home.social

#gbh — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #gbh, aggregated by home.social.

  1. Just love those speed detectors telling me I’m speeding when I’m on a BIKE

    GBH Thursday

    #GBH #cycling #bike #BikeTooter #boston

  2. Released 44 years ago

    "City Baby Attacked by Rats," the debut album by street punk band Charged GBH, featuring the title track of the same name

    Charged GBH – Live in Leeds 1983 – City Baby Attacked by Rats

    #streetpunk #punkrock #chargedgbh #gbh #punkrockhistory

  3. Death of a patient with mental illness at Shattuck Hospital raises allegations of ‘neglect’

    by Jenifer B. McKim, May 08, 2023, Updated August 07, 2023

    "A 60-year-old Black man committed to #LemuelShattuck Hospital’s #psychiatric ward died a 'painful, untimely death' due in part to the state’s failure to provide adequate health care, according to a report released Monday.

    "#HaywoodEarl, residing at the public hospital in Jamaica Plain, likely would have survived his bout with skin cancer if he’d received a timely diagnosis and appropriate medical treatment, the nonprofit Disability Law Center concluded in a 28-page report."

    [...]

    "Earl’s case is coming to light nearly two months after an investigation by the #GBH News Center for Investigative Reporting revealed a history of problems at the hospital, documented by patients, prisoners and former employees."

    Read more:
    wgbh.org/news/local/2023-05-08

    #LemuelShattuck #BIPOC #PatientAbuse #PatientNeglect #PatternOfAbuse #Psychiatry #Massachusetts #MassDMH
    #HumanRightsAbuses

  4. Death of a patient with mental illness at Shattuck Hospital raises allegations of ‘neglect’

    by Jenifer B. McKim, May 08, 2023, Updated August 07, 2023

    "A 60-year-old Black man committed to #LemuelShattuck Hospital’s #psychiatric ward died a 'painful, untimely death' due in part to the state’s failure to provide adequate health care, according to a report released Monday.

    "#HaywoodEarl, residing at the public hospital in Jamaica Plain, likely would have survived his bout with skin cancer if he’d received a timely diagnosis and appropriate medical treatment, the nonprofit Disability Law Center concluded in a 28-page report."

    [...]

    "Earl’s case is coming to light nearly two months after an investigation by the #GBH News Center for Investigative Reporting revealed a history of problems at the hospital, documented by patients, prisoners and former employees."

    Read more:
    wgbh.org/news/local/2023-05-08

    #LemuelShattuck #BIPOC #PatientAbuse #PatientNeglect #PatternOfAbuse #Psychiatry #Massachusetts #MassDMH
    #HumanRightsAbuses

  5. Death of a patient with mental illness at Shattuck Hospital raises allegations of ‘neglect’

    by Jenifer B. McKim, May 08, 2023, Updated August 07, 2023

    "A 60-year-old Black man committed to #LemuelShattuck Hospital’s #psychiatric ward died a 'painful, untimely death' due in part to the state’s failure to provide adequate health care, according to a report released Monday.

    "#HaywoodEarl, residing at the public hospital in Jamaica Plain, likely would have survived his bout with skin cancer if he’d received a timely diagnosis and appropriate medical treatment, the nonprofit Disability Law Center concluded in a 28-page report."

    [...]

    "Earl’s case is coming to light nearly two months after an investigation by the #GBH News Center for Investigative Reporting revealed a history of problems at the hospital, documented by patients, prisoners and former employees."

    Read more:
    wgbh.org/news/local/2023-05-08

    #LemuelShattuck #BIPOC #PatientAbuse #PatientNeglect #PatternOfAbuse #Psychiatry #Massachusetts #MassDMH
    #HumanRightsAbuses

  6. Death of a patient with mental illness at Shattuck Hospital raises allegations of ‘neglect’

    by Jenifer B. McKim, May 08, 2023, Updated August 07, 2023

    "A 60-year-old Black man committed to #LemuelShattuck Hospital’s #psychiatric ward died a 'painful, untimely death' due in part to the state’s failure to provide adequate health care, according to a report released Monday.

    "#HaywoodEarl, residing at the public hospital in Jamaica Plain, likely would have survived his bout with skin cancer if he’d received a timely diagnosis and appropriate medical treatment, the nonprofit Disability Law Center concluded in a 28-page report."

    [...]

