home.social

#olfaction — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #olfaction, aggregated by home.social.

  1. "Rapid temporal processing in the olfactory bulb underlies concentration-invariant odor identification and signal decorrelation", Karadas et al. 2026 (Dima Rinberg's lab).
    nature.com/articles/s41593-026

    Circuits in the mouse olfactory bulb implement a rapid filter:

    "Animals who rely on smell need to identify and discriminate odors despite fluctuations in concentration, yet odor receptor activation is strongly concentration dependent. [...] We found that the glomeruli [...] activated earliest in a sniff robustly represented odor identity across concentrations, ... . [via] a short temporal window of excitability at a sniff’s onset, followed by prolonged odor-evoked inhibition. The OB implements a rapid temporal filter, which is responsible for stabilizing identity across concentrations while decorrelating responses between odors."

    #neuroscience #olfaction #mouse

  2. "Rapid temporal processing in the olfactory bulb underlies concentration-invariant odor identification and signal decorrelation", Karadas et al. 2026 (Dima Rinberg's lab).
    nature.com/articles/s41593-026

    Circuits in the mouse olfactory bulb implement a rapid filter:

    "Animals who rely on smell need to identify and discriminate odors despite fluctuations in concentration, yet odor receptor activation is strongly concentration dependent. [...] We found that the glomeruli [...] activated earliest in a sniff robustly represented odor identity across concentrations, ... . [via] a short temporal window of excitability at a sniff’s onset, followed by prolonged odor-evoked inhibition. The OB implements a rapid temporal filter, which is responsible for stabilizing identity across concentrations while decorrelating responses between odors."

    #neuroscience #olfaction #mouse

  3. "Rapid temporal processing in the olfactory bulb underlies concentration-invariant odor identification and signal decorrelation", Karadas et al. 2026 (Dima Rinberg's lab).
    nature.com/articles/s41593-026

    Circuits in the mouse olfactory bulb implement a rapid filter:

    "Animals who rely on smell need to identify and discriminate odors despite fluctuations in concentration, yet odor receptor activation is strongly concentration dependent. [...] We found that the glomeruli [...] activated earliest in a sniff robustly represented odor identity across concentrations, ... . [via] a short temporal window of excitability at a sniff’s onset, followed by prolonged odor-evoked inhibition. The OB implements a rapid temporal filter, which is responsible for stabilizing identity across concentrations while decorrelating responses between odors."

    #neuroscience #olfaction #mouse

  4. "Rapid temporal processing in the olfactory bulb underlies concentration-invariant odor identification and signal decorrelation", Karadas et al. 2026 (Dima Rinberg's lab).
    nature.com/articles/s41593-026

    Circuits in the mouse olfactory bulb implement a rapid filter:

    "Animals who rely on smell need to identify and discriminate odors despite fluctuations in concentration, yet odor receptor activation is strongly concentration dependent. [...] We found that the glomeruli [...] activated earliest in a sniff robustly represented odor identity across concentrations, ... . [via] a short temporal window of excitability at a sniff’s onset, followed by prolonged odor-evoked inhibition. The OB implements a rapid temporal filter, which is responsible for stabilizing identity across concentrations while decorrelating responses between odors."

    #neuroscience #olfaction #mouse

  5. "Rapid temporal processing in the olfactory bulb underlies concentration-invariant odor identification and signal decorrelation", Karadas et al. 2026 (Dima Rinberg's lab).
    nature.com/articles/s41593-026

    Circuits in the mouse olfactory bulb implement a rapid filter:

    "Animals who rely on smell need to identify and discriminate odors despite fluctuations in concentration, yet odor receptor activation is strongly concentration dependent. [...] We found that the glomeruli [...] activated earliest in a sniff robustly represented odor identity across concentrations, ... . [via] a short temporal window of excitability at a sniff’s onset, followed by prolonged odor-evoked inhibition. The OB implements a rapid temporal filter, which is responsible for stabilizing identity across concentrations while decorrelating responses between odors."

