#eukaryotic — Public Fediverse posts

Probiotics may help protect against sarcopenia in older adults

Researchers used three approaches to study whether probiotics could help prevent sarcopenia (age-related loss of muscle mass, strength…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Nutrition #3dimensional #3D #cellbiology #cristae #cytological #cytology #energy #eukaryotic #Health #HumanBiology #Intracellular #Mitochondria #organelle #respiration
https://www.newsbeep.com/us/812287/

Probiotics may help protect against sarcopenia in older adults

Researchers used three approaches to study whether probiotics could help prevent sarcopenia (age-related loss of muscle mass, strength…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Nutrition #3dimensional #3D #cellbiology #cristae #cytological #cytology #energy #eukaryotic #Health #HumanBiology #Intracellular #Mitochondria #organelle #respiration
https://www.newsbeep.com/us/812287/

Probiotics may help protect against sarcopenia in older adults

Researchers used three approaches to study whether probiotics could help prevent sarcopenia (age-related loss of muscle mass, str…
#dining #cooking #diet #food #Nutrition #3dimensional #3D #CellBiology #cristae #cytological #cytology #energy #eukaryotic #humanbiology #Intracellular #Mitochondria #nutrition #organelle #respiration
https://www.diningandcooking.com/2768721/probiotics-may-help-protect-against-sarcopenia-in-older-adults/

Probiotics may help protect against sarcopenia in older adults

Researchers used three approaches to study whether probiotics could help prevent sarcopenia (age-related loss of muscle mass, str…
#dining #cooking #diet #food #Nutrition #3dimensional #3D #CellBiology #cristae #cytological #cytology #energy #eukaryotic #humanbiology #Intracellular #Mitochondria #nutrition #organelle #respiration
https://www.diningandcooking.com/2768721/probiotics-may-help-protect-against-sarcopenia-in-older-adults/

Probiotics may help protect against sarcopenia in older adults

Researchers used three approaches to study whether probiotics could help prevent sarcopenia (age-related loss of muscle mass, str…
#dining #cooking #diet #food #Nutrition #3dimensional #3D #CellBiology #cristae #cytological #cytology #energy #eukaryotic #humanbiology #Intracellular #Mitochondria #nutrition #organelle #respiration
https://www.diningandcooking.com/2768721/probiotics-may-help-protect-against-sarcopenia-in-older-adults/

Probiotics may help protect against sarcopenia in older adults https://www.diningandcooking.com/2768721/probiotics-may-help-protect-against-sarcopenia-in-older-adults/ #3Dimensional #3D #CellBiology #cristae #cytological #cytology #energy #eukaryotic #HumanBiology #Intracellular #Mitochondria #nutrition #organelle #respiration

Probiotics may help protect against sarcopenia in older adults https://www.diningandcooking.com/2768721/probiotics-may-help-protect-against-sarcopenia-in-older-adults/ #3Dimensional #3D #CellBiology #cristae #cytological #cytology #energy #eukaryotic #HumanBiology #Intracellular #Mitochondria #nutrition #organelle #respiration

https://www.europesays.com/uk/1146035/ Probiotics may help protect against sarcopenia in older adults #3Dimensional #3D #CellBiology #cristae #cytological #Cytology #Energy #eukaryotic #Health #HumanBiology #intracellular #mitochondria #Nutrition #organelle #Respiration #UK #UnitedKingdom

https://www.theguardian.com/environment/2026/apr/14/african-scientists-fungal-conservation-movement-aoe. The #biosphere is fully integrated & inter-dependent. Take out one part of an #ecosystem & the rest of it collapses - & the same is true of the biosphere as a whole. If all #fungi were to become #extinct, the #extinction of other #eukaryotic life-forms, including #humans, would follow, & very rapidly.

https://www.theguardian.com/environment/2026/apr/14/african-scientists-fungal-conservation-movement-aoe. The #biosphere is fully integrated & inter-dependent. Take out one part of an #ecosystem & the rest of it collapses - & the same is true of the biosphere as a whole. If all #fungi were to become #extinct, the #extinction of other #eukaryotic life-forms, including #humans, would follow, & very rapidly.

https://www.theguardian.com/environment/2026/apr/14/african-scientists-fungal-conservation-movement-aoe. The #biosphere is fully integrated & inter-dependent. Take out one part of an #ecosystem & the rest of it collapses - & the same is true of the biosphere as a whole. If all #fungi were to become #extinct, the #extinction of other #eukaryotic life-forms, including #humans, would follow, & very rapidly.

https://www.theguardian.com/environment/2026/apr/14/african-scientists-fungal-conservation-movement-aoe. The #biosphere is fully integrated & inter-dependent. Take out one part of an #ecosystem & the rest of it collapses - & the same is true of the biosphere as a whole. If all #fungi were to become #extinct, the #extinction of other #eukaryotic life-forms, including #humans, would follow, & very rapidly.

