#mitochondria — Public Fediverse posts

#MetabolicHealth #Mitochondria #EnergyBoost #HealthTips #NutritionMatters #ModernLifestyle #WellnessJourney #HealthyLiving #wellnessthatworks #wellnessblogger #emotionalwellbeing #wellnesslifestyle #wellnesswarrior #healthandwellbeing #CellularEnergy #Vitality https://mastodon.social/@biohackingpathway/117141011274459244

More and more recognition that mitochondria matter an awful lot:

"Brain mitochondria as key drivers of cognition and behaviour", Carmen Sandi et al. 2026, a review.
https://www.nature.com/articles/s41583-026-01061-1

#neuroscience #mitochondria

📰 "Therapeutic potential of the Nrf2 activator omaveloxolone in spinocerebellar ataxia type 3 in cellular and Drosophila models"
https://doi.org/doi:10.3389/fphar.2026.1872142
https://pubmed.ncbi.nlm.nih.gov/42621215/
#Mitochondria #Drosophila

📰 "Ringer Loss in Drosophila Uncovers Mitochondrial Complex I Deficits Characteristic of Human Parkinson's Disease"
https://doi.org/doi:10.64898/2026.07.27.741040
https://pubmed.ncbi.nlm.nih.gov/42619695/
#Mitochondria #Drosophila

📰 "NADH FLIM reveals cellular bioenergetics and mitochondrial morphology during Drosophila convergent extension"
https://doi.org/doi:10.1016/j.ydbio.2026.08.011
https://pubmed.ncbi.nlm.nih.gov/42617721/
#Mitochondria #Drosophila #Germband #Embryo

📰 "Developmental susceptibility to PFOS toxicity in Drosophila shows genetic variation in toxicodynamics and rescue via enhanced muscle mitochondrial function"
https://doi.org/doi:10.1093/toxsci/kfag102
https://pubmed.ncbi.nlm.nih.gov/42615982/
#DrosophilaMelanogaster
#Mitochondria #Drosophila

📰 "Deficiency in MICOS component Chchd3 Compromises Drosophila Heart Function via mitophagy, ROS and ER Stress"
https://www.biorxiv.org/content/10.64898/2026.08.14.744045v1?rss=1
#Mitochondria #Drosophila

The Shocking Truth About Sugar & Energy 😮⁣
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#sugar #energy #dopamine #healthtips #nutrition #mitochondria #sugarfacts #wellness #healthychoices #sciencefacts #healthyliving #foodscience #shorts #shortsvideo ⁣

📰 "Role of Early-Life Microbiome Colonization in Physiological Development of Drosophila melanogaster"
https://www.biorxiv.org/content/10.64898/2026.08.16.745128v1?rss=1
#DrosophilaMelanogaster
#Mitochondria #Drosophila #Metabolism #Immunity #Adult
#Embryo #Larva

📰 "Subarctic Drosophila species cold-acclimated in laboratory maintain full capacity for oxygen consumption in their flight muscle mitochondria"
https://doi.org/doi:10.1016/j.jinsphys.2026.105045
https://pubmed.ncbi.nlm.nih.gov/42603585/
#Mitochondria #Drosophila #Metabolism

🧬 New publication from the lab! 🎉

Timeless and mitochondria! 🧬⚡

Kalisse Horne, a PhD student, started this as a side project, and it grew into a full research project!
Many students in the lab, including Havya, Shriya, and Rhea, also contributed to this work, together with Chiaki Noguchi, Dr. Christian Sell, and Dr. Josh Mell 😊
Great teamwork! 👏🔬

https://www.mdpi.com/2218-273X/16/8/1177

#Timeless #Mitochondria #GenomeIntegrity #ReplicationStress #GraduateSchool #BiomedicalScience #Publication

Probiotics may help protect against sarcopenia in older adults

Researchers used three approaches to study whether probiotics could help prevent sarcopenia (age-related loss of muscle mass, strength…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Nutrition #3dimensional #3D #cellbiology #cristae #cytological #cytology #energy #eukaryotic #Health #HumanBiology #Intracellular #Mitochondria #organelle #respiration
https://www.newsbeep.com/us/812287/