    #neuroscience #olfaction #mouse

  6. Hunter-gatherers in Malaysia have better-preserved smell genes than farmers — and new genomics research explains why. How you live shapes what your nose can detect, all the way down to your DNA.
    #HumanEvolution #Genomics #Olfaction anthropology.net/p/what-hunter

  7. Hunter-gatherers in Malaysia have better-preserved smell genes than farmers — and new genomics research explains why. How you live shapes what your nose can detect, all the way down to your DNA.
    #HumanEvolution #Genomics #Olfaction anthropology.net/p/what-hunter

  8. Hunter-gatherers in Malaysia have better-preserved smell genes than farmers — and new genomics research explains why. How you live shapes what your nose can detect, all the way down to your DNA.
    #HumanEvolution #Genomics #Olfaction anthropology.net/p/what-hunter

  9. Hunter-gatherers in Malaysia have better-preserved smell genes than farmers — and new genomics research explains why. How you live shapes what your nose can detect, all the way down to your DNA.
    #HumanEvolution #Genomics #Olfaction anthropology.net/p/what-hunter

  10. Hunter-gatherers in Malaysia have better-preserved smell genes than farmers — and new genomics research explains why. How you live shapes what your nose can detect, all the way down to your DNA.
    #HumanEvolution #Genomics #Olfaction anthropology.net/p/what-hunter

  11. 📰 "Machine Learning Based Modelling of Human and Insect Olfaction Screens Millions of compounds to Identify Pleasant Smelling Insect Repellents"
    doi.org/doi:10.1101/2023.12.25
    pubmed.ncbi.nlm.nih.gov/419594
    #Drosophila #Olfaction

  12. 📰 "Machine Learning Based Modelling of Human and Insect Olfaction Screens Millions of compounds to Identify Pleasant Smelling Insect Repellents"
    doi.org/doi:10.1101/2023.12.25
    pubmed.ncbi.nlm.nih.gov/419594
    #Drosophila #Olfaction

  13. 📰 "Machine Learning Based Modelling of Human and Insect Olfaction Screens Millions of compounds to Identify Pleasant Smelling Insect Repellents"
    doi.org/doi:10.1101/2023.12.25
    pubmed.ncbi.nlm.nih.gov/419594
    #Drosophila #Olfaction

  14. 📰 "Machine Learning Based Modelling of Human and Insect Olfaction Screens Millions of compounds to Identify Pleasant Smelling Insect Repellents"
    doi.org/doi:10.1101/2023.12.25
    pubmed.ncbi.nlm.nih.gov/419594
    #Drosophila #Olfaction

  15. 📰 "Age-dependent H3K9 trimethylation by dSetdb1 impairs mitochondrial UPR leading to degeneration of olfactory neurons and loss of olfactory function in Drosophila"
    doi.org/doi:10.7554/eLife.1031
    pubmed.ncbi.nlm.nih.gov/418853
    #Mitochondria #Olfaction
    #Drosophila #Sensory

  16. 📰 "Age-dependent H3K9 trimethylation by dSetdb1 impairs mitochondrial UPR leading to degeneration of olfactory neurons and loss of olfactory function in Drosophila"
    doi.org/doi:10.7554/eLife.1031
    pubmed.ncbi.nlm.nih.gov/418853
    #Mitochondria #Olfaction
    #Drosophila #Sensory

  17. 📰 "Age-dependent H3K9 trimethylation by dSetdb1 impairs mitochondrial UPR leading to degeneration of olfactory neurons and loss of olfactory function in Drosophila"
    doi.org/doi:10.7554/eLife.1031
    pubmed.ncbi.nlm.nih.gov/418853
    #Mitochondria #Olfaction
    #Drosophila #Sensory

  18. 📰 "Age-dependent H3K9 trimethylation by dSetdb1 impairs mitochondrial UPR leading to degeneration of olfactory neurons and loss of olfactory function in Drosophila"
    doi.org/doi:10.7554/eLife.1031
    pubmed.ncbi.nlm.nih.gov/418853
    #Mitochondria #Olfaction
    #Drosophila #Sensory

  19. Now diving into the processing and transformation of raw olfactory stimulation of sensory neurons to the output of the olfactory neuropils via projection neurons, see these two papers, one in fly and one in zebrafish. The former shows how PNs respond to the derivative of the input, which is essential for tracking stimuli up a gradient, and the latter shows how the LNs perform a whitening of the olfactory input (to decorrelate the inputs into the otherwise multiply stimulated olfactory receptors and their corresponding sensory neurons) which optimally prepares similar stimuli for separation:

    Kim AJ, Lazar AA, Slutskiy YB. Projection neurons in Drosophila antennal lobes signal the acceleration of odor concentrations. Elife. 2015 May 14;4:e06651.
    elifesciences.org/articles/6651