    "Earl’s case is coming to light nearly two months after an investigation by the #GBH News Center for Investigative Reporting revealed a history of problems at the hospital, documented by patients, prisoners and former employees."

    Read more:
    wgbh.org/news/local/2023-05-08

    #LemuelShattuck #BIPOC #PatientAbuse #PatientNeglect #PatternOfAbuse #Psychiatry #Massachusetts #MassDMH
    #HumanRightsAbuses

  7. Death of a patient with mental illness at Shattuck Hospital raises allegations of ‘neglect’

    by Jenifer B. McKim, May 08, 2023, Updated August 07, 2023

    "A 60-year-old Black man committed to #LemuelShattuck Hospital’s #psychiatric ward died a 'painful, untimely death' due in part to the state’s failure to provide adequate health care, according to a report released Monday.

    "#HaywoodEarl, residing at the public hospital in Jamaica Plain, likely would have survived his bout with skin cancer if he’d received a timely diagnosis and appropriate medical treatment, the nonprofit Disability Law Center concluded in a 28-page report."

    [...]

    "Earl’s case is coming to light nearly two months after an investigation by the #GBH News Center for Investigative Reporting revealed a history of problems at the hospital, documented by patients, prisoners and former employees."

    Read more:
    wgbh.org/news/local/2023-05-08

    #LemuelShattuck #BIPOC #PatientAbuse #PatientNeglect #PatternOfAbuse #Psychiatry #Massachusetts #MassDMH
    #HumanRightsAbuses

  8. Teen charged with GBH after Milford Haven school stabbing as police confirm injuries were stab wounds

    Detectives say the teenager has been charged with Section 18 Grievous Bodily Harm and possession of a bladed article on school premises. He has been remanded in custody and is due to appear before Swansea Magistrates Court today.

    It comes after officers revealed that injuries initially described as “non‑stab injuries” have now been confirmed as stab wounds following detailed medical assessment.

    ‘Victim being supported after traumatic event’

    Senior Investigating Officer DCI Matthew Briggs said the early description of the injuries was based on “preliminary information” available at the time, but specialist enquiries have since confirmed the wounds were caused by a blade.

    He said the victim — understood to be a member of staff — is continuing to receive support as they recover from what police described as a “traumatic event”.

    The school went into lockdown on Thursday after the incident, with pupils kept in classrooms while officers secured the site. Staff were praised for their calm and professional response.

    Increased police presence to continue

    Police say there will be a higher‑than‑usual presence around the school and surrounding area over the coming days to reassure pupils, parents and staff.

    Officers will also be working with local secondary schools next week to offer support and guidance.

    The school is expected to reopen as planned on Monday, with the headteacher previously telling parents that safety measures and wellbeing support will be in place.

    A community still reeling

    The incident has shocked Milford Haven, with parents describing the lockdown as “terrifying” and pupils reporting a heavy police presence around the site.

    It follows two days of intense speculation online, which police have repeatedly urged the public not to fuel while the investigation continues.

    This latest update confirms the most serious charge available for an assault of this nature, signalling the gravity of the incident and the scale of the ongoing investigation.

    Related stories from Swansea Bay News

    Teacher injured as Milford Haven school goes into lockdown
    The first details after the school was locked down and a teenager was arrested.

    Milford Haven school to reopen on Monday after lockdown incident
    Staff praised for their calm response as the school prepares to welcome pupils back.

    #GBH #GrievousBodilyHarm #knifeCrime #MilfordHaven #MilfordHavenSchool #possessionOfABladedArticle #possessionOfABladedArticleOnSchoolPremises #teacherAssaulted #YsgolGyfunAberdaugleddau
  9. #LiveMusic #Punk #UKPunk

    Had a great time at the fleece in brizzle last night with my daughter. Saw #Conflict #dischargeband #gbh and a first for me, because they had become culture shock by the time I was old enough to go gigging, #Subhumans

    Conflict's new singer is *really* good. Dont know their name.

    Discharge were well on form 🤘

    GBH took a few songs to ease into it but from about 1/2 way into their set they were smashing it.

    Subhumans were amazing. Dick is a pro frontman.

  10. #LiveMusic #Punk #UKPunk

    Had a great time at the fleece in brizzle last night with my daughter. Saw #Conflict #dischargeband #gbh and a first for me, because they had become culture shock by the time I was old enough to go gigging, #Subhumans

    Conflict's new singer is *really* good. Dont know their name.