#eukaryotic cells and the proto-ancient Halls Of #Asgard and #FirstContact

*The Conversation* has an interesting read about how #Stromatolites may demonstrate a mechanism for the evolution of Eucaryotic cells like those that make up you or possibly me.[1][2]

https://theconversation.com/first-contact-that-may-have-led-to-complex-life-on-earth-finally-witnessed-by-scientists-280173

https://www.cell.com/current-biology/fulltext/S0960-9822(26)00330-1

The First Contact is actually literal.
Perhaps it's "First" and perhaps that's just __enthusiastic titling__ :)

#Evolution is a thing.
So are Stromatolites::

https://www.sharkbay.org/publications/fact-sheets-guides/stromatolites

"" Nerearchaeum marumarumayae. The species name – marumarumayae – is derived from the Aboriginal language of the Malgana people, meaning “ancient home”, a reference to stromatolites being of ancient origin in Earth’s history. ""

[1] For NON AI versions of consciousness.
[2] I checked Tea and Chilli are Eucaryotic so ... Me too.
https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/General_Biology_(Boundless)/04%3A_Cell_Structure/4.06%3A_Eukaryotic_Cells_-_Characteristics_of_Eukaryotic_Cells

#Biology #Science #Gathaagudu #SharkBay #Bermuda #EarthsLivingRocks

#eukaryotic cells and the proto-ancient Halls Of #Asgard and #FirstContact

*The Conversation* has an interesting read about how #Stromatolites may demonstrate a mechanism for the evolution of Eucaryotic cells like those that make up you or possibly me.[1][2]

https://theconversation.com/first-contact-that-may-have-led-to-complex-life-on-earth-finally-witnessed-by-scientists-280173

https://www.cell.com/current-biology/fulltext/S0960-9822(26)00330-1

The First Contact is actually literal.
Perhaps it's "First" and perhaps that's just __enthusiastic titling__ :)

#Evolution is a thing.
So are Stromatolites::

https://www.sharkbay.org/publications/fact-sheets-guides/stromatolites

"" Nerearchaeum marumarumayae. The species name – marumarumayae – is derived from the Aboriginal language of the Malgana people, meaning “ancient home”, a reference to stromatolites being of ancient origin in Earth’s history. ""

[1] For NON AI versions of consciousness.
[2] I checked Tea and Chilli are Eucaryotic so ... Me too.
https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/General_Biology_(Boundless)/04%3A_Cell_Structure/4.06%3A_Eukaryotic_Cells_-_Characteristics_of_Eukaryotic_Cells

#Biology #Science #Gathaagudu #SharkBay #Bermuda #EarthsLivingRocks

#eukaryotic cells and the proto-ancient Halls Of #Asgard and #FirstContact

*The Conversation* has an interesting read about how #Stromatolites may demonstrate a mechanism for the evolution of Eucaryotic cells like those that make up you or possibly me.[1][2]

https://theconversation.com/first-contact-that-may-have-led-to-complex-life-on-earth-finally-witnessed-by-scientists-280173

https://www.cell.com/current-biology/fulltext/S0960-9822(26)00330-1

The First Contact is actually literal.
Perhaps it's "First" and perhaps that's just __enthusiastic titling__ :)

#Evolution is a thing.
So are Stromatolites::

https://www.sharkbay.org/publications/fact-sheets-guides/stromatolites

"" Nerearchaeum marumarumayae. The species name – marumarumayae – is derived from the Aboriginal language of the Malgana people, meaning “ancient home”, a reference to stromatolites being of ancient origin in Earth’s history. ""

