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#trpchannels — Public Fediverse posts

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  1. CW: Erythromelalgia, pain, SCN9A / Nav1.7

    I should probably mention that like the woman in 1st case report, I also have MCAS symptoms, as well as other pain and paresthesia in my hands and elsewhere. I had a colonoscopy a few months after this started and for the prep I ate mostly just white rice and tapioca - no fruit or veg. I felt much, much better on the colonoscopy prep diet. Since then my diet has become quite restricted as I noticed more pain when I ate cruciferous veg, alliums, legumes - lots of stuff.

    So it is possible some of my erythromelalgia symptom improvement is due to having a limited diet - which is probably not so great for long term health overall.

    I have wondered if there is TRP channel involvement since isothiocyanates and other food components can activate TRP channels, as can heat exposure.

    Then there is the possibility of a connection to mast cells to consider.

    #TRPchannels #MCAS #erythromelalgia