#connectomics — Public Fediverse posts

#KnowledgeBit: #Neural mapping uses advanced imaging and AI to map brain circuits and connections at cellular precision, enabling breakthroughs in treating neurological disorders, guiding neurosurgery, and advancing AI—a effort exemplified by #Google’s high-resolution #connectomics projects.

https://knowledgezone.co.in/trends/browser?topic=Neural-Mapping

Research assistant positions available to contribute to map the brain connectome of the mosquito Aedes aegypti, in the groups of Lisa Marin and Greg Jefferis in Cambridge, UK.

https://flyconnecto.me/2026/08/01/the-aedes-team-is-recruiting/

Note many who held such positions for a year or two went on to do a PhD in neuroscience afterwards.

#neuroscience #PhDJobs #Fedihire #Aedes #mosquitoes #connectomics

In our new preprint, Réza Shahidi, Alexandra Kerbl and Karel Mocaer give an exquisitely detailed manual on serial sectioning for electron microscopy.

"Volume Electron Microscopy: Tips & Tricks on Micromanipulator-Assisted Serial Sectioning for Array Tomography"

https://zenodo.org/records/21699226

#EM #connectomics #vEM #microscopy

If you are interested in nervous system evolution you may want to read our review with Kei Jokura on nerve nets:

"Revisiting nerve nets: functional organization and evolutionary implication"

https://link.springer.com/article/10.1038/s44318-026-00879-w

#evolution #neuroscience #connectomics #vEM @EMBOPress

We are hiring:

Machine Learning Engineer at the #MRCLMB in Cambridge, UK. On site only.

«To lead the deployment, scaling and maintenance of machine learning systems for petabyte-scale connectomics data within the group of Dr. Albert Cardona at the MRC Laboratory of Molecular Biology. The role will focus on turning machine learning models for volume electron microscopy into robust, reproducible and observable production pipelines, supporting automated segmentation, synapse detection, proofreading and large-scale image analysis.»

Apply before 10th of August, 2026.

https://fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com/hcmUI/CandidateExperience/en/sites/UKRI-Careers/job/2611

See also:
* https://mohinta2892.github.io/catena-docs.github.io/getting-started/
* https://mrclmb.ac.uk/research-leaders/albert-cardona/

#connectomics #Fedihire #PhDJobs #MachineLearning #BioimageInformatics

📰 "A global molecular code for birth order and neuronal identity in Drosophila"
https://doi.org/doi:10.1038/s41586-026-10797-w
https://pubmed.ncbi.nlm.nih.gov/42486976/
#Connectomics
#Drosophila

"These observations argue that both local intrajunctional and long-distance interjunctional synaptic competition are activity-mediated and that the structure of mature neural circuits arises from the activity patterns of developing circuits."

From: "Connectomic evidence that ordered activity drives neuromuscular network formation", Yaron Meirovitch et al. 2026 (Lichtman lab).
https://www.nature.com/articles/s41593-026-02344-7

#connectomics #neuroscience #NeuralDevelopment #DevBiol

📰 "Connectomic Analysis of Mitochondria in the Central Brain of Drosophila"
https://doi.org/doi:10.1101/2024.04.21.590464
https://pubmed.ncbi.nlm.nih.gov/42395513/
#Connectomics
#Mitochondria #Drosophila #Metabolism

RE: https://biologists.social/@biorxiv_neursci/116850810249684892

“Connectome-constrained networks produce a smooth circular direction geometry that random networks cannot replicate”

“The core finding — that behavioral fidelity does not imply representational fidelity — extends the cautionary tale of Brunton et al. (Brunton et al., 2026) in a complementary direction. Where they showed that a worm connectome trained with deep reinforcement learning produces realistic fly walking, we show that a stability-constrained random network with the same architecture cannot
replicate the connectome’s representational geometry even when its behavioral output is functionally equivalent.”

#neuroscience #connectomics #Drosophila

The lab of Xiaotang Lu is hiring, at University of Illinois. From her lab's webpage:

«Three Postdoc positions are immediately open

a) Biochemistry: experience in protein engineering, molecular probe design, preparation, and the application of advanced imaging platforms to complex tissue samples.

b) Neurobiology: experience in systems neuroscience, circuit neuroscience, and related diseases.

c) Computational science: experience in large imaging data segmentation and analysis, and/or computational protein design.»

https://neurolab.chemistry.illinois.edu/recruit

See also her research page, on the chemistry of #connectomics
https://neurolab.chemistry.illinois.edu/research

#neuroscience #PhDJobs #FediHire

📰 "VFB-MCP: Natural-Language Access to Drosophila Neuroscience Grounded by an Expert-Curated Ontology-Led Knowledgebase"
https://www.biorxiv.org/content/10.64898/2026.06.16.732577v1?rss=1
#Connectomics
#Neuroscience
#Drosophila

📰 "Olfactory Loss Enhances Visual Learning in Drosophila through Structural and Functional Reorganisation"
https://www.biorxiv.org/content/10.64898/2026.06.16.732444v1?rss=1
#Connectomics
#Drosophila #Olfaction
#Sensory
#Adult
#Larva

📰 "Uncovering Sex Differences in the Drosophila Ventral Nerve Cord Through Connectome Alignment"
https://www.biorxiv.org/content/10.64898/2026.06.14.732053v1?rss=1
#Connectomics
#Drosophila

A complete connectome is a highly detailed, three-dimensional wiring diagram mapping all neural connections between the brain and the nerve cord (the spinal cord equivalent) of an adult fruit fly. This comprehensive map allows scientists to observe all neurons and their synaptic connections as a single, holistic functional unit.
#Neuroscience #Neurobiology #Connectomics #ComputationalBiology #sflorg
https://www.sflorg.com/2026/06/ns06092601.html

2+2 years position for a software engineer / data scientist with serious programming chops in my lab at the #MRCLMB to develop tech for #connectomics and #neuroscience :

https://fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com/hcmUI/CandidateExperience/en/sites/UKRI-Careers/job/2250

Please do share with suitable candidates, and feel free to reach out via email to discuss details.

