#humangenetics — Public Fediverse posts

The shared evolutionary capacities of plasmids and extrachromosomal DNA

Kuzminov, A. Bacterial nucleoid is a riddle wrapped in a mystery inside an enigma. J. Bacteriol. 206, e0021123…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Agriculture #AnimalGeneticsandGenomics #Biomedicine #Cancergenetics #CancerResearch #Evolutionarygenetics #GeneFunction #general #HumanGenetics #Microbialgenetics #Science
https://www.newsbeep.com/us/847695/

Cohesin prevents local mixing of condensed euchromatic domains in living human cells

All experiments complied with relevant ethical regulations. This study used established human cell lines and involved no human…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Science #Agriculture #AnimalGeneticsandGenomics #Biomedicine #Biophysics #CancerResearch #cellbiology #GeneFunction #general #HumanGenetics
https://www.newsbeep.com/us/841203/

A "cell village" is a novel experimental platform where neural progenitor cells from dozens of genetically distinct donors are grown together in a single, shared culture. This approach allows scientists to accurately measure each donor's individual cell fitness—specifically how well their cells grow, divide, and survive—under perfectly identical environmental conditions.
#HumanGenetics #ComputationalMedicine #Neurobiology #StemCellBiology #Toxicology #sflorg
https://www.sflorg.com/2026/08/gen08042601.html

A "cell village" is a novel experimental platform where neural progenitor cells from dozens of genetically distinct donors are grown together in a single, shared culture. This approach allows scientists to accurately measure each donor's individual cell fitness—specifically how well their cells grow, divide, and survive—under perfectly identical environmental conditions.
#HumanGenetics #ComputationalMedicine #Neurobiology #StemCellBiology #Toxicology #sflorg
https://www.sflorg.com/2026/08/gen08042601.html

A "cell village" is a novel experimental platform where neural progenitor cells from dozens of genetically distinct donors are grown together in a single, shared culture. This approach allows scientists to accurately measure each donor's individual cell fitness—specifically how well their cells grow, divide, and survive—under perfectly identical environmental conditions.
#HumanGenetics #ComputationalMedicine #Neurobiology #StemCellBiology #Toxicology #sflorg
https://www.sflorg.com/2026/08/gen08042601.html

Translating genomic data into healthcare practice with the Singapore National Precision Medicine program

Precision Health Research, Singapore (PRECISE), Singapore, Singapore Shih Wee Seow, Clement Qiwen Sin, Denise Xin Yi Chua, Emily Shu Fang Lau, Gloria…
#NewsBeep #News #Healthcare #Agriculture #AnimalGeneticsandGenomics #AU #Australia #Biomedicine #CancerResearch #GeneFunction #general #Genomics #Health #HumanGenetics #Populationgenetics
https://www.newsbeep.com/au/831818/

A tetraploid wheat pangenome reveals genomic variation and domestication footprints

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This…
#NewsBeep #News #Science #Agriculture #AnimalGeneticsandGenomics #AU #Australia #Biomedicine #CancerResearch #GeneFunction #general #Genomics #HumanGenetics #plantgenetics
https://www.newsbeep.com/au/818300/

SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry

Bostick, M. et al. UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 317, 1760–1764…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Science #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #cellbiology #epigenetics #GeneFunction #general #HumanGenetics
https://www.newsbeep.com/us/777793/

Pervasive interactions between exposures and polygenic risk can inform more effective clinical and behavioral interventions

Lewis, A. C. F. et al. Managing differential performance of polygenic risk scores across groups: real-world ex…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Health #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #GeneFunction #general #Genome-wideassociationstudies #HumanGenetics #metabolicdisorders
https://www.newsbeep.com/us/762200/

#Roche presented more data and testimonials of their #Axelios NGS platform at #ESHG - European Society of #HumanGenetics. Here are my highlights and what it means for the likes of #Illumina, #Element Biosciences and others. open.substack.com/pub/albertvi...

The Dawn of the Axelios Era: R...

Scientists identify hundreds of ancient genes associated with human diseases

When a child develops kidney failure or a rare bone disorder, the cause can seem painfully immediate. It…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Science #ciliopathies #diseasegenes #Evolutionarybiology #healthnews #HumanGenetics #Kidneydisease #LECA #NewDiscoveries #osteopetrosis #proteininteractome #Proteomics #rarediseases #Research
https://www.newsbeep.com/us/672107/

Telomere-to-telomere genome assemblies and population resequencing of diploid and allotetraploid peanut varieties

Assembly and annotation of six representative peanut genomes To determine the genome structure and genetic divers…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Science #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #GeneFunction #general #Genomeassemblyalgorithms #Genome-wideassociationstudies #HumanGenetics
https://www.newsbeep.com/us/607354/

I’ll attend the #EuroNDD Workshop in Warsaw in April. Anyone around the Fediverse going there as well? —> let’s connect!

