#fungicides — Public Fediverse posts

#Maine - The Annual Obsolete #Pesticide Program - Deadline for registration is October 5, 2026

"Registration is now open for the 2026 Obsolete Pesticide Collection Program.
2026 Obsolete Pesticide Collection

The Maine Board of Pesticides Control and the Maine Department of Environmental Protection offer Maine residents a free, safe, and environmentally responsible way to dispose of obsolete, unusable, or unwanted pesticides. Collected materials are transported to licensed out-of-state hazardous waste disposal facilities.

The program is open to Maine resident homeowners and family-owned farms.

The program does not accept commercial pesticide waste. Commercial applicators, businesses, and other commercial entities are responsible for disposing of pesticide waste through a licensed hazardous waste contractor.

What can be collected?

The program accepts obsolete or unwanted pesticides, including but not limited to:

#Herbicides
#Insecticides
#Rodenticides
#Fungicides
Disinfectants
Spray adjuvants

Materials may be accepted whether they are unused, banned, no longer usable, frozen, caked, or otherwise unsuitable for use.

Collection Events

One-day collection events will be held in November 2026 at the following locations:

#PresqueIsleME
#BangorME
#AugustaME
#PortlandME

For security reasons, event dates, times, and specific collection locations are provided only to registered participants. Pre-registration is required. Drop-in participants cannot be accepted.
Need to Dispose of Pesticides Sooner?

If you need to dispose of pesticides before the annual collection program, contact your local Maine Department of Environmental Protection (DEP) office for guidance. Many Maine municipalities also host #HouseholdHazardousWaste Collection events during the summer, where residents can safely dispose of pesticides and other household hazardous wastes. Contact your local town office for information about events in your area or see our Disposal Options page for additional guidance. The Board of Pesticides Control cannot provide emergency hazardous waste disposal. If you have an immediate disposal need, contact your local DEP office or a licensed hazardous waste contractor.

Registration Reminder

Pre-registration is required for all participants. Registrations must be submitted by the individual currently possessing the pesticides. Materials delivered on behalf of another person or business cannot be accepted. Registration Deadline: Monday, October 5, 2026.

FMI:
https://www.maine.gov/dacf/php/pesticides/public/obsolete_pesticide_collection.shtml

#SolarPunkSunday
#MaineEvents #PesticideDisposal #Pesticides #Chemicals #FallCleanups #WasteDisposal

#Maine - The Annual Obsolete #Pesticide Program - Deadline for registration is October 5, 2026

"Registration is now open for the 2026 Obsolete Pesticide Collection Program.
2026 Obsolete Pesticide Collection

The Maine Board of Pesticides Control and the Maine Department of Environmental Protection offer Maine residents a free, safe, and environmentally responsible way to dispose of obsolete, unusable, or unwanted pesticides. Collected materials are transported to licensed out-of-state hazardous waste disposal facilities.

The program is open to Maine resident homeowners and family-owned farms.

The program does not accept commercial pesticide waste. Commercial applicators, businesses, and other commercial entities are responsible for disposing of pesticide waste through a licensed hazardous waste contractor.

What can be collected?

The program accepts obsolete or unwanted pesticides, including but not limited to:

#Herbicides
#Insecticides
#Rodenticides
#Fungicides
Disinfectants
Spray adjuvants

Materials may be accepted whether they are unused, banned, no longer usable, frozen, caked, or otherwise unsuitable for use.

Collection Events

One-day collection events will be held in November 2026 at the following locations:

#PresqueIsleME
#BangorME
#AugustaME
#PortlandME

For security reasons, event dates, times, and specific collection locations are provided only to registered participants. Pre-registration is required. Drop-in participants cannot be accepted.
Need to Dispose of Pesticides Sooner?

If you need to dispose of pesticides before the annual collection program, contact your local Maine Department of Environmental Protection (DEP) office for guidance. Many Maine municipalities also host #HouseholdHazardousWaste Collection events during the summer, where residents can safely dispose of pesticides and other household hazardous wastes. Contact your local town office for information about events in your area or see our Disposal Options page for additional guidance. The Board of Pesticides Control cannot provide emergency hazardous waste disposal. If you have an immediate disposal need, contact your local DEP office or a licensed hazardous waste contractor.