    Wanner AA, Friedrich RW. Whitening of odor representations by the wiring diagram of the olfactory bulb. Nature neuroscience. 2020 Mar;23(3):433-42.
    nature.com/articles/s41593-019

    4/4

    #neuroscience #olfaction #Drosophila #mouse #zebrafish

  20. Now diving into the processing and transformation of raw olfactory stimulation of sensory neurons to the output of the olfactory neuropils via projection neurons, see these two papers, one in fly and one in zebrafish. The former shows how PNs respond to the derivative of the input, which is essential for tracking stimuli up a gradient, and the latter shows how the LNs perform a whitening of the olfactory input (to decorrelate the inputs into the otherwise multiply stimulated olfactory receptors and their corresponding sensory neurons) which optimally prepares similar stimuli for separation:

    Kim AJ, Lazar AA, Slutskiy YB. Projection neurons in Drosophila antennal lobes signal the acceleration of odor concentrations. Elife. 2015 May 14;4:e06651.
    elifesciences.org/articles/6651

    Wanner AA, Friedrich RW. Whitening of odor representations by the wiring diagram of the olfactory bulb. Nature neuroscience. 2020 Mar;23(3):433-42.
    nature.com/articles/s41593-019

    4/4

    #neuroscience #olfaction #Drosophila #mouse #zebrafish

  21. Now diving into the processing and transformation of raw olfactory stimulation of sensory neurons to the output of the olfactory neuropils via projection neurons, see these two papers, one in fly and one in zebrafish. The former shows how PNs respond to the derivative of the input, which is essential for tracking stimuli up a gradient, and the latter shows how the LNs perform a whitening of the olfactory input (to decorrelate the inputs into the otherwise multiply stimulated olfactory receptors and their corresponding sensory neurons) which optimally prepares similar stimuli for separation:

    Kim AJ, Lazar AA, Slutskiy YB. Projection neurons in Drosophila antennal lobes signal the acceleration of odor concentrations. Elife. 2015 May 14;4:e06651.
    elifesciences.org/articles/6651

    Wanner AA, Friedrich RW. Whitening of odor representations by the wiring diagram of the olfactory bulb. Nature neuroscience. 2020 Mar;23(3):433-42.
    nature.com/articles/s41593-019

    4/4

    #neuroscience #olfaction #Drosophila #mouse #zebrafish

  22. Now diving into the processing and transformation of raw olfactory stimulation of sensory neurons to the output of the olfactory neuropils via projection neurons, see these two papers, one in fly and one in zebrafish. The former shows how PNs respond to the derivative of the input, which is essential for tracking stimuli up a gradient, and the latter shows how the LNs perform a whitening of the olfactory input (to decorrelate the inputs into the otherwise multiply stimulated olfactory receptors and their corresponding sensory neurons) which optimally prepares similar stimuli for separation:

    Kim AJ, Lazar AA, Slutskiy YB. Projection neurons in Drosophila antennal lobes signal the acceleration of odor concentrations. Elife. 2015 May 14;4:e06651.
    elifesciences.org/articles/6651

    Wanner AA, Friedrich RW. Whitening of odor representations by the wiring diagram of the olfactory bulb. Nature neuroscience. 2020 Mar;23(3):433-42.
    nature.com/articles/s41593-019

    4/4

    #neuroscience #olfaction #Drosophila #mouse #zebrafish

  23. Now diving into the processing and transformation of raw olfactory stimulation of sensory neurons to the output of the olfactory neuropils via projection neurons, see these two papers, one in fly and one in zebrafish. The former shows how PNs respond to the derivative of the input, which is essential for tracking stimuli up a gradient, and the latter shows how the LNs perform a whitening of the olfactory input (to decorrelate the inputs into the otherwise multiply stimulated olfactory receptors and their corresponding sensory neurons) which optimally prepares similar stimuli for separation:

    Kim AJ, Lazar AA, Slutskiy YB. Projection neurons in Drosophila antennal lobes signal the acceleration of odor concentrations. Elife. 2015 May 14;4:e06651.
    elifesciences.org/articles/6651

    Wanner AA, Friedrich RW. Whitening of odor representations by the wiring diagram of the olfactory bulb. Nature neuroscience. 2020 Mar;23(3):433-42.
    nature.com/articles/s41593-019

    4/4

    #neuroscience #olfaction #Drosophila #mouse #zebrafish

  24. And in flies in particular, all papers signed by Rachel Wilson as the senior author (now a professor at Harvard Medical School) in the early 2000s are absolutely outstanding, on probing with electrophysiology and genetics the various synapses in the fruit fly olfactory system, e.g., the sensory neuron (ORN or OSN, synonyms) to the projection neurons (PNs), or the local neurons (LNs), or the LNs to each other or to the PNs, and the PNs back to the LNs. She's written a couple of reviews on the subject that are very accessible for the curious student.