Deadline for application: May 10th.

Starting date: any within 2026.

Requires Masters plus industry experience, or a PhD in a suitable field – and demonstrable experience in software engineering.

Please help disseminate – either here or by copy-pasting onto emails or messages. Thank you!

#PhDJobs #neuroscience #SoftwareEngineering #jobs #ScienceJobs

@tuthill

If interested in this topic, Prof. Bing Brunton gave a talk at #Cosyne2026 which is very much worth watching:

https://youtu.be/yhUBq5R01qA?t=3430

Among other topics, Bing presents the minimal network for the oscillatory behaviour that sustains walking, and also the embodiment of a connectome by plugging it into a virtual mechanical model of the fly, #MuJoCo from the #AnyBrain #HHMIJanelia project team.

#neuroscience #Drosophila #connectomics

Postdoc position: Career Returner Fellowship

"The LMB is proud to launch a three-year fully funded fellowship for scientists who have had a career break of 12 months or more."

"At the LMB, we understand that stepping away from research – even briefly – can affect career progression. That is why we have created a dedicated postdoctoral fellowship to support researchers who have taken a career break of 12 months or more, for any reason, for example parental leave, health reasons, caregiving, a career change or other personal circumstances."

https://mrclmb.ac.uk/careers-and-people/postdocs/career-returner-fellowship/

Happy to discuss applications to our lab in #Drosophila #connectomics, #ElectronMicroscopy or #ComputerVision applied to #BioimageInformatics.

#MRCLMB #PhDJobs #neuroscience

Shawn Mikula's https://connectomes.org/ doesn't load, but the domain name is registered. Does anyone know who is maintaining the site?

#neuroscience #connectomics

@jekely

Now out as a version of record:

"Neural connectome of the ctenophore statocyst", Jokura et sl. 2026 (Jékely lab)

https://elifesciences.org/articles/108420#content

#ctenophore #connectomics #neuroscience

@teixi

By the way, unlike what the piece says, Murrhy and Seung did NOT "have the idea to use those images to identify and map the connections between each visible neuron, creating a connectome".

That idea had been floating about the field since Brenner and his C. elegans connectome, and those in a position to execute were the groups at Janelia with discretionary HHMI finding, like Rubin, Bock and myself. And we did.

What the Seung lab did was capitalise on the published EM volume of the adult female fly brain to apply more effective image registration and neuron segmentation approaches than the ones tried so far at that point by the Fly EM Project Team at Janelia. Synapses were detected by Julia Buhmann in saalfeld's lab at Janelia as well. The research groups led by Seung, Jefferis (at MRC LMB) and Murthy then put in the gargantuan effort of proofreading to deliver the published connectome.

#Drosophila #connectomics #FAFB

Sunday slow rereading on #neuroscience #drosophila #flybrain #electromicroscopy #connectomics #omics

Holy Molly forgot this top notch quotation!?

,There is a before and after connectome—B.C. and A.C.’

@albertcardona referencing a well-known quote from #columbiaun #TheoreticalNeuroscience Larry Abbott

with this follow-up:

,It’s the end of the beginning’

https://www.science.org/content/article/complete-map-fruit-fly-brain-circuitry-unveiled

We are hiring! SPecifically, a PostDoc for data management and connectomics as part of a large clinical research group. The details can be found here: https://www.linkedin.com/posts/epiconn_open-position-apply-now-the-epiconn-activity-7413211951125688320-Wqi5

Please apply if you are interested in up to four years in Vienna, one of the most liveable cities in the world!

#university #medicaluniversityofvienna
#research #vienna #austria #ismrm #mri #7Tesla #epilepsy #connectomics #data_management

Can neuroscientists decode memories solely from a map of synaptic connections?
| Five experts discuss the progress, possibilities and hurdles of decoding a “nontrivial” memory from an organism just by analyzing its brain connectivity patterns |
The Transmitter: Neuroscience News and Perspectives
🎧🤷
https://www.thetransmitter.org/brain-inspired/can-neuroscientists-decode-memories-solely-from-a-map-of-synaptic-connections/

#neuroscience #connectomics #memory #TheTransmitter

📰 "Whole-brain connectomics of Drosophila reveals a robust, distributed architecture for the suppression of feeding during escape"
https://www.biorxiv.org/content/10.64898/2025.12.14.694122v1?rss=1
#Connectomics
#Drosophila

Our dispatch:

https://www.sciencedirect.com/science/article/pii/S0960982225014691

on the recent Hydra volume EM paper by Zhang, Rafa Yuste and colleagues:

#connectomics, without synapses

https://www.sciencedirect.com/science/article/pii/S0960982225013090

#neuroscience

X-ray imaging at under 40 nm resolution without destroying the tissue: a demonstration by Wanner, Díaz, Schaefer and Bosch.

Based on radiation-had epoxy resin borrowed from the aerospace and nuclear industries.

"Tissue samples were resistant to radiation doses exceeding 1.15 × 1010 Gy, and sub-40 nm isotropic resolution allowed identifying axon bundles, dendrites and synapses in mouse brain tissue without physical sectioning."

"Nondestructive X-ray tomography of brain tissue ultrastructure", Bosch et al. 2025
https://www.nature.com/articles/s41592-025-02891-0

#neuroscience #connectomics #Xptychography