I’m looking forward to present our work at https://www.findme2care.de AND hear about all the other projects.

Also: I’ll be co-hosting an educational session and roundtable discussion titled „Building Patient Registries under the GDPR – The Good, the Bad and the Ugly“ —> there are a few seats left for conference attendees!

#humangenetics #genetics #RareDiseases #RareDisease #ERN #ERNIthaca #patientregistry

I’ll attend the #EuroNDD Workshop in Warsaw in April. Anyone around the Fediverse going there as well? —> let’s connect!

I’m looking forward to present our work at https://www.findme2care.de AND hear about all the other projects.

Also: I’ll be co-hosting an educational session and roundtable discussion titled „Building Patient Registries under the GDPR – The Good, the Bad and the Ugly“ —> there are a few seats left for conference attendees!

#humangenetics #genetics #RareDiseases #RareDisease #ERN #ERNIthaca #patientregistry

I’ll attend the #EuroNDD Workshop in Warsaw in April. Anyone around the Fediverse going there as well? —> let’s connect!

I’m looking forward to present our work at https://www.findme2care.de AND hear about all the other projects.

Also: I’ll be co-hosting an educational session and roundtable discussion titled „Building Patient Registries under the GDPR – The Good, the Bad and the Ugly“ —> there are a few seats left for conference attendees!

#humangenetics #genetics #RareDiseases #RareDisease #ERN #ERNIthaca #patientregistry

Postdoctoral Fellow Position, Hematology
NIH

See the full job description on jobRxiv: https://jobrxiv.org/job/nih-27778-postdoctoral-fellow-position-hematology/

#genomics #hematology #hematopoiesis #humangenetics #ScienceJobs #hiring #research
https://jobrxiv.org/job/nih-27778-postdoctoral-fellow-position-hematology/?fsp_sid=10193

Postdoctoral Fellow Position, Hematology
NIH

See the full job description on jobRxiv: https://jobrxiv.org/job/nih-27778-postdoctoral-fellow-position-hematology/

#genomics #hematology #hematopoiesis #humangenetics #ScienceJobs #hiring #research
https://jobrxiv.org/job/nih-27778-postdoctoral-fellow-position-hematology/?fsp_sid=10193

Postdoctoral Fellow Position, Hematology
NIH

See the full job description on jobRxiv: https://jobrxiv.org/job/nih-27778-postdoctoral-fellow-position-hematology/

#genomics #hematology #hematopoiesis #humangenetics #ScienceJobs #hiring #research
https://jobrxiv.org/job/nih-27778-postdoctoral-fellow-position-hematology/?fsp_sid=10193

A multi-dimensional framework for establishing and managing a genomic newborn screening program

The above-described methodology resulted in a multi-dimensional framework for a gNBS program consisting of 18 screening criteria (Table 1)…
#NewsBeep #News #Health #AU #Australia #bioinformatics #Biomedicine #Cytogenetics #Ethics #GeneExpression #general #Geneticsresearch #HumanGenetics #MetabolicDisorders #Psychology
https://www.newsbeep.com/au/511045/

Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation

Ethical considerations The current study has been approved by the Swedish Ethical Review Authority (DNR 20…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Health #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #Epidemiology #GeneFunction #general #Geneticassociationstudy #HumanGenetics #microbiology
https://www.newsbeep.com/us/467663/

p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism

Harbeck, N. et al. Breast cancer. Nat. Rev. Dis. Primers 5, 66 (2019). Article  PubMed  Google Scholar  Chen,…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Science #Agriculture #AnimalGeneticsandGenomics #Biomedicine #breastcancer #CancerResearch #GeneFunction #general #HumanGenetics #Metastasis #personalizedmedicine
https://www.newsbeep.com/us/376551/

Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function

Institute of Medical Genetics, University of Zurich, Zurich, Switzerland Reza Asadollahi, Paranchai Boonsawat, Dennis Kra…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #GeneFunction #general #genetictesting #HumanGenetics #Neurodevelopmentaldisorders #Neuroscience #Science
https://www.newsbeep.com/us/244626/

AI Human Genetics Platform Mystra Debuts for Drug Discovery, Validation

Officially unveiled at the American Society of Human Genetics (ASHG) 2025 meeting held in Boston, Genomics has launched…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Artificialintelligence #drugdevelopment(pharmacology) #Drugdiscovery #Genome-wideassociationstudies #genomics #HumanGenetics #mystra #omics #precisionmedicine #Science #topics
https://www.newsbeep.com/us/239086/

Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers

Genetic ancestry is a quantitative measure of inherited genetic variation and correlates with human migration pattern…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #GeneFunction #general #Geneticsresearch #HumanGenetics #personalizedmedicine #Science #Tumourbiomarkers
https://www.newsbeep.com/us/233364/