    Discharge were well on form 🤘

    GBH took a few songs to ease into it but from about 1/2 way into their set they were smashing it.

    Subhumans were amazing. Dick is a pro frontman.

  11. #LiveMusic #Punk #UKPunk

    Had a great time at the fleece in brizzle last night with my daughter. Saw #Conflict #dischargeband #gbh and a first for me, because they had become culture shock by the time I was old enough to go gigging, #Subhumans

    Conflict's new singer is *really* good. Dont know their name.

    Discharge were well on form 🤘

    GBH took a few songs to ease into it but from about 1/2 way into their set they were smashing it.

    Subhumans were amazing. Dick is a pro frontman.

  12. Had a great time at the fleece in brizzle last night with my daughter. Saw and a first for me, because they had become culture shock by the time I was old enough to go gigging,

    Conflict's new singer is *really* good. Dont know their name.

    Discharge were well on form 🤘

    GBH took a few songs to ease into it but from about 1/2 way into their set they were smashing it.

    Subhumans were amazing. Dick is a pro frontman.

  13. The last days of a shitty year, my best friend died of a brain tumour. Irreplaceable! Never again freely discuss God and this mad world. Among other things… We were young, pissed off, and we needed #hardcore #punk! #GBH - #CityBabyAttackedByRats! #music #80s youtu.be/-To8BnOdMDsb

    City Baby Attacked By Rats

  14. Outre-mer : les habitants face à l’emprise du groupe Bernard #Hayot mastodon.social/@la_voix/tagge

    Omniprésent dans les #Outremer le groupe #BernardHayot mastodon.social/@la_voix/11574 est décrié par les militants contre la vie chère, qui l’accusent de profiter de sa situation dominante et d’entretenir une dépendance structurelle. reporterre.net/Tant-qu-il-aura

    #societe #actualite #GBH

  15. Outre-mer : les habitants face à l’emprise du groupe Bernard #Hayot mastodon.social/@la_voix/tagge

    Omniprésent dans les #Outremer le groupe #BernardHayot mastodon.social/@la_voix/11574 est décrié par les militants contre la vie chère, qui l’accusent de profiter de sa situation dominante et d’entretenir une dépendance structurelle. reporterre.net/Tant-qu-il-aura

    #societe #actualite #GBH

  16. Outre-mer : les habitants face à l’emprise du groupe Bernard #Hayot mastodon.social/@la_voix/tagge

    Omniprésent dans les #Outremer le groupe #BernardHayot mastodon.social/@la_voix/11574 est décrié par les militants contre la vie chère, qui l’accusent de profiter de sa situation dominante et d’entretenir une dépendance structurelle. reporterre.net/Tant-qu-il-aura

    #societe #actualite #GBH

  17. Outre-mer : les habitants face à l’emprise du groupe Bernard #Hayot mastodon.social/@la_voix/tagge

    Omniprésent dans les #Outremer le groupe #BernardHayot mastodon.social/@la_voix/11574 est décrié par les militants contre la vie chère, qui l’accusent de profiter de sa situation dominante et d’entretenir une dépendance structurelle. reporterre.net/Tant-qu-il-aura

    #societe #actualite #GBH

  18. Une information judiciaire a été ouverte pour " #escroquerie " contre le groupe #BernardHayot mastodon.social/@la_voix/tagge

    Le parquet national financier a ouvert une information judiciaire pour "escroquerie en bande organisée", "abus de position dominante" et "entente" contre le groupe Bernard #Hayot principal groupe de distribution d'outre-mer la1ere.franceinfo.fr/une-infor

    #GBH #justice #corruption

  19. Une information judiciaire a été ouverte pour " #escroquerie " contre le groupe #BernardHayot mastodon.social/@la_voix/tagge

    Le parquet national financier a ouvert une information judiciaire pour "escroquerie en bande organisée", "abus de position dominante" et "entente" contre le groupe Bernard #Hayot principal groupe de distribution d'outre-mer la1ere.franceinfo.fr/une-infor

    #GBH #justice #corruption

  20. Une information judiciaire a été ouverte pour " #escroquerie " contre le groupe #BernardHayot mastodon.social/@la_voix/tagge

    Le parquet national financier a ouvert une information judiciaire pour "escroquerie en bande organisée", "abus de position dominante" et "entente" contre le groupe Bernard #Hayot principal groupe de distribution d'outre-mer la1ere.franceinfo.fr/une-infor

