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#singlemolecule — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #singlemolecule, aggregated by home.social.

  1. Our preprint is up! Take a look if you like kinesin, microtubule transport, single molecule FRET or biophysics. It’s a bit of shift to how we’ve been used to thinking about kinesin-1 regulation as we try to get a handle on its conformational dynamics. Super proud of to have this milestone out in the world and all the hard work it represents from everyone involved.
    #kinesin #microtubules #biophys #smFRET #SingleMolecule #AxonalTransport biologists.social/@Twelvetrees

  2. Does anyone have strong opinions on what the best/most sensitive low volume spectrophotometer is? Looking to quantify low concentrations of fluorescently labelled protein, not just DNA etc

    #biochem #biophys #singlemolecule

  3. Our work has made the inside cover! Check out "#singlemolecule #electrochemical imaging resolves the midpoint potentials of individual fluorophores on nanoporous antimony-doped tin oxide" in the latest issue of @chemicalscience! doi.org/10.1039/d3sc05293a @washuengineers #WashUESE #WUSTL

  4. Our work has made the inside cover! Check out "#singlemolecule #electrochemical imaging resolves the midpoint potentials of individual fluorophores on nanoporous antimony-doped tin oxide" in the latest issue of @chemicalscience! doi.org/10.1039/d3sc05293a @washuengineers #WashUESE #WUSTL

  5. Our work has made the inside cover! Check out "#singlemolecule #electrochemical imaging resolves the midpoint potentials of individual fluorophores on nanoporous antimony-doped tin oxide" in the latest issue of @chemicalscience! doi.org/10.1039/d3sc05293a @washuengineers #WashUESE #WUSTL

  6. Our work has made the inside cover! Check out "#singlemolecule #electrochemical imaging resolves the midpoint potentials of individual fluorophores on nanoporous antimony-doped tin oxide" in the latest issue of @chemicalscience! doi.org/10.1039/d3sc05293a @washuengineers #WashUESE #WUSTL

  7. Our work has made the inside cover! Check out "#singlemolecule #electrochemical imaging resolves the midpoint potentials of individual fluorophores on nanoporous antimony-doped tin oxide" in the latest issue of @chemicalscience! doi.org/10.1039/d3sc05293a @washuengineers #WashUESE #WUSTL

  8. Congratulations to Prof. Jin Lu, now at the National Center for Nanoscience, whose work on #singlemolecule #electrochemical imaging is now online in Chemical Science. Happy New Year!
    #SMLM #WashU #WUSTL @chemicalscience #ChemicalScience

    "Single-Molecule Electrochemical Imaging Resolves the Midpoint Potentials of Individual Fluorophores on Nanoporous Antimony-Doped Tin Oxide"
    Chemical Science, 2024
    doi.org/10.1039/D3SC05293A

  9. Congratulations to Prof. Jin Lu, now at the National Center for Nanoscience, whose work on #singlemolecule #electrochemical imaging is now online in Chemical Science. Happy New Year!
    #SMLM #WashU #WUSTL @chemicalscience #ChemicalScience

    "Single-Molecule Electrochemical Imaging Resolves the Midpoint Potentials of Individual Fluorophores on Nanoporous Antimony-Doped Tin Oxide"
    Chemical Science, 2024
    doi.org/10.1039/D3SC05293A

  10. Congratulations to Prof. Jin Lu, now at the National Center for Nanoscience, whose work on #singlemolecule #electrochemical imaging is now online in Chemical Science. Happy New Year!
    #SMLM #WashU #WUSTL @chemicalscience #ChemicalScience

    "Single-Molecule Electrochemical Imaging Resolves the Midpoint Potentials of Individual Fluorophores on Nanoporous Antimony-Doped Tin Oxide"
    Chemical Science, 2024
    doi.org/10.1039/D3SC05293A

  11. Congratulations to Prof. Jin Lu, now at the National Center for Nanoscience, whose work on #singlemolecule #electrochemical imaging is now online in Chemical Science. Happy New Year!
    #SMLM #WashU #WUSTL @chemicalscience #ChemicalScience

    "Single-Molecule Electrochemical Imaging Resolves the Midpoint Potentials of Individual Fluorophores on Nanoporous Antimony-Doped Tin Oxide"
    Chemical Science, 2024
    doi.org/10.1039/D3SC05293A

  12. new citation:

    `Using salt tolerance compartmentalized self-replication (stCSR) and a #microfluidic platform, we obtained 11 mutant sites with enhanced salt tolerance attributes. #Sequencing and #biochemical analyses revealed that the substitution of conserved amino acids such as G197D, Y369E, T372N, and I378R plays a critical role in maintaining the #processivity of exonuclease-deficient #phi29 #polymerase under high salt conditions.`

    frontiersin.org/articles/10.33

    #nanopore #DNA #singleMolecule

  13. new citation:

