, Linköping University #miRNA #GeneRegulation #SystemsBiology

Heat shock during #Drosophila #embryogenesis results in maternal miRNA retention & downregulation of pre-MBT genes including Elba1, which may contribute to setting the stage for subsequent gene expression ➡️ https://www.embopress.org/doi/full/10.15252/msb.202211148
from Anita Öst, Linköping University #miRNA #GeneRegulation #SystemsBiology

DICER is one of the fundamental enzymes in your body, responsible for processing RNA into different forms, often involved with RNA silencing.

While we know how double stranded RNAs are processed, how DICER processes microRNAs is poorly understood.

Now, Seoul National University scientists have identified how it utilizes the GYM motif for processing, expanding our fundamental understanding.

#Biology #Microbiology #Genetics #RNA #Dicer #miRNA #Science #Scicomm

https://www.nature.com/articles/s41586-023-05723-3

DICER is one of the fundamental enzymes in your body, responsible for processing RNA into different forms, often involved with RNA silencing.

While we know how double stranded RNAs are processed, how DICER processes microRNAs is poorly understood.

Now, Seoul National University scientists have identified how it utilizes the GYM motif for processing, expanding our fundamental understanding.

#Biology #Microbiology #Genetics #RNA #Dicer #miRNA #Science #Scicomm

https://www.nature.com/articles/s41586-023-05723-3

Business-Academic Team to Create RNA Delivery for Cancer

A #university lab and #biotechnology company are developing new #cancer treatments with therapies that stop #RNA activity, delivered by advanced #nanoscale particles.

https://sciencebusiness.technewslit.com/?p=44505

#News #Science #Business #Chemistry #Collaboration #Licensing #Pharmacology #PancreaticCancer #Preclinical #miRNA #Silicon #UK #Germany

@clathrin I know it is self promoting , but I really think our finding that upregulation of protein expression via direct interactions between microRNA and mRNA in cancer cells is one of the coolest of my career and opens a lot of doors. Bonus, the paper is open access. #RNA #miRNA

https://pubs.acs.org/doi/10.1021/acscentsci.2c00748

Just Published!

"Epigenetic Regulation of Cancer by Natural Touch: Phytochemicals and Epigenetic Regulation"

https://link.springer.com/chapter/10.1007/16833_2022_44

#Cancer #CancerResearch #Epigenetics #miRNA