Registration Reminder

Pre-registration is required for all participants. Registrations must be submitted by the individual currently possessing the pesticides. Materials delivered on behalf of another person or business cannot be accepted. Registration Deadline: Monday, October 5, 2026.

FMI:
https://www.maine.gov/dacf/php/pesticides/public/obsolete_pesticide_collection.shtml

#SolarPunkSunday
#MaineEvents #PesticideDisposal #Pesticides #Chemicals #FallCleanups #WasteDisposal

#Maine - The Annual Obsolete #Pesticide Program - Deadline for registration is October 5, 2026

"Registration is now open for the 2026 Obsolete Pesticide Collection Program.
2026 Obsolete Pesticide Collection

The Maine Board of Pesticides Control and the Maine Department of Environmental Protection offer Maine residents a free, safe, and environmentally responsible way to dispose of obsolete, unusable, or unwanted pesticides. Collected materials are transported to licensed out-of-state hazardous waste disposal facilities.

The program is open to Maine resident homeowners and family-owned farms.

The program does not accept commercial pesticide waste. Commercial applicators, businesses, and other commercial entities are responsible for disposing of pesticide waste through a licensed hazardous waste contractor.

What can be collected?

The program accepts obsolete or unwanted pesticides, including but not limited to:

#Herbicides
#Insecticides
#Rodenticides
#Fungicides
Disinfectants
Spray adjuvants

Materials may be accepted whether they are unused, banned, no longer usable, frozen, caked, or otherwise unsuitable for use.

Collection Events

One-day collection events will be held in November 2026 at the following locations:

#PresqueIsleME
#BangorME
#AugustaME
#PortlandME

For security reasons, event dates, times, and specific collection locations are provided only to registered participants. Pre-registration is required. Drop-in participants cannot be accepted.
Need to Dispose of Pesticides Sooner?

If you need to dispose of pesticides before the annual collection program, contact your local Maine Department of Environmental Protection (DEP) office for guidance. Many Maine municipalities also host #HouseholdHazardousWaste Collection events during the summer, where residents can safely dispose of pesticides and other household hazardous wastes. Contact your local town office for information about events in your area or see our Disposal Options page for additional guidance. The Board of Pesticides Control cannot provide emergency hazardous waste disposal. If you have an immediate disposal need, contact your local DEP office or a licensed hazardous waste contractor.

Registration Reminder

Pre-registration is required for all participants. Registrations must be submitted by the individual currently possessing the pesticides. Materials delivered on behalf of another person or business cannot be accepted. Registration Deadline: Monday, October 5, 2026.

FMI:
https://www.maine.gov/dacf/php/pesticides/public/obsolete_pesticide_collection.shtml

#SolarPunkSunday
#MaineEvents #PesticideDisposal #Pesticides #Chemicals #FallCleanups #WasteDisposal

#Maine - The Annual Obsolete #Pesticide Program - Deadline for registration is October 5, 2026

"Registration is now open for the 2026 Obsolete Pesticide Collection Program.
2026 Obsolete Pesticide Collection

The Maine Board of Pesticides Control and the Maine Department of Environmental Protection offer Maine residents a free, safe, and environmentally responsible way to dispose of obsolete, unusable, or unwanted pesticides. Collected materials are transported to licensed out-of-state hazardous waste disposal facilities.

The program is open to Maine resident homeowners and family-owned farms.

The program does not accept commercial pesticide waste. Commercial applicators, businesses, and other commercial entities are responsible for disposing of pesticide waste through a licensed hazardous waste contractor.

What can be collected?

The program accepts obsolete or unwanted pesticides, including but not limited to:

#Herbicides
#Insecticides
#Rodenticides
#Fungicides
Disinfectants
Spray adjuvants

Materials may be accepted whether they are unused, banned, no longer usable, frozen, caked, or otherwise unsuitable for use.

Collection Events

One-day collection events will be held in November 2026 at the following locations:

#PresqueIsleME
#BangorME
#AugustaME
#PortlandME

For security reasons, event dates, times, and specific collection locations are provided only to registered participants. Pre-registration is required. Drop-in participants cannot be accepted.
Need to Dispose of Pesticides Sooner?

