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  1. The NCBI nr FASTA file of protein sequences is no longer updated. We've summarised instructions for creating it from the BLAST database -- or you may be better off using TrEMBL.

    matrixscience.com/blog/replace

    #proteomics #massspec

  2. Mascot Newsletter, October 2025:

    Spectrum-centric DIA scoring.

    Molecular mechanisms of SBK2 kinase on the heart.

    Windows update issue with IIS (resolved).

    matrixscience.com/nl/202510/ne

    #proteomics #massspec

  3. Mascot Daemon can export protein level quant intensities for replicate LFQ, SILAC and iTRAQ/TMT. The latest version can also export intensity values calculated using the "Top-3" method, illustrated here with DDA-PASEF data.

    matrixscience.com/blog/top-3-q

    #proteomics #massspec

  4. We are pleased to announce a new distributor for Matrix Science products! Customers in India can now buy Mascot Server through BioInnovations, who provide instruments, software, services and consumables for life sciences and analytical and clinical labs. #proteomics #massspec

    matrixscience.com/whats_new/ne

  5. Probabilistic scoring of DIA matches without spectral deconvolution? Not only is it possible, we're working on implementing it in Mascot DIA.

    matrixscience.com/blog/probabi

    #proteomics #massspec

  6. Mascot Newsletter, August 2025:

    Precursor detection for spectrum-centric DIA.

    Reconstructing mediaeval monastic diets.

    Microsoft has announced the end of Windows 10 support; your Mascot Server may be affected.

    matrixscience.com/nl/202508/ne

    #proteomics #massspec

  7. I've been exploring linux stuff today and setting up irc before I start editting on shorts again, and I just found out thunderbird supports chatting via irc, xmpp (Jabber), and freaking matrix...

    I need to know who's using thunderbird to chat on matrix servers lol.

    #matrix #thunderbird

  8. CW: Deltarune ch2, Matrix

    *unable to decrypt* is literally Matrix' version of Spamtom's [HYPRLINK BLOCKED]

    #matrix #deltarune #spamton #unabletodecrypt #spamtongspamton

  9. @hopidd Entschuldigt die späte Antwort: Momentan ist alles in fester Hand von #Zoom, alternativ nicht weniger proprietär #AdobeConnect und #DFNConf. Die box.hu-berlin.de (#Seafile Pro) ist wenigstens clientseitig #FLOSS. #gnuHU hat die [Arbeitsgruppe Dezentrale Dienste](hu.berlin/agdd) als kleines gallisches Dorf gegründet (#Jitsi #Mumble). #BigBlueButton und #Matrix sind zumindest als offizielle HU-Dienste geplant, produktiv genutzt werden sie aber zum Semesterstart noch nicht.

  10. This month in my newsletter:

    New writing about 50 years of street performing at Covent garden, and how a computer incorrectly predicted my future life when I was a kid, along with photography, videos and other stuff!

    Hope you love it

    #substack #writer #blogger #newsletter #streetperforming #jiigcal #essay

    matricardo.substack.com/p/you-

  11. Matratze auf die #Terrasse und mit #Hund Jimmy in der #Sonne chillen. Habe von Ende August bis letzten Montag mit #WW (und viel Bewegung) 20 kg abgenommen, aber die man boobs zeigen schlimm, dass wohl eher 14 als 6 kg noch wegmüssen. Liebste Grüße aus dem #Remstal ins #Fediverse. :blobcatflower:

  12. Another passion of mine is the history of #Çatalhöyük site - and whether or not it had a #MatriachalSociety!

    Ancient city possibly ruled by females living in a "matriarchal society" more than 9,000 years ago, researchers say

    By Cara Tabachnick
    June 28, 2025

    Excerpt: "We need to move away from our Western bias that assumes all societies are #patrilineal. Many cultures, including some #IndigenousAustralian groups, pass identity, land rights, and responsibilities through the mother's line — a #matrilineal system,' study co-author Dr. Eline Schotsmans, a research fellow at Australia's University of Wollongong's School of Science, said in a statement.

    "These findings come several months after researchers studying social networks in #CelticSociety in Britain before the #RomanInvasion gathered genetic evidence from a late Iron Age cemetery and found that women were closely related, while unrelated men tended to come into the community from elsewhere, likely after marriage.

    "Using an examination of ancient DNA recovered from 57 graves in #Dorset in southwest England, their study, published in the journal Nature, shows that two-thirds of the individuals were descended from a single maternal lineage. This suggests that women had some control of land and property, as well as strong social support, researchers said.

    "Researchers said upon the release of their findings, 'It is possible that maternal ancestry was the primary shaper of group identities.' "

    Read more:
    cbsnews.com/news/ancient-city-

    Original paper:
    science.org/doi/10.1126/scienc

    #History #Histodon #Matrilineal #Matriarchy #AncientHistory #AncientTurkey #Neolithic #Anatolia #MotherGoddess

  13. Ok, ich bin jetzt seit etlichen Stunden damit beschäftigt #Matrix #Synapse dazu zu bringen #ElementCall zu verwenden... oida, ist das Setup ein scheiß.