    #GBH #justice #corruption

  21. Une information judiciaire a été ouverte pour " #escroquerie " contre le groupe #BernardHayot mastodon.social/@la_voix/tagge

    Le parquet national financier a ouvert une information judiciaire pour "escroquerie en bande organisée", "abus de position dominante" et "entente" contre le groupe Bernard #Hayot principal groupe de distribution d'outre-mer la1ere.franceinfo.fr/une-infor

    #GBH #justice #corruption

  22. Environmental #pesticide exposure and the risk of irritable bowel syndrome: A case-control study

    Environmental Toxicology and Pharmacology
    Volume 98, March 2023, 104076
    Lola Rueda-Ruzafa, Pablo Roman, Diana Cardona, Mar Requena, Carmen Ropero-Padilla, Raquel Alarcón

    Highlights

    • The risk of irritable bowel syndrome is higher in areas of high pesticide exposure.
    • Agronomic criteria were used to categorize pesticide exposure in the study population.
    • A total of 18,807 cases of irritable bowel syndrome were studied.
    • Environmental pesticide exposure is linked to irritable bowel syndrome.

    Abstract
    The agricultural model in southern #Spain is highly productive, mainly due to the intensive cultivation under plastic. Despite strict pesticide regulation, human exposure to pesticides in the environment has been connected to an increase in diseases such as #CeliacDisease. Certain pesticides have also been associated to the disruption of the intestinal #microbiota, which has been xtied to the development of irritable bowel syndrome (IBS). A case-control study was conducted in Andalusia, south #Spain, to assess the prevalence and risk of IBS related to pesticide exposure. This research found a high prevalence of IBS in #Andalusia between 2000 and 2021 in areas with high pesticide exposure using agronomic criteria. Furthermore, the odds ratio for IBS was significantly higher in the population with high pesticide exposure. This study suggests that pesticides may be involved in IBS, whereas more research is needed to determine the role of pesticides in IBS symptomatology.

    Excerpts: "[In the locations of the study], the most commonly used insecticides are #organophosphates (primarily chlorpyrifos), N-methylcarbamates, macrocyclic lactones, #neonicotinoids, and pyrethroids. #Fungicides frequently used in plastic greenhouses include (di) thiocarbamates, conazoles, dicarboximide), anilino-pyrimidines, and copper salts. Bipyridyl (paraquat, diquat), organophosphonates (#glyphosate), chlorotriazine, and phenylurea are the herbicides most popularly used in the study areas (García-García et al., 2016)."

    [...]

    Studies on Rats

    "A wide range of environmental pollutants, including heavy metals, insecticides, herbicides, and pesticides, can cause gut dysbiosis (Jin et al., 2015, Lin et al., 2020, Reygner et al., 2016). As suggested in our findings, there is also an increased risk of IBS precisely in pesticide-heavy areas and particularly in women. Previous research have found sexually dimorphic metabolic effect after pesticides exposures (Lukowicz et al., 2018). In this regard, #Roundup®, a glyphosate-based herbicide (#GBH) widely used in Andalusian crops, can increase the #Bacteroidetes group while decreasing the #Lactobacillaceae family in fecal samples of female rats (Lozano et al., 2018). Similarly, chronic glyphosate exposure reduces Corynebacterium, Firmicutes, Bacteroidetes, and Lactobacillus in mice following GBH administration (Aitbali et al., 2018). Exposure to fungicides such as imazalil can also alter the composition of the GM after acute and chronic administration. Specifically, in mice, imazalil increases the relative abundance of Firmicutes, Proteobacteria and Actinobacteria while decreasing the abundance of Bacteroidetes (Jin et al., 2016). Insecticides such as chlorpyrifos, diazinon and aldicarb also disrupt the GM of rats and mice (Aitbali et al., 2018, Gao et al., 2019, Gao et al., 2017, Joly et al., 2013). This modification has been associated with increased intestinal permeability and bacterial translocation in the case of chlorpyrifos (Condette et al., 2014). Diazinon inhibits several SCFA-producing genera in the Lachnospiraceae family, which operate as an energy substrate for colonic epithelial cells, altering energy harvesting in the intestinal epithelium (Gao et al., 2017)."