If you need to dispose of pesticides before the annual collection program, contact your local Maine Department of Environmental Protection (DEP) office for guidance. Many Maine municipalities also host #HouseholdHazardousWaste Collection events during the summer, where residents can safely dispose of pesticides and other household hazardous wastes. Contact your local town office for information about events in your area or see our Disposal Options page for additional guidance. The Board of Pesticides Control cannot provide emergency hazardous waste disposal. If you have an immediate disposal need, contact your local DEP office or a licensed hazardous waste contractor.

Registration Reminder

Pre-registration is required for all participants. Registrations must be submitted by the individual currently possessing the pesticides. Materials delivered on behalf of another person or business cannot be accepted. Registration Deadline: Monday, October 5, 2026.

FMI:
https://www.maine.gov/dacf/php/pesticides/public/obsolete_pesticide_collection.shtml

#SolarPunkSunday
#MaineEvents #PesticideDisposal #Pesticides #Chemicals #FallCleanups #WasteDisposal

#Maine - The Annual Obsolete #Pesticide Program - Deadline for registration is October 5, 2026

"Registration is now open for the 2026 Obsolete Pesticide Collection Program.
2026 Obsolete Pesticide Collection

The Maine Board of Pesticides Control and the Maine Department of Environmental Protection offer Maine residents a free, safe, and environmentally responsible way to dispose of obsolete, unusable, or unwanted pesticides. Collected materials are transported to licensed out-of-state hazardous waste disposal facilities.

The program is open to Maine resident homeowners and family-owned farms.

The program does not accept commercial pesticide waste. Commercial applicators, businesses, and other commercial entities are responsible for disposing of pesticide waste through a licensed hazardous waste contractor.

What can be collected?

The program accepts obsolete or unwanted pesticides, including but not limited to:

#Herbicides
#Insecticides
#Rodenticides
#Fungicides
Disinfectants
Spray adjuvants

Materials may be accepted whether they are unused, banned, no longer usable, frozen, caked, or otherwise unsuitable for use.

Collection Events

One-day collection events will be held in November 2026 at the following locations:

#PresqueIsleME
#BangorME
#AugustaME
#PortlandME

For security reasons, event dates, times, and specific collection locations are provided only to registered participants. Pre-registration is required. Drop-in participants cannot be accepted.
Need to Dispose of Pesticides Sooner?

If you need to dispose of pesticides before the annual collection program, contact your local Maine Department of Environmental Protection (DEP) office for guidance. Many Maine municipalities also host #HouseholdHazardousWaste Collection events during the summer, where residents can safely dispose of pesticides and other household hazardous wastes. Contact your local town office for information about events in your area or see our Disposal Options page for additional guidance. The Board of Pesticides Control cannot provide emergency hazardous waste disposal. If you have an immediate disposal need, contact your local DEP office or a licensed hazardous waste contractor.

Registration Reminder

Pre-registration is required for all participants. Registrations must be submitted by the individual currently possessing the pesticides. Materials delivered on behalf of another person or business cannot be accepted. Registration Deadline: Monday, October 5, 2026.

FMI:
https://www.maine.gov/dacf/php/pesticides/public/obsolete_pesticide_collection.shtml

#SolarPunkSunday
#MaineEvents #PesticideDisposal #Pesticides #Chemicals #FallCleanups #WasteDisposal

Pesticide exposure at work may increase motor neurone disease risk – new study

"A new study, published today, has found that being exposed to pesticide at work can increase the risk of developing ALS (amyotrophic lateral sclerosis) by 61–71%. The study brings together the findings of eight other studies – but not all of them assess risk in the same way. Here’s why we need to interpret the findings with caution....Overall, the study supports the case that being exposed to pesticide at work increases your risk of developing ALS." >>
https://theconversation.com/pesticide-exposure-at-work-may-increase-motor-neurone-disease-risk-new-study-289043
#pesticides #fungicides #herbicides #insecticides #harm #OHS #work #NeuroDegenerativeDiseases #conservation #weeding #councils #HorticulturalIndustry #ALS

#Cyclospora Spreads Through Human Feces. How Did It Get Into Our Food Supply?

The large number of cases suggests that excrement entered the food system on a “surprising scale.”