[1] For NON AI versions of consciousness.
[2] I checked Tea and Chilli are Eucaryotic so ... Me too.
https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/General_Biology_(Boundless)/04%3A_Cell_Structure/4.06%3A_Eukaryotic_Cells_-_Characteristics_of_Eukaryotic_Cells

#Biology #Science #Gathaagudu #SharkBay #Bermuda #EarthsLivingRocks

#eukaryotic cells and the proto-ancient Halls Of #Asgard and #FirstContact

*The Conversation* has an interesting read about how #Stromatolites may demonstrate a mechanism for the evolution of Eucaryotic cells like those that make up you or possibly me.[1][2]

https://theconversation.com/first-contact-that-may-have-led-to-complex-life-on-earth-finally-witnessed-by-scientists-280173

https://www.cell.com/current-biology/fulltext/S0960-9822(26)00330-1

The First Contact is actually literal.
Perhaps it's "First" and perhaps that's just __enthusiastic titling__ :)

#Evolution is a thing.
So are Stromatolites::

https://www.sharkbay.org/publications/fact-sheets-guides/stromatolites

"" Nerearchaeum marumarumayae. The species name – marumarumayae – is derived from the Aboriginal language of the Malgana people, meaning “ancient home”, a reference to stromatolites being of ancient origin in Earth’s history. ""

[1] For NON AI versions of consciousness.
[2] I checked Tea and Chilli are Eucaryotic so ... Me too.
https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/General_Biology_(Boundless)/04%3A_Cell_Structure/4.06%3A_Eukaryotic_Cells_-_Characteristics_of_Eukaryotic_Cells

#Biology #Science #Gathaagudu #SharkBay #Bermuda #EarthsLivingRocks

The #eukaryotic OMEGA-Fanzor system allows for precise and efficient #genome #editing due to its compact size and lower collateral activity, but its use in #plants has been limited-until now! Read the latest findings in this #FreeAccess Brief Communication!
https://doi.org/10.1111/jipb.70049
@WileyLifeSci
#PlantScience #JIPB #botany

The #eukaryotic OMEGA-Fanzor system allows for precise and efficient #genome #editing due to its compact size and lower collateral activity, but its use in #plants has been limited-until now! Read the latest findings in this #FreeAccess Brief Communication!
https://doi.org/10.1111/jipb.70049
@WileyLifeSci
#PlantScience #JIPB #botany

The #mitochondrion represents a #biological singularity, a discrete #evolutionary event that fundamentally partitioned life on #Earth into two distinct energetic stratums: the #prokaryotic and the #eukaryotic. While colloquially reduced to the moniker of "cellular powerhouse," the mitochondrion is, in functional reality, a highly integrated endosymbiont that serves as the master regulator of eukaryotic physiology
#WhatIs #Biology #Biochemistry #MolecularBiology #sflorg
https://www.sflorg.com/2025/11/wi11222501.html

The #mitochondrion represents a #biological singularity, a discrete #evolutionary event that fundamentally partitioned life on #Earth into two distinct energetic stratums: the #prokaryotic and the #eukaryotic. While colloquially reduced to the moniker of "cellular powerhouse," the mitochondrion is, in functional reality, a highly integrated endosymbiont that serves as the master regulator of eukaryotic physiology
#WhatIs #Biology #Biochemistry #MolecularBiology #sflorg
https://www.sflorg.com/2025/11/wi11222501.html

The #mitochondrion represents a #biological singularity, a discrete #evolutionary event that fundamentally partitioned life on #Earth into two distinct energetic stratums: the #prokaryotic and the #eukaryotic. While colloquially reduced to the moniker of "cellular powerhouse," the mitochondrion is, in functional reality, a highly integrated endosymbiont that serves as the master regulator of eukaryotic physiology
#WhatIs #Biology #Biochemistry #MolecularBiology #sflorg
https://www.sflorg.com/2025/11/wi11222501.html

The #mitochondrion represents a #biological singularity, a discrete #evolutionary event that fundamentally partitioned life on #Earth into two distinct energetic stratums: the #prokaryotic and the #eukaryotic. While colloquially reduced to the moniker of "cellular powerhouse," the mitochondrion is, in functional reality, a highly integrated endosymbiont that serves as the master regulator of eukaryotic physiology
#WhatIs #Biology #Biochemistry #MolecularBiology #sflorg
https://www.sflorg.com/2025/11/wi11222501.html