Probiotics may help protect against sarcopenia in older adults

Researchers used three approaches to study whether probiotics could help prevent sarcopenia (age-related loss of muscle mass, str…
#dining #cooking #diet #food #Nutrition #3dimensional #3D #CellBiology #cristae #cytological #cytology #energy #eukaryotic #humanbiology #Intracellular #Mitochondria #nutrition #organelle #respiration
https://www.diningandcooking.com/2768721/probiotics-may-help-protect-against-sarcopenia-in-older-adults/

Probiotics may help protect against sarcopenia in older adults https://www.diningandcooking.com/2768721/probiotics-may-help-protect-against-sarcopenia-in-older-adults/ #3Dimensional #3D #CellBiology #cristae #cytological #cytology #energy #eukaryotic #HumanBiology #Intracellular #Mitochondria #nutrition #organelle #respiration

📰 "Glioblastoma as Developmental Stress Boundary Displacement: Insect Embryonic Cells as Quantitative Reference Platforms for Mitochondrial Adaptation-A Conceptual Framework"
https://doi.org/doi:10.3390/cells15151352
https://pubmed.ncbi.nlm.nih.gov/42587762/
#DrosophilaMelanogaster
#Mitochondria #Drosophila #Embryo

📰 "Machine learning-guided spectral fingerprinting reveals Parkinson's disease-associated biochemical changes in Drosophila melanogaster"
https://doi.org/doi:10.1016/j.saa.2026.128563
https://pubmed.ncbi.nlm.nih.gov/42585923/
#DrosophilaMelanogaster
#Mitochondria #Metabolism #Drosophila

📰 "Monitoring Fatty Acid Trafficking during Drosophila oogenesis Reveals a Role for the Triglyceride Synthase DGAT1 in Protecting Mitochondrial Integrity"
https://www.biorxiv.org/content/10.64898/2026.08.10.743872v1?rss=1
#DrosophilaMelanogaster
#Mitochondria #Drosophila #Metabolism

📰 "Correction: Generation and characterization of germline-specific autophagy and mitochondrial reactive oxygen species reporters in Drosophila"
https://doi.org/doi:10.3389/fcell.2026.1900126
https://pubmed.ncbi.nlm.nih.gov/42583455/
#Mitochondria #Drosophila

📰 "Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila"
https://doi.org/doi:10.1002/1873-3468.70427
https://pubmed.ncbi.nlm.nih.gov/42572502/
#Mitochondria #Drosophila #Metabolism #Genomics #Larva

📰 "Design, synthesis, and evaluation of pyrano[3,2-c]coumarin derivatives for simultaneous targeting of amyloid-beta(42) and acetylcholinesterase in transgenic AD model of Drosophila"
https://doi.org/doi:10.1039/d6ra01662f
https://pubmed.ncbi.nlm.nih.gov/42553843/
#Mitochondria #Drosophila

📰 "Phosphatidylserine synthesis tunes IP3R-mediated ER Ca2+ release via phospholipid homeostasis"
https://doi.org/doi:10.1016/j.celrep.2026.117792
https://pubmed.ncbi.nlm.nih.gov/42550687/
#Mitochondria #Drosophila #Metabolism

📰 "Loss of LipT2 disrupts mitochondrial protein lipoylation and metabolic homeostasis in Drosophila melanogaster"
https://doi.org/doi:10.1002/1873-3468.70422
https://pubmed.ncbi.nlm.nih.gov/42528155/
#DrosophilaMelanogaster
#Mitochondria #Drosophila #Metabolism

📰 "Limiting intestinal iron absorption rescues glial defects and extends lifespan in a Drosophila model of Friedreich's ataxia"
https://doi.org/doi:10.1016/j.nbd.2026.107550
https://pubmed.ncbi.nlm.nih.gov/42526774/
#Mitochondria #Drosophila

DATE: August 6, 2026 at 11:00AM
SOURCE: STAT NEWS NEUROSCIENCE

TITLE: STAT+: Study reveals new role for tau, a top target for Alzheimer’s drug development

URL: https://www.statnews.com/2026/08/06/research-finds-how-tau-targets-cells-structure-alzheimers-drug-development/?utm_campaign=rss

In the race for new ways to treat Alzheimer’s and other devastating neurologic diseases, the protein tau has become a tantalizing target for drug developers. A new study lends support to those efforts by describing a previously unknown role that tau plays in neurodegeneration — and suggesting a novel way researchers might block the protein’s activity.

