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#cd8tcells — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #cd8tcells, aggregated by home.social.

  1. A cool experiment on CD8 T cell proliferative expansion and memory.

    Upon adoptive transfer (to a different mouse) "functionally competent T cells can retain the potential for extraordinary population expansion and longevity well beyond their organismal lifespan."
    (at least 10 years!)

    #Tcells #CD8Tcells #Tcellmemory #immunology #immuneresponse #celllongevity #cellproliferation

    "Functional T cells are capable of supernumerary cell division and longevity"

    nature.com/articles/s41586-022

  2. A cool experiment on CD8 T cell proliferative expansion and memory.

    Upon adoptive transfer (to a different mouse) "functionally competent T cells can retain the potential for extraordinary population expansion and longevity well beyond their organismal lifespan."
    (at least 10 years!)

    #Tcells #CD8Tcells #Tcellmemory #immunology #immuneresponse #celllongevity #cellproliferation

    "Functional T cells are capable of supernumerary cell division and longevity"

    nature.com/articles/s41586-022

  3. 'Long-lasting sepsis-induced immunoparalysis has been principally studied in primary (1°) memory CD8 T cells; however, the impact of sepsis on memory CD8 T cells with a history of repeated cognate Ag encounters is largely unknown but important in understanding the role of sepsis in shaping the pre-existing memory CD8 T cell compartment.'

    #immunology #Sepsis #CTL #cd8tcells

    journals.aai.org/jimmunol/arti

  4. In (@sciencemagazine) this week, the Hanahan lab shows that the -binding protein enables to evade being attacked by . It does so by both suppressing & promoting via & via & !

    bit.ly/Sci_abl7207

  5. In #Science (@sciencemagazine) this week, the Hanahan lab shows that the #RNA-binding protein #FMRP enables #tumors to evade being attacked by #CD8TCells. It does so by both suppressing #CCL17 & promoting #Tregs via #IL33 & #M2 #macrophages via #PROS1 & #ExtracellularVesicles!

    bit.ly/Sci_abl7207

    #CancerImmunology #RBP