    Read more:
    sciencedirect.com/science/arti

    #IBS #Bayer #ToxicPesticides
    #Monocrops #Monocrap #BigAg
    #BigChem #Poison #RoundUpKills #USPol #WorldPol #Roundup #Glyphosate #Herbicides

  23. Environmental #pesticide exposure and the risk of irritable bowel syndrome: A case-control study

    Environmental Toxicology and Pharmacology
    Volume 98, March 2023, 104076
    Lola Rueda-Ruzafa, Pablo Roman, Diana Cardona, Mar Requena, Carmen Ropero-Padilla, Raquel Alarcón

    Highlights

    • The risk of irritable bowel syndrome is higher in areas of high pesticide exposure.
    • Agronomic criteria were used to categorize pesticide exposure in the study population.
    • A total of 18,807 cases of irritable bowel syndrome were studied.
    • Environmental pesticide exposure is linked to irritable bowel syndrome.

    Abstract
    The agricultural model in southern #Spain is highly productive, mainly due to the intensive cultivation under plastic. Despite strict pesticide regulation, human exposure to pesticides in the environment has been connected to an increase in diseases such as #CeliacDisease. Certain pesticides have also been associated to the disruption of the intestinal #microbiota, which has been xtied to the development of irritable bowel syndrome (IBS). A case-control study was conducted in Andalusia, south #Spain, to assess the prevalence and risk of IBS related to pesticide exposure. This research found a high prevalence of IBS in #Andalusia between 2000 and 2021 in areas with high pesticide exposure using agronomic criteria. Furthermore, the odds ratio for IBS was significantly higher in the population with high pesticide exposure. This study suggests that pesticides may be involved in IBS, whereas more research is needed to determine the role of pesticides in IBS symptomatology.

    Excerpts: "[In the locations of the study], the most commonly used insecticides are #organophosphates (primarily chlorpyrifos), N-methylcarbamates, macrocyclic lactones, #neonicotinoids, and pyrethroids. #Fungicides frequently used in plastic greenhouses include (di) thiocarbamates, conazoles, dicarboximide), anilino-pyrimidines, and copper salts. Bipyridyl (paraquat, diquat), organophosphonates (#glyphosate), chlorotriazine, and phenylurea are the herbicides most popularly used in the study areas (García-García et al., 2016)."

    [...]

    Studies on Rats

    "A wide range of environmental pollutants, including heavy metals, insecticides, herbicides, and pesticides, can cause gut dysbiosis (Jin et al., 2015, Lin et al., 2020, Reygner et al., 2016). As suggested in our findings, there is also an increased risk of IBS precisely in pesticide-heavy areas and particularly in women. Previous research have found sexually dimorphic metabolic effect after pesticides exposures (Lukowicz et al., 2018). In this regard, #Roundup®, a glyphosate-based herbicide (#GBH) widely used in Andalusian crops, can increase the #Bacteroidetes group while decreasing the #Lactobacillaceae family in fecal samples of female rats (Lozano et al., 2018). Similarly, chronic glyphosate exposure reduces Corynebacterium, Firmicutes, Bacteroidetes, and Lactobacillus in mice following GBH administration (Aitbali et al., 2018). Exposure to fungicides such as imazalil can also alter the composition of the GM after acute and chronic administration. Specifically, in mice, imazalil increases the relative abundance of Firmicutes, Proteobacteria and Actinobacteria while decreasing the abundance of Bacteroidetes (Jin et al., 2016). Insecticides such as chlorpyrifos, diazinon and aldicarb also disrupt the GM of rats and mice (Aitbali et al., 2018, Gao et al., 2019, Gao et al., 2017, Joly et al., 2013). This modification has been associated with increased intestinal permeability and bacterial translocation in the case of chlorpyrifos (Condette et al., 2014). Diazinon inhibits several SCFA-producing genera in the Lachnospiraceae family, which operate as an energy substrate for colonic epithelial cells, altering energy harvesting in the intestinal epithelium (Gao et al., 2017)."