A team led by Stanford scientists found that tau can gum up the works of a cell’s mitochondria, its energy-producing powerhouse. The protein sends electrons flowing in the opposite direction of their usual microscopic relay race, a reversal that generates reactive oxygen species, cellular stress, and inflammation. Scientists found that blocking this phenomenon, known as reverse electron transport, reversed many of the harmful effects and improved learning and memory in flies and mice.

Whether the same will hold true in people is for now unclear, though an analysis of human cells grown in the lab and patient brain tissue suggests blocking the retrograde flow of electrons could make neurons healthier. Two of the study’s authors have started a biotech startup to put this idea to the test. 

Continue to STAT+ to read the full story…

URL: https://www.statnews.com/2026/08/06/research-finds-how-tau-targets-cells-structure-alzheimers-drug-development/?utm_campaign=rss

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#psychology #counseling #socialwork #psychotherapy @psychotherapist @psychotherapists @psychology @socialpsych @socialwork @psychiatry #mentalhealth #psychiatry #healthcare #depression #psychotherapist #TauProtein #AlzheimersResearch #Neurodegeneration #Mitochondria #ReverseElectronTransport #DrugDevelopment #NeuronsHealth #STANFORDResearch #BiotechStartups #RNAandCellBiology

Something I didn't know until recently about mitochondria is that different cells have different types of them, and there are multiple types of them. That makes me think of cellular evolution a bit differently.

Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC10427836/pdf/nihms-1921885.pdf

#mitochondria #metabolics

Polyphenol-rich extra-virgin olive oil influences bioenergetics and may modulate NLRP3 inflammasome in PBMCs from children and adolescents with obesity https://www.diningandcooking.com/2753832/polyphenol-rich-extra-virgin-olive-oil-influences-bioenergetics-and-may-modulate-nlrp3-inflammasome-in-pbmcs-from-children-and-adolescents-with-obesity/ #biochemistry #CellBiology #ChildrenObesity #diseases #Endocrinology #ExtraVirginOliveOil #HumanitiesAndSocialSciences #Inflammasome #MedicalResearch #Mediterranean #MediterraneanOliveOil #Mitochondria #multidisciplinary #NLRP3 #Olive #OliveOil #PBMCs #physiology #polyphenols #science

Mealybugs' missing mitochondrial genes aren't missing after all, rather, they are tucked in on the opposite DNA strand running the other way. This sort of trickery I only knew from viral genomes.

The amount of genes we may have missed in existing genomes might be a scarily large number. Reminded of the human Y chromosome story, that started at only 3 genes ca. year 2000 and now is already at over 300.

Press release:
https://news.asu.edu/20260611-science-and-technology-new-twist-dna

"Expression of four mitochondrial tRNAs from only two loci", Warren et al. 2026
https://www.pnas.org/doi/10.1073/pnas.2534946123

#genomics #mitochondria #entomology #mealybugs

Heart Rate Zone 2 Magic
Staying in Zone 2 cardio for optimal mitochondrial health and fat oxidation. A brisk walk where you can talk but not sing is the sweet spot.
Drop a 🔥 if you love high-yield, low-stress workouts!
#Zone2Training #MetabolicHealth #Mitochondria

From Tanzania to the lab: hunting with hunter-gatherers reveals how periods of feast and famine can actually trigger a system of conservation & repair.

Follow @biohackingpathway for more

#HunterGatherer #Tanzania #FastingBenefits #CellularRepair #Mitochondria #BloodSugarControl #InflammationReduction #WellnessJourney