Mid-Proterozoic Expansion Of Passive Margins And Reduction In Volcanic Outgassing Supported Marine Oxygenation And Eukaryogenesis
--
https://doi.org/10.1016/j.epsl.2025.119683 <-- shared paper
--
https://zenodo.org/records/17353904 <-- supplementary data
--
#proterozoic #platetectonics #tectonics #deepcarboncycle #eukaryogenesis #evolutionoflife #life #evolution #geology #geologichistory #pangea #supercontinent #diversification #volcanic #offgassing #marine #thermodynamics #model #modeling #spatialanalysis #spatiotemporal #nuna #subduction #structuralgeology #CO2 #carbondioxide #climate #eukaryotic #BoringBillion #rodinia #oceanbasins #marinechemistry #outgassing #global #earth

Mid-Proterozoic Expansion Of Passive Margins And Reduction In Volcanic Outgassing Supported Marine Oxygenation And Eukaryogenesis
--
https://doi.org/10.1016/j.epsl.2025.119683 <-- shared paper
--
https://zenodo.org/records/17353904 <-- supplementary data
--
#proterozoic #platetectonics #tectonics #deepcarboncycle #eukaryogenesis #evolutionoflife #life #evolution #geology #geologichistory #pangea #supercontinent #diversification #volcanic #offgassing #marine #thermodynamics #model #modeling #spatialanalysis #spatiotemporal #nuna #subduction #structuralgeology #CO2 #carbondioxide #climate #eukaryotic #BoringBillion #rodinia #oceanbasins #marinechemistry #outgassing #global #earth

Mid-Proterozoic Expansion Of Passive Margins And Reduction In Volcanic Outgassing Supported Marine Oxygenation And Eukaryogenesis
--
https://doi.org/10.1016/j.epsl.2025.119683 <-- shared paper
--
https://zenodo.org/records/17353904 <-- supplementary data
--
#proterozoic #platetectonics #tectonics #deepcarboncycle #eukaryogenesis #evolutionoflife #life #evolution #geology #geologichistory #pangea #supercontinent #diversification #volcanic #offgassing #marine #thermodynamics #model #modeling #spatialanalysis #spatiotemporal #nuna #subduction #structuralgeology #CO2 #carbondioxide #climate #eukaryotic #BoringBillion #rodinia #oceanbasins #marinechemistry #outgassing #global #earth

Mid-Proterozoic Expansion Of Passive Margins And Reduction In Volcanic Outgassing Supported Marine Oxygenation And Eukaryogenesis
--
https://doi.org/10.1016/j.epsl.2025.119683 <-- shared paper
--
https://zenodo.org/records/17353904 <-- supplementary data
--
#proterozoic #platetectonics #tectonics #deepcarboncycle #eukaryogenesis #evolutionoflife #life #evolution #geology #geologichistory #pangea #supercontinent #diversification #volcanic #offgassing #marine #thermodynamics #model #modeling #spatialanalysis #spatiotemporal #nuna #subduction #structuralgeology #CO2 #carbondioxide #climate #eukaryotic #BoringBillion #rodinia #oceanbasins #marinechemistry #outgassing #global #earth

@lemon

#ALTTEXT from #Mushroom #Fungi picture:

"Fungi challenge us to rethink neat categories around the individual, but they are not the only ones. Another boundary-defying organism is the Slime Mold. These unicellular eukaryotic organisms have the astonishing capacity to join and become a complex multicellular organism. Slime Molds will merge and move as a collective which allows them to better respond to their shifting environments, search for food, and have sex. In a world that feels increasingly precarious, there are lessons here. Devin Cohen, one of the Hanky Project artists, writes that for them, Slime Molds reflect the possibilities for queer communities to work collectively, dissemble the refuse of our human world -- capitalism, environmental waste, cis-hetero-patriarchy, racism -- and 'digest it into something life giving, healed, welcoming and weird.' In a country where toxic individualism has wreaked havoc, where mantras like 'pull yourself up by the bootstraps,' are presented as means for 'success,' organisms that choose to come together present a radical and refreshing alternative."