By Alice Callahan and Caroline Hopkins Legaspi
July 21, 2026

Excerpt: "Several cyclospora outbreaks linked to raspberries in the late 1990s illustrated one way the parasite can contaminate fresh produce, said Melvin Kramer, an epidemiologist who worked in several state and local public health departments before founding a food safety consulting group.

"In 1996, after collecting detailed food histories from people sickened with cyclospora, investigators traced the illnesses to raspberries from a few farms in Guatemala. There, investigators determined it was likely that the #insecticides and #fungicides sprayed onto the berries had been mixed with #ContaminatedWater. The farms had sourced the water from wells or a nearby river, both of which were vulnerable to #runoff from latrines, especially during the rainy season. Although the water was filtered, the filter removed only debris, not microbes like cyclospora.

"Before this year, the largest outbreak in the United States in recent history occurred in the summer of 2020, sickening 701 people in 14 states and hospitalizing 38. Federal officials linked it to Fresh Express bagged salads containing iceberg lettuce, red cabbage and carrots. They traced at least some of that produce to a farm in South Florida and detected cyclospora in a nearby #WaterCanal that had been used to irrigate crops on the farm. Later, genetic analysis confirmed that the cyclospora found in the canal water matched that found in people sickened in the outbreak, said Frank Yiannas, who was a top official at the #FDA from 2018 to 2023."

Archived version:
https://archive.ph/r7zv4

#WaterIsLife #Cyclosporasis #FoodContamination #BigAg #GrowYourOwnFood #WaterContamination

Environmental #pesticide exposure and the risk of irritable bowel syndrome: A case-control study

Environmental Toxicology and Pharmacology
Volume 98, March 2023, 104076
Lola Rueda-Ruzafa, Pablo Roman, Diana Cardona, Mar Requena, Carmen Ropero-Padilla, Raquel Alarcón

Highlights

• The risk of irritable bowel syndrome is higher in areas of high pesticide exposure.
• Agronomic criteria were used to categorize pesticide exposure in the study population.
• A total of 18,807 cases of irritable bowel syndrome were studied.
• Environmental pesticide exposure is linked to irritable bowel syndrome.

Abstract
The agricultural model in southern #Spain is highly productive, mainly due to the intensive cultivation under plastic. Despite strict pesticide regulation, human exposure to pesticides in the environment has been connected to an increase in diseases such as #CeliacDisease. Certain pesticides have also been associated to the disruption of the intestinal #microbiota, which has been xtied to the development of irritable bowel syndrome (IBS). A case-control study was conducted in Andalusia, south #Spain, to assess the prevalence and risk of IBS related to pesticide exposure. This research found a high prevalence of IBS in #Andalusia between 2000 and 2021 in areas with high pesticide exposure using agronomic criteria. Furthermore, the odds ratio for IBS was significantly higher in the population with high pesticide exposure. This study suggests that pesticides may be involved in IBS, whereas more research is needed to determine the role of pesticides in IBS symptomatology.

Excerpts: "[In the locations of the study], the most commonly used insecticides are #organophosphates (primarily chlorpyrifos), N-methylcarbamates, macrocyclic lactones, #neonicotinoids, and pyrethroids. #Fungicides frequently used in plastic greenhouses include (di) thiocarbamates, conazoles, dicarboximide), anilino-pyrimidines, and copper salts. Bipyridyl (paraquat, diquat), organophosphonates (#glyphosate), chlorotriazine, and phenylurea are the herbicides most popularly used in the study areas (García-García et al., 2016)."

[...]

Studies on Rats

"A wide range of environmental pollutants, including heavy metals, insecticides, herbicides, and pesticides, can cause gut dysbiosis (Jin et al., 2015, Lin et al., 2020, Reygner et al., 2016). As suggested in our findings, there is also an increased risk of IBS precisely in pesticide-heavy areas and particularly in women. Previous research have found sexually dimorphic metabolic effect after pesticides exposures (Lukowicz et al., 2018). In this regard, #Roundup®, a glyphosate-based herbicide (#GBH) widely used in Andalusian crops, can increase the #Bacteroidetes group while decreasing the #Lactobacillaceae family in fecal samples of female rats (Lozano et al., 2018). Similarly, chronic glyphosate exposure reduces Corynebacterium, Firmicutes, Bacteroidetes, and Lactobacillus in mice following GBH administration (Aitbali et al., 2018). Exposure to fungicides such as imazalil can also alter the composition of the GM after acute and chronic administration. Specifically, in mice, imazalil increases the relative abundance of Firmicutes, Proteobacteria and Actinobacteria while decreasing the abundance of Bacteroidetes (Jin et al., 2016). Insecticides such as chlorpyrifos, diazinon and aldicarb also disrupt the GM of rats and mice (Aitbali et al., 2018, Gao et al., 2019, Gao et al., 2017, Joly et al., 2013). This modification has been associated with increased intestinal permeability and bacterial translocation in the case of chlorpyrifos (Condette et al., 2014). Diazinon inhibits several SCFA-producing genera in the Lachnospiraceae family, which operate as an energy substrate for colonic epithelial cells, altering energy harvesting in the intestinal epithelium (Gao et al., 2017)."

