#sysreview — Public Fediverse posts

A #SysReview exploring impacts of community-based interventions for adults with #multimorbidity on clinical and patient-reported outcomes (25 studies):
https://bmjpublichealth.bmj.com/content/4/1/e004156

Quick comparison of identified outcomes with the two central #CoreOutcomeSets 👇

#HRQOL #Psychometrics #PatientCentered

Quality Assessment of Diagnostic Test Accuracy Studies

QUADAS-3 published:
https://pubmed.ncbi.nlm.nih.gov/41698208/

__Key changes from QUADAS-2__

introduction of an 'ideal test accuracy trial'

assessment at the estimate rather than study level

"Flow and Timing" domain replaced with an "Analysis" domain

sections on the rationale for judgments

introduction of a judgment of #RiskOfBias and concerns regarding applicability

#Psychometrics #SysReview #RoB

Busy week, I have not much posted from #RSS2025. This will follow in the next days.

For now, I enjoyed chatting with Robert Grant and am reading his co-authored book "Bayesian #MetaAnalysis" which he kindly gave me a copy of 🙇
http://www.robertgrantstats.co.uk/bma-book.html

I am always looking combinations of unusual and cross-cutting themes for teaching/ training, so I'll do a parallel read with #MixtureModels in this area: https://link.springer.com/chapter/10.1007/978-3-540-68651-4_7

#SysReview #SystematicReview #Bayes

A #SysReview of quality of life and #HRQoL instruments used in trials of interventions for adults with alcohol use disorder:
https://www.jsatjournal.com/article/S2949-8759(25)00172-9/fulltext

One of the interesting findings:
Although the team focused on the most frequently used instruments they found only very few studies reporting psychometric properties in this population.

This mirrors findings from our broader #SysReview of #HRQL as an outcome in substance and behavioural addictions
https://pubmed.ncbi.nlm.nih.gov/37439397/

#Psychometrics #Validity

A #SysReview (24 studies) synthesises evidence around the impact of adopting different perspectives when valuing child & adolescent #HRQL
https://link.springer.com/article/10.1007/s40273-025-01493-0

Results show that differences in mean values arise with different perspectives on severe child #HealthStates. These differences are influenced by factors such as health state severity and valuation method. Uncertainty remains regarding the optimal choice of preference elicitation and anchoring methods.

#HealthEconomics

Core outcome sets for trials of interventions to prevent and to treat #multimorbidity in adults in low and middle-income countries
https://gh.bmj.com/content/9/8/e015120.info

In the works since early 2020 w #SysReview, 50 qualitative interviews in 10 countries, Delphi study & consensus meetings.

Enormous thanks to all who made this possible!🙇

Summary of core outcomes 👇 incl. earlier seminal #COSmm work in #HIC.

#GlobalHealth #Multimorbidity #HRQL #LMIC

Core outcome sets for trials of interventions to prevent and to treat #multimorbidity in adults in low and middle-income countries
https://gh.bmj.com/content/9/8/e015120.info

In the works since early 2020 w #SysReview, 50 qualitative interviews in 10 countries, Delphi study & consensus meetings.

Enormous thanks to all who made this possible!🙇

Summary of core outcomes 👇 incl. earlier seminal #COSmm work in #HIC.

#GlobalHealth #Multimorbidity #HRQL #LMIC

Core outcome sets for trials of interventions to prevent and to treat #multimorbidity in adults in low and middle-income countries
https://gh.bmj.com/content/9/8/e015120.info

In the works since early 2020 w #SysReview, 50 qualitative interviews in 10 countries, Delphi study & consensus meetings.

Enormous thanks to all who made this possible!🙇

Summary of core outcomes 👇 incl. earlier seminal #COSmm work in #HIC.

#GlobalHealth #Multimorbidity #HRQL #LMIC

Core outcome sets for trials of interventions to prevent and to treat #multimorbidity in adults in low and middle-income countries
https://gh.bmj.com/content/9/8/e015120.info

In the works since early 2020 w #SysReview, 50 qualitative interviews in 10 countries, Delphi study & consensus meetings.

Enormous thanks to all who made this possible!🙇

Summary of core outcomes 👇 incl. earlier seminal #COSmm work in #HIC.