A postdoctoral position opening in Brest for the Genome of Europe project. #genetics #genomics #HumanGenetics #postdoc

https://www.nature.com/naturecareers/job/12846824/postdoctoral-researcher-in-human-population-genetics

A postdoctoral position opening in Brest for the Genome of Europe project. #genetics #genomics #HumanGenetics #postdoc

https://www.nature.com/naturecareers/job/12846824/postdoctoral-researcher-in-human-population-genetics

A postdoctoral position opening in Brest for the Genome of Europe project. #genetics #genomics #HumanGenetics #postdoc

https://www.nature.com/naturecareers/job/12846824/postdoctoral-researcher-in-human-population-genetics

Oxford Nanopore Announces PromethION Plus Flow Cell and Human Genetics Updates at ASHG 2025

OXFORD, England, October 15, 2025–(BUSINESS WIRE)–At the American Society of Human Genetics (ASHG) 2025 industry session on 16th…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #ASHG #FlowCell #HumanGenetics #humangenomes #OxfordNanoporeTechnologies #PromethION #RareDisease #Science #translationalresearch
https://www.newsbeep.com/us/227138/

Anyone from the #humangenetics #fediverse crowd attending #ESGCT2025 in Seville these days?

We could meet and chat about our projects, genetics, the sciences in the fediverse or just get to know each other in person drinking coffee!

#bioinformatics #genetics #genomics

Anyone from the #humangenetics #fediverse crowd attending #ESGCT2025 in Seville these days?

We could meet and chat about our projects, genetics, the sciences in the fediverse or just get to know each other in person drinking coffee!

#bioinformatics #genetics #genomics

Anyone from the #humangenetics #fediverse crowd attending #ESGCT2025 in Seville these days?

We could meet and chat about our projects, genetics, the sciences in the fediverse or just get to know each other in person drinking coffee!

#bioinformatics #genetics #genomics

A genetic map of human metabolism across the allele frequency spectrum

Study design The UKB is a prospective cohort study from the UK that contains more than 500,000 volunteers…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #Epidemiology #GeneFunction #general #Genome-wideassociationstudies #HumanGenetics #Science
https://www.newsbeep.com/us/199562/

Limited overlap between genetic effects on disease susceptibility and disease survival

Ethics statement This study was conducted in compliance with the relevant ethical guidelines and approved by the appropriate…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #Clinicalgenetics #GeneFunction #general #Geneticassociationstudy #HumanGenetics #Science
https://www.newsbeep.com/us/192762/

Further phenotypical delineation of DLG3-related neurodevelopmental disorders

Elias GM, Elias LAB, Apostolides PF, Kriegstein AR, Nicoll RA. Differential trafficking of AMPA and NMDA receptors by…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Bioinformatics #Biomedicine #Cytogenetics #Diseasegenetics #GeneExpression #general #HumanGenetics #Neurodevelopmentaldisorders #Science
https://www.newsbeep.com/us/174332/

A genomic view of Earth’s biomes

Giovannoni, S., Britschgi, T., Moyer, C. & Field, K. Genetic diversity in Sargasso sea bacterioplankton. Nature 345, 60–63…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #Ecology #GeneFunction #general #genomics #HumanGenetics #Microbialgenetics #Science #Viralgenetics
https://www.newsbeep.com/us/173106/

Regulatory genome annotation | Nature Reviews Genetics

Gerstein, M. B. et al. Architecture of the human regulatory network derived from ENCODE data. Nature 489, 91–100…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #GeneFunction #Generegulatorynetworks #general #HumanGenetics #machinelearning #Science
https://www.newsbeep.com/us/172414/

Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects

Abul-Husn, N. S. & Kenny, E. E. Personalized medicine and the power of electronic health records. Cell 177,…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #GeneFunction #general #Genome-wideassociationstudies #HumanGenetics #Populationgenetics #Science
https://www.newsbeep.com/us/165251/

Clinical exome sequencing efficacy and phenotypic expansions involving non-isolated congenital anomalies of kidney and urinary tract (CAKUT+)

Capone VP, Morello W, Taroni F, Montini G. Genetics of congenital anomalies of the kidney and urinary tract:…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Bioinformatics #Biomedicine #Cytogenetics #development #GeneExpression #general #genetictesting #Geneticsresearch #HumanGenetics #Science
https://www.newsbeep.com/us/136091/