Read more:
https://www.sciencedirect.com/science/article/pii/S1382668923000170

#IBS #Bayer #ToxicPesticides
#Monocrops #Monocrap #BigAg
#BigChem #Poison #RoundUpKills #USPol #WorldPol #Roundup #Glyphosate #Herbicides

Environmental #pesticide exposure and the risk of irritable bowel syndrome: A case-control study

Environmental Toxicology and Pharmacology
Volume 98, March 2023, 104076
Lola Rueda-Ruzafa, Pablo Roman, Diana Cardona, Mar Requena, Carmen Ropero-Padilla, Raquel Alarcón

Highlights

• The risk of irritable bowel syndrome is higher in areas of high pesticide exposure.
• Agronomic criteria were used to categorize pesticide exposure in the study population.
• A total of 18,807 cases of irritable bowel syndrome were studied.
• Environmental pesticide exposure is linked to irritable bowel syndrome.

Abstract
The agricultural model in southern #Spain is highly productive, mainly due to the intensive cultivation under plastic. Despite strict pesticide regulation, human exposure to pesticides in the environment has been connected to an increase in diseases such as #CeliacDisease. Certain pesticides have also been associated to the disruption of the intestinal #microbiota, which has been xtied to the development of irritable bowel syndrome (IBS). A case-control study was conducted in Andalusia, south #Spain, to assess the prevalence and risk of IBS related to pesticide exposure. This research found a high prevalence of IBS in #Andalusia between 2000 and 2021 in areas with high pesticide exposure using agronomic criteria. Furthermore, the odds ratio for IBS was significantly higher in the population with high pesticide exposure. This study suggests that pesticides may be involved in IBS, whereas more research is needed to determine the role of pesticides in IBS symptomatology.

Excerpts: "[In the locations of the study], the most commonly used insecticides are #organophosphates (primarily chlorpyrifos), N-methylcarbamates, macrocyclic lactones, #neonicotinoids, and pyrethroids. #Fungicides frequently used in plastic greenhouses include (di) thiocarbamates, conazoles, dicarboximide), anilino-pyrimidines, and copper salts. Bipyridyl (paraquat, diquat), organophosphonates (#glyphosate), chlorotriazine, and phenylurea are the herbicides most popularly used in the study areas (García-García et al., 2016)."

[...]

Studies on Rats

"A wide range of environmental pollutants, including heavy metals, insecticides, herbicides, and pesticides, can cause gut dysbiosis (Jin et al., 2015, Lin et al., 2020, Reygner et al., 2016). As suggested in our findings, there is also an increased risk of IBS precisely in pesticide-heavy areas and particularly in women. Previous research have found sexually dimorphic metabolic effect after pesticides exposures (Lukowicz et al., 2018). In this regard, #Roundup®, a glyphosate-based herbicide (#GBH) widely used in Andalusian crops, can increase the #Bacteroidetes group while decreasing the #Lactobacillaceae family in fecal samples of female rats (Lozano et al., 2018). Similarly, chronic glyphosate exposure reduces Corynebacterium, Firmicutes, Bacteroidetes, and Lactobacillus in mice following GBH administration (Aitbali et al., 2018). Exposure to fungicides such as imazalil can also alter the composition of the GM after acute and chronic administration. Specifically, in mice, imazalil increases the relative abundance of Firmicutes, Proteobacteria and Actinobacteria while decreasing the abundance of Bacteroidetes (Jin et al., 2016). Insecticides such as chlorpyrifos, diazinon and aldicarb also disrupt the GM of rats and mice (Aitbali et al., 2018, Gao et al., 2019, Gao et al., 2017, Joly et al., 2013). This modification has been associated with increased intestinal permeability and bacterial translocation in the case of chlorpyrifos (Condette et al., 2014). Diazinon inhibits several SCFA-producing genera in the Lachnospiraceae family, which operate as an energy substrate for colonic epithelial cells, altering energy harvesting in the intestinal epithelium (Gao et al., 2017)."

