#fmrp — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #fmrp, aggregated by home.social.
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Neurons struggle to spike without fragile X gene
https://www.spectrumnews.org/news/neurons-struggle-to-spike-without-fragile-x-gene/
#fragileXsyndrome #prefrontalcortex #dendrites #autism #cortex #News #FMR1 #FMRP -
Missing mechanism helps solve fragile X protein mystery
https://www.spectrumnews.org/news/missing-mechanism-helps-solve-fragile-x-protein-mystery/
#intellectualdisability #repetitivebehaviors #socialdifficulties #fragileXsyndrome #neuralcircuits #connectivity #hippocampus #mousemodels #treatments #synapses #autism #News #FMR1 #FMRP -
In #Science (@sciencemagazine) this week, the Hanahan lab shows that the #RNA-binding protein #FMRP enables #tumors to evade being attacked by #CD8TCells. It does so by both suppressing #CCL17 & promoting #Tregs via #IL33 & #M2 #macrophages via #PROS1 & #ExtracellularVesicles!
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Fragile X neurons develop atypically in chimeric mice
https://www.spectrumnews.org/news/fragile-x-neurons-develop-atypically-in-chimeric-mice/
#fragileXsyndrome #mousemodels #autism #News #FMR1 #FMRP -
The cloudy connection between fragile X and cancer
https://www.spectrumnews.org/news/the-cloudy-connection-between-fragile-x-and-cancer/
#intellectualdisability #tuberoussclerosis #fragileXsyndrome #autism #cancer #News #FMR1 #FMRP #PTEN #TSC1 -
Largest-yet fragile X mutation in mice confirms model’s shortcomings
https://www.spectrumnews.org/news/largest-yet-fragile-x-mutation-in-mice-confirms-models-shortcomings/
#fragileXsyndrome #geneexpression #epigenetics #mousemodels #autism #News #FMR1 #FMRP -
Plethora of protein-making machines in neurons may underlie fragile X
https://www.spectrumnews.org/news/plethora-of-protein-making-machines-in-neurons-may-underlie-fragile-x/
#synapticplasticity #fragileXsyndrome #geneexpression #hippocampus #mousemodels #SFARIGene #autism #mGluR5 #News #FMR1 #FMRP -
Plethora of protein-making machines in neurons may underlie fragile X
https://www.spectrumnews.org/news/plethora-of-protein-making-machines-in-neurons-may-underlie-fragile-x/
#synapticplasticity #fragileXsyndrome #geneexpression #hippocampus #mousemodels #SFARIGene #autism #mGluR5 #News #FMR1 #FMRP -
Portrait of a research field: astrocytes in autism
https://www.spectrumnews.org/features/deep-dive/portrait-of-a-research-field-astrocytes-in-autism/
#excitatorysignaling #inhibitorysignaling #signalingimbalance #fragileXsyndrome #postmortembrains #geneexpression #Rettsyndrome #environment #mousemodels #astrocytes #organoids #DeepDive #seizures #synapses #autism #MECP2 #FMR1 #FMRP #GABA -
A whisper of autism: Fragile X carriers and the autism phenotype
https://www.spectrumnews.org/opinion/viewpoint/a-whisper-of-autism-fragile-x-carriers-and-the-autism-phenotype/
#fragileXsyndrome #bipolardisorder #genetictesting #endophenotype #aripiprazole #depression #Viewpoint #anxiety #autism #FMR1 #FMRP -
Location prompts fragile X protein to flip its function
https://www.spectrumnews.org/news/location-prompts-fragile-x-protein-to-flip-its-function/
#signalingimbalance #synapticplasticity #learningandmemory #fragileXsyndrome #hippocampus #seizures #synapses #autism #News #FMRP -
Finding a path forward for fragile X drugs
https://www.spectrumnews.org/news/finding-a-path-forward-for-fragile-x-drugs/
#fragileXsyndrome #clinicaltrials #biomarkers #treatments #language #autism #News #FMR1 #FMRP #EEG -
Remembering Steve Warren (1953-2021): A giant in the field of genetics
https://www.spectrumnews.org/opinion/viewpoint/remembering-steve-warren-1953-2021-a-giant-in-the-field-of-genetics/
#spokenversion #Viewpoint #fragileX #autism #FMR1 #FMRP -
Molecular overlap links tuberous sclerosis, fragile X
https://www.spectrumnews.org/news/molecular-overlap-links-tuberous-sclerosis-fragile-x/
#tuberoussclerosis #fragileXsyndrome #geneexpression #spokenversion #cerebellum #rapamycin #News #FMRP #TSC1