#spillover — Public Fediverse posts

#Species - and #variant - specific #ACE2 compatibility shapes #SARS-CoV-2 #spillover potential in North American #cervids, https://etidiohnew.blogspot.com/2026/04/species-and-variant-specific-ace2.html

#Species - and #variant - specific #ACE2 compatibility shapes #SARS-CoV-2 #spillover potential in North American #cervids, https://etidiohnew.blogspot.com/2026/04/species-and-variant-specific-ace2.html

#Species - and #variant - specific #ACE2 compatibility shapes #SARS-CoV-2 #spillover potential in North American #cervids, https://etidiohnew.blogspot.com/2026/04/species-and-variant-specific-ace2.html

#Species - and #variant - specific #ACE2 compatibility shapes #SARS-CoV-2 #spillover potential in North American #cervids, https://etidiohnew.blogspot.com/2026/04/species-and-variant-specific-ace2.html

#Species - and #variant - specific #ACE2 compatibility shapes #SARS-CoV-2 #spillover potential in North American #cervids, https://etidiohnew.blogspot.com/2026/04/species-and-variant-specific-ace2.html

Pathogen host-jumps pose major risks to health, but how can we predict them? This study shows that #pathogen novelty, rather than #spillover rate, is a stronger predictor of host-jump risk, so we should monitor emerging pathogens with limited spillover histories @PLOSBiology https://plos.io/4ss5WCY

Spatiotemporal #clustering of highly pathogenic avian #influenza (HPAI) #H5N1 at the wild #waterfowl - #poultry interface: Vector-specific #spillover risks in the #US, 2022–2025, https://etidiohnew.blogspot.com/2026/03/spatiotemporal-clustering-of-highly.html

#MERS #Coronavirus–Specific T-Cell Responses in Dromedary #Camel #Abattoir #Workers in #Nigeria Suggests Frequent Zoonotic #Spillover, https://etidiohnew.blogspot.com/2026/03/mers-coronavirusspecific-t-cell.html

From #Surfaces to #Spillover: Environmental #Persistence and Indirect #Transmission of #Influenza #H3N8 Virus, https://etidiohnew.blogspot.com/2025/12/from-surfaces-to-spillover.html

Opportunity Drives #Spillover: Serological #Surveillance across #Carnivores, #Omnivores and #Herbivores in an #HPAIV #H5 Hotspot in North-East #Germany, 2023-2025, https://etidiohnew.blogspot.com/2025/10/opportunity-drives-spillover.html

Opportunity Drives #Spillover: Serological #Surveillance across #Carnivores, #Omnivores and #Herbivores in an #HPAIV #H5 Hotspot in North-East #Germany, 2023-2025, https://etidiohnew.blogspot.com/2025/10/opportunity-drives-spillover.html

Opportunity Drives #Spillover: Serological #Surveillance across #Carnivores, #Omnivores and #Herbivores in an #HPAIV #H5 Hotspot in North-East #Germany, 2023-2025, https://etidiohnew.blogspot.com/2025/10/opportunity-drives-spillover.html

Opportunity Drives #Spillover: Serological #Surveillance across #Carnivores, #Omnivores and #Herbivores in an #HPAIV #H5 Hotspot in North-East #Germany, 2023-2025, https://etidiohnew.blogspot.com/2025/10/opportunity-drives-spillover.html

Opportunity Drives #Spillover: Serological #Surveillance across #Carnivores, #Omnivores and #Herbivores in an #HPAIV #H5 Hotspot in North-East #Germany, 2023-2025, https://etidiohnew.blogspot.com/2025/10/opportunity-drives-spillover.html

Circulation and #Spillover of #H1N1pdm09 #Influenza A Virus at an Educational #Swine #Farm in #Chile, 2019–2023, https://etidiohnew.blogspot.com/2025/04/circulation-and-spillover-of-h1n1pdm09.html

Interessant, dass Christian #Drosten seine Meinung zum Ursprung von #Covid19 geändert hat.

Anfang 2020 hatte er noch gutgläubig die chinesischen Wissenschaftler:innen in Schutz genommen (hatte sich einem Statement in #TheLancet angeschlossen):
"We stand together to strongly condemn conspiracy theories suggesting that COVID-19 does not have a natural origin."