Read more:
https://www.sciencedirect.com/science/article/pii/S1382668923000170

#IBS #Bayer #ToxicPesticides
#Monocrops #Monocrap #BigAg
#BigChem #Poison #RoundUpKills #USPol #WorldPol #Roundup #Glyphosate #Herbicides

Environmental #pesticide exposure and the risk of irritable bowel syndrome: A case-control study

Environmental Toxicology and Pharmacology
Volume 98, March 2023, 104076
Lola Rueda-Ruzafa, Pablo Roman, Diana Cardona, Mar Requena, Carmen Ropero-Padilla, Raquel Alarcón

Highlights

• The risk of irritable bowel syndrome is higher in areas of high pesticide exposure.
• Agronomic criteria were used to categorize pesticide exposure in the study population.
• A total of 18,807 cases of irritable bowel syndrome were studied.
• Environmental pesticide exposure is linked to irritable bowel syndrome.

Abstract
The agricultural model in southern #Spain is highly productive, mainly due to the intensive cultivation under plastic. Despite strict pesticide regulation, human exposure to pesticides in the environment has been connected to an increase in diseases such as #CeliacDisease. Certain pesticides have also been associated to the disruption of the intestinal #microbiota, which has been xtied to the development of irritable bowel syndrome (IBS). A case-control study was conducted in Andalusia, south #Spain, to assess the prevalence and risk of IBS related to pesticide exposure. This research found a high prevalence of IBS in #Andalusia between 2000 and 2021 in areas with high pesticide exposure using agronomic criteria. Furthermore, the odds ratio for IBS was significantly higher in the population with high pesticide exposure. This study suggests that pesticides may be involved in IBS, whereas more research is needed to determine the role of pesticides in IBS symptomatology.

Excerpts: "[In the locations of the study], the most commonly used insecticides are #organophosphates (primarily chlorpyrifos), N-methylcarbamates, macrocyclic lactones, #neonicotinoids, and pyrethroids. #Fungicides frequently used in plastic greenhouses include (di) thiocarbamates, conazoles, dicarboximide), anilino-pyrimidines, and copper salts. Bipyridyl (paraquat, diquat), organophosphonates (#glyphosate), chlorotriazine, and phenylurea are the herbicides most popularly used in the study areas (García-García et al., 2016)."

[...]

Studies on Rats

"A wide range of environmental pollutants, including heavy metals, insecticides, herbicides, and pesticides, can cause gut dysbiosis (Jin et al., 2015, Lin et al., 2020, Reygner et al., 2016). As suggested in our findings, there is also an increased risk of IBS precisely in pesticide-heavy areas and particularly in women. Previous research have found sexually dimorphic metabolic effect after pesticides exposures (Lukowicz et al., 2018). In this regard, #Roundup®, a glyphosate-based herbicide (#GBH) widely used in Andalusian crops, can increase the #Bacteroidetes group while decreasing the #Lactobacillaceae family in fecal samples of female rats (Lozano et al., 2018). Similarly, chronic glyphosate exposure reduces Corynebacterium, Firmicutes, Bacteroidetes, and Lactobacillus in mice following GBH administration (Aitbali et al., 2018). Exposure to fungicides such as imazalil can also alter the composition of the GM after acute and chronic administration. Specifically, in mice, imazalil increases the relative abundance of Firmicutes, Proteobacteria and Actinobacteria while decreasing the abundance of Bacteroidetes (Jin et al., 2016). Insecticides such as chlorpyrifos, diazinon and aldicarb also disrupt the GM of rats and mice (Aitbali et al., 2018, Gao et al., 2019, Gao et al., 2017, Joly et al., 2013). This modification has been associated with increased intestinal permeability and bacterial translocation in the case of chlorpyrifos (Condette et al., 2014). Diazinon inhibits several SCFA-producing genera in the Lachnospiraceae family, which operate as an energy substrate for colonic epithelial cells, altering energy harvesting in the intestinal epithelium (Gao et al., 2017)."

