#covalentinhibitor — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #covalentinhibitor, aggregated by home.social.
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Interesting paper by the groups of Bradley Pentelute and Aaron Nile in Chemical Science.
They developed an on-resin, intermolecular Heck reaction to diversify acrylamides for covalent hit discovery using covalent peptide-encoded libraries (coPELs).
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Interesting paper by the groups of Bradley Pentelute and Aaron Nile in Chemical Science.
They developed an on-resin, intermolecular Heck reaction to diversify acrylamides for covalent hit discovery using covalent peptide-encoded libraries (coPELs).
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Interesting paper by the groups of Bradley Pentelute and Aaron Nile in Chemical Science.
They developed an on-resin, intermolecular Heck reaction to diversify acrylamides for covalent hit discovery using covalent peptide-encoded libraries (coPELs).
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Interesting paper by the groups of Bradley Pentelute and Aaron Nile in Chemical Science.
They developed an on-resin, intermolecular Heck reaction to diversify acrylamides for covalent hit discovery using covalent peptide-encoded libraries (coPELs).
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Interesting paper by the groups of Bradley Pentelute and Aaron Nile in Chemical Science.
They developed an on-resin, intermolecular Heck reaction to diversify acrylamides for covalent hit discovery using covalent peptide-encoded libraries (coPELs).
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Tom Muir
Matthew Disney
Laura Kiessling
Kathrin Lang
Peng Chen
(13/13)#ChemBio #ChemicalBiology #Chemistry #DrugDiscovery #CovalentInhibitor #RNA #Glycotime #ChemicalProteomics #Protein #Imaging #Labeling
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Tom Muir
Matthew Disney
Laura Kiessling
Kathrin Lang
Peng Chen
(13/13)#ChemBio #ChemicalBiology #Chemistry #DrugDiscovery #CovalentInhibitor #RNA #Glycotime #ChemicalProteomics #Protein #Imaging #Labeling
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Tom Muir
Matthew Disney
Laura Kiessling
Kathrin Lang
Peng Chen
(13/13)#ChemBio #ChemicalBiology #Chemistry #DrugDiscovery #CovalentInhibitor #RNA #Glycotime #ChemicalProteomics #Protein #Imaging #Labeling
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Tom Muir
Matthew Disney
Laura Kiessling
Kathrin Lang
Peng Chen
(13/13)#ChemBio #ChemicalBiology #Chemistry #DrugDiscovery #CovalentInhibitor #RNA #Glycotime #ChemicalProteomics #Protein #Imaging #Labeling
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Tom Muir
Matthew Disney
Laura Kiessling
Kathrin Lang
Peng Chen
(13/13)#ChemBio #ChemicalBiology #Chemistry #DrugDiscovery #CovalentInhibitor #RNA #Glycotime #ChemicalProteomics #Protein #Imaging #Labeling
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Congratulations to all authors! (4/4)
#ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #CovalentInhibitor
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Congratulations to all authors! (4/4)
#ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #CovalentInhibitor
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Congratulations to all authors! (4/4)
#ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #CovalentInhibitor
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Congratulations to all authors! (4/4)
#ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Interesting ChemRxiv preprint by the group of Katrin Rittinger. They use enantiomeric pairs of covalent inhibitors to profile ligandable cysteines in the proteome. Interesting use of machine learning to predict new compounds that can add most to the ligandable space.
https://doi.org/10.26434/chemrxiv.15002030/v1
#ChemicalProbes #ChemicalProteomics #ProteoProbes #Chemistry #ChemBio #Ligandability #Cysteine #CovalentInhibitor
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Another interesting #SciComm post by Stan Van Boeckel! K-Ras #DrugDiscovery from being considered #Undruggable to the clinical approval of the #covalent #inhibitor Sotorasib.
#Science #ScienceCommunication #Medicines #StoryTelling #Cancer #KRAS #CovalentInhibitor
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Another interesting #SciComm post by Stan Van Boeckel! K-Ras #DrugDiscovery from being considered #Undruggable to the clinical approval of the #covalent #inhibitor Sotorasib.
#Science #ScienceCommunication #Medicines #StoryTelling #Cancer #KRAS #CovalentInhibitor
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Another interesting #SciComm post by Stan Van Boeckel! K-Ras #DrugDiscovery from being considered #Undruggable to the clinical approval of the #covalent #inhibitor Sotorasib.
