#tumors — Public Fediverse posts

The K+ channel KCNK1 is differentially expressed in many #tumors, but why? Study shows that KCNK1 overexpression in #BreastCancer promotes proliferation, invasion & #metastasis by increasing #glycolysis & activating #LactateDehydrogenase. #PLOSBiology https://plos.io/3VTNdCr

Last talk of the #CSSingleCells23 conference:
Karin Pelka, Gladstone/UCSF
https://pelkalab.org/

Spatially organized #immune hubs in #colon #cancer
#ColonCancer
#scRNAseq

https://pubmed.ncbi.nlm.nih.gov/34450029/

Then: predict cellular interaction networks via correlations of gene program activities across #tumors

anti-tumor hubs in tumors, ISGs including CXCR3 ligands, differs between tumor types (MMR+ or -)

have data from clinical trial (biopsies before and after treatment)
https://pubmed.ncbi.nlm.nih.gov/36702949/

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Cancer Cell Therapy Biotech Launches, Raises $10M

A start-up company with a process for harvesting large quantities of #cells that infiltrate and kill solid #tumors is raising $10 million in seed venture funds.

https://sciencebusiness.technewslit.com/?p=44683

#News #Science #Business #Cancer #Biotechnology #Engineering #CellTherapy #Lymphocyte #Finance #VentureCapital #SeedFunds #StartUp #Magnetic #Microfluidics #Nanotechnology

#HopeIsComing for #cancer #preventing #treatment #bladderCancer in particular
And none too soon

#enzyme #APOBEC3 #tumors #mutations

https://scitechdaily.com/cancers-secret-weapon-enzyme-that-protects-against-viruses-may-fuel-tumor-evolution/

Did you know that during #embryo development, migrating #monocytes deposit tracks of pro-angiogenic #migrasomes guiding the formation of blood vessels?

In this interesting manuscript published in Nature Cell Biology, researchers at Tsinghua University in Beijing studied this phenomenon in the chorioallantoic membrane of chick embryos: https://www.nature.com/articles/s41556-022-01026-3

This could have implications in organotypic #tissueengineering and provide new ways how to inhibit #angiogenesis in solid #tumors.