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43 results for “senescence”
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📃New paper in Ecology letters 🐦 by Bertille Mohring et al.
Life-history trade-offs and #senescence in black-browed #albatrosses from Kerguelen and Bird Island
Black-browed #albatrosses breeding in more variable environments display slower life histories (slow, late-onset reproductive senescence) and greater among-individual variation in life-history strategies
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Cellular #senescence is a biological paradigm in which a unique subpopulation of cells permanently and irreversibly stops dividing but evades apoptosis (programmed cell death). Instead of dying off, these arrested "zombie cells" remain metabolically hyperactive and linger within mammalian tissues.
#WhatIs #MolecularBiology #CellBiology #Geroscience #Longevity #sflorg
https://www.sflorg.com/2026/03/wi03202601.html -
Cellular Senescence in Health, Disease and Aging: Blessing or Curse? by Markus Riessland, 2021
When Hayflick and Moorhead coined the term “cellular senescence” (CS) almost 60 years ago, this phenomenon was understood as a mechanism, usually induced by activation of the DNA-repair machinery, to prevent uncontrolled proliferation.
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Cellular Senescence and Brain Aging: Mechanisms, Therapeutic Strategies, and Implications for Neurodegenerative Diseases by Gaurav Gupta, 2025
In Cellular Senescence and Brain Aging, leading scientists and experts examine
how brain aging relates to senescent cells in the body. This book combines cellular biology and neuroscience, combining molecular, experimental, and translational information.https://link.springer.com/book/10.1007/978-981-96-8873-9
@bookstodon
#books
#brain
#ageing
#senescence
#neurodegeneration -
#KnowledgeByte: Negligible #Senescence is a term that describes organisms that don't show signs of biological aging, such as reduced reproductive capability, functional decline, or increased death rates with age.
It can also be described as a similar term to biological #Immortality, which means that an organism isn't more likely to die as it gets older.
https://knowledgezone.co.in/posts/Animals-that-Defy-Aging-664c3b7f9c4ce129fae5d57c
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GenX is going to countenance its senescence with the same attitude we did our youth. I was just listening to Sirius XM Lithium (90s alt grunge) and heard the station id which included:
“Some of these songs are older than your interns. Deal with it!”
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GenX is going to countenance its senescence with the same attitude we did our youth. I was just listening to Sirius XM Lithium (90s alt grunge) and heard the station id which included:
“Some of these songs are older than your interns. Deal with it!”
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GenX is going to countenance its senescence with the same attitude we did our youth. I was just listening to Sirius XM Lithium (90s alt grunge) and heard the station id which included:
“Some of these songs are older than your interns. Deal with it!”
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GenX is going to countenance its senescence with the same attitude we did our youth. I was just listening to Sirius XM Lithium (90s alt grunge) and heard the station id which included:
“Some of these songs are older than your interns. Deal with it!”
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GenX is going to countenance its senescence with the same attitude we did our youth. I was just listening to Sirius XM Lithium (90s alt grunge) and heard the station id which included:
“Some of these songs are older than your interns. Deal with it!”
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📰 "Small extracellular vesicles reflect senescence progression in human bone marrow-derived mesenchymal stem cells during hollow fiber bioreactor culture"
https://doi.org/doi:10.7150/ntno.132088
https://pubmed.ncbi.nlm.nih.gov/42694646/
#Extracellular #Mechanical -
📰 "Small extracellular vesicles reflect senescence progression in human bone marrow-derived mesenchymal stem cells during hollow fiber bioreactor culture"
https://doi.org/doi:10.7150/ntno.132088
https://pubmed.ncbi.nlm.nih.gov/42694646/
#Extracellular #Mechanical -
New visualization: Molecular Signatures Distinguish Distinct Senescence Programs
#CellularSenescence #SASP #Senescence #CellBiology #DataVizualization #MolecularBiology #Aging #Oncology
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Postdoctoral Fellow Position in Cell Stress/Senescence
UNIVERSITY OF WISCONSIN-MADISON
Come join us as postdoc in #senescence and #stress in diabetes
See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95778
#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95778 -
Postdoctoral Fellow Position in Cell Stress/Senescence
UNIVERSITY OF WISCONSIN-MADISON
Come join us as postdoc in #senescence and #stress in diabetes
See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95378
#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95378 -
Postdoctoral Fellow Position in Cell Stress/Senescence
UNIVERSITY OF WISCONSIN-MADISON
Come join us as postdoc in #senescence and #stress in diabetes
See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95011
#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=95011 -
Postdoctoral Fellow Position in Cell Stress/Senescence
UNIVERSITY OF WISCONSIN-MADISON
Come join us as postdoc in #senescence and #stress in diabetes
See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=94419
#autoimmune_diseases #beta_cell #cell...
https://jobrxiv.org/job/university-of-wisconsin-madison-27778-postdoctoral-fellow-position-in-cell-stress-senescence/?feed_id=94419 -
Marcescence
…still holding on 😊
Not senescence in this case 🤔#GetOutside #Hiking #Nature #Walking #Creek #Marcescence #Senescence #Aging #Meditation #Photography
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my reading for this evening -
Aging: a possible road toward gut microbiota pathoadaptation [2025]
https://pubmed.ncbi.nlm.nih.gov/40770832/ -
Scientists Have Discovered a Special Type of Immune Cell That Slows Aging
Researchers have just discovered a way to destroy harmful 'senescent' cells that accumulate with age and ramp up the kind of tissue damage and inflammation that slowly brings life to a grinding halt.
The team found that CD4 T immune cells transform into assassins of the damaging tissues when biological aging is detected in the body.
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https://www.europesays.com/ie/343946/ Polyploidy-induced senescence may influence aging and cancer risk #Aging #Bladder #cancer #Carcinogenesis #Carcinomas #Cell #CellCycle #DNA #DNADamage #Éire #Genetic #Health #IE #Ireland #Research #Stress #therapy #Tumor #Tumorigenesis
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“The Trump administration’s new rule requiring states to submit voter data to a federal portal before national mail-in ballots can be sent is now in effect, USPS announced. The service acknowledged pending litigation against the rule, including from nearly two dozen Democratic-led states.”
https://mailchi.mp/notus/ace-of-trades-10348220?e=8a121a40cc
#USpol #MentalHealth #Senescence (1/2)
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Disposable soma theory of aging (Evolution 🧬)
In biogerontology, the disposable soma theory of aging states that organisms age due to an evolutionary trade-off between growth, reproduction, and DNA repair maintenance. Formulated by British biologist Thomas Kirkwood, the disposable soma theory explains that an organism only has a limited amount of...
https://en.wikipedia.org/wiki/Disposable_soma_theory_of_aging
#DisposableSomaTheoryOfAging #Evolution #Senescence #FreeRadicals #TheoriesOfAgeing
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Another excellent essay from Shanaka Anslem Perera. No idea where he finds the time to be this prolific, at this depth, but I'm very glad that he does.
A theory on failure modes of longevity drug promises, and an argument for concentrating on living well rather than on living longer.
https://shanakaanslemperera.substack.com/p/the-counterfeit-clock
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https://medicalxpress.com/news/2025-09-rapamycin-linked-dna-resilience-aging.html
(boomer bolstering )
Originally developed for organ transplantation to prevent immune rejection, previous research has found that, at non-#immunosuppressive doses, #rapamycin can mitigate cellular #senescence.
"rapamycin provides direct #genomicprotection in human immune cells and may support healthy aging, offer benefits after clinical #radiationexposure, and could even address risks from #cosmicradiation during extended #spacetravel."
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Mutation accumulation theory (Evolutionary biology 🧬)
The mutation accumulation theory of aging was first proposed by Peter Medawar in 1952 as an evolutionary explanation for biological aging and the associated decline in fitness that accompanies it. Medawar used the term 'senescence' to refer to this process. The theory explains that, in the case where harmful ...
https://en.wikipedia.org/wiki/Mutation_accumulation_theory
#MutationAccumulationTheory #Genetics #Senescence #EvolutionaryBiology
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A new transparent #killifish line called klara, generated using #CRISPR/Cas9, can significantly simplify explorations of #development, #senescence, ageing and #regeneration. #ModelOrganism https://elifesciences.org/articles/81549?utm_source=mastodon&utm_medium=social&utm_campaign=organic
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Age is no better, hardly so well, qualified for an instructor as youth, for it has not profited so much as it has lost.
Henry David Thoreau (1817-1862) American philosopher and writer
Walden; or, Life in the Woods, ch. 1 “Economy” (1854)More about this quote: wist.info/thoreau-henry-david/…
#quote #quotes #quotation #qotd #thoreau #henrydavidthoreau #walden #age #decline #elder #instruction #oldage #senescence #teaching #wisdom #youth
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Researchers have identified a novel cluster of liver cells (hepatocytes) that specifically emerge during metabolic dysfunction-associated steatohepatitis (MASH). These cells exhibit unique gene expression and cellular senescence, acting as a critical regulator of liver disease progression.
#Hepatology #CellBiology #DevelopmentalBiology #MolecularGenetics #sflorg
https://www.sflorg.com/2026/05/bio05042601.html