    Zuvor wurde einfach ein Turn Server mit WebRTC verwendet für Anrufe. Turn Server sind ein Ding für sich, aber irgendwie bekommt man es ja dann doch hin. Doch #ElementX besteht darauf Element Call zu verwenden. Das sind dann zwei weitere Docker Container die laufen müssen, die Nginx Konfiguration muss man umwerfen und anpassen und und und.

    Die Entwickler von Synapse sollten langsam lernen ein vernünftiges Setup für Matrix zu ermöglichen. Ich verstehe durchaus, warum sich einige Admins den Mist nicht antun wollen. Man findet zwar alle Infos die man braucht in der Dokumentation, doch bis man die Infos wie Klemmbausteine zusammengesetzt hat, kostet dich das einige Nerven. Man hat 20 Tabs offen für so ziemlich alles was man beachten muss.

    Ich habe es bis jetzt zumindestens hinbekommen, dass ElementX weiß, dass man irgendwie anrufen kann. Ob die Anrufe funktionieren, wird sich morgen rausstellen, wenn jemand die auch entgegen nehmen kann.

    #Admin #Selfhosting

  14. Nice. Built my first working instance of Element Call. Everything running on our own servers and under our control, and true end-to-end encryption. Eat that, Zoom!

    It's only a test setup for now, but I foresee that Element Call will quickly become the main tool for videoconferencing, not only here but in many ICT environments.

    If you have no idea what I mean, visit the public instance and play with it:

    call.element.io/

    #Matrix #ElementCall

  15. Does anyone know if there's a way to search for #Matrix servers, or search for rooms across multiple servers?

    Or... does anyone know if a #naturist or #nudist Matrix server, space or room exists? There's #ElementCall coming out soon which would allow for video chat rooms, ala Zoom or Discord.

  16. Wondering if you can run @matrix and @xmpp on the same domain (same subdomain) - same hosting, or not - connected with a bridge bot, connecting your personal user on both.
    #matrix #xmpp #jabber #chat #integration #compatibility #networked #federation

    Have you tried?
    @nitrokey
    @monocles
    @chapril
    @mailbox_org

  17. 📚🔢 Ah, yet another thrilling bedtime story about matrix calculus—because who doesn't want to dive into a sea of math symbols with more enthusiasm than a toddler in a ball pit? 🙄 With authors who remind us that they have credentials longer than the paper itself, this is basically "Matrix Calculus for Dummies" but with extra academic snooze. 💤
    explained.ai/matrix-calculus/ #matrixcalculus #bedtimefun #mathhumor #academicwriting #dummiesguide #HackerNews #ngated

  18. 📚🔢 Ah, yet another thrilling bedtime story about matrix calculus—because who doesn't want to dive into a sea of math symbols with more enthusiasm than a toddler in a ball pit? 🙄 With authors who remind us that they have credentials longer than the paper itself, this is basically "Matrix Calculus for Dummies" but with extra academic snooze. 💤
    explained.ai/matrix-calculus/ #matrixcalculus #bedtimefun #mathhumor #academicwriting #dummiesguide #HackerNews #ngated

  19. 📚🔢 Ah, yet another thrilling bedtime story about matrix calculus—because who doesn't want to dive into a sea of math symbols with more enthusiasm than a toddler in a ball pit? 🙄 With authors who remind us that they have credentials longer than the paper itself, this is basically "Matrix Calculus for Dummies" but with extra academic snooze. 💤
    explained.ai/matrix-calculus/ #matrixcalculus #bedtimefun #mathhumor #academicwriting #dummiesguide #HackerNews #ngated

  20. financemetrics.scienceontheweb Maximising the value of a portfolio. Calculating #Variance, #CoVariance and portfolio Variance using the magic of Matrix Algebra. Calculations feature 5 ftse stocks, BP, Vodafone, UU.L, Tesco and Morrison. Detailed exposition leads one through x transpose multiplied b x. #MatrixAlgebra

  21. Сплиттеры для проектирования видеостен. Обзор на модели брендов PC Vision и Matrox

    В этой статье мы расскажем об основных технических особенностях и преимуществах видеосплиттеров для проектирования видеостен. Среди всего многообразия видеоконтроллеров, представленных на рынке, мы остановили свой выбор на двух брендах, способных составить достойную конкуренцию, - PC Vision и Matrox. Также мы рассмотрим их применение в различных конфигурациях и разрешениях.

    habr.com/ru/articles/973164/

    #видеостена #сплиттер #видеоконтроллер #matrox

  22. My #Matrox MGA Millennium has a serial number of 0041. That's... very low. 😲

    Btw, it has the "IS-STORM" chip, not the later MGA-2064W.

    #RetroComputing

  23. Can someone tell me why so many people and websites claim that the #Matrox MGA #Millennium does not support texture mapping? That's complete bullsh*t. It does, even the official promo video (here: youtube.com/watch?v=w76yFJ2zJy) tells that it supports texture mapping in hardware. And how do these people even think the 3d-accelerated version of NASCAR Racing works on the card? The game is fully texture-mapped...

