📰 "A male-specific neural circuit for appetitive thirst in Drosophila"
https://www.biorxiv.org/content/10.64898/2026.10.08.757749v1?rss=1
#Connectomics
#Drosophila #Behaviour #Sensory
#connectomics — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #connectomics, aggregated by home.social.
-
-
In our new paper by Kata Szabó @Kata_Szabo
et al. we present optimised sample-preparation workflows for volume electron microscopy for entire small marine organisms. The workflow includes high-pressure freezing, various freeze substitution protocols and synchrotron X-ray imaging in Hamburg @DESY and ESRF Grenoble.https://www.biorxiv.org/content/10.64898/2026.10.06.756938v1
@ZooCELL
#Platynereis #microscopy #synchrotron #xray #vEM #connectomics -
If you are interested in serial sectioning for electron microscopy, we have now uploaded a revised version of our paper
Shahidi et al:
"Volume Electron Microscopy: Tips & Tricks on Micromanipulator-Assisted Serial Sectioning for Array Tomography"
-
https://www.europesays.com/ie/704686/ NSF awards $19 million to build 3D biological observatory for revealing life’s smallest structures #ArtificialIntelligence #Brain #Cell #Connectomics #education #Éire #Electron #ElectronMicroscopy #eye #HighThroughput #IE #imaging #Ireland #Laboratory #medicine #Microscope #Microscopy #Neurodegeneration #Neurons #Neuroscience #Research #SamplePreparation #Science
-
The context: 4 publications on the newly released and analysed whole male fruit fly central nervous system connectome.
"Sexual dimorphism in the complete Drosophila male central nervous system connectome", Berg et al. 2026
https://www.cell.com/cell/fulltext/S0092-8674(26)00942-6"Networks of sexually dimorphic neurons that regulate social behaviors in Drosophila", Rubin et al. 2026
https://www.cell.com/current-biology/fulltext/S0960-9822(26)01023-7"The complete gustatory connectome of adult Drosophila reveals how taste guides feeding, foraging, and social behavior", Tastekin et al. 2026
https://www.cell.com/cell/fulltext/S0092-8674(26)00943-8"The organization of visual pathways in the Drosophila brain", Hoeller et al. 2026
https://www.cell.com/cell/fulltext/S0092-8674(26)00941-4 -
Gerry Rubin and Harald Hess candidly explain, in a video, what it took to map the fruit fly central nervous system, aka the connectome. Mostly: identify good scientists, trust them, fund them long term, don't bug them endlessly with administrative work.
https://www.hhmi.org/news/scientists-complete-full-map-fruit-fly-brain-connectome
-
Google-Aided Research Completes First Full Map Of Male Fruit Fly Brain's 1.6 Lakh Neurons
-
Google-Aided Research Completes First Full Map Of Male Fruit Fly Brain's 1.6 Lakh Neurons
-
#KnowledgeBit: #Neural mapping uses advanced imaging and AI to map brain circuits and connections at cellular precision, enabling breakthroughs in treating neurological disorders, guiding neurosurgery, and advancing AI—a effort exemplified by #Google’s high-resolution #connectomics projects.
https://knowledgezone.co.in/trends/browser?topic=Neural-Mapping
-
https://www.europesays.com/ie/618014/ Speaking More Languages May Slow Brain Aging #Aging #CognitiveScience #Connectomics #Éire #Health #IE #Ireland #Language #Neuroscience
-
Research assistant positions available to contribute to map the brain connectome of the mosquito Aedes aegypti, in the groups of Lisa Marin and Greg Jefferis in Cambridge, UK.
https://flyconnecto.me/2026/08/01/the-aedes-team-is-recruiting/
Note many who held such positions for a year or two went on to do a PhD in neuroscience afterwards.
#neuroscience #PhDJobs #Fedihire #Aedes #mosquitoes #connectomics
-
In our new preprint, Réza Shahidi, Alexandra Kerbl and Karel Mocaer give an exquisitely detailed manual on serial sectioning for electron microscopy.