#LaborThese #LaborUnfall #Wuhan #Covid #Corona #zoonose #spillover #verschwörungstheorie
https://youtu.be/ipBvHhAIZfU?t=5298

A novel reassorted #swine #H3N2 #influenza virus demonstrates an undetected #human-to-swine #spillover in Latin #America and highlights zoonotic risks, https://etidiohnew.blogspot.com/2025/03/a-novel-reassorted-swine-h3n2-influenza.html

Newfound #bat #virus that uses notorious #receptor poses ‘#spillover’ #risk, https://www.nature.com/articles/d41586-025-00503-7

The virus is related to the #pathogen that causes #MERS and capitalizes on the same ‘entry receptor’ used by #SARS-CoV-2.

{#USA, #Nevada} The Occurrence of Another Highly Pathogenic Avian #Influenza (HPAI) #Spillover from Wild #Birds into Dairy #Cattle, https://etidiohnew.blogspot.com/2025/02/usa-nevada-occurrence-of-another-highly.html

Analysis of hemagglutinin gene of Nevada dairy cattle viruses did not identify changes predicted to impact #infectivity or #adaptation to mammalian hosts. However, a change of #PB2 D701N commonly associated with mammalian adaptation of HPAI virus was identified in viruses sequenced from four separate dairy cattle.

{#USA, #Nevada} The Occurrence of Another Highly Pathogenic Avian #Influenza (HPAI) #Spillover from Wild #Birds into Dairy #Cattle, https://etidiohnew.blogspot.com/2025/02/usa-nevada-occurrence-of-another-highly.html

Analysis of hemagglutinin gene of Nevada dairy cattle viruses did not identify changes predicted to impact #infectivity or #adaptation to mammalian hosts. However, a change of #PB2 D701N commonly associated with mammalian adaptation of HPAI virus was identified in viruses sequenced from four separate dairy cattle.

{#USA, #Nevada} The Occurrence of Another Highly Pathogenic Avian #Influenza (HPAI) #Spillover from Wild #Birds into Dairy #Cattle, https://etidiohnew.blogspot.com/2025/02/usa-nevada-occurrence-of-another-highly.html

Analysis of hemagglutinin gene of Nevada dairy cattle viruses did not identify changes predicted to impact #infectivity or #adaptation to mammalian hosts. However, a change of #PB2 D701N commonly associated with mammalian adaptation of HPAI virus was identified in viruses sequenced from four separate dairy cattle.

{#USA, #Nevada} The Occurrence of Another Highly Pathogenic Avian #Influenza (HPAI) #Spillover from Wild #Birds into Dairy #Cattle, https://etidiohnew.blogspot.com/2025/02/usa-nevada-occurrence-of-another-highly.html

Analysis of hemagglutinin gene of Nevada dairy cattle viruses did not identify changes predicted to impact #infectivity or #adaptation to mammalian hosts. However, a change of #PB2 D701N commonly associated with mammalian adaptation of HPAI virus was identified in viruses sequenced from four separate dairy cattle.

{#USA, #Nevada} The Occurrence of Another Highly Pathogenic Avian #Influenza (HPAI) #Spillover from Wild #Birds into Dairy #Cattle, https://etidiohnew.blogspot.com/2025/02/usa-nevada-occurrence-of-another-highly.html

Analysis of hemagglutinin gene of Nevada dairy cattle viruses did not identify changes predicted to impact #infectivity or #adaptation to mammalian hosts. However, a change of #PB2 D701N commonly associated with mammalian adaptation of HPAI virus was identified in viruses sequenced from four separate dairy cattle.

#Gene flow and its sporadic #spillover: #H10 and #N5 avian #influenza viruses from wild #birds and the #H10N5 #human cases in #China, https://etidiohnew.blogspot.com/2024/12/gene-flow-and-its-sporadic-spillover.html

Farmed #fur #animals harbour #viruses with #zoonotic #spillover potential, Nature: https://www.nature.com/articles/s41586-024-07901-3

We identified 7 species of #coronaviruses, expanding their known host range, & documented cross-species transmission of a novel #canine respiratory coronavirus to raccoon dogs & of #bat HKU5-like CoV to #mink, present at a high abundance in lung tissues. 3 subtypes of #influenza A virus—#H1N2, #H5N6 & #H6N2—were detected in #lungs of guinea pig, mink and #muskrat, respectively.