- #Quote from the book:
Exuberant Possibilities : Queer Ecology Hanky Project

Photo is of pages 18 and 19 of the book as displayed during the exhibit, Earth Archives. the page is typed in light purple text. the page is illustrated with a blue-green block print of a mushroom centaur holding a crystal staff .. many blue-green block print #honey mushrooms also decorate the page.

#Mold Molds #Alternative #eukaryotic #multicellular #centaur

@lemon

#ALTTEXT from #Mushroom #Fungi picture:

"Fungi challenge us to rethink neat categories around the individual, but they are not the only ones. Another boundary-defying organism is the Slime Mold. These unicellular eukaryotic organisms have the astonishing capacity to join and become a complex multicellular organism. Slime Molds will merge and move as a collective which allows them to better respond to their shifting environments, search for food, and have sex. In a world that feels increasingly precarious, there are lessons here. Devin Cohen, one of the Hanky Project artists, writes that for them, Slime Molds reflect the possibilities for queer communities to work collectively, dissemble the refuse of our human world -- capitalism, environmental waste, cis-hetero-patriarchy, racism -- and 'digest it into something life giving, healed, welcoming and weird.' In a country where toxic individualism has wreaked havoc, where mantras like 'pull yourself up by the bootstraps,' are presented as means for 'success,' organisms that choose to come together present a radical and refreshing alternative."

- #Quote from the book:
Exuberant Possibilities : Queer Ecology Hanky Project

Photo is of pages 18 and 19 of the book as displayed during the exhibit, Earth Archives. the page is typed in light purple text. the page is illustrated with a blue-green block print of a mushroom centaur holding a crystal staff .. many blue-green block print #honey mushrooms also decorate the page.

#Mold Molds #Alternative #eukaryotic #multicellular #centaur

The eukaryotic cell emerged as an evolutionary algorithmic phase transition / Eukaryogenesis happened abruptly, led by the tension of increasing gene length and the constraints on producing longer proteins / Evolvement of the eukaryotic cell is the most significant increase in complexity in the history of life's evolution on Earth 👉 https://press.uni-mainz.de/eukaryotic-cell-emerged-as-evolutionary-algorithmic-phase-transition/

#EvolutionaryBiology #ComputerBiology #eukaryotic #genes #proteins #evolution #EukaryoticCells #eukaryogenesis #biology #physics

The eukaryotic cell emerged as an evolutionary algorithmic phase transition / Eukaryogenesis happened abruptly, led by the tension of increasing gene length and the constraints on producing longer proteins / Evolvement of the eukaryotic cell is the most significant increase in complexity in the history of life's evolution on Earth 👉 https://press.uni-mainz.de/eukaryotic-cell-emerged-as-evolutionary-algorithmic-phase-transition/

#EvolutionaryBiology #ComputerBiology #eukaryotic #genes #proteins #evolution #EukaryoticCells #eukaryogenesis #biology #physics

The eukaryotic cell emerged as an evolutionary algorithmic phase transition / Eukaryogenesis happened abruptly, led by the tension of increasing gene length and the constraints on producing longer proteins / Evolvement of the eukaryotic cell is the most significant increase in complexity in the history of life's evolution on Earth 👉 https://press.uni-mainz.de/eukaryotic-cell-emerged-as-evolutionary-algorithmic-phase-transition/

#EvolutionaryBiology #ComputerBiology #eukaryotic #genes #proteins #evolution #EukaryoticCells #eukaryogenesis #biology #physics

#Eukaryotic #phytoplankton decline due to #ocean #acidification could significantly impact global #carbon_cycle

#climate_change #mightymicrobes #CO2 #primary_production #carbon_fixation

https://phys.org/news/2025-03-eukaryotic-phytoplankton-decline-due-ocean.html

#Eukaryotic #phytoplankton decline due to #ocean #acidification could significantly impact global #carbon_cycle

#climate_change #mightymicrobes #CO2 #primary_production #carbon_fixation

https://phys.org/news/2025-03-eukaryotic-phytoplankton-decline-due-ocean.html

#Eukaryotic #phytoplankton decline due to #ocean #acidification could significantly impact global #carbon_cycle

#climate_change #mightymicrobes #CO2 #primary_production #carbon_fixation

https://phys.org/news/2025-03-eukaryotic-phytoplankton-decline-due-ocean.html

#Eukaryotic #phytoplankton decline due to #ocean #acidification could significantly impact global #carbon_cycle

#climate_change #mightymicrobes #CO2 #primary_production #carbon_fixation

https://phys.org/news/2025-03-eukaryotic-phytoplankton-decline-due-ocean.html

Prokaryotic single-celled organisms, the ancestors of modern-day #bacteria and #archaea, are the most ancient form of #life on our #planet, first appearing roughly 3.5 billion years ago.