Read more:
https://www.sciencedirect.com/science/article/pii/S1382668923000170

#IBS #Bayer #ToxicPesticides
#Monocrops #Monocrap #BigAg
#BigChem #Poison #RoundUpKills #USPol #WorldPol #Roundup #Glyphosate #Herbicides

Environmental #pesticide exposure and the risk of irritable bowel syndrome: A case-control study

Environmental Toxicology and Pharmacology
Volume 98, March 2023, 104076
Lola Rueda-Ruzafa, Pablo Roman, Diana Cardona, Mar Requena, Carmen Ropero-Padilla, Raquel Alarcón

Highlights

• The risk of irritable bowel syndrome is higher in areas of high pesticide exposure.
• Agronomic criteria were used to categorize pesticide exposure in the study population.
• A total of 18,807 cases of irritable bowel syndrome were studied.
• Environmental pesticide exposure is linked to irritable bowel syndrome.

Abstract
The agricultural model in southern #Spain is highly productive, mainly due to the intensive cultivation under plastic. Despite strict pesticide regulation, human exposure to pesticides in the environment has been connected to an increase in diseases such as #CeliacDisease. Certain pesticides have also been associated to the disruption of the intestinal #microbiota, which has been xtied to the development of irritable bowel syndrome (IBS). A case-control study was conducted in Andalusia, south #Spain, to assess the prevalence and risk of IBS related to pesticide exposure. This research found a high prevalence of IBS in #Andalusia between 2000 and 2021 in areas with high pesticide exposure using agronomic criteria. Furthermore, the odds ratio for IBS was significantly higher in the population with high pesticide exposure. This study suggests that pesticides may be involved in IBS, whereas more research is needed to determine the role of pesticides in IBS symptomatology.

Excerpts: "[In the locations of the study], the most commonly used insecticides are #organophosphates (primarily chlorpyrifos), N-methylcarbamates, macrocyclic lactones, #neonicotinoids, and pyrethroids. #Fungicides frequently used in plastic greenhouses include (di) thiocarbamates, conazoles, dicarboximide), anilino-pyrimidines, and copper salts. Bipyridyl (paraquat, diquat), organophosphonates (#glyphosate), chlorotriazine, and phenylurea are the herbicides most popularly used in the study areas (García-García et al., 2016)."

[...]

Studies on Rats

"A wide range of environmental pollutants, including heavy metals, insecticides, herbicides, and pesticides, can cause gut dysbiosis (Jin et al., 2015, Lin et al., 2020, Reygner et al., 2016). As suggested in our findings, there is also an increased risk of IBS precisely in pesticide-heavy areas and particularly in women. Previous research have found sexually dimorphic metabolic effect after pesticides exposures (Lukowicz et al., 2018). In this regard, #Roundup®, a glyphosate-based herbicide (#GBH) widely used in Andalusian crops, can increase the #Bacteroidetes group while decreasing the #Lactobacillaceae family in fecal samples of female rats (Lozano et al., 2018). Similarly, chronic glyphosate exposure reduces Corynebacterium, Firmicutes, Bacteroidetes, and Lactobacillus in mice following GBH administration (Aitbali et al., 2018). Exposure to fungicides such as imazalil can also alter the composition of the GM after acute and chronic administration. Specifically, in mice, imazalil increases the relative abundance of Firmicutes, Proteobacteria and Actinobacteria while decreasing the abundance of Bacteroidetes (Jin et al., 2016). Insecticides such as chlorpyrifos, diazinon and aldicarb also disrupt the GM of rats and mice (Aitbali et al., 2018, Gao et al., 2019, Gao et al., 2017, Joly et al., 2013). This modification has been associated with increased intestinal permeability and bacterial translocation in the case of chlorpyrifos (Condette et al., 2014). Diazinon inhibits several SCFA-producing genera in the Lachnospiraceae family, which operate as an energy substrate for colonic epithelial cells, altering energy harvesting in the intestinal epithelium (Gao et al., 2017)."