@iran @israel

"Threatened by a moderate Iranian president, Israel is pulling him into a fight"
By Lior Sternfeld: https://www.972mag.com/pezeshkian-israel-iran-haniyeh-war/

#escalation #confrontation #spill #spillOver #counterTerrorism #stateTerrorism #972Mag #MiddleEast #war #IsraelIran #IsraelIranWar #Tehran #Pezeshkian #Netanyahu #Haniyeh #Hamas #Iran #DefundIsrael #StopArmingIsrael #Zionism #CeasefireNow #StopFundingIsrael #LiorSternfeld

#Epidemiological #inference at threshold of #data availability: an #influenza #H1N2v #spillover event in #UK, J Roy Soc Interf.: https://royalsocietypublishing.org/doi/10.1098/rsif.2024.0168

From limited data available, we generate historical estimates of probability that #outbreak had died out in days following detection of the 1rst case. Our method suggests that outbreak could have been said to be over with 95% certainty between 19 & 29 days after 1rst case was detected, depending upon probability of a case being detected.

#Spillover of highly pathogenic avian #influenza #H5N1 virus to dairy #cattle, Nature: https://www.nature.com/articles/s41586-024-07849-4

Whole viral genome #sequences recovered from dairy #cows, #birds, domestic #cats, and a #raccoon from affected farms indicated multidirectional #interspecies #transmissions. Epidemiologic and genomic data revealed efficient cow-to-cow transmission after apparently healthy cows from an affected farm were transported to a premise in a different state.

Multiple #transatlantic #incursions of #HPAI clade 2.3.4.4b A(#H5N5) virus into North #America and #spillover to #mammals, Cell Rep.: https://www.cell.com/cell-reports/fulltext/S2211-1247(24)00808-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124724008088%3Fshowall%3Dtrue

#Seabirds likely enabled multiple incursions of A(H5N5) virus from #Europe to #Canada. Some A(H5N5) viruses possessed the mammalian #adaptation #marker #PB2-E627K. A(H5N5) viruses demonstrated rapid 100% #mortality and some transmission in #ferrets. A(H5N5) viruses preferred avian virus receptors and are sensitive to NA #inhibitors.

#Outbreaks of #H5N1 High Pathogenicity Avian #Influenza in #SouthAfrica in 2023 Were Caused by Two Distinct Sub-#Genotypes of Clade 2.3.4.4b Viruses, Viruses: https://www.mdpi.com/1999-4915/16/6/896

South African clade 2.3.4.4b H5N1 viruses had comparatively fewer #markers of #virulence and #pathogenicity compared to European strains, a possible reason why no #spillover to #mammals has occurred here yet.

From #birds to #mammals: #spillover of highly pathogenic avian #influenza #H5N1 virus to dairy #cattle led to efficient intra- and #interspecies #transmission http://biorxiv.org/cgi/content/short/2024.05.22.595317v1?rss=1

These results demonstrate the transmission of HPAI H5N1 clade 2.3.4.4b virus at a non-traditional interface and to a new and highly relevant livestock species, underscoring the ability of the virus to cross species barriers.

#Molecular #basis of #hippopotamus #ACE2 binding to #SARS-CoV-2, J Virol.: https://doi.org/10.1128/jvi.00451-24

These results provide crucial molecular insights into the susceptibility of hippopotami to SARS-CoV-2 and suggest the potential risk of SARS-CoV-2 VOCs #spillover and the necessity for #surveillance.

Protect where bats forage
Protect where bats roost
Include primary pandemic prevention alongside preparedness and response.

"While biomedical approaches are an essential part of the pandemic response toolbox, the genesis of a pandemic is rooted in ecological systems, necessitating ecological approaches for prevention."

"To reduce the likelihood of pandemics, we must protect where animals forage and rest so that we can keep wildlife healthy, minimize allostatic load, reduce the need for animals to alter their spatial behavior, and minimize risky human-wildlife encounters."
>>
Plowright, R.K., Ahmed, A.N., Coulson, T. et al. Ecological countermeasures to prevent pathogen spillover and subsequent pandemics. Nat Commun 15, 2577 (2024). https://doi.org/10.1038/s41467-024-46151-9
#Wildlife #habitat #destruction #degradation #fragmentation ##bats pandemics #HWI #biodiversity #conservation #deforestation #livestock #ungulates #grazing #horses #hendra #pathogens #spillover #ZoonoticRisk #roads #extractivism #sprawl #OneHealth #EcologicalCountermeasures

