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#learningandmemory — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #learningandmemory, aggregated by home.social.

  1. "Visceral signaling of post-ingestive malaise directs memory updating in Drosophila", Senapati et al. 2026 (Waddell's lab)

    biorxiv.org/content/10.1101/20

    #neuroscience #Drosophila #LearningAndMemory

    2/2

  2. "Aversive learning hijacks a brain sugar sensor to consolidate memory", Francés et al. 2026 (Preat's and Plaçais' lab).
    nature.com/articles/s41586-026

    "an internal sugar sensor in the Drosophila brain6 is involved in memory consolidation [...] By revealing a mechanism of non-homeostatic hunger and its critical relevance for memory consolidation, our results provide a neural circuit basis, and a cognitive value, to a behaviour akin to emotional eating."

    #neuroscience #Drosophila #LearningAndMemory

  3. @eLife

    “This paper presents fundamental research showing that the acquisition and expression of Pavlovian conditioned responding are lawfully related to temporal characteristics of an animal's conditioning experience. It showcases a rigorous experimental design, several different approaches to data analysis, careful consideration of prior literature, and a thorough introduction. The evidence supporting the conclusions is compelling. The paper will have a general appeal to those interested in the behavioral and neural analysis of Pavlovian conditioning.”

    “Information, certainty, and learning”, Harris and Gallistel, 2026
    elifesciences.org/articles/102

    #neuroscience #learning #LearningAndMemory #rats

  4. "Short-term memory errors are strongly associated with a drift in neural activity in the posterior parietal cortex", Joon Ho Choi et al. 2025 (Jong-Cheol Rah's lab).

    "Using 2-photon calcium imaging in the posterior parietal cortex (PPC) of mice performing a delayed match-to-sample task, we identified a subset of PPC neurons exhibiting both directional and temporal selectivity. Contrary to the hypothesis that STM errors primarily stem from mis-encoding during the sample phase, our findings reveal that these errors are more strongly associated with a drift in neural activity during the delay period. This drift leads to a gradual divergence away from the correct representation, ultimately leading to incorrect behavioral responses."

    #neuroscience #LearningAndMemory #CerebralCortex #STM

  5. "Short-term memory errors are strongly associated with a drift in neural activity in the posterior parietal cortex", Joon Ho Choi et al. 2025 (Jong-Cheol Rah's lab).

    "Using 2-photon calcium imaging in the posterior parietal cortex (PPC) of mice performing a delayed match-to-sample task, we identified a subset of PPC neurons exhibiting both directional and temporal selectivity. Contrary to the hypothesis that STM errors primarily stem from mis-encoding during the sample phase, our findings reveal that these errors are more strongly associated with a drift in neural activity during the delay period. This drift leads to a gradual divergence away from the correct representation, ultimately leading to incorrect behavioral responses."

    #neuroscience #LearningAndMemory #CerebralCortex #STM

  6. "Short-term memory errors are strongly associated with a drift in neural activity in the posterior parietal cortex", Joon Ho Choi et al. 2025 (Jong-Cheol Rah's lab).

    "Using 2-photon calcium imaging in the posterior parietal cortex (PPC) of mice performing a delayed match-to-sample task, we identified a subset of PPC neurons exhibiting both directional and temporal selectivity. Contrary to the hypothesis that STM errors primarily stem from mis-encoding during the sample phase, our findings reveal that these errors are more strongly associated with a drift in neural activity during the delay period. This drift leads to a gradual divergence away from the correct representation, ultimately leading to incorrect behavioral responses."

    #neuroscience #LearningAndMemory #CerebralCortex #STM

  7. "Short-term memory errors are strongly associated with a drift in neural activity in the posterior parietal cortex", Joon Ho Choi et al. 2025 (Jong-Cheol Rah's lab).

    "Using 2-photon calcium imaging in the posterior parietal cortex (PPC) of mice performing a delayed match-to-sample task, we identified a subset of PPC neurons exhibiting both directional and temporal selectivity. Contrary to the hypothesis that STM errors primarily stem from mis-encoding during the sample phase, our findings reveal that these errors are more strongly associated with a drift in neural activity during the delay period. This drift leads to a gradual divergence away from the correct representation, ultimately leading to incorrect behavioral responses."

    #neuroscience #LearningAndMemory #CerebralCortex #STM

  8. "Short-term memory errors are strongly associated with a drift in neural activity in the posterior parietal cortex", Joon Ho Choi et al. 2025 (Jong-Cheol Rah's lab).

    "Using 2-photon calcium imaging in the posterior parietal cortex (PPC) of mice performing a delayed match-to-sample task, we identified a subset of PPC neurons exhibiting both directional and temporal selectivity. Contrary to the hypothesis that STM errors primarily stem from mis-encoding during the sample phase, our findings reveal that these errors are more strongly associated with a drift in neural activity during the delay period. This drift leads to a gradual divergence away from the correct representation, ultimately leading to incorrect behavioral responses."

    #neuroscience #LearningAndMemory #CerebralCortex #STM

  9. "A temporally restricted function of the dopamine receptor Dop1R2 during memory formation", Kaldun et al. 2025 (Sprecher lab).
    elifesciences.org/articles/993

    In Kenyon cells, "loss of dop1R2 from ab or a'b' block the ability of flies to display measurable forms of longer forms of memory"

    In other words, a specific dopamine receptor is now associated with long-term memory in fruit flies, and its loss does not affect short-term memory.

    #neuroscience #dopamine #LearningAndMemory #Drosophila

  10. @elduvelle @LMPrida @biorxivpreprint @cogneurophys I’m stoked that it worked out so well! The assessment followed closely the methods in Navas-Olive CNN paper elifesciences.org/articles/777 using F1 (balanced accuracy) to reflect both precision and recall (i.e. sensitivity). So both FN and FPs count against the score, equally. The human raters were around .7 and the monkey data started at ~.5 and reached ~.6 (same as mouse levels!) after retraining. A pleasant surprise, given visible differences in the SWR phenotype between rodent and primate clades!

    I think Andrea will post more details soon, but meanwhile, some relevant keywords for interested folks (can you think of others we should use?)

    #neuroscience #MemoryReplay #learningandmemory #hippocampus #ripples #SWR #replay #cnn #lstm #openscience #hackathon #oscillations

  11. "Individual dopaminergic neurons induce unique, yet overlapping combinations of behavioural modulations including safety learning, memory retrieval and acute locomotion" by Toshima et al. (Michael Schleyer) 2025
    biorxiv.org/content/10.1101/20

    #neuroscience #Drosophila #dopamine #LearningAndMemory

  12. @brembs @eLife

    Indeed, the field has modernly narrowed the scope of research in associative learning to just the mushroom body.

    We'd have to convince Yoshi Aso, Glen Turner and Gerry Rubin, regarding the title edit. Have you written to them about this? Particularly Yoshi.

    #Drosophila #LearningAndMemory

  13. Excessive olfactory memory in the insomniac fruit fly mutant:

    "we report our surprising findings that insomniac (inc) Drosophila short sleep mutants, which lack a crucial adaptor protein for the autism-associated Cullin-3 ubiquitin ligase, exhibited excessive olfactory memory."

    And then the paper goes on to inquire into the molecular basis of this, and reports:

    "find that a mild attenuation of Protein Kinase A (PKA) signaling specifically rescued the sleep and longevity phenotypes of inc mutants. Surprisingly, this mild PKA signaling reduction further boosted the excessive memory in inc mutants, coupled with further exaggerated mushroom body overgrowth phenotypes."

    From:
    "Cognitive hyperplasticity drives insomnia", by Huang et al. (Sigrist lab) 2024
    biorxiv.org/content/10.1101/20

    #Drosophila #neuroscience #LearningAndMemory

  14. Latest from Gaia Tavosanis' lab: "How does the fly mushroom body support odour categorisation and discrimination? 🧠✨ Dive into Ivy Chan's findings on how neural circuits enable complex olfactory processing in flies."

    "Odour representations supporting ethology-relevant categorisation and discrimination in the Drosophila mushroom body", Chan et al. 2025 (Tavosanis' lab)
    biorxiv.org/content/10.1101/20
    #Drosopila #neuroscience #LearningAndMemory

  15. @futurebird One key difference in the moth vs. the fruit fly:

    "larvae trained at third instar still showed odor aversion after two molts, as fifth instars, but did not avoid the odor as adults, consistent with the idea that post-metamorphic recall involves regions of the brain that are not produced until later in larval development."

    journals.plos.org/plosone/arti

    ... whereas fly larvae don't develop further brain regions during larval life.

    #moths #LearningAndMemory #neuroscience #development #Drosophila

  16. "Selective consolidation of learning and memory via recall-gated plasticity", Lindsey and Litwin-Kumar, 2024.
    elifesciences.org/reviewed-pre

    On forming long-term memories:

    "The key component of this model is a mechanism by which a long-term learning and memory system prioritizes the storage of synaptic changes that are consistent with prior updates to the short-term system. This mechanism, which we refer to as recall-gated consolidation, has the effect of shielding long-term memory from spurious synaptic changes, enabling it to focus on reliable signals in the environment."

    With a discussion including mammalian and insect brains.

    #neuroscience #LearningAndMemory #RecallGatedConsolidation #CompNeurosci

  17. "Beyond prediction error: 25 years of modeling the associations formed in the insect mushroom body", a review by Barbara Webb 2024.

    learnmem.cshlp.org/content/31/

    #Drosophila #neuroscience #LearningAndMemory

  18. @eLife

    "Tyramine and its Amtyr1 receptor modulate attention in honey bees (Apis mellifera)", Latshaw et al. 2013 (Brian Smith's lab).
    elifesciences.org/articles/833

    Genetics and crosses in honeybees: the patience to do these experiments is admirable. Plus electrophysiology!

    #honeybees #neuroscience #LearningAndMemory #LatentInhibition

  19. Prof. Karla Kaun and her lab review "Drosophila Reward Circuits" oxfordre.com/neuroscience/disp

    Reviews both the adult and larval Drosophila brain circuits for feeding, sugar sensing, and associative memory, including the roles of neuromodulators and neuropeptides.

    #neuroscience #Drosophila #dopamine #LearningAndMemory

  20. @DrYohanJohn

    Let’s bring back into the limelight Jurgen Schmidhuber’s ~2009 take on compression as the root of a lot that goes on in learning and its impact/causality on beauty, novelty, boringness/interestingness, and action selection.

    “Driven by compression progress: A simple principle explains essential aspects of subjective beauty, novelty, surprise, interestingness, attention, curiosity, creativity, art, science, music, jokes” by Schmidhuber 2008. arxiv.org/pdf/0812.4360

    #neuroscience #LearningAndMemory #NeuralNetworks

  21. "Flexible specificity of memory in Drosophila depends on a comparison between choices", by Modi et al. 2023 (Glenn Turner's lab) elifesciences.org/articles/809

    "A memory too specific will be useless in even a slightly different environment, while an overly general memory may lead to suboptimal choices."

    "Rather than forming memories that strike a balance between specificity and generality, Drosophila can flexibly categorize a given stimulus into different groups depending on the options available."

    #neuroscience #LearningAndMemory #MushroomBody #Drosophila

  22. @scottishwaddell

    Wow Scott—the abstract alone is like a mini neuroscience conference on learning and memory. Looking forward to reading it slowly.

    Meanwhile: could you tell us about the voltage imaging? Any caveats?

    #Drosophila #neuroscience #LearningAndMemory #MushroomBody #KenyonCells #engran #MultisensoryIntegration

  23. Upcoming learning & memory conference: the mushroom body meeting 2023 has been announced!

    When: 30th May – 1st June
    Where: Göttingen, Germany
    Register at: mushroom-body-meeting.org/regi

    Organized by André Fiala, Ilona Grunwald Kadow and Yoshi Aso.

    Speaker list: mushroom-body-meeting.org/spea

    #neuroscience #Drosophila #learningAndMemory #learning

  24. Going to #SfN22 ?

    Come in for a chat on all things sex differences in memory, feeding, and anxiety:
    
📚 Sunday Nov 13 8-9am #157.05
“Hippocampal interleukin-6
affects mnemonic functions
and emotionality in a sex-dependent manner”
    
🍽️ Monday Nov 14 4-5pm #400.17
“From an empty stomach to anxiolysis: molecular and
behavioral sex differences in
ghrelin axis”
    
See you soon!
    #SfN2022 #Neuroscience2022#IngestiveBehavior #Neuroscience #LearningAndMemory #PhD

  25. #introduction

    Hi everyone!

    I am an Assistant Professor in the Dept. of Biology at #HopeCollege (#PUI). I study #Behavior and #Neuroimmunology in mice and humans. My research uses #drugs of abuse (i.e. #morphine and #alcohol) and #space radiation to probe how peripheral #immune responses impact #cognition . I #teach and #mentor #undergraduates (#STEM) how to think about #science and challenge them to question HOW they know content. Here are some other topics/tags that I am fond of: #drugsofabuse #spaceradiation #learningandmemory #adultneurogenesis #microglia #macrophage #mentalhealth