The first #eukaryotic cells appeared around 1–1.5 billion years later.

However, eukaryotic cells have since diversified into many complex, #multicellular organisms that we see around us every day—#fungi, #plants and #animals—while prokaryotes have remained decidedly unicellular.

https://phys.org/news/2024-03-eukaryotes-bacteria-evolved-complex-multicellularity.html#google_vignette

Prokaryotic single-celled organisms, the ancestors of modern-day #bacteria and #archaea, are the most ancient form of #life on our #planet, first appearing roughly 3.5 billion years ago.

The first #eukaryotic cells appeared around 1–1.5 billion years later.

However, eukaryotic cells have since diversified into many complex, #multicellular organisms that we see around us every day—#fungi, #plants and #animals—while prokaryotes have remained decidedly unicellular.

https://phys.org/news/2024-03-eukaryotes-bacteria-evolved-complex-multicellularity.html#google_vignette

Prokaryotic single-celled organisms, the ancestors of modern-day #bacteria and #archaea, are the most ancient form of #life on our #planet, first appearing roughly 3.5 billion years ago.

The first #eukaryotic cells appeared around 1–1.5 billion years later.

However, eukaryotic cells have since diversified into many complex, #multicellular organisms that we see around us every day—#fungi, #plants and #animals—while prokaryotes have remained decidedly unicellular.

https://phys.org/news/2024-03-eukaryotes-bacteria-evolved-complex-multicellularity.html#google_vignette

Prokaryotic single-celled organisms, the ancestors of modern-day #bacteria and #archaea, are the most ancient form of #life on our #planet, first appearing roughly 3.5 billion years ago.

The first #eukaryotic cells appeared around 1–1.5 billion years later.

However, eukaryotic cells have since diversified into many complex, #multicellular organisms that we see around us every day—#fungi, #plants and #animals—while prokaryotes have remained decidedly unicellular.

https://phys.org/news/2024-03-eukaryotes-bacteria-evolved-complex-multicellularity.html#google_vignette

"We identified two anti-CRISPR proteins AcrIC8 and AcrIC9 that strongly inhibit Neisseria lactamica I-C function. Structural analysis showed that AcrIC8 inhibits PAM recognition through allosteric inhibition, whereas AcrIC9 achieves so through direct competition. Both Acrs potently inhibit I-C-mediated genome editing and transcriptional modulation in human cells, providing the first off-switches for type I #CRISPR #eukaryotic #genome #engineering."

https://www.sciencedirect.com/science/article/abs/pii/S1097276523010808?via%3Dihub

"We identified two anti-CRISPR proteins AcrIC8 and AcrIC9 that strongly inhibit Neisseria lactamica I-C function. Structural analysis showed that AcrIC8 inhibits PAM recognition through allosteric inhibition, whereas AcrIC9 achieves so through direct competition. Both Acrs potently inhibit I-C-mediated genome editing and transcriptional modulation in human cells, providing the first off-switches for type I #CRISPR #eukaryotic #genome #engineering."

https://www.sciencedirect.com/science/article/abs/pii/S1097276523010808?via%3Dihub

"We identified two anti-CRISPR proteins AcrIC8 and AcrIC9 that strongly inhibit Neisseria lactamica I-C function. Structural analysis showed that AcrIC8 inhibits PAM recognition through allosteric inhibition, whereas AcrIC9 achieves so through direct competition. Both Acrs potently inhibit I-C-mediated genome editing and transcriptional modulation in human cells, providing the first off-switches for type I #CRISPR #eukaryotic #genome #engineering."

https://www.sciencedirect.com/science/article/abs/pii/S1097276523010808?via%3Dihub

"We identified two anti-CRISPR proteins AcrIC8 and AcrIC9 that strongly inhibit Neisseria lactamica I-C function. Structural analysis showed that AcrIC8 inhibits PAM recognition through allosteric inhibition, whereas AcrIC9 achieves so through direct competition. Both Acrs potently inhibit I-C-mediated genome editing and transcriptional modulation in human cells, providing the first off-switches for type I #CRISPR #eukaryotic #genome #engineering."

https://www.sciencedirect.com/science/article/abs/pii/S1097276523010808?via%3Dihub

Openly available #illustrations as tools to describe #eukaryotic #microbial #diversity

Beautiful and extremely useful #open #resource from Yana Eglit and @pjkeelinglab depicting eukaryotic microbes in exquisite detail.