The Impact of Hypersonic Missiles on the Space Economy

#China #CommercialSpace #Constellations #Defense #Earth #GPS #HypersonicMissiles #Infrastructure #Launch #LaunchVehicles #Manufacturing #Materials #Military #Navigation #Propulsion #Radiation #Research #Russia #SatelliteServicing #Science #SpaceApplications #SpaceDebris #SpaceEconomy #SpaceExploration #SpaceIndustry #SpaceSector #SpaceTourism #Spacecraft #Spillover #Technology #UnitedStates #EarthAndOrbit #EditorSPicks #Launch #PolicyLawAndRegulation #SocioEconomic #SpaceEconomy

https://newspaceeconomy.ca/2024/03/18/the-impact-of-hypersonic-missiles-on-the-space-economy/

The Impact of Hypersonic Missiles on the Space Economy

#China #CommercialSpace #Constellations #Defense #Earth #GPS #HypersonicMissiles #Infrastructure #Launch #LaunchVehicles #Manufacturing #Materials #Military #Navigation #Propulsion #Radiation #Research #Russia #SatelliteServicing #Science #SpaceApplications #SpaceDebris #SpaceEconomy #SpaceExploration #SpaceIndustry #SpaceSector #SpaceTourism #Spacecraft #Spillover #Technology #UnitedStates #EarthAndOrbit #EditorSPicks #Launch #PolicyLawAndRegulation #SocioEconomic #SpaceEconomy

https://newspaceeconomy.ca/2024/03/18/the-impact-of-hypersonic-missiles-on-the-space-economy/

The Impact of Hypersonic Missiles on the Space Economy

#China #CommercialSpace #Constellations #Defense #Earth #GPS #HypersonicMissiles #Infrastructure #Launch #LaunchVehicles #Manufacturing #Materials #Military #Navigation #Propulsion #Radiation #Research #Russia #SatelliteServicing #Science #SpaceApplications #SpaceDebris #SpaceEconomy #SpaceExploration #SpaceIndustry #SpaceSector #SpaceTourism #Spacecraft #Spillover #Technology #UnitedStates #EarthAndOrbit #EditorSPicks #Launch #PolicyLawAndRegulation #SocioEconomic #SpaceEconomy

https://newspaceeconomy.ca/2024/03/18/the-impact-of-hypersonic-missiles-on-the-space-economy/

#Spillover of an endemic avian #Influenza #H6N2 #chicken lineage to #ostriches and #reassortment with clade 2.3.4.4b #H5N1 high pathogenicity viruses in chickens, Vet Res Commun.: https://link.springer.com/article/10.1007/s11259-023-10258-z

Lesenswert! :masto_reading:

Robert Zangerle über Normalität, Viren und Covid-19:

https://www.falter.at/seuchenkolumne/20230724/eine-hoechst-normale-seuchenkolumne

#covid #covid19 #covid19at #normal #normalität #nerz #schwein #ebola #dengue #hiv #rabies #influenza #sars-cov-2 #h1h1 #schwein #nerz #fleischindustrie #pelzindustrie #epidemiologie #mittelstand #mitte #ungleichheit #benachteiligung #schweinegrippe #monokultur #spillover #seuchenkolumne #zangerle

@Unfertig

PREPRINT (not yet peer reviewed): “SARS-CoV-2 occurrence in white-tailed #deer throughout their range in the conterminous #USA”

#Researchers collected >11k samples from deer 🦌 in 29 states 🇺🇸. #COVID was almost everywhere.

COVID prevalence declined over the course of the study, coincident with the rise of #Omicron, and the authors #hypothesize deer may be less susceptible.

With #diverse #hosts, COVID will continue to present a #complex #spillover #control #challenge.

https://www.biorxiv.org/content/10.1101/2023.04.14.533542v1

PREPRINT (not yet peer reviewed): “SARS-CoV-2 occurrence in white-tailed #deer throughout their range in the conterminous #USA”

#Researchers collected >11k samples from deer 🦌 in 29 states 🇺🇸. #COVID was almost everywhere.

COVID prevalence declined over the course of the study, coincident with the rise of #Omicron, and the authors #hypothesize deer may be less susceptible.

With #diverse #hosts, COVID will continue to present a #complex #spillover #control #challenge.

https://www.biorxiv.org/content/10.1101/2023.04.14.533542v1

PREPRINT (not yet peer reviewed): “SARS-CoV-2 occurrence in white-tailed #deer throughout their range in the conterminous #USA”

#Researchers collected >11k samples from deer 🦌 in 29 states 🇺🇸. #COVID was almost everywhere.

COVID prevalence declined over the course of the study, coincident with the rise of #Omicron, and the authors #hypothesize deer may be less susceptible.