"Volume Electron Microscopy: Tips & Tricks on Micromanipulator-Assisted Serial Sectioning for Array Tomography"
-
If you are interested in nervous system evolution you may want to read our review with Kei Jokura on nerve nets:
"Revisiting nerve nets: functional organization and evolutionary implication"
https://link.springer.com/article/10.1038/s44318-026-00879-w
-
We are hiring:
Machine Learning Engineer at the #MRCLMB in Cambridge, UK. On site only.
«To lead the deployment, scaling and maintenance of machine learning systems for petabyte-scale connectomics data within the group of Dr. Albert Cardona at the MRC Laboratory of Molecular Biology. The role will focus on turning machine learning models for volume electron microscopy into robust, reproducible and observable production pipelines, supporting automated segmentation, synapse detection, proofreading and large-scale image analysis.»
Apply before 10th of August, 2026.
See also:
* https://mohinta2892.github.io/catena-docs.github.io/getting-started/
* https://mrclmb.ac.uk/research-leaders/albert-cardona/#connectomics #Fedihire #PhDJobs #MachineLearning #BioimageInformatics
-
📰 "A global molecular code for birth order and neuronal identity in Drosophila"
https://doi.org/doi:10.1038/s41586-026-10797-w
https://pubmed.ncbi.nlm.nih.gov/42486976/
#Connectomics
#Drosophila -
"These observations argue that both local intrajunctional and long-distance interjunctional synaptic competition are activity-mediated and that the structure of mature neural circuits arises from the activity patterns of developing circuits."
From: "Connectomic evidence that ordered activity drives neuromuscular network formation", Yaron Meirovitch et al. 2026 (Lichtman lab).
https://www.nature.com/articles/s41593-026-02344-7 -
📰 "Connectomic Analysis of Mitochondria in the Central Brain of Drosophila"
https://doi.org/doi:10.1101/2024.04.21.590464
https://pubmed.ncbi.nlm.nih.gov/42395513/
#Connectomics
#Mitochondria #Drosophila #Metabolism -
RE: https://biologists.social/@biorxiv_neursci/116850810249684892
“Connectome-constrained networks produce a smooth circular direction geometry that random networks cannot replicate”
“The core finding — that behavioral fidelity does not imply representational fidelity — extends the cautionary tale of Brunton et al. (Brunton et al., 2026) in a complementary direction. Where they showed that a worm connectome trained with deep reinforcement learning produces realistic fly walking, we show that a stability-constrained random network with the same architecture cannot
replicate the connectome’s representational geometry even when its behavioral output is functionally equivalent.” -
The lab of Xiaotang Lu is hiring, at University of Illinois. From her lab's webpage:
«Three Postdoc positions are immediately open
a) Biochemistry: experience in protein engineering, molecular probe design, preparation, and the application of advanced imaging platforms to complex tissue samples.
b) Neurobiology: experience in systems neuroscience, circuit neuroscience, and related diseases.
c) Computational science: experience in large imaging data segmentation and analysis, and/or computational protein design.»
https://neurolab.chemistry.illinois.edu/recruit
See also her research page, on the chemistry of #connectomics
https://neurolab.chemistry.illinois.edu/research -
📰 "Uncovering Sex Differences in the Drosophila Ventral Nerve Cord Through Connectome Alignment"
https://www.biorxiv.org/content/10.64898/2026.06.14.732053v1?rss=1
#Connectomics
#Drosophila -
A complete connectome is a highly detailed, three-dimensional wiring diagram mapping all neural connections between the brain and the nerve cord (the spinal cord equivalent) of an adult fruit fly. This comprehensive map allows scientists to observe all neurons and their synaptic connections as a single, holistic functional unit.
#Neuroscience #Neurobiology #Connectomics #ComputationalBiology #sflorg
https://www.sflorg.com/2026/06/ns06092601.html -
2+2 years position for a software engineer / data scientist with serious programming chops in my lab at the #MRCLMB to develop tech for #connectomics and #neuroscience :
Please do share with suitable candidates, and feel free to reach out via email to discuss details.
