#covalentinhibitor — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #covalentinhibitor, aggregated by home.social.
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Interesting paper by the groups of Bradley Pentelute and Aaron Nile in Chemical Science.
They developed an on-resin, intermolecular Heck reaction to diversify acrylamides for covalent hit discovery using covalent peptide-encoded libraries (coPELs).
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Interesting paper by the groups of Bradley Pentelute and Aaron Nile in Chemical Science.
They developed an on-resin, intermolecular Heck reaction to diversify acrylamides for covalent hit discovery using covalent peptide-encoded libraries (coPELs).
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Interesting paper by the groups of Bradley Pentelute and Aaron Nile in Chemical Science.
They developed an on-resin, intermolecular Heck reaction to diversify acrylamides for covalent hit discovery using covalent peptide-encoded libraries (coPELs).
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Interesting paper by the groups of Bradley Pentelute and Aaron Nile in Chemical Science.
They developed an on-resin, intermolecular Heck reaction to diversify acrylamides for covalent hit discovery using covalent peptide-encoded libraries (coPELs).
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Interesting paper by the groups of Bradley Pentelute and Aaron Nile in Chemical Science.
They developed an on-resin, intermolecular Heck reaction to diversify acrylamides for covalent hit discovery using covalent peptide-encoded libraries (coPELs).
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Another interesting #SciComm post by Stan Van Boeckel! K-Ras #DrugDiscovery from being considered #Undruggable to the clinical approval of the #covalent #inhibitor Sotorasib.
#Science #ScienceCommunication #Medicines #StoryTelling #Cancer #KRAS #CovalentInhibitor
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Great talk by Phillip Yesley from the group of Wim Velema at #Lunteren2026.
He discussed the use of mutational profiling to find covalent ligands for structured #RNA using acyl imidazoles as the reactive group.
https://onlinelibrary.wiley.com/doi/10.1002/ange.202517243
#Chemistry #ChemBio #Covalent #CovalentInhibitor -
Very happy that Marnix Roseboom represented our group of the @LED3hub with a very well-attended talk at #NWOCHAINS. He reported on his #PhD work on developing #ChemoProteomics technologies to study #CovalentInhibitor target engagement at arginines.