    Read more:
    sciencedirect.com/science/arti

    #IBS #Bayer #ToxicPesticides
    #Monocrops #Monocrap #BigAg
    #BigChem #Poison #RoundUpKills #USPol #WorldPol #Roundup #Glyphosate #Herbicides

  24. Environmental #pesticide exposure and the risk of irritable bowel syndrome: A case-control study

    Environmental Toxicology and Pharmacology
    Volume 98, March 2023, 104076
    Lola Rueda-Ruzafa, Pablo Roman, Diana Cardona, Mar Requena, Carmen Ropero-Padilla, Raquel Alarcón

    Highlights

    • The risk of irritable bowel syndrome is higher in areas of high pesticide exposure.
    • Agronomic criteria were used to categorize pesticide exposure in the study population.
    • A total of 18,807 cases of irritable bowel syndrome were studied.
    • Environmental pesticide exposure is linked to irritable bowel syndrome.

    Abstract
    The agricultural model in southern #Spain is highly productive, mainly due to the intensive cultivation under plastic. Despite strict pesticide regulation, human exposure to pesticides in the environment has been connected to an increase in diseases such as #CeliacDisease. Certain pesticides have also been associated to the disruption of the intestinal #microbiota, which has been xtied to the development of irritable bowel syndrome (IBS). A case-control study was conducted in Andalusia, south #Spain, to assess the prevalence and risk of IBS related to pesticide exposure. This research found a high prevalence of IBS in #Andalusia between 2000 and 2021 in areas with high pesticide exposure using agronomic criteria. Furthermore, the odds ratio for IBS was significantly higher in the population with high pesticide exposure. This study suggests that pesticides may be involved in IBS, whereas more research is needed to determine the role of pesticides in IBS symptomatology.

    Excerpts: "[In the locations of the study], the most commonly used insecticides are #organophosphates (primarily chlorpyrifos), N-methylcarbamates, macrocyclic lactones, #neonicotinoids, and pyrethroids. #Fungicides frequently used in plastic greenhouses include (di) thiocarbamates, conazoles, dicarboximide), anilino-pyrimidines, and copper salts. Bipyridyl (paraquat, diquat), organophosphonates (#glyphosate), chlorotriazine, and phenylurea are the herbicides most popularly used in the study areas (García-García et al., 2016)."

    [...]

    Studies on Rats

    "A wide range of environmental pollutants, including heavy metals, insecticides, herbicides, and pesticides, can cause gut dysbiosis (Jin et al., 2015, Lin et al., 2020, Reygner et al., 2016). As suggested in our findings, there is also an increased risk of IBS precisely in pesticide-heavy areas and particularly in women. Previous research have found sexually dimorphic metabolic effect after pesticides exposures (Lukowicz et al., 2018). In this regard, #Roundup®, a glyphosate-based herbicide (#GBH) widely used in Andalusian crops, can increase the #Bacteroidetes group while decreasing the #Lactobacillaceae family in fecal samples of female rats (Lozano et al., 2018). Similarly, chronic glyphosate exposure reduces Corynebacterium, Firmicutes, Bacteroidetes, and Lactobacillus in mice following GBH administration (Aitbali et al., 2018). Exposure to fungicides such as imazalil can also alter the composition of the GM after acute and chronic administration. Specifically, in mice, imazalil increases the relative abundance of Firmicutes, Proteobacteria and Actinobacteria while decreasing the abundance of Bacteroidetes (Jin et al., 2016). Insecticides such as chlorpyrifos, diazinon and aldicarb also disrupt the GM of rats and mice (Aitbali et al., 2018, Gao et al., 2019, Gao et al., 2017, Joly et al., 2013). This modification has been associated with increased intestinal permeability and bacterial translocation in the case of chlorpyrifos (Condette et al., 2014). Diazinon inhibits several SCFA-producing genera in the Lachnospiraceae family, which operate as an energy substrate for colonic epithelial cells, altering energy harvesting in the intestinal epithelium (Gao et al., 2017)."

    Read more:
    sciencedirect.com/science/arti

    #IBS #Bayer #ToxicPesticides
    #Monocrops #Monocrap #BigAg
    #BigChem #Poison #RoundUpKills #USPol #WorldPol #Roundup #Glyphosate #Herbicides

  25. Environmental #pesticide exposure and the risk of irritable bowel syndrome: A case-control study

    Environmental Toxicology and Pharmacology
    Volume 98, March 2023, 104076
    Lola Rueda-Ruzafa, Pablo Roman, Diana Cardona, Mar Requena, Carmen Ropero-Padilla, Raquel Alarcón

    Highlights

    • The risk of irritable bowel syndrome is higher in areas of high pesticide exposure.
    • Agronomic criteria were used to categorize pesticide exposure in the study population.
    • A total of 18,807 cases of irritable bowel syndrome were studied.
    • Environmental pesticide exposure is linked to irritable bowel syndrome.