Aren’t they lovely? Which is your favorite?
@PLOSBiology
#LoveMicrobiology

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002395

Openly available #illustrations as tools to describe #eukaryotic #microbial #diversity

Beautiful and extremely useful #open #resource from Yana Eglit and @pjkeelinglab depicting eukaryotic microbes in exquisite detail.

Aren’t they lovely? Which is your favorite?
@PLOSBiology
#LoveMicrobiology

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002395

Openly available #illustrations as tools to describe #eukaryotic #microbial #diversity

Beautiful and extremely useful #open #resource from Yana Eglit and @pjkeelinglab depicting eukaryotic microbes in exquisite detail.

Aren’t they lovely? Which is your favorite?
@PLOSBiology
#LoveMicrobiology

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002395

Openly available #illustrations as tools to describe #eukaryotic #microbial #diversity

Beautiful and extremely useful #open #resource from Yana Eglit and @pjkeelinglab depicting eukaryotic microbes in exquisite detail.

Aren’t they lovely? Which is your favorite?
@PLOSBiology
#LoveMicrobiology

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002395

How did #eukaryotes evolve for extreme temps? https://www.futurity.org/high-temp-eukaryotes-2972442-2/ #protists

#ExtremeEnvironments offer an unprecedented opportunity to understand #microbial #eukaryotic #ecology, #evolution, and #genome #biology: Hannah Rappaport & Angela Oliverio https://www.nature.com/articles/s41467-023-40657-4

“several lineages of #amoebae were often recovered from extremely high temperature environments. Studying those lineages may yield great insight into how eukaryotic cells can adapt to life in extremely hot environments.”

How did #eukaryotes evolve for extreme temps? https://www.futurity.org/high-temp-eukaryotes-2972442-2/ #protists

#ExtremeEnvironments offer an unprecedented opportunity to understand #microbial #eukaryotic #ecology, #evolution, and #genome #biology: Hannah Rappaport & Angela Oliverio https://www.nature.com/articles/s41467-023-40657-4

“several lineages of #amoebae were often recovered from extremely high temperature environments. Studying those lineages may yield great insight into how eukaryotic cells can adapt to life in extremely hot environments.”

How did #eukaryotes evolve for extreme temps? https://www.futurity.org/high-temp-eukaryotes-2972442-2/ #protists

#ExtremeEnvironments offer an unprecedented opportunity to understand #microbial #eukaryotic #ecology, #evolution, and #genome #biology: Hannah Rappaport & Angela Oliverio https://www.nature.com/articles/s41467-023-40657-4

“several lineages of #amoebae were often recovered from extremely high temperature environments. Studying those lineages may yield great insight into how eukaryotic cells can adapt to life in extremely hot environments.”

How did #eukaryotes evolve for extreme temps? https://www.futurity.org/high-temp-eukaryotes-2972442-2/ #protists

#ExtremeEnvironments offer an unprecedented opportunity to understand #microbial #eukaryotic #ecology, #evolution, and #genome #biology: Hannah Rappaport & Angela Oliverio https://www.nature.com/articles/s41467-023-40657-4

“several lineages of #amoebae were often recovered from extremely high temperature environments. Studying those lineages may yield great insight into how eukaryotic cells can adapt to life in extremely hot environments.”