    Anyway, unlike the earlier Impression (Plus), the Millennium does support texture mapping.

    #RetroComputing #RetroGaming

  24. Announces LUMA Graphics Cards Powered By Intel Arc Graphics

    phoronix.com/news/Matrox-Intel

  25. @lee4hmz I learned how to use CVS so I could check out Carmack's latest #matrox G200 enhancements every day.

  26. @d1 @daniel Second that. Quality and UX are way more important than features. See for how not to do it. I consider some lovely cuteness as part of UX, not an extra feature. See and @tootapp for how to do it.

  27. Matrix使用入门基础——用户向 :blob_dance:

    理念

    所有的一切都是开源的、免费的

    本文以我自建的服务器Homeserver为例,URL为: https://chat.feddit.social ,fork版本为matrix-synapse

    Matrix普遍用于去中心化,端到端加密聊天,可以通过自建维护Matrix实例,

    Matrix的权限管理十分详细,

    在Matrix上,你可以

    • 和本服务器的用户 聊天
    • 和在本服务器的聊天室的用户 聊天
    • 和其他Matrix系服务器的用户 聊天
    • 和在其他服务器的聊天室的用户 聊天

    注册

    注册需要一个非零时邮件(为了找回密码),然后通过邮件激活账户

    考虑方便程度,在此使用Cinny Web端

    Fluffychat Web端没有注册功能,Element Web端访问不稳定

    登录

    注意!
    自建的Matrix不提供聊天前端,代表不能和Mastodon一样,在上面注册登录发帖等,Matrix的注册、登录、聊天都需要依靠第三方客户端!

    登录可以有多种方法,一定要记住把matrix.org换成chat.feddit.social(或者其他)

    • 在PC上,推荐使用浏览器访问:https://app.cinny.in/login/chat.feddit.social

    • 在Mobile上,推荐使用FluffyChat APP网页版,Cinny网页版

      个人来说不推荐任何Matrix"官方"的App或者Web客户端,比如Element、ElementX

      更多客户端可以在此寻找: https://matrix.org/ecosystem/clients (需要翻墙)

    当你在另外一个客户端(App、Web)登录,会提示你需要验证客户端,这时候,你需要同时在两个客户端完成验证。

    一般来说,在新客户端登录,为了安全是不会有个人聊天记录(群组另算,看具体设置)

    如果登录后想要显示之前的聊天记录,需要在Setting打开Chat Backup,然后保存Es开头的恢复密钥!所以:

    • 一定要好好保管恢复密钥
    • 一定要记住恢复密钥保存的位置

    下一次在新的客户端登录,就可以选择填写此恢复密钥恢复聊天记录

    群组配置

    我重新更新了配置,使你可以公开你创建的房间"Publish to Directory",便于感兴趣的人加入

    目前:

    • Fluffy Chat(App、Web)不支持,只能搜索

    • Cinny(App、Web,Cinny App 只有PC版)支持此功能,即explore群组

    Matrix的设计逻辑:主要分为用户,群组,空间、子空间

    1. 用户之间的聊天独立

    2. 空间包括群组和子空间、子空间内不仅可以创建群组,而且还能创建"子子空间"...子子孙孙无穷匮也

    提醒:

    • 如果不是特别敏感的聊天,不建议开启"Room Encryption",没有好好的配置前提下,会让你的多端聊天变得破败,而且此操作不能被取消!

    就写到这里来,很多东西还是需要实际操作,学习起来更快

    下期记录自己搭建Matrix-Synapse Homeserver

    多次搭建过Matrix-Homeserver、本服务器已平稳运行2025.10.4——今日,可通过访问 https://chat.feddit.social/_matrix/static 确认服务区情况,也可以之间在Fediverse私信/回复我。

    @worldboard @board
    #matrix #matrix_synapse #linux #opensource #fluffychat #cinny #chat #聊天 #社区 #community #selfhost #selfhosting

  28. CW: Thoughts on Matrix, XMPP, and reliability

    As it turns out, I still can’t exactly recommend XMPP as a communication platform. I know a lot of people here on the Fediverse like and even prefer it to other platforms like Matrix, but it just doesn’t work reliably for me. Not years ago and not now. :gutkato_disokula:

    I just opened the XMPP client on my other device, navigated to a public room (group chat) I’m a part of, and the last three days’ worth of messages didn’t show up. Why? I don’t know. :gutkato_averto:

    This room’s information says it should be ‘Persistent’ and ‘Archiving’. Maybe the messages are archived, but not shared to all of the room members’ devices. Maybe the room needs an extra setting to do that. Or maybe it already does that, but only if the client and the server both support XMPP Extension number 4,872 (Self-Propagating Persistent Messages, version 2). :gutkato_ŝultrumas:

    It could just be this one room. It could be that the there are better clients that would inform me about this missing feature, but this one doesn’t. But as it stands, I apparently can’t just use XMPP and trust I’ll get to see the messages people sent me. With Matrix, I can. Sure, there might be a problem with encryption, but at least I’ll know someone tried to say something. :gutkato_ĝengrimacas:

    #lang_en #chat #free_software #Matrix #messaging #software #XMPP