#GlobalHealth #Multimorbidity #HRQL #LMIC

Quality of Life Research 03-2024
https://link.springer.com/journal/11136/volumes-and-issues/33-3, incl.

A #SysReview of #HRQL in emergency laparotomy #RCTs
https://link.springer.com/article/10.1007/s11136-023-03531-w

comparison of @promisNIH 29/global physical and #MentalHealth scores
https://link.springer.com/article/10.1007/s11136-023-03559-y

and using unsupervised IRT models for assessing sample heterogeneity
https://link.springer.com/article/10.1007/s11136-023-03560-5
#Psychometrics

You would like to engage with #ISOQOL conference content?

How about reading the 2022 article of the year finalists?

1) Association btw 24h movement behaviors and #HRQL in children
rdcu.be/dpqJY
#Winner 🎉

2) Perceived benefits and limitations of using patient‑reported outcome measures in clinical practice with individual patients
rdcu.be/dpqKK
#Feedback #SysReview

3) #SocialSupport and HRQL among the oldest old
https://link.springer.com/article/10.1007/s11136-021-03070-2
#AgeQualiDe

In #ISOQOL-s #QualityTALK, Carolyn Schwartz provides an insight into her development as a researcher
https://www.isoqol.org/the-story-behind-the-elephant-in-the-room-a-long-journey-begins-with-a-single-step/

Reflecting on research experiences with people living with Multiple Sclerosis, she realised that what was important to patients did not form a consistent hierarchy of domains for each patient over time. This led her into #ResponseShift research and she discusses her most recent #SysReview on the importance of the phenomenon in #RCTs #Trials:
https://jpro.springeropen.com/articles/10.1186/s41687-022-00510-6

Last week "Quality of Life Research" published 6 papers:
https://link.springer.com/journal/11136/online-first #ISOQOL

For example,

A #SysReview showing widespread use of #PreferenceBased measures in studies w Indigenous people, but little evidence on their measurement properties
https://link.springer.com/article/10.1007/s11136-023-03499-7 #EQ5D

A comparative assessment of such measures in China
https://link.springer.com/article/10.1007/s11136-023-03512-z

And the elicitation of a #ValueSet for the Swedish Capability-Adjusted Life Years instrument
https://link.springer.com/article/10.1007/s11136-023-03507-w #TTO

#HealthEconomics

Last week "Quality of Life Research" published 7 papers:
https://link.springer.com/journal/11136/online-first #ISOQOL

For example,

effectiveness of verbal instruction vs video-based education for caregivers of head & neck #cancer patients
https://rdcu.be/diEFn
#India #PalliativeCare

#SysReview of psychometric quality of instruments reporting #HRQL in survivors of critical illness
https://link.springer.com/article/10.1007/s11136-023-03487-x #COSMIN

Estimating the disutility of relapse in #MultipleSclerosis
https://link.springer.com/article/10.1007/s11136-023-03486-y #EQ5D #AQoL #SF6D

What can #psychometrics offer for #CrossCultural research? Why is simply translating questionnaires rarely enough for international research efforts?

#SysReview published last week excellently illustrates the #interdisciplinary problems:
https://onlinelibrary.wiley.com/doi/full/10.1111/dar.13715 measuring #AlcoholUse

Two other examples I like a lot:
https://pubmed.ncbi.nlm.nih.gov/26319270/ in #Dementia
and
https://www.pnas.org/doi/10.1073/pnas.1721166115 for broader #BehaviouralScience issues.

#TranslationIsNotEnough #HRQL #GlobalHealth #GlobalMentalHealth

Quality of Life Research, July issue published:
https://link.springer.com/journal/11136/volumes-and-issues/32-7
#ISOQOL #HRQL

Opened by a #SysReview of instruments measuring the quality of dying and death in Asian countries:
https://rdcu.be/ddRIE
#COSMIN #EndOfLifeCare

the issue features several pieces on properties of various instruments in different contexts and versions, e.g.,

#EQ5D
https://link.springer.com/article/10.1007/s11136-023-03372-7

#EORTC https://link.springer.com/article/10.1007/s11136-023-03373-6

#PROCTCAE
https://link.springer.com/article/10.1007/s11136-023-03374-5