Deadline for application: May 10th.
Starting date: any within 2026.
Requires Masters plus industry experience, or a PhD in a suitable field – and demonstrable experience in software engineering.
Please help disseminate – either here or by copy-pasting onto emails or messages. Thank you!
#PhDJobs #neuroscience #SoftwareEngineering #jobs #ScienceJobs
-
If interested in this topic, Prof. Bing Brunton gave a talk at #Cosyne2026 which is very much worth watching:
https://youtu.be/yhUBq5R01qA?t=3430
Among other topics, Bing presents the minimal network for the oscillatory behaviour that sustains walking, and also the embodiment of a connectome by plugging it into a virtual mechanical model of the fly, #MuJoCo from the #AnyBrain #HHMIJanelia project team.
-
Postdoc position: Career Returner Fellowship
"The LMB is proud to launch a three-year fully funded fellowship for scientists who have had a career break of 12 months or more."
"At the LMB, we understand that stepping away from research – even briefly – can affect career progression. That is why we have created a dedicated postdoctoral fellowship to support researchers who have taken a career break of 12 months or more, for any reason, for example parental leave, health reasons, caregiving, a career change or other personal circumstances."
https://mrclmb.ac.uk/careers-and-people/postdocs/career-returner-fellowship/
Happy to discuss applications to our lab in #Drosophila #connectomics, #ElectronMicroscopy or #ComputerVision applied to #BioimageInformatics.
-
Shawn Mikula's https://connectomes.org/ doesn't load, but the domain name is registered. Does anyone know who is maintaining the site?
-
Now out as a version of record:
"Neural connectome of the ctenophore statocyst", Jokura et sl. 2026 (Jékely lab)
-
By the way, unlike what the piece says, Murrhy and Seung did NOT "have the idea to use those images to identify and map the connections between each visible neuron, creating a connectome".
That idea had been floating about the field since Brenner and his C. elegans connectome, and those in a position to execute were the groups at Janelia with discretionary HHMI finding, like Rubin, Bock and myself. And we did.
What the Seung lab did was capitalise on the published EM volume of the adult female fly brain to apply more effective image registration and neuron segmentation approaches than the ones tried so far at that point by the Fly EM Project Team at Janelia. Synapses were detected by Julia Buhmann in saalfeld's lab at Janelia as well. The research groups led by Seung, Jefferis (at MRC LMB) and Murthy then put in the gargantuan effort of proofreading to deliver the published connectome.
-
Sunday slow rereading on #neuroscience #drosophila #flybrain #electromicroscopy #connectomics #omics
Holy Molly forgot this top notch quotation!?
,There is a before and after connectome—B.C. and A.C.’
@albertcardona referencing a well-known quote from #columbiaun #TheoreticalNeuroscience Larry Abbott
with this follow-up:
,It’s the end of the beginning’
https://www.science.org/content/article/complete-map-fruit-fly-brain-circuitry-unveiled
-
We are hiring! SPecifically, a PostDoc for data management and connectomics as part of a large clinical research group. The details can be found here: https://www.linkedin.com/posts/epiconn_open-position-apply-now-the-epiconn-activity-7413211951125688320-Wqi5
Please apply if you are interested in up to four years in Vienna, one of the most liveable cities in the world!
#university #medicaluniversityofvienna
#research #vienna #austria #ismrm #mri #7Tesla #epilepsy #connectomics #data_management -
Can neuroscientists decode memories solely from a map of synaptic connections?
| Five experts discuss the progress, possibilities and hurdles of decoding a “nontrivial” memory from an organism just by analyzing its brain connectivity patterns |
The Transmitter: Neuroscience News and Perspectives
🎧🤷
https://www.thetransmitter.org/brain-inspired/can-neuroscientists-decode-memories-solely-from-a-map-of-synaptic-connections/