#mousemodels — Public Fediverse posts

Research Assistant
Keele University

We are recruiting a Research Assistant to work on an exciting project aimed at defining the role of brown adipose tissue in spinal muscular atrophy.

See the full job description on jobRxiv: https://jobrxiv.org/job/keele-university-27778-research-assistant/

#brownadiposetissue #molecularbiology #mousemodels #Neuromusculardiseases #primarycellculture #spinalmuscularatrophy #Sc...
https://jobrxiv.org/job/keele-university-27778-research-assistant/?fsp_sid=3917

Research Assistant
Keele University

We are recruiting a Research Assistant to work on an exciting project aimed at defining the role of brown adipose tissue in spinal muscular atrophy.

See the full job description on jobRxiv: https://jobrxiv.org/job/keele-university-27778-research-assistant/

#brownadiposetissue #molecularbiology #mousemodels #Neuromusculardiseases #primarycellculture #spinalmuscularatrophy #Sc...
https://jobrxiv.org/job/keele-university-27778-research-assistant/?fsp_sid=3469

Q for my fellow neuroscience peeps. Is there a way to stabilize the expression of cre if its under the control of a promoter that is active only transiently during development?

Is it possible to cross a cre line with a cre-dependent cre-expressing reporter mouse so that cre become permanently expressed in the population of interest, and amenable for e.g. virus injection in the adult?

Are there tried and true solutions?

#AAV #cre #MouseModels #neuroscience

Serotonin initiates earliest social bonds

https://www.spectrumnews.org/news/serotonin-initiates-earliest-social-bonds/

#sensoryperception #neuralcircuits #animalmodels #mousemodels #serotonin #oxytocin #News #rats

Missing mechanism helps solve fragile X protein mystery

https://www.spectrumnews.org/news/missing-mechanism-helps-solve-fragile-x-protein-mystery/

#intellectualdisability #repetitivebehaviors #socialdifficulties #fragileXsyndrome #neuralcircuits #connectivity #hippocampus #mousemodels #treatments #synapses #autism #News #FMR1 #FMRP

Beyond the bench: Finding balance with Gavin Rumbaugh

https://www.spectrumnews.org/opinion/q-and-a/beyond-the-bench-finding-balance-with-gavin-rumbaugh/

#sensoryperception #neuralcircuits #mousemodels #synapses #autism #QA

The link between maternal infection and autism, explained

https://www.spectrumnews.org/news/the-link-between-maternal-infection-and-autism-explained/

#repetitivebehaviors #maternalinfection #neuralcircuits #neuralnetworks #schizophrenia #animalmodels #epidemiology #immunesystem #environment #mousemodels #microbiome #microglia #pregnancy #COVID-19 #placenta #monkeys #autism #News #ADHD #rats

New #colitis study from LJI's Kronenberg Lab: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1034648/full

The team investigated whether increased expression of two GPRs (GPR183 and GPR18) in the intestine is related to disease severity in colitis models.

#Immunology #Tcells #ImmuneSystem #CellularBiology #MolecularBiology #GPRs #infammation #BowelDisease #Health #MouseModels

Autism genes converge on disruptions in social brain circuit

https://www.spectrumnews.org/news/autism-genes-converge-on-disruptions-in-social-brain-circuit/

#excitatorysignaling #inhibitorysignaling #connectivity #mousemodels #autism #News #FMR1 #TSC2

Mouse model reveals root of breathing issues in rare form of autism

https://www.spectrumnews.org/news/mouse-model-reveals-root-of-breathing-issues-in-rare-form-of-autism/

#developmentaldelay #neuralcircuits #hyperactivity #mousemodels #treatments #diagnosis #seizures #autism #News

Precocious neurons may stunt brain growth in rare form of autism

https://www.spectrumnews.org/news/precocious-neurons-may-stunt-brain-growth-in-rare-form-of-autism/

#intellectualdisability #geneexpression #socialdeficits #hyperactivity #brainimaging #microcephaly #rarevariants #mousemodels #autism #News #ADHD