#differentiation — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #differentiation, aggregated by home.social.
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Alright, future engineers!
The **Product Rule** differentiates a product of two functions.
Formula: `(fg)' = f'g + fg'`
Pro-Tip: 'First D Second + Second D First' is a classic mnemonic! -
"Always remember that conformity is where tomorrow's greatness goes to die." - Futurist Jim Carroll
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Futurist Jim Carroll is writing his end-of-2025 / introduction-to-2026 series, 26 Principles for 2026. You can follow along at 2026.jimcarroll.com. He welcomes your comments.
---I've long suggested that one of the best ways to align with the future is through this thinking: when everybody is running one way, run the other way!
Be the contrarian. The hole in the bucket, the square peg with a bunch of round holes, the one who says "why not?' when everyone else is saying 'why?'
We are on Day 17. Yesterday, we looked at the terrifying math of the future—the sheer scale of change that is coming. 1-2-4-16-64 vs. 1-2-3-45.
When faced with that kind of overwhelming scale, the natural human instinct is to feel overwhelmed. And I am willing to admit that one reaction I see in common with all of my audiences is that this feeling is universal. I've been doing text-message-based polling from the stage for over 15 years, and one overwhelmingly consistent attitude is that people feel universally overwhelmed by the speed of the future.
So they try to avoid it. They try to fit in. They take the cautious route.
They choose the comfortable over discomfort.
The result? When we feel a need for comfort, to fit in, to follow the herd instinct, we try to be like everyone else. We look for safety in numbers. Case in point: we look at our competitors and say, "Well, they are doing AI this way, so we should too." Korn Ferry made this observation about AI: "Among the most expensive keeping-up-with-the-Joneses games in corporate history."
Need more proof? We seek out "best practices," which is usually just a fancy word for "copying the average."
I rest my case.
In a linear world, fitting in was a survival strategy. You survived by being a cog that fit perfectly into the machine.
In an exponential world, conformity is a death sentence.
Here's why: read the full post at the link below.
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**#Uniqueness** **#Conformity** **#Contrarian** **#Rebellion** **#Innovation** **#Curiosity** **#Differentiation** **#Misfits** **#Authenticity** **#Exponential**
The story of Oblio has defined much of Futurist Jim Carroll’s approach to life.
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"What makes you unique is what will make you successful!" - Futurist Jim Carroll
From one book project to two others!
I'm working away on Escaping Mediocrity, but the other book that is waiting in the wings is "Being Unique."
I've been away from the project for some time, but came to realize that, like the lost Basement Tapes, I've got a lost Chapter 11 of the book that I wrote and misplaced! Since I'm not sure where we stand with the project at this point - I've been away from it for so long - I'm not sure if
I worked it into the most recent 'final' manuscript or not!Reading it, it's a pretty good summary wrap-up for the book, and so I'll share it here!
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The world is moving at a blistering pace. The future isn't just coming - it's accelerating. And in this high-velocity reality, being different isn't just an option - it's your strategic weapon for getting there first.
That much should be clear from reading this book.
The Uniqueness Imperative
With that being the case, here’s the key point you should take away: the safe path to tomorrow is now the riskiest route.
That’s because while others race to conform, real opportunities emerge for those who dare to stand apart.
This isn't just about being different - it's about being ahead.
Consider these realities:
Innovation happens at the edges, where unique thinking flourishes
Breakthroughs come from those who see patterns others miss
The future belongs to those who refuse to fit into today's boxes
Think about how the world works now:
While everyone chases the same opportunities, the unique find new ones
When others seek consensus, the different ones create breakthroughs
As many follow established paths, the distinctive forge new ones
The Strategic Power of Being Different
That’s what you need to keep in mind as you carve out your unique place in the world.
The future marketplace has no room for the ordinary. Every commodity skill is being automated. Every standard approach is being disrupted.
Every conventional wisdom is being challenged.
You need to think about your uniqueness as your strategic superpower: and here’s where your uniqueness becomes strategic:
When you think differently, you see opportunities first
When you act differently, you get to those opportunities faster
When you innovate differently, you create opportunities others miss
And you need to do this at the speed demanded by today’s world.
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Jim’s book, Being Unique — And Why It Will Get to Your Future Faster, will be released sometime during the spring of 2025!