With #diverse #hosts, COVID will continue to present a #complex #spillover #control #challenge.

https://www.biorxiv.org/content/10.1101/2023.04.14.533542v1

PREPRINT (not yet peer reviewed): “SARS-CoV-2 occurrence in white-tailed #deer throughout their range in the conterminous #USA”

#Researchers collected >11k samples from deer 🦌 in 29 states 🇺🇸. #COVID was almost everywhere.

COVID prevalence declined over the course of the study, coincident with the rise of #Omicron, and the authors #hypothesize deer may be less susceptible.

With #diverse #hosts, COVID will continue to present a #complex #spillover #control #challenge.

https://www.biorxiv.org/content/10.1101/2023.04.14.533542v1

PREPRINT (not yet peer reviewed): “SARS-CoV-2 occurrence in white-tailed #deer throughout their range in the conterminous #USA”

#Researchers collected >11k samples from deer 🦌 in 29 states 🇺🇸. #COVID was almost everywhere.

COVID prevalence declined over the course of the study, coincident with the rise of #Omicron, and the authors #hypothesize deer may be less susceptible.

With #diverse #hosts, COVID will continue to present a #complex #spillover #control #challenge.

https://www.biorxiv.org/content/10.1101/2023.04.14.533542v1

A recent #study published in the #LancetPlanetaryHealth #Journal #investigated the link between #FoodSystems , #zoonotic #diseases & #sustainability .
The #GlobalImpact of the #coronavirus disease 2019 #COVID19 #pandemic caused by the sudden outbreak of severe acute respiratory syndrome #coronavirus2 #SARSCoV2 underscored the need for #investigating the drivers of zoonotic #spillover events.

https://www.news-medical.net/amp/news/20230411/Food-systems-and-pandemic-risks-exploring-the-connection-between-zoonotic-spillovers-and-sustainable-agriculture.aspx

#Biology #medical #science #research #Interconnected #ScientificStudy #Health

Pandas in Wuhan market? China’s COVID genetic study is out—it has problems - Enlarge / Giant panda cub Huanlili plays with a bamboo during her first... - https://arstechnica.com/?p=1929768 #infectiousdisease #intermediatehost #naturalspillover #geneticdata #raccoondog #spillover #chinacdc #covid-19 #pandemic #science #wuhan

Here’s the full analysis of newly uncovered genetic data on COVID’s origins - Enlarge / Security guards stand in front of the closed Huanan Seafood W... - https://arstechnica.com/?p=1925722 #sars-cov-2origin #genomicdata #sars-cov-2 #spillover #covid-19 #outbreak #pandemic #science #genetic #lableak #gisaid #huanan #wuhan #who

Jan 13 at 10am pst
Raina Plowright: Preventing the next Pandemic by Preventing Spillover

@epiverse
@idjclub #IDMastodon #onehealth #pandemics #spillover #DiseaseDynamics #epiverse #DisEcol #Bats #GlobalHealth

Spread the word @noamross
@DNAdataPhile
@ProfKen
@EdMHill
@olireiv
@ddestoum
@maciekboni
@andreashandel

https://calendar.ucsf.edu/event/eppicenter_seminar_raina_plowright_5699

¿Se podrían prevenir los #spillover plantando árboles?

Este estudio encuentra que la escasez de alimentos en la población de murciélagos impulsada por el clima precedió a los brotes del virus #Hendra.

Este estudio sugiere que una forma efectiva de prevenir la próxima pandemia es proteger y restaurar los hábitats de la vida silvestre.

https://www.nature.com/articles/s41586-022-05506-2

"Specifically, the researchers found that clusters of #Hendra virus spillovers occur following years in which the bats experience food stress. And these food shortages typically follow years with a strong El Niño, a climatic phenomenon in the tropical Pacific Ocean that is often associated with drought along eastern Australia. But if the trees the bats rely on for food during the winter have a large flowering event the year after there’s been a food shortage, there are no spillovers. Unfortunately, the problem is “there’s hardly any winter habitat left,” says Raina Plowright, a disease ecologist and study co-author at Cornell University in Ithaca, New York."

#Virology #spillover

https://www.nature.com/articles/d41586-022-03682-9

#introduction
Hi all. I'm just starting to explore mastadon. I'm a #diseaseecologist who studies #zoonotic #viruses in wildlife and how they #spillover into livestock and people. I work for a science-based nonprofit called EcoHealth Alliance. My research focuses on #bats and their associated #henipaviruses, #coronaviruses and #filoviruses in Asia and Africa.