A multi-tissue single-cell expression atlas in cattle

The scope of CattleCA After removing low-quality cells and doublets (Methods, Supplementary Fig. 1 and Supplementary Tables 1…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Genetics #Agriculture #AnimalGeneticsandGenomics #Biomedicine #CancerResearch #Dataprocessing #GeneFunction #general #HumanGenetics #Science #Transcriptomics
https://www.newsbeep.com/us/134393/

https://www.alojapan.com/1279056/the-impact-of-public-insurance-on-rrso-for-hboc-in-japan-a-nationwide-data-study/ The impact of public insurance on RRSO for HBOC in Japan: a nationwide data study #CancerGenetics #GeneExpression #GeneFunction #GeneTherapy #GynaecologicalCancer #HumanGenetics #Japan #JapanNews #JapanTopics #MolecularMedicine #news JOHBOC Registration Committee: Masami Arai (Department of Clinical Genetics, Juntendo University, Graduate School of Medicine, Tokyo, Japan), Seigo Nakamura (Division of Breast Surgical Oncology, Department of Su…

I laughed, as both the target audience and the butt of the joke

#starwarstrivia
#starwars
#HumanGenetics
#epigenetics
#evolution

https://www.smbc-comics.com/comic/lamarcked

I laughed, as both the target audience and the butt of the joke

#starwarstrivia
#starwars
#HumanGenetics
#epigenetics
#evolution

https://www.smbc-comics.com/comic/lamarcked

Auf geht’s Innsbruck #gfh2025 #humangenetics

"The group likely responsible for the Anatolian branch of the Indo-European languages did not share the same genetic makeup as the Yamnaya. Instead, it descended from a distinct but related population, which they identify as the Caucasus–Lower Volga (CLV) group, preceding the Yamnaya and forming part of the earlier expansion of Indo-Anatolian speakers."
The IE Urheimat shifts south of the Steppe.
https://linguisticsandnonsense.wordpress.com/2025/02/18/the-genetic-origins-of-the-indo-europeans-lazaridis-et-al-2025-insights/
#Paleogenetics #AncientDNA #IndoEuropeans #Anatolian #Yamnaya #HumanGenetics

"The group likely responsible for the Anatolian branch of the Indo-European languages did not share the same genetic makeup as the Yamnaya. Instead, it descended from a distinct but related population, which they identify as the Caucasus–Lower Volga (CLV) group, preceding the Yamnaya and forming part of the earlier expansion of Indo-Anatolian speakers."
The IE Urheimat shifts south of the Steppe.
https://linguisticsandnonsense.wordpress.com/2025/02/18/the-genetic-origins-of-the-indo-europeans-lazaridis-et-al-2025-insights/
#Paleogenetics #AncientDNA #IndoEuropeans #Anatolian #Yamnaya #HumanGenetics

If you like thinking and learning about human prehistory, you'll like this interview with geneticist David Reich. Two hours on what research tells us about human origins, how modern humans relate to Neanderthals and Denisovans, ancient DNA, ancient epidemics, admixture, how genetics informs archaeology, and the spread of the Yamnaya from the steppes.

https://m.youtube.com/watch?v=Uj6skZIxPuI

#DavidReich #HumanOrigins #HumanGenetics #HumanEvolution #AncientDNA #OutOfAfrica #Prehistory #Neanderthals #Denisovans

If you like thinking and learning about human prehistory, you'll like this interview with geneticist David Reich. Two hours on what research tells us about human origins, how modern humans relate to Neanderthals and Denisovans, ancient DNA, ancient epidemics, admixture, how genetics informs archaeology, and the spread of the Yamnaya from the steppes.

https://m.youtube.com/watch?v=Uj6skZIxPuI

#DavidReich #HumanOrigins #HumanGenetics #HumanEvolution #AncientDNA #OutOfAfrica #Prehistory #Neanderthals #Denisovans

New publication: "Long genetic and social isolation in Neanderthals before their extinction"

Neanderthal genomes have been recovered from sites across Eurasia, painting an increasingly complex picture of their populations' structure that mostly indicates that late European Neanderthals belonged to a single metapopulation with no significant evidence of population structure. Here, we report the discovery of a late Neanderthal indi... #HumanGenetics https://doi.org/10.1016/j.xgen.2024.100593

The divide between modern humans and our Neanderthal cousins keeps shrinking.

' People with Neanderthal genes didn’t abruptly vanish, Akey says—their offspring just acquired more and more modern human DNA. “They were overwhelmed by waves of modern humans extending out of Africa,” he says. “The modern human population eventually absorbed the Neanderthals.” '

#paleontology #HumanGenetics #anthropology #Neanderthals

https://www.science.org/content/article/neanderthals-and-modern-humans-mingled-early-and-often

The divide between modern humans and our Neanderthal cousins keeps shrinking.

' People with Neanderthal genes didn’t abruptly vanish, Akey says—their offspring just acquired more and more modern human DNA. “They were overwhelmed by waves of modern humans extending out of Africa,” he says. “The modern human population eventually absorbed the Neanderthals.” '

#paleontology #HumanGenetics #anthropology #Neanderthals

https://www.science.org/content/article/neanderthals-and-modern-humans-mingled-early-and-often