#Science #ScienceCommunication #Medicines #StoryTelling #Cancer #KRAS #CovalentInhibitor
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Another interesting #SciComm post by Stan Van Boeckel! K-Ras #DrugDiscovery from being considered #Undruggable to the clinical approval of the #covalent #inhibitor Sotorasib.
#Science #ScienceCommunication #Medicines #StoryTelling #Cancer #KRAS #CovalentInhibitor
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Another interesting #SciComm post by Stan Van Boeckel! K-Ras #DrugDiscovery from being considered #Undruggable to the clinical approval of the #covalent #inhibitor Sotorasib.
#Science #ScienceCommunication #Medicines #StoryTelling #Cancer #KRAS #CovalentInhibitor
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Great talk by Phillip Yesley from the group of Wim Velema at #Lunteren2026.
He discussed the use of mutational profiling to find covalent ligands for structured #RNA using acyl imidazoles as the reactive group.
https://onlinelibrary.wiley.com/doi/10.1002/ange.202517243
#Chemistry #ChemBio #Covalent #CovalentInhibitor -
Great talk by Phillip Yesley from the group of Wim Velema at #Lunteren2026.
He discussed the use of mutational profiling to find covalent ligands for structured #RNA using acyl imidazoles as the reactive group.
https://onlinelibrary.wiley.com/doi/10.1002/ange.202517243
#Chemistry #ChemBio #Covalent #CovalentInhibitor -
Great talk by Phillip Yesley from the group of Wim Velema at #Lunteren2026.
He discussed the use of mutational profiling to find covalent ligands for structured #RNA using acyl imidazoles as the reactive group.
https://onlinelibrary.wiley.com/doi/10.1002/ange.202517243
#Chemistry #ChemBio #Covalent #CovalentInhibitor -
Great talk by Phillip Yesley from the group of Wim Velema at #Lunteren2026.
He discussed the use of mutational profiling to find covalent ligands for structured #RNA using acyl imidazoles as the reactive group.
https://onlinelibrary.wiley.com/doi/10.1002/ange.202517243
#Chemistry #ChemBio #Covalent #CovalentInhibitor -
Very happy that Marnix Roseboom represented our group of the @LED3hub with a very well-attended talk at #NWOCHAINS. He reported on his #PhD work on developing #ChemoProteomics technologies to study #CovalentInhibitor target engagement at arginines.
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Very happy that Marnix Roseboom represented our group of the @LED3hub with a very well-attended talk at #NWOCHAINS. He reported on his #PhD work on developing #ChemoProteomics technologies to study #CovalentInhibitor target engagement at arginines.
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Very happy that Marnix Roseboom represented our group of the @LED3hub with a very well-attended talk at #NWOCHAINS. He reported on his #PhD work on developing #ChemoProteomics technologies to study #CovalentInhibitor target engagement at arginines.
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Very happy that Marnix Roseboom represented our group of the @LED3hub with a very well-attended talk at #NWOCHAINS. He reported on his #PhD work on developing #ChemoProteomics technologies to study #CovalentInhibitor target engagement at arginines.
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A big thank you also to Stacey Paiva and her team at Nature Chemistry for their support and patience with me.
#CovalentInhibitor #DrugDiscovery #Proteomics #ChemicalProteomics #MassSpectrometry #Electrophiles #ProudPI #AcademicLife #NewPublication #Chemistry #ChemBio
(6/7) -
A big thank you also to Stacey Paiva and her team at Nature Chemistry for their support and patience with me.
#CovalentInhibitor #DrugDiscovery #Proteomics #ChemicalProteomics #MassSpectrometry #Electrophiles #ProudPI #AcademicLife #NewPublication #Chemistry #ChemBio
(6/7) -
A big thank you also to Stacey Paiva and her team at Nature Chemistry for their support and patience with me.
#CovalentInhibitor #DrugDiscovery #Proteomics #ChemicalProteomics #MassSpectrometry #Electrophiles #ProudPI #AcademicLife #NewPublication #Chemistry #ChemBio
(6/7) -
A big thank you also to Stacey Paiva and her team at Nature Chemistry for their support and patience with me.
#CovalentInhibitor #DrugDiscovery #Proteomics #ChemicalProteomics #MassSpectrometry #Electrophiles #ProudPI #AcademicLife #NewPublication #Chemistry #ChemBio
(6/7)