Read more:
https://www.sciencedirect.com/science/article/pii/S1382668923000170

#IBS #Bayer #ToxicPesticides
#Monocrops #Monocrap #BigAg
#BigChem #Poison #RoundUpKills #USPol #WorldPol #Roundup #Glyphosate #Herbicides

Environmental #pesticide exposure and the risk of irritable bowel syndrome: A case-control study

Environmental Toxicology and Pharmacology
Volume 98, March 2023, 104076
Lola Rueda-Ruzafa, Pablo Roman, Diana Cardona, Mar Requena, Carmen Ropero-Padilla, Raquel Alarcón

Highlights

• The risk of irritable bowel syndrome is higher in areas of high pesticide exposure.
• Agronomic criteria were used to categorize pesticide exposure in the study population.
• A total of 18,807 cases of irritable bowel syndrome were studied.
• Environmental pesticide exposure is linked to irritable bowel syndrome.

Abstract
The agricultural model in southern #Spain is highly productive, mainly due to the intensive cultivation under plastic. Despite strict pesticide regulation, human exposure to pesticides in the environment has been connected to an increase in diseases such as #CeliacDisease. Certain pesticides have also been associated to the disruption of the intestinal #microbiota, which has been xtied to the development of irritable bowel syndrome (IBS). A case-control study was conducted in Andalusia, south #Spain, to assess the prevalence and risk of IBS related to pesticide exposure. This research found a high prevalence of IBS in #Andalusia between 2000 and 2021 in areas with high pesticide exposure using agronomic criteria. Furthermore, the odds ratio for IBS was significantly higher in the population with high pesticide exposure. This study suggests that pesticides may be involved in IBS, whereas more research is needed to determine the role of pesticides in IBS symptomatology.

Excerpts: "[In the locations of the study], the most commonly used insecticides are #organophosphates (primarily chlorpyrifos), N-methylcarbamates, macrocyclic lactones, #neonicotinoids, and pyrethroids. #Fungicides frequently used in plastic greenhouses include (di) thiocarbamates, conazoles, dicarboximide), anilino-pyrimidines, and copper salts. Bipyridyl (paraquat, diquat), organophosphonates (#glyphosate), chlorotriazine, and phenylurea are the herbicides most popularly used in the study areas (García-García et al., 2016)."

[...]

Studies on Rats

"A wide range of environmental pollutants, including heavy metals, insecticides, herbicides, and pesticides, can cause gut dysbiosis (Jin et al., 2015, Lin et al., 2020, Reygner et al., 2016). As suggested in our findings, there is also an increased risk of IBS precisely in pesticide-heavy areas and particularly in women. Previous research have found sexually dimorphic metabolic effect after pesticides exposures (Lukowicz et al., 2018). In this regard, #Roundup®, a glyphosate-based herbicide (#GBH) widely used in Andalusian crops, can increase the #Bacteroidetes group while decreasing the #Lactobacillaceae family in fecal samples of female rats (Lozano et al., 2018). Similarly, chronic glyphosate exposure reduces Corynebacterium, Firmicutes, Bacteroidetes, and Lactobacillus in mice following GBH administration (Aitbali et al., 2018). Exposure to fungicides such as imazalil can also alter the composition of the GM after acute and chronic administration. Specifically, in mice, imazalil increases the relative abundance of Firmicutes, Proteobacteria and Actinobacteria while decreasing the abundance of Bacteroidetes (Jin et al., 2016). Insecticides such as chlorpyrifos, diazinon and aldicarb also disrupt the GM of rats and mice (Aitbali et al., 2018, Gao et al., 2019, Gao et al., 2017, Joly et al., 2013). This modification has been associated with increased intestinal permeability and bacterial translocation in the case of chlorpyrifos (Condette et al., 2014). Diazinon inhibits several SCFA-producing genera in the Lachnospiraceae family, which operate as an energy substrate for colonic epithelial cells, altering energy harvesting in the intestinal epithelium (Gao et al., 2017)."

Read more:
https://www.sciencedirect.com/science/article/pii/S1382668923000170

#IBS #Bayer #ToxicPesticides
#Monocrops #Monocrap #BigAg
#BigChem #Poison #RoundUpKills #USPol #WorldPol #Roundup #Glyphosate #Herbicides