`We also show that Fz can be reprogrammed for human genome engineering applications. Finally, we resolved the structure of Spizellomyces punctatus Fz (SpuFz) at 2.7Å using cryogenic-electron microscopy, revealing the conservation of the core regions among Fz, TnpB and Cas12, despite diverse cognate #RNA structures. Our results show that Fz is a #eukaryotic OMEGA system, demonstrating that RNA-guided #endonucleases are present in all three domains of #life.`

https://www.nature.com/articles/s41586-023-06356-2

`We also show that Fz can be reprogrammed for human genome engineering applications. Finally, we resolved the structure of Spizellomyces punctatus Fz (SpuFz) at 2.7Å using cryogenic-electron microscopy, revealing the conservation of the core regions among Fz, TnpB and Cas12, despite diverse cognate #RNA structures. Our results show that Fz is a #eukaryotic OMEGA system, demonstrating that RNA-guided #endonucleases are present in all three domains of #life.`

https://www.nature.com/articles/s41586-023-06356-2

`We also show that Fz can be reprogrammed for human genome engineering applications. Finally, we resolved the structure of Spizellomyces punctatus Fz (SpuFz) at 2.7Å using cryogenic-electron microscopy, revealing the conservation of the core regions among Fz, TnpB and Cas12, despite diverse cognate #RNA structures. Our results show that Fz is a #eukaryotic OMEGA system, demonstrating that RNA-guided #endonucleases are present in all three domains of #life.`

https://www.nature.com/articles/s41586-023-06356-2

`We also show that Fz can be reprogrammed for human genome engineering applications. Finally, we resolved the structure of Spizellomyces punctatus Fz (SpuFz) at 2.7Å using cryogenic-electron microscopy, revealing the conservation of the core regions among Fz, TnpB and Cas12, despite diverse cognate #RNA structures. Our results show that Fz is a #eukaryotic OMEGA system, demonstrating that RNA-guided #endonucleases are present in all three domains of #life.`

https://www.nature.com/articles/s41586-023-06356-2

The #cells of living organisms are equipped with #proteins that are involved in the shaping and remodeling of #cellular membranes, thereby performing important tasks. #SynDLP could be a #bacterial ancestor of #eukaryotic membrane proteins.
#Biology #sflorg
https://www.sflorg.com/2023/04/bio04262303.html

The #cells of living organisms are equipped with #proteins that are involved in the shaping and remodeling of #cellular membranes, thereby performing important tasks. #SynDLP could be a #bacterial ancestor of #eukaryotic membrane proteins.
#Biology #sflorg
https://www.sflorg.com/2023/04/bio04262303.html

The #cells of living organisms are equipped with #proteins that are involved in the shaping and remodeling of #cellular membranes, thereby performing important tasks. #SynDLP could be a #bacterial ancestor of #eukaryotic membrane proteins.
#Biology #sflorg
https://www.sflorg.com/2023/04/bio04262303.html

The #cells of living organisms are equipped with #proteins that are involved in the shaping and remodeling of #cellular membranes, thereby performing important tasks. #SynDLP could be a #bacterial ancestor of #eukaryotic membrane proteins.
#Biology #sflorg
https://www.sflorg.com/2023/04/bio04262303.html

Primitive Asgard Cells:

#Asgard #archaea are now among the most coveted organisms in science, and for good reason. To many evolutionary biologists, their discovery and subsequent studies justify revising the textbook pictures of the tree of life to situate us — and every other creature built from #eukaryotic cells — as mere offshoots of the Asgard group

Studies of Asgard genomes, meanwhile, have brought badly needed data to the question of how eukaryotes evolved, an epochal event in Earth’s history that inspires contentious debates.

Most of the studies to date have had to rely on indirect genetic probes of the Asgard group, which don’t offer the same opportunities as prodding living microbes in a lab, the gold standard in microbiology since the days of Louis Pasteur.

Now a high-stakes, slow-motion race is on as labs around the world attempt to #grow their own #Asgard #cultures. Samples aren’t shared; growth strategies are tightly guarded secrets.

“We were honestly shocked” when the Schleper team’s results came out, wrote Hiroyuki Imachi, the microbiologist at the Japan Agency for Marine-Earth Science and Technology who, after a grueling 12-year effort, isolated the #first and currently #only other Asgard archaea sample.

They aren’t the only ones. Thijs Ettema, an evolutionary microbiologist at Wageningen University in the Netherlands, hinted that his lab had made progress toward enriching Asgard cultures too, and he guessed that at least 10 other labs had similar projects underway. “They wouldn’t be telling me,” he said.
https://www.quantamagazine.org/primitive-asgard-cells-show-life-on-the-brink-of-complexity-20230411/