    Abstract
    The agricultural model in southern #Spain is highly productive, mainly due to the intensive cultivation under plastic. Despite strict pesticide regulation, human exposure to pesticides in the environment has been connected to an increase in diseases such as #CeliacDisease. Certain pesticides have also been associated to the disruption of the intestinal #microbiota, which has been xtied to the development of irritable bowel syndrome (IBS). A case-control study was conducted in Andalusia, south #Spain, to assess the prevalence and risk of IBS related to pesticide exposure. This research found a high prevalence of IBS in #Andalusia between 2000 and 2021 in areas with high pesticide exposure using agronomic criteria. Furthermore, the odds ratio for IBS was significantly higher in the population with high pesticide exposure. This study suggests that pesticides may be involved in IBS, whereas more research is needed to determine the role of pesticides in IBS symptomatology.

    Excerpts: "[In the locations of the study], the most commonly used insecticides are #organophosphates (primarily chlorpyrifos), N-methylcarbamates, macrocyclic lactones, #neonicotinoids, and pyrethroids. #Fungicides frequently used in plastic greenhouses include (di) thiocarbamates, conazoles, dicarboximide), anilino-pyrimidines, and copper salts. Bipyridyl (paraquat, diquat), organophosphonates (#glyphosate), chlorotriazine, and phenylurea are the herbicides most popularly used in the study areas (García-García et al., 2016)."

    [...]

    Studies on Rats

    "A wide range of environmental pollutants, including heavy metals, insecticides, herbicides, and pesticides, can cause gut dysbiosis (Jin et al., 2015, Lin et al., 2020, Reygner et al., 2016). As suggested in our findings, there is also an increased risk of IBS precisely in pesticide-heavy areas and particularly in women. Previous research have found sexually dimorphic metabolic effect after pesticides exposures (Lukowicz et al., 2018). In this regard, #Roundup®, a glyphosate-based herbicide (#GBH) widely used in Andalusian crops, can increase the #Bacteroidetes group while decreasing the #Lactobacillaceae family in fecal samples of female rats (Lozano et al., 2018). Similarly, chronic glyphosate exposure reduces Corynebacterium, Firmicutes, Bacteroidetes, and Lactobacillus in mice following GBH administration (Aitbali et al., 2018). Exposure to fungicides such as imazalil can also alter the composition of the GM after acute and chronic administration. Specifically, in mice, imazalil increases the relative abundance of Firmicutes, Proteobacteria and Actinobacteria while decreasing the abundance of Bacteroidetes (Jin et al., 2016). Insecticides such as chlorpyrifos, diazinon and aldicarb also disrupt the GM of rats and mice (Aitbali et al., 2018, Gao et al., 2019, Gao et al., 2017, Joly et al., 2013). This modification has been associated with increased intestinal permeability and bacterial translocation in the case of chlorpyrifos (Condette et al., 2014). Diazinon inhibits several SCFA-producing genera in the Lachnospiraceae family, which operate as an energy substrate for colonic epithelial cells, altering energy harvesting in the intestinal epithelium (Gao et al., 2017)."

    Read more:
    sciencedirect.com/science/arti

    #IBS #Bayer #ToxicPesticides
    #Monocrops #Monocrap #BigAg
    #BigChem #Poison #RoundUpKills #USPol #WorldPol #Roundup #Glyphosate #Herbicides

  26. Environmental #pesticide exposure and the risk of irritable bowel syndrome: A case-control study

    Environmental Toxicology and Pharmacology
    Volume 98, March 2023, 104076
    Lola Rueda-Ruzafa, Pablo Roman, Diana Cardona, Mar Requena, Carmen Ropero-Padilla, Raquel Alarcón

    Highlights

    • The risk of irritable bowel syndrome is higher in areas of high pesticide exposure.
    • Agronomic criteria were used to categorize pesticide exposure in the study population.
    • A total of 18,807 cases of irritable bowel syndrome were studied.
    • Environmental pesticide exposure is linked to irritable bowel syndrome.