#Uniqueness #Innovation #Strategy #Acceleration #Differentiation #Leadership #Future #Success #Disruption #Opportunity
Original post: https://jimcarroll.com/2025/02/daily-inspiration-being-unique-what-makes-you-unique-is-what-will-make-you-successful/
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Decoding development: #mRNA's role in #embryo formation.
#differentiation #embryogenesis
https://phys.org/news/2024-05-decoding-mrna-role-embryo-formation.html
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#preprint_alert about #astrocytes, the roadies of the brain!
PhD student Imke Schuurmans and team have come up with a comprehensive one-step #differentiation protocol for turning human #iPSCs directly into functional Astrocytes, and how to co-culture them with induced human neurons on multi-electrode arrays for #electrophysiology.
From my new group (Nadif Kasri lab @radboudumc @DondersInst)
Preprint: https://www.biorxiv.org/content/10.1101/2024.03.27.586938v1
Imke's explainer: https://www.linkedin.com/posts/imke-schuurmans-b713a6105_astrocytes-mea-activity-7180850761176645634-qNVm
#neuroscience #cellculture -
From growing #roots, clues to how #stem_cells decide their fate.
#growth #regulation #cell_division #SHR #SCR #differentiation
https://phys.org/news/2024-02-roots-clues-stem-cells-fate.html
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Huiying Shang's preprint is now @PeerCommunityIn --recommended
"Drivers of genomic landscapes of differentiation across Populus divergence gradient"
In this study, we resequenced ~200 individuals from 8 related #species to comparatively investigate the #evolution of genomic landscapes of #diversity and #differentiation through time.
Take a look at it:
https://biorxiv.org/content/10.1101/2021.08.26.457771v6 -
#BRD4-#PRC2 represses #transcription of T-helper 2-specific negative regulators during #Tcell #differentiation:
Brd4 interacts with #Polycomb repressive complex 2 (PRC2) to repress transcriptional expression of T-helper 2 (Th2)-negative regulators #Foxp3 and E3 #ubiqutin #ligase #Fbxw7 during lineage-specific differentiation of #Th2 cells from mouse primary naïve CD4+ T cells
https://www.embopress.org/doi/10.15252/embj.2022111473 -
#BRD4-#PRC2 represses #transcription of T-helper 2-specific negative regulators during #Tcell #differentiation:
Brd4 interacts with #Polycomb repressive complex 2 (PRC2) to repress transcriptional expression of T-helper 2 (Th2)-negative regulators #Foxp3 and E3 #ubiqutin #ligase #Fbxw7 during lineage-specific differentiation of #Th2 cells from mouse primary naïve CD4+ T cells
https://www.embopress.org/doi/10.15252/embj.2022111473 -
#BRD4-#PRC2 represses #transcription of T-helper 2-specific negative regulators during #Tcell #differentiation:
Brd4 interacts with #Polycomb repressive complex 2 (PRC2) to repress transcriptional expression of T-helper 2 (Th2)-negative regulators #Foxp3 and E3 #ubiqutin #ligase #Fbxw7 during lineage-specific differentiation of #Th2 cells from mouse primary naïve CD4+ T cells
https://www.embopress.org/doi/10.15252/embj.2022111473 -
Join us for our upcoming FREE conference!
📆Feb 16, 21, & March 6. ⏰3:30 -5:30pm EST
Please share- all are welcome.
Join the #ALNCrew as well as our keynote speaker @drnickimath
#Math #Math4All #MathTeacher #MathConference #MathPD #MathIntervention #Inclusion #Differentiation -
CW: Combinatorial interpretation of BMP and WNT allows BMP to act as a morphogen in time but not in concentration.
"[...] varying the duration of #BMP #signaling leads to either pluripotent, mesodermal, and extraembryonic states, while varying the concentration does not cause efficient mesodermal differentiation at any dose [...] appropriately timed pulse of BMP induces #hPSCs to a mesodermal fate more efficiently that sustained signaling at any concentration. [...] this effect is due to a combinatorial interpretation of the applied BMP signal and induced endogenous #Wnt signaling."
https://www.biorxiv.org/content/10.1101/2022.11.11.516212v1?rss=1
#DevBio #CellFate #GermLayers #morphogens #Differentiation