    Click on "Publications" and expand them, to find the ones published in Current Opinion in Neurobiology or in the Annual Review Neuroscience:
    neuro.hms.harvard.edu/faculty-

    ... like e.g., this one:
    Wilson RI. Early olfactory processing in Drosophila: mechanisms and principles. Annual review of neuroscience. 2013 Jul 8;36(1):217-41.
    annualreviews.org/content/jour

    Rachel's more recent work is on neural networks in the fly for spatial navigation.

    3/4

    #neuroscience #olfaction #Drosophila #mouse #zebrafish

  25. And in flies in particular, all papers signed by Rachel Wilson as the senior author (now a professor at Harvard Medical School) in the early 2000s are absolutely outstanding, on probing with electrophysiology and genetics the various synapses in the fruit fly olfactory system, e.g., the sensory neuron (ORN or OSN, synonyms) to the projection neurons (PNs), or the local neurons (LNs), or the LNs to each other or to the PNs, and the PNs back to the LNs. She's written a couple of reviews on the subject that are very accessible for the curious student.

    Click on "Publications" and expand them, to find the ones published in Current Opinion in Neurobiology or in the Annual Review Neuroscience:
    neuro.hms.harvard.edu/faculty-

    ... like e.g., this one:
    Wilson RI. Early olfactory processing in Drosophila: mechanisms and principles. Annual review of neuroscience. 2013 Jul 8;36(1):217-41.
    annualreviews.org/content/jour

    Rachel's more recent work is on neural networks in the fly for spatial navigation.

    3/4

    #neuroscience #olfaction #Drosophila #mouse #zebrafish

  26. And in flies in particular, all papers signed by Rachel Wilson as the senior author (now a professor at Harvard Medical School) in the early 2000s are absolutely outstanding, on probing with electrophysiology and genetics the various synapses in the fruit fly olfactory system, e.g., the sensory neuron (ORN or OSN, synonyms) to the projection neurons (PNs), or the local neurons (LNs), or the LNs to each other or to the PNs, and the PNs back to the LNs. She's written a couple of reviews on the subject that are very accessible for the curious student.

    Click on "Publications" and expand them, to find the ones published in Current Opinion in Neurobiology or in the Annual Review Neuroscience:
    neuro.hms.harvard.edu/faculty-

    ... like e.g., this one:
    Wilson RI. Early olfactory processing in Drosophila: mechanisms and principles. Annual review of neuroscience. 2013 Jul 8;36(1):217-41.
    annualreviews.org/content/jour

    Rachel's more recent work is on neural networks in the fly for spatial navigation.

    3/4

    #neuroscience #olfaction #Drosophila #mouse #zebrafish

  27. And in flies in particular, all papers signed by Rachel Wilson as the senior author (now a professor at Harvard Medical School) in the early 2000s are absolutely outstanding, on probing with electrophysiology and genetics the various synapses in the fruit fly olfactory system, e.g., the sensory neuron (ORN or OSN, synonyms) to the projection neurons (PNs), or the local neurons (LNs), or the LNs to each other or to the PNs, and the PNs back to the LNs. She's written a couple of reviews on the subject that are very accessible for the curious student.

    Click on "Publications" and expand them, to find the ones published in Current Opinion in Neurobiology or in the Annual Review Neuroscience:
    neuro.hms.harvard.edu/faculty-

    ... like e.g., this one:
    Wilson RI. Early olfactory processing in Drosophila: mechanisms and principles. Annual review of neuroscience. 2013 Jul 8;36(1):217-41.
    annualreviews.org/content/jour

    Rachel's more recent work is on neural networks in the fly for spatial navigation.

    3/4

    #neuroscience #olfaction #Drosophila #mouse #zebrafish