    Abstract
    The agricultural model in southern #Spain is highly productive, mainly due to the intensive cultivation under plastic. Despite strict pesticide regulation, human exposure to pesticides in the environment has been connected to an increase in diseases such as #CeliacDisease. Certain pesticides have also been associated to the disruption of the intestinal #microbiota, which has been xtied to the development of irritable bowel syndrome (IBS). A case-control study was conducted in Andalusia, south #Spain, to assess the prevalence and risk of IBS related to pesticide exposure. This research found a high prevalence of IBS in #Andalusia between 2000 and 2021 in areas with high pesticide exposure using agronomic criteria. Furthermore, the odds ratio for IBS was significantly higher in the population with high pesticide exposure. This study suggests that pesticides may be involved in IBS, whereas more research is needed to determine the role of pesticides in IBS symptomatology.

    Excerpts: "[In the locations of the study], the most commonly used insecticides are #organophosphates (primarily chlorpyrifos), N-methylcarbamates, macrocyclic lactones, #neonicotinoids, and pyrethroids. #Fungicides frequently used in plastic greenhouses include (di) thiocarbamates, conazoles, dicarboximide), anilino-pyrimidines, and copper salts. Bipyridyl (paraquat, diquat), organophosphonates (#glyphosate), chlorotriazine, and phenylurea are the herbicides most popularly used in the study areas (García-García et al., 2016)."

    [...]

    Studies on Rats

    "A wide range of environmental pollutants, including heavy metals, insecticides, herbicides, and pesticides, can cause gut dysbiosis (Jin et al., 2015, Lin et al., 2020, Reygner et al., 2016). As suggested in our findings, there is also an increased risk of IBS precisely in pesticide-heavy areas and particularly in women. Previous research have found sexually dimorphic metabolic effect after pesticides exposures (Lukowicz et al., 2018). In this regard, #Roundup®, a glyphosate-based herbicide (#GBH) widely used in Andalusian crops, can increase the #Bacteroidetes group while decreasing the #Lactobacillaceae family in fecal samples of female rats (Lozano et al., 2018). Similarly, chronic glyphosate exposure reduces Corynebacterium, Firmicutes, Bacteroidetes, and Lactobacillus in mice following GBH administration (Aitbali et al., 2018). Exposure to fungicides such as imazalil can also alter the composition of the GM after acute and chronic administration. Specifically, in mice, imazalil increases the relative abundance of Firmicutes, Proteobacteria and Actinobacteria while decreasing the abundance of Bacteroidetes (Jin et al., 2016). Insecticides such as chlorpyrifos, diazinon and aldicarb also disrupt the GM of rats and mice (Aitbali et al., 2018, Gao et al., 2019, Gao et al., 2017, Joly et al., 2013). This modification has been associated with increased intestinal permeability and bacterial translocation in the case of chlorpyrifos (Condette et al., 2014). Diazinon inhibits several SCFA-producing genera in the Lachnospiraceae family, which operate as an energy substrate for colonic epithelial cells, altering energy harvesting in the intestinal epithelium (Gao et al., 2017)."

    Read more:
    sciencedirect.com/science/arti

    #IBS #Bayer #ToxicPesticides
    #Monocrops #Monocrap #BigAg
    #BigChem #Poison #RoundUpKills #USPol #WorldPol #Roundup #Glyphosate #Herbicides

  27. Happy Birthday to Colin Abrahall, leadsinger of long-lived street punk band GBH, born on this day in 1961

    GBH - Sick Boy (live)

    #punk #punks #punkrock #streetpunk #colinabrahall #gbh #history #punkrockhistory #otd

  28. Happy Birthday to Colin Abrahall, British musican and leadsinger of long-lived street punk band GBH, born on this day in 1961

    Photo by Alison Braun

    #punk #punks #punkrock #streetpunk #colinabrahall #gbh #history #punkrockhistory #otd

  29. 43 years ago
    British street punk band GBH, group portrait featuring large mohicans, Covent Garden, United Kingdom, October 1982.

    Line up includes: Colin Abrahall, Colin 'Jock' Blyth, Ross Lomas and Andrew 'Wilf' Williams. Photo by Erica Echenberg

    #punkrock #gbh #punkrockhistory

  30. 🌞 Hello #fediverse! This is #GBH News bringing you the world from #Boston. It's 58F at Logan Airport and visibility is 10mi.

    The government is shut down. Trump has vowed to halt funding to blue states and "Democrat agencies."

    The great naturalist and advocate for conservation Jane Goodall has died. She was 91.

    The Trump administration wants MIT, other universities to sign "compact" in exchange for funding.