    `Using salt tolerance compartmentalized self-replication (stCSR) and a #microfluidic platform, we obtained 11 mutant sites with enhanced salt tolerance attributes. #Sequencing and #biochemical analyses revealed that the substitution of conserved amino acids such as G197D, Y369E, T372N, and I378R plays a critical role in maintaining the #processivity of exonuclease-deficient #phi29 #polymerase under high salt conditions.`

    frontiersin.org/articles/10.33

    #nanopore #DNA #singleMolecule

  14. new citation:

    `Using salt tolerance compartmentalized self-replication (stCSR) and a #microfluidic platform, we obtained 11 mutant sites with enhanced salt tolerance attributes. #Sequencing and #biochemical analyses revealed that the substitution of conserved amino acids such as G197D, Y369E, T372N, and I378R plays a critical role in maintaining the #processivity of exonuclease-deficient #phi29 #polymerase under high salt conditions.`

    frontiersin.org/articles/10.33

    #nanopore #DNA #singleMolecule

  15. new citation:

    `Using salt tolerance compartmentalized self-replication (stCSR) and a #microfluidic platform, we obtained 11 mutant sites with enhanced salt tolerance attributes. #Sequencing and #biochemical analyses revealed that the substitution of conserved amino acids such as G197D, Y369E, T372N, and I378R plays a critical role in maintaining the #processivity of exonuclease-deficient #phi29 #polymerase under high salt conditions.`

    frontiersin.org/articles/10.33

    #nanopore #DNA #singleMolecule

  16. new citation:

    `Using salt tolerance compartmentalized self-replication (stCSR) and a #microfluidic platform, we obtained 11 mutant sites with enhanced salt tolerance attributes. #Sequencing and #biochemical analyses revealed that the substitution of conserved amino acids such as G197D, Y369E, T372N, and I378R plays a critical role in maintaining the #processivity of exonuclease-deficient #phi29 #polymerase under high salt conditions.`

    frontiersin.org/articles/10.33

    #nanopore #DNA #singleMolecule

  17. Iva Lučić shows our students how to label CaMKII with fluorescent dye for #singleMolecule TIRF #microscopy #biophysics

  18. Hello! A new intro for a new instance.

    I lead a research group trying to figure out axonal transport and neurodegeneration. A big emphasis on the microtubules and their motors, but really the transport of anything that doesn't have a membrane around it. For this we use a lot of single molecule methods and live cell imaging. I also post about research culture.

    #introduction #kinesin #dynein #microtubules #neurodegeneration #AxonalTransport #neurobiology #SingleMolecule #CellBiology

  19. "By controlling the distance between the #nanopore and glass surface, we can actively select the region of interest on the molecule and scan it a controlled number of times and at a controlled velocity. Decreasing the velocity and averaging thousands of consecutive readings of the same molecule increases the signal-to-noise ratio by two orders of magnitude compared with free translocations."

    nature.com/articles/s41565-023

    #DNA #singleMolecule #biosensor

  20. 🧐 #MeetTheSpeaker!

    🔬 What are the next advancements in the field of #singlemolecule sequencing technologies? We talked about it with Francesco Nicassio (Istituto Italiano di Tecnologia)

    “Only together we can really find new solutions”

    #science #sciencemastodon #lifesciences #humantechnopole youtube.com/watch?v=JihuHbYmdY

  21. Super-cool work from our clever colleagues at Cambridge -- whole-cell #3D #singlemolecule #lightfield imaging! #SMLM

    @samofmidworld

    High-density volumetric super-resolution microscopy
    bioRxiv 2023.05.02.539032;
    doi: doi.org/10.1101/2023.05.02.539

  22. Super-cool work from our clever colleagues at Cambridge -- whole-cell #3D #singlemolecule #lightfield imaging! #SMLM

    @samofmidworld

    High-density volumetric super-resolution microscopy
    bioRxiv 2023.05.02.539032;
    doi: doi.org/10.1101/2023.05.02.539

  23. Super-cool work from our clever colleagues at Cambridge -- whole-cell #3D #singlemolecule #lightfield imaging! #SMLM

    @samofmidworld

    High-density volumetric super-resolution microscopy
    bioRxiv 2023.05.02.539032;
    doi: doi.org/10.1101/2023.05.02.539

  24. Super-cool work from our clever colleagues at Cambridge -- whole-cell #3D #singlemolecule #lightfield imaging! #SMLM

    @samofmidworld

    High-density volumetric super-resolution microscopy
    bioRxiv 2023.05.02.539032;
    doi: doi.org/10.1101/2023.05.02.539

  25. 🧐 #MeetTheSpeaker!

    🔬 How can single molecule sequencing technologies change research on the human genome? Listen to Davide Bolognini, Senior Bioinformatician in our Genomics Research Centre.

    “International collaborations, of course, are an essential part for developing new methods”

    #lifesciences #humantechnopole #genomics #singlemolecule #sequencing #humangenome #science #sciencemastodon

    youtu.be/Ka85RhFkPOU