#cerebralcortex — Public Fediverse posts

"Short-term memory errors are strongly associated with a drift in neural activity in the posterior parietal cortex", Joon Ho Choi et al. 2025 (Jong-Cheol Rah's lab).

"Using 2-photon calcium imaging in the posterior parietal cortex (PPC) of mice performing a delayed match-to-sample task, we identified a subset of PPC neurons exhibiting both directional and temporal selectivity. Contrary to the hypothesis that STM errors primarily stem from mis-encoding during the sample phase, our findings reveal that these errors are more strongly associated with a drift in neural activity during the delay period. This drift leads to a gradual divergence away from the correct representation, ultimately leading to incorrect behavioral responses."

#neuroscience #LearningAndMemory #CerebralCortex #STM

Conflicting results have been obtained re changes in synaptic strength in the #CerebralCortex during the #Sleep-WakeCycle. This computational study provides a comprehensive understanding & unified framework about #synaptic dynamics during #sleep & wake states @PLOSBiology https://plos.io/4kHeNwM

#WarrenBrown - What Is #Consciousness?

https://www.youtube.com/watch?v=THaRnugEU3s

#Philosophy #PhilosophyOfScience #Science #PhilosophyOfConsciousness #SelfConsciousness #PhilosophyOfMind #Mind #Emergence #Brain #Cortex #CerebralCortex #Memory #Neuroscience #Neurophysiology #Action #IntentionalStates #Intentionality #NervousSystem #Phenomenology #Qualia #Experience #CloserToTruth #RobertKuhn

“we identified a sparse subset of neurons in the primary visual cortex (V1) and higher visual areas that respond emergently to ICs [illusory contours]. We found that these highly selective "IC-encoders" mediate the neural representation of IC inference. Strikingly, selective activation of these neurons using two-photon holographic optogenetics was sufficient to recreate IC representation in the rest of the V1 network, in the absence of any visual stimulus.”

From: “Recurrent pattern completion drives the neocortical representation of sensory inference” by Shin et al. 2023 https://www.biorxiv.org/content/10.1101/2023.06.05.543698v1

#neuroscience #NeuroPixels #mouse #CerebralCortex

@J_Exp_Biol

Switchable neural components in turtles. Perhaps not surprising but certainly extraordinary! The source paper:

"Responses of the in vitro turtle brain to visual and auditory stimuli during severe hypoxia", Ariel et al. 2023 https://doi.org/10.1242/jeb.244687

"North American pond turtles (Emydidae) are renowned for their ability to survive extreme hypoxia and anoxia, which enables several species to overwinter in ice-locked, anoxic freshwater ponds and bogs for months."

These qualities make turtles fantastic laboratory animals for neuroscience research:

"Large-scale mapping of cortical synaptic projections with extracellular electrode arrays", Shein-Idelson et al. 2017 https://www.nature.com/articles/nmeth.4393

#neuroscience #reptiles #Testudines #turtles #